The Experts below are selected from a list of 2460 Experts worldwide ranked by ideXlab platform
Jeffery L Miller - One of the best experts on this subject based on the ideXlab platform.
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identification of a cross reacting monoclonal anti human cd233 antibody for identification and sorting of rhesus macaque erythrocytes
Cytometry Part A, 2012Co-Authors: Colleen Byrnes, Terry Y Lee, Robert E Donahue, Jeffery L MillerAbstract:Erythroid biology research involving rhesus macaques has been applied to several topics including malaria, Hemoglobinopathy and gene therapy research. However, analyses of the rhesus red blood cells are limited by the inability to identify and sort those cells in research blood samples using flow cytometry. Here it is reported that the BRIC 6 hybridoma clone raised to the human erythroid surface molecule (referred to as CD233, Band 3, AE1, or SLC4A1) produces cross-reactive and erythroid-specific antibodies for flow cytometric detection and sorting of rhesus macaque erythrocytes.
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identification of a cross reacting monoclonal anti human cd233 antibody for identification and sorting of rhesus macaque erythrocytes
Cytometry Part A, 2012Co-Authors: Colleen Byrnes, Robert E Donahue, Jeffery L MillerAbstract:Erythroid biology research involving rhesus macaques has been applied to several topics including malaria, Hemoglobinopathy and gene therapy research. However, analyses of the rhesus red blood cells are limited by the inability to identify and sort those cells in research blood samples using flow cytometry. Here it is reported that the BRIC 6 hybridoma clone raised to the human erythroid surface molecule (referred to as CD233, Band 3, AE1, or SLC4A1) produces cross-reactive and erythroid-specific antibodies for flow cytometric detection and sorting of rhesus macaque erythrocytes. © 2011 International Society for Advancement of Cytometry
Colleen Byrnes - One of the best experts on this subject based on the ideXlab platform.
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identification of a cross reacting monoclonal anti human cd233 antibody for identification and sorting of rhesus macaque erythrocytes
Cytometry Part A, 2012Co-Authors: Colleen Byrnes, Terry Y Lee, Robert E Donahue, Jeffery L MillerAbstract:Erythroid biology research involving rhesus macaques has been applied to several topics including malaria, Hemoglobinopathy and gene therapy research. However, analyses of the rhesus red blood cells are limited by the inability to identify and sort those cells in research blood samples using flow cytometry. Here it is reported that the BRIC 6 hybridoma clone raised to the human erythroid surface molecule (referred to as CD233, Band 3, AE1, or SLC4A1) produces cross-reactive and erythroid-specific antibodies for flow cytometric detection and sorting of rhesus macaque erythrocytes.
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identification of a cross reacting monoclonal anti human cd233 antibody for identification and sorting of rhesus macaque erythrocytes
Cytometry Part A, 2012Co-Authors: Colleen Byrnes, Robert E Donahue, Jeffery L MillerAbstract:Erythroid biology research involving rhesus macaques has been applied to several topics including malaria, Hemoglobinopathy and gene therapy research. However, analyses of the rhesus red blood cells are limited by the inability to identify and sort those cells in research blood samples using flow cytometry. Here it is reported that the BRIC 6 hybridoma clone raised to the human erythroid surface molecule (referred to as CD233, Band 3, AE1, or SLC4A1) produces cross-reactive and erythroid-specific antibodies for flow cytometric detection and sorting of rhesus macaque erythrocytes. © 2011 International Society for Advancement of Cytometry
Robert E Donahue - One of the best experts on this subject based on the ideXlab platform.
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identification of a cross reacting monoclonal anti human cd233 antibody for identification and sorting of rhesus macaque erythrocytes
Cytometry Part A, 2012Co-Authors: Colleen Byrnes, Terry Y Lee, Robert E Donahue, Jeffery L MillerAbstract:Erythroid biology research involving rhesus macaques has been applied to several topics including malaria, Hemoglobinopathy and gene therapy research. However, analyses of the rhesus red blood cells are limited by the inability to identify and sort those cells in research blood samples using flow cytometry. Here it is reported that the BRIC 6 hybridoma clone raised to the human erythroid surface molecule (referred to as CD233, Band 3, AE1, or SLC4A1) produces cross-reactive and erythroid-specific antibodies for flow cytometric detection and sorting of rhesus macaque erythrocytes.
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identification of a cross reacting monoclonal anti human cd233 antibody for identification and sorting of rhesus macaque erythrocytes
Cytometry Part A, 2012Co-Authors: Colleen Byrnes, Robert E Donahue, Jeffery L MillerAbstract:Erythroid biology research involving rhesus macaques has been applied to several topics including malaria, Hemoglobinopathy and gene therapy research. However, analyses of the rhesus red blood cells are limited by the inability to identify and sort those cells in research blood samples using flow cytometry. Here it is reported that the BRIC 6 hybridoma clone raised to the human erythroid surface molecule (referred to as CD233, Band 3, AE1, or SLC4A1) produces cross-reactive and erythroid-specific antibodies for flow cytometric detection and sorting of rhesus macaque erythrocytes. © 2011 International Society for Advancement of Cytometry
Davy Kieffer - One of the best experts on this subject based on the ideXlab platform.
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evaluation of the v8 e class a novel automated capillary isoelectric focusing instrument for Hemoglobinopathy screening
American Journal of Clinical Pathology, 2016Co-Authors: Toon Schiemsky, Caroline Brusselmans, Elke Nackers, Pieter Vermeersch, Koen Poesen, Koen Desmet, Nancy Boeckx, Davy KiefferAbstract:Objectives: We evaluated the performance of a novel capillary isoelectric focusing (CIEF) application for Hemoglobinopathy screening on the recently introduced V8 E-Class platform. Methods: Analytical performance of the V8 E-Class was evaluated and included assessment of hemoglobin A2 (HbA2) imprecision; linearity for HbA2, fetal hemoglobin (HbF), and sickle hemoglobin (HbS); and carryover for HbS. Furthermore, a method comparison with the Minicap Flex Piercing (Sebia, Lisses, France), the Variant Classic (Bio-Rad Laboratories, Hercules, CA), and the G8 (Tosoh Europe, Amsterdam, the Netherlands) was done to assess analytical and clinical concordance. Results: Total HbA2 imprecision was 3.26% and 3.14% for normal and elevated HbA2 controls and 5.16% and 3.58% for a normal and a heterozygous HbS patient sample, respectively. HbA2, HbF, and HbS showed acceptable linearity, and no carryover was observed. The method comparison showed good analytical concordance ( r > 0.95) except for a homozygous HbS subset ( r = 0.532-0.704). A comparable phenomenon was seen for the clinical concordance with good agreement in samples without variants (weighted κ > 0.80) but poorer agreement in HbS samples (κ < 0.30). Conclusions: Good analytical performance was demonstrated for this novel CIEF application for Hemoglobinopathy screening. Method comparison showed generally good correlation but highlights the need for standardization. Finally, software optimization could further add to its use for routine Hemoglobinopathy screening.
Hikmat Alahmadie - One of the best experts on this subject based on the ideXlab platform.
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renal medullary like carcinoma in an adult without sickle cell Hemoglobinopathy
Nature Reviews Urology, 2010Co-Authors: Peter H Odonnell, Ana R Jensen, Edwin M Posadas, Julia A Bridge, Anjana Yeldandi, Ximing J Yang, Walter M Stadler, Hikmat AlahmadieAbstract:Renal medullary carcinoma has been almost exclusively diagnosed in patients with sickle cell anemia. O'Donnell et al. present a case of this rare and aggressive cancer in an adult with no detectable hemoglobinopathies. They describe both the histopathological features of the disease, and the systemic chemotherapies used to treat it.