Hemorrhagic Fever

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Ziad A. Memish - One of the best experts on this subject based on the ideXlab platform.

  • Dengue Hemorrhagic Fever Virus in Saudi Arabia: A Review.
    Vector borne and zoonotic diseases (Larchmont N.Y.), 2018
    Co-Authors: Jaffar A. Al-tawfiq, Ziad A. Memish
    Abstract:

    Dengue Fever is a global disease with a spectrum of clinical manifestation ranging from mild febrile disease to a severe disease in the form of dengue Hemorrhagic Fever and dengue shock syndrome. Dengue virus is one viral Hemorrhagic Fever that exists in the Kingdom of Saudi Arabia in addition to Alkhurma (Alkhurma) Hemorrhagic Fever, Chikungunya virus, Crimean-Congo Hemorrhagic Fever, and Rift Valley Fever. The disease is limited to the Western and South-western regions of Saudi Arabia, where Aedes aegypti exists. The majority of the cases in Saudi Arabia had mild disease and is related to serotypes 1-3 but not 4. The prospect for Dengue virus control relies on vector control, health education, and possibly vaccine use. Despite extensive collaborative efforts between multiple governmental sectors, including Ministry of Health, Ministry of Municipalities and Rural Affairs, and Ministry of Water, dengue remains a major public health concern in the regions affected.

Tariq A. Madani - One of the best experts on this subject based on the ideXlab platform.

  • Alkhumra virus infection, a new viral Hemorrhagic Fever in Saudi Arabia.
    Journal of Infection, 2005
    Co-Authors: Tariq A. Madani
    Abstract:

    Abstract Objectives Four patients with typical acute viral Hemorrhagic Fever were identified in the holy city of Makkah, Saudi Arabia, between 8 and 23 February 2001, the Hajj (pilgrimage) period of that year. Tests for Rift Valley Fever (RVF), Crimean–Congo Hemorrhagic Fever (CCHF), and dengue were negative. Blood specimens were sent to the Centres for Disease Control and Prevention (CDC), Atlanta for viral culture and testing for other Hemorrhagic Fever viruses. A new flavivirus closely related to the tick-borne Kyasanur forest disease virus was isolated. This new flavivirus was originally isolated in 1995 from 6 patients with dengue-like Hemorrhagic Fever from Alkhumra district, south of Jeddah, Saudi Arabia. Methods A case definition was formulated for surveillance of this new disease in Saudi Arabia. Blood specimens were collected from all patients with suspect ‘Alkhumra’ virus (ALKV) infection and tested for ALKV, RVF, CCHF, dengue, and West Nile encephalitis. Patients data were prospectively collected on standardized data collection forms. Results From 8 February 2001 through 9 February 2003, a total of 37 cases were identified in Makkah, 20 of them were laboratory confirmed. Acute febrile flu-like illness with hepatitis (100%), Hemorrhagic manifestations (55%), and encephalitis (20%) were the main clinical features. The case fatality was 25%. The disease seemed to be transmitted from sheep or goat to humans by the mosquito bites or direct contact with these animals. Conclusions ALKV infection is a novel serious zoonotic Hemorrhagic Fever virus discovered in Saudi Arabia. The role of arthropods such as ticks and mosquitoes, and animals such as sheep, goat, and rodents in the transmission and maintenance of the virus remains to be elucidated.

Nonghua Lu - One of the best experts on this subject based on the ideXlab platform.

  • a retrospective study of acute pancreatitis in patients with Hemorrhagic Fever with renal syndrome
    BMC Gastroenterology, 2013
    Co-Authors: Youxiang Chen, Hao Zeng, Nonghua Lu
    Abstract:

    Etiological diagnosis is an important part of the diagnosis and treatment of acute pancreatitis. Hantavirus infection is a rare cause of acute pancreatitis, which is easy to ignore. There is a need to analyze clinical features of acute pancreatitis caused by Hantavirus. This is a retrospective study conducted from May 1, 2006 to May 31, 2012 on patients diagnosed with Hemorrhagic Fever with renal syndrome at our hospital. We reviewed these patients medical records, laboratory results and radiologic examinations to determine the prevalence and summarize clinical features of acute pancreatitis in patients with Hemorrhagic Fever with renal syndrome. A total of 218 patients were diagnosed with Hemorrhagic Fever with renal syndrome during the 6-year study period. Only 2.8% (6/218) of the total Hemorrhagic Fever with renal syndrome patients were diagnosed with acute pancreatitis. The first symptom for all six of the patients with acute pancreatitis was Fever. All six patients experienced hemorrhage and thrombocytopenia during the disease course, which was different from general acute pancreatitis. In addition, we presented two misdiagnosed clinical cases. Acute pancreatitis is not a frequent complication in patients with Hemorrhagic Fever with renal syndrome. Clinicians should be alerted to the possibility of Hemorrhagic Fever with renal syndrome when acute pancreatitis patients with epidemiological data have high Fever before abdominal pain.

Duane J. Gubler - One of the best experts on this subject based on the ideXlab platform.

  • Dengue and dengue Hemorrhagic Fever - Dengue and Dengue Hemorrhagic Fever
    Clinical microbiology reviews, 1998
    Co-Authors: Duane J. Gubler
    Abstract:

    Dengue Fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity (the cocirculation of multiple serotypes), and the emergence of dengue Hemorrhagic Fever in new geographic regions. In 1998 this mosquito-borne disease is the most important tropical infectious disease after malaria, with an estimated 100 million cases of dengue Fever, 500,000 cases of dengue Hemorrhagic Fever, and 25,000 deaths annually. The reasons for this resurgence and emergence of dengue Hemorrhagic Fever in the waning years of the 20th century are complex and not fully understood, but demographic, societal, and public health infrastructure changes in the past 30 years have contributed greatly. This paper reviews the changing epidemiology of dengue and dengue Hemorrhagic Fever by geographic region, the natural history and transmission cycles, clinical diagnosis of both dengue Fever and dengue Hemorrhagic Fever, serologic and virologic laboratory diagnoses, pathogenesis, surveillance, prevention, and control. A major challenge for public health officials in all tropical areas of the world is to devleop and implement sustainable prevention and control programs that will reverse the trend of emergent dengue Hemorrhagic Fever.

  • dengue and dengue Hemorrhagic Fever
    Clinical Microbiology Reviews, 1998
    Co-Authors: Duane J. Gubler
    Abstract:

    Dengue Fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity (the cocirculation of multiple serotypes), and the emergence of dengue Hemorrhagic Fever in new geographic regions. In 1998 this mosquito-borne disease is the most important tropical infectious disease after malaria, with an estimated 100 million cases of dengue Fever, 500,000 cases of dengue Hemorrhagic Fever, and 25,000 deaths annually. The reasons for this resurgence and emergence of dengue Hemorrhagic Fever in the waning years of the 20th century are complex and not fully understood, but demographic, societal, and public health infrastructure changes in the past 30 years have contributed greatly. This paper reviews the changing epidemiology of dengue and dengue Hemorrhagic Fever by geographic region, the natural history and transmission cycles, clinical diagnosis of both dengue Fever and dengue Hemorrhagic Fever, serologic and virologic laboratory diagnoses, pathogenesis, surveillance, prevention, and control. A major challenge for public health officials in all tropical areas of the world is to devleop and implement sustainable prevention and control programs that will reverse the trend of emergent dengue Hemorrhagic Fever.

Jaffar A. Al-tawfiq - One of the best experts on this subject based on the ideXlab platform.

  • Dengue Hemorrhagic Fever Virus in Saudi Arabia: A Review.
    Vector borne and zoonotic diseases (Larchmont N.Y.), 2018
    Co-Authors: Jaffar A. Al-tawfiq, Ziad A. Memish
    Abstract:

    Dengue Fever is a global disease with a spectrum of clinical manifestation ranging from mild febrile disease to a severe disease in the form of dengue Hemorrhagic Fever and dengue shock syndrome. Dengue virus is one viral Hemorrhagic Fever that exists in the Kingdom of Saudi Arabia in addition to Alkhurma (Alkhurma) Hemorrhagic Fever, Chikungunya virus, Crimean-Congo Hemorrhagic Fever, and Rift Valley Fever. The disease is limited to the Western and South-western regions of Saudi Arabia, where Aedes aegypti exists. The majority of the cases in Saudi Arabia had mild disease and is related to serotypes 1-3 but not 4. The prospect for Dengue virus control relies on vector control, health education, and possibly vaccine use. Despite extensive collaborative efforts between multiple governmental sectors, including Ministry of Health, Ministry of Municipalities and Rural Affairs, and Ministry of Water, dengue remains a major public health concern in the regions affected.