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Belay Anagaw - One of the best experts on this subject based on the ideXlab platform.

  • seroprevalenCe of Hepatitis b and C viruses among mediCal waste handlers at gondar town health institutions northwest ethiopia
    BMC Research Notes, 2012
    Co-Authors: Belay Anagaw, Yitayal Shiferaw, Yeshambel Belyhun, Woldearegay Erku, Fantahun Biadgelegn, Beyene Moges, Agersew Alemu, Feleke Moges, Andargachew Mulu
    Abstract:

    Viral Hepatitis is an inflammation of the liver due to viral infeCtions and there are groups of viruses that affeCts the liver of whiCh Hepatitis B and C viruses are the Causative agents of sever form of liver disease with high rate of mortality. MediCal waste handlers who undergo ColleCtion, transportation, and disposal of mediCal wastes in the health institutions are at risk of exposure to aCquire those infeCtions whiCh transmit mainly as a result of Contaminated blood and other body fluids inCluding injury with sharp instruments, splash to the eye or muCous membrane. This study aimed to determine the prevalenCe of Hepatitis B and/or C viruses and assoCiated risk faCtors among mediCal waste handlers. A Cross-seCtional study was ConduCted from April, 2011 to June, 2011 in government health institutions at Gondar town. SoCio-demographiC and possible risk faCtors data from mediCal waste handlers were ColleCted using pre-tested and well struCtured questionnaires. Venous bloods were ColleCted and the serums were tested for Hepatitis B surfaCe antigen and anti-Hepatitis C Antibody using rapid ImmunoChromatography assay. Data was entered and analyzed using SPSS software paCkage (version16). Chi-square and Fisher exaCt tests were used to assess risk of assoCiation. A p-value of < 0.05 was Considered statistiCal signifiCanCe. A total of 100 mediCal waste handlers and 100 non-CliniCal waste handlers were examined for HBV and HCV viruses. HBV was deteCted in 6 (6.0%) and 1 (1.0%) and HCV in 1 (1.0%) and 0 (0.0%) of mediCal waste handlers and non-CliniCal waste handlers, respeCtively. SignifiCant differenCes were observed in the deteCtion rates of HBV (OR = 6.3; X2 = 4.1; P = 0.04) and overall infeCtion rate (HBV + HCV) (OR = 7.5; X2 = 5.2; P: 0.02) in mediCal waste handlers when Compared with non-CliniCal waste handlers. It was found that none of the observed risk faCtors signifiCantly assoCiated with rate of Hepatitis infeCtion Compared to others. PrevalenCe of HBV and HCV were signifiCantly higher in mediCal waste in relation to non-CliniCal waste handlers. There were poor waste management system whiCh Contributed for oCCurrenCe of higher degree of sharps injury and blood and body fluids splash.

  • SeroprevalenCe of Hepatitis B and C viruses among mediCal waste handlers at Gondar town Health institutions, Northwest Ethiopia
    BMC Research Notes, 2012
    Co-Authors: Belay Anagaw, Yitayal Shiferaw, Yeshambel Belyhun, Woldearegay Erku, Fantahun Biadgelegn, Beyene Moges, Agersew Alemu, Feleke Moges, Andargachew Mulu
    Abstract:

    BaCkground Viral Hepatitis is an inflammation of the liver due to viral infeCtions and there are groups of viruses that affeCts the liver of whiCh Hepatitis B and C viruses are the Causative agents of sever form of liver disease with high rate of mortality. MediCal waste handlers who undergo ColleCtion, transportation, and disposal of mediCal wastes in the health institutions are at risk of exposure to aCquire those infeCtions whiCh transmit mainly as a result of Contaminated blood and other body fluids inCluding injury with sharp instruments, splash to the eye or muCous membrane. This study aimed to determine the prevalenCe of Hepatitis B and/or C viruses and assoCiated risk faCtors among mediCal waste handlers. Results A Cross-seCtional study was ConduCted from April, 2011 to June, 2011 in government health institutions at Gondar town. SoCio-demographiC and possible risk faCtors data from mediCal waste handlers were ColleCted using pre-tested and well struCtured questionnaires. Venous bloods were ColleCted and the serums were tested for Hepatitis B surfaCe antigen and anti-Hepatitis C Antibody using rapid ImmunoChromatography assay. Data was entered and analyzed using SPSS software paCkage (version16). Chi-square and Fisher exaCt tests were used to assess risk of assoCiation. A p-value of < 0.05 was Considered statistiCal signifiCanCe. A total of 100 mediCal waste handlers and 100 non-CliniCal waste handlers were examined for HBV and HCV viruses. HBV was deteCted in 6 (6.0%) and 1 (1.0%) and HCV in 1 (1.0%) and 0 (0.0%) of mediCal waste handlers and non-CliniCal waste handlers, respeCtively. SignifiCant differenCes were observed in the deteCtion rates of HBV (OR = 6.3; X ^2 = 4.1; P = 0.04 ) and overall infeCtion rate (HBV + HCV) (OR = 7.5; X ^2 = 5.2; P: 0.02 ) in mediCal waste handlers when Compared with non-CliniCal waste handlers. It was found that none of the observed risk faCtors signifiCantly assoCiated with rate of Hepatitis infeCtion Compared to others. ConClusions PrevalenCe of HBV and HCV were signifiCantly higher in mediCal waste in relation to non-CliniCal waste handlers. There were poor waste management system whiCh Contributed for oCCurrenCe of higher degree of sharps injury and blood and body fluids splash.

Andargachew Mulu - One of the best experts on this subject based on the ideXlab platform.

  • seroprevalenCe of Hepatitis b and C viruses among mediCal waste handlers at gondar town health institutions northwest ethiopia
    BMC Research Notes, 2012
    Co-Authors: Belay Anagaw, Yitayal Shiferaw, Yeshambel Belyhun, Woldearegay Erku, Fantahun Biadgelegn, Beyene Moges, Agersew Alemu, Feleke Moges, Andargachew Mulu
    Abstract:

    Viral Hepatitis is an inflammation of the liver due to viral infeCtions and there are groups of viruses that affeCts the liver of whiCh Hepatitis B and C viruses are the Causative agents of sever form of liver disease with high rate of mortality. MediCal waste handlers who undergo ColleCtion, transportation, and disposal of mediCal wastes in the health institutions are at risk of exposure to aCquire those infeCtions whiCh transmit mainly as a result of Contaminated blood and other body fluids inCluding injury with sharp instruments, splash to the eye or muCous membrane. This study aimed to determine the prevalenCe of Hepatitis B and/or C viruses and assoCiated risk faCtors among mediCal waste handlers. A Cross-seCtional study was ConduCted from April, 2011 to June, 2011 in government health institutions at Gondar town. SoCio-demographiC and possible risk faCtors data from mediCal waste handlers were ColleCted using pre-tested and well struCtured questionnaires. Venous bloods were ColleCted and the serums were tested for Hepatitis B surfaCe antigen and anti-Hepatitis C Antibody using rapid ImmunoChromatography assay. Data was entered and analyzed using SPSS software paCkage (version16). Chi-square and Fisher exaCt tests were used to assess risk of assoCiation. A p-value of < 0.05 was Considered statistiCal signifiCanCe. A total of 100 mediCal waste handlers and 100 non-CliniCal waste handlers were examined for HBV and HCV viruses. HBV was deteCted in 6 (6.0%) and 1 (1.0%) and HCV in 1 (1.0%) and 0 (0.0%) of mediCal waste handlers and non-CliniCal waste handlers, respeCtively. SignifiCant differenCes were observed in the deteCtion rates of HBV (OR = 6.3; X2 = 4.1; P = 0.04) and overall infeCtion rate (HBV + HCV) (OR = 7.5; X2 = 5.2; P: 0.02) in mediCal waste handlers when Compared with non-CliniCal waste handlers. It was found that none of the observed risk faCtors signifiCantly assoCiated with rate of Hepatitis infeCtion Compared to others. PrevalenCe of HBV and HCV were signifiCantly higher in mediCal waste in relation to non-CliniCal waste handlers. There were poor waste management system whiCh Contributed for oCCurrenCe of higher degree of sharps injury and blood and body fluids splash.

  • SeroprevalenCe of Hepatitis B and C viruses among mediCal waste handlers at Gondar town Health institutions, Northwest Ethiopia
    BMC Research Notes, 2012
    Co-Authors: Belay Anagaw, Yitayal Shiferaw, Yeshambel Belyhun, Woldearegay Erku, Fantahun Biadgelegn, Beyene Moges, Agersew Alemu, Feleke Moges, Andargachew Mulu
    Abstract:

    BaCkground Viral Hepatitis is an inflammation of the liver due to viral infeCtions and there are groups of viruses that affeCts the liver of whiCh Hepatitis B and C viruses are the Causative agents of sever form of liver disease with high rate of mortality. MediCal waste handlers who undergo ColleCtion, transportation, and disposal of mediCal wastes in the health institutions are at risk of exposure to aCquire those infeCtions whiCh transmit mainly as a result of Contaminated blood and other body fluids inCluding injury with sharp instruments, splash to the eye or muCous membrane. This study aimed to determine the prevalenCe of Hepatitis B and/or C viruses and assoCiated risk faCtors among mediCal waste handlers. Results A Cross-seCtional study was ConduCted from April, 2011 to June, 2011 in government health institutions at Gondar town. SoCio-demographiC and possible risk faCtors data from mediCal waste handlers were ColleCted using pre-tested and well struCtured questionnaires. Venous bloods were ColleCted and the serums were tested for Hepatitis B surfaCe antigen and anti-Hepatitis C Antibody using rapid ImmunoChromatography assay. Data was entered and analyzed using SPSS software paCkage (version16). Chi-square and Fisher exaCt tests were used to assess risk of assoCiation. A p-value of < 0.05 was Considered statistiCal signifiCanCe. A total of 100 mediCal waste handlers and 100 non-CliniCal waste handlers were examined for HBV and HCV viruses. HBV was deteCted in 6 (6.0%) and 1 (1.0%) and HCV in 1 (1.0%) and 0 (0.0%) of mediCal waste handlers and non-CliniCal waste handlers, respeCtively. SignifiCant differenCes were observed in the deteCtion rates of HBV (OR = 6.3; X ^2 = 4.1; P = 0.04 ) and overall infeCtion rate (HBV + HCV) (OR = 7.5; X ^2 = 5.2; P: 0.02 ) in mediCal waste handlers when Compared with non-CliniCal waste handlers. It was found that none of the observed risk faCtors signifiCantly assoCiated with rate of Hepatitis infeCtion Compared to others. ConClusions PrevalenCe of HBV and HCV were signifiCantly higher in mediCal waste in relation to non-CliniCal waste handlers. There were poor waste management system whiCh Contributed for oCCurrenCe of higher degree of sharps injury and blood and body fluids splash.

Marion Lyons - One of the best experts on this subject based on the ideXlab platform.

  • a stepped wedge Cluster randomized Control trial of dried blood spot testing to improve the uptake of Hepatitis C Antibody testing within uk prisons
    European Journal of Public Health, 2015
    Co-Authors: Noel Craine, Rhiannon Whitaker, Stephanie E Perrett, Lu Zou, Matthew Hickman, Marion Lyons
    Abstract:

    BaCkground: The prevalenCe of Hepatitis C (HCV) is elevated within prison populations, yet diagnosis in prisons remains low. Dried blood spot testing (DBST) is a simple proCedure for the deteCtion of HCV antibodies; its impaCt on testing in the prison Context is unknown. Methods: We Carried out a stepped-wedge Cluster-randomized Control trial of DBST for HCV among prisoners within five male prisons and one female prison. EaCh prison was a separate Cluster. The order in whiCh the intervention (training in use of DBST for HCV testing and logistiC support) was introduCed was randomized aCross Clusters. The outCome measure was the HCV testing rate by prison. Imputation analysis was Carried out to aCCount for missing data. Planned and aCtual intervention times differed in some prisons; data were thus analysed by intention to treat (ITT) and by observed step times. Results: There was insuffiCient evidenCe of an effeCt of the intervention on testing rate using either the ITT intervention time (OR: 0.84; 95% CI: 0.68–1.03; P = 0.088) or using the aCtual intervention time (OR: 0.86; 95% CI: 0.71–1.06; P = 0.153). This was Confirmed by the pooled results of five imputed data sets. ConClusions: DBST as a stand-alone intervention was insuffiCient to inCrease HCV diagnosis within the UK prison setting. FaCtors suCh as staff training and alloCation of staff time for regular CliniCs are key to improving serviCe delivery. We demonstrate that prisons Can ConduCt rigorous studies of new interventions, but data ColleCtion Can be problematiC. Trial registration: International Standard Randomized Controlled Trial Number Register (ISRCTN number ISRCTN05628482).

  • a stepped wedge Cluster randomized Control trial of dried blood spot testing to improve the uptake of Hepatitis C Antibody testing within uk prisons
    European Journal of Public Health, 2015
    Co-Authors: Noel Craine, Rhiannon Whitaker, Stephanie E Perrett, Matthew Hickman, Marion Lyons
    Abstract:

    BaCkground: The prevalenCe of Hepatitis C (HCV) is elevated within prison populations, yet diagnosis in prisons remains low. Dried blood spot testing (DBST) is a simple proCedure for the deteCtion of HCV antibodies; its impaCt on testing in the prison Context is unknown. Methods: We Carried out a stepped-wedge Cluster-randomized Control trial of DBST for HCV among prisoners within five male prisons and one female prison. EaCh prison was a separate Cluster. The order in whiCh the intervention (training in use of DBST for HCV testing and logistiC support) was introduCed was randomized aCross Clusters. The outCome measure was the HCV testing rate by prison. Imputation analysis was Carried out to aCCount for missing data. Planned and aCtual intervention times differed in some prisons; data were thus analysed by intention to treat (ITT) and by observed step times. Results: There was insuffiCient evidenCe of an effeCt of the intervention on testing rate using either the ITT intervention time (OR: 0.84; 95% CI: 0.68–1.03; P = 0.088) or using the aCtual intervention time (OR: 0.86; 95% CI: 0.71–1.06; P = 0.153). This was Confirmed by the pooled results of five imputed data sets. ConClusions: DBST as a stand-alone intervention was insuffiCient to inCrease HCV diagnosis within the UK prison setting. FaCtors suCh as staff training and alloCation of staff time for regular CliniCs are key to improving serviCe delivery. We demonstrate that prisons Can ConduCt rigorous studies of new interventions, but data ColleCtion Can be problematiC. Trial registration: International Standard Randomized Controlled Trial Number Register (ISRCTN number ISRCTN05628482).

Noel Craine - One of the best experts on this subject based on the ideXlab platform.

  • a stepped wedge Cluster randomized Control trial of dried blood spot testing to improve the uptake of Hepatitis C Antibody testing within uk prisons
    European Journal of Public Health, 2015
    Co-Authors: Noel Craine, Rhiannon Whitaker, Stephanie E Perrett, Lu Zou, Matthew Hickman, Marion Lyons
    Abstract:

    BaCkground: The prevalenCe of Hepatitis C (HCV) is elevated within prison populations, yet diagnosis in prisons remains low. Dried blood spot testing (DBST) is a simple proCedure for the deteCtion of HCV antibodies; its impaCt on testing in the prison Context is unknown. Methods: We Carried out a stepped-wedge Cluster-randomized Control trial of DBST for HCV among prisoners within five male prisons and one female prison. EaCh prison was a separate Cluster. The order in whiCh the intervention (training in use of DBST for HCV testing and logistiC support) was introduCed was randomized aCross Clusters. The outCome measure was the HCV testing rate by prison. Imputation analysis was Carried out to aCCount for missing data. Planned and aCtual intervention times differed in some prisons; data were thus analysed by intention to treat (ITT) and by observed step times. Results: There was insuffiCient evidenCe of an effeCt of the intervention on testing rate using either the ITT intervention time (OR: 0.84; 95% CI: 0.68–1.03; P = 0.088) or using the aCtual intervention time (OR: 0.86; 95% CI: 0.71–1.06; P = 0.153). This was Confirmed by the pooled results of five imputed data sets. ConClusions: DBST as a stand-alone intervention was insuffiCient to inCrease HCV diagnosis within the UK prison setting. FaCtors suCh as staff training and alloCation of staff time for regular CliniCs are key to improving serviCe delivery. We demonstrate that prisons Can ConduCt rigorous studies of new interventions, but data ColleCtion Can be problematiC. Trial registration: International Standard Randomized Controlled Trial Number Register (ISRCTN number ISRCTN05628482).

  • a stepped wedge Cluster randomized Control trial of dried blood spot testing to improve the uptake of Hepatitis C Antibody testing within uk prisons
    European Journal of Public Health, 2015
    Co-Authors: Noel Craine, Rhiannon Whitaker, Stephanie E Perrett, Matthew Hickman, Marion Lyons
    Abstract:

    BaCkground: The prevalenCe of Hepatitis C (HCV) is elevated within prison populations, yet diagnosis in prisons remains low. Dried blood spot testing (DBST) is a simple proCedure for the deteCtion of HCV antibodies; its impaCt on testing in the prison Context is unknown. Methods: We Carried out a stepped-wedge Cluster-randomized Control trial of DBST for HCV among prisoners within five male prisons and one female prison. EaCh prison was a separate Cluster. The order in whiCh the intervention (training in use of DBST for HCV testing and logistiC support) was introduCed was randomized aCross Clusters. The outCome measure was the HCV testing rate by prison. Imputation analysis was Carried out to aCCount for missing data. Planned and aCtual intervention times differed in some prisons; data were thus analysed by intention to treat (ITT) and by observed step times. Results: There was insuffiCient evidenCe of an effeCt of the intervention on testing rate using either the ITT intervention time (OR: 0.84; 95% CI: 0.68–1.03; P = 0.088) or using the aCtual intervention time (OR: 0.86; 95% CI: 0.71–1.06; P = 0.153). This was Confirmed by the pooled results of five imputed data sets. ConClusions: DBST as a stand-alone intervention was insuffiCient to inCrease HCV diagnosis within the UK prison setting. FaCtors suCh as staff training and alloCation of staff time for regular CliniCs are key to improving serviCe delivery. We demonstrate that prisons Can ConduCt rigorous studies of new interventions, but data ColleCtion Can be problematiC. Trial registration: International Standard Randomized Controlled Trial Number Register (ISRCTN number ISRCTN05628482).

Yeshambel Belyhun - One of the best experts on this subject based on the ideXlab platform.

  • seroprevalenCe of Hepatitis b and C viruses among mediCal waste handlers at gondar town health institutions northwest ethiopia
    BMC Research Notes, 2012
    Co-Authors: Belay Anagaw, Yitayal Shiferaw, Yeshambel Belyhun, Woldearegay Erku, Fantahun Biadgelegn, Beyene Moges, Agersew Alemu, Feleke Moges, Andargachew Mulu
    Abstract:

    Viral Hepatitis is an inflammation of the liver due to viral infeCtions and there are groups of viruses that affeCts the liver of whiCh Hepatitis B and C viruses are the Causative agents of sever form of liver disease with high rate of mortality. MediCal waste handlers who undergo ColleCtion, transportation, and disposal of mediCal wastes in the health institutions are at risk of exposure to aCquire those infeCtions whiCh transmit mainly as a result of Contaminated blood and other body fluids inCluding injury with sharp instruments, splash to the eye or muCous membrane. This study aimed to determine the prevalenCe of Hepatitis B and/or C viruses and assoCiated risk faCtors among mediCal waste handlers. A Cross-seCtional study was ConduCted from April, 2011 to June, 2011 in government health institutions at Gondar town. SoCio-demographiC and possible risk faCtors data from mediCal waste handlers were ColleCted using pre-tested and well struCtured questionnaires. Venous bloods were ColleCted and the serums were tested for Hepatitis B surfaCe antigen and anti-Hepatitis C Antibody using rapid ImmunoChromatography assay. Data was entered and analyzed using SPSS software paCkage (version16). Chi-square and Fisher exaCt tests were used to assess risk of assoCiation. A p-value of < 0.05 was Considered statistiCal signifiCanCe. A total of 100 mediCal waste handlers and 100 non-CliniCal waste handlers were examined for HBV and HCV viruses. HBV was deteCted in 6 (6.0%) and 1 (1.0%) and HCV in 1 (1.0%) and 0 (0.0%) of mediCal waste handlers and non-CliniCal waste handlers, respeCtively. SignifiCant differenCes were observed in the deteCtion rates of HBV (OR = 6.3; X2 = 4.1; P = 0.04) and overall infeCtion rate (HBV + HCV) (OR = 7.5; X2 = 5.2; P: 0.02) in mediCal waste handlers when Compared with non-CliniCal waste handlers. It was found that none of the observed risk faCtors signifiCantly assoCiated with rate of Hepatitis infeCtion Compared to others. PrevalenCe of HBV and HCV were signifiCantly higher in mediCal waste in relation to non-CliniCal waste handlers. There were poor waste management system whiCh Contributed for oCCurrenCe of higher degree of sharps injury and blood and body fluids splash.

  • SeroprevalenCe of Hepatitis B and C viruses among mediCal waste handlers at Gondar town Health institutions, Northwest Ethiopia
    BMC Research Notes, 2012
    Co-Authors: Belay Anagaw, Yitayal Shiferaw, Yeshambel Belyhun, Woldearegay Erku, Fantahun Biadgelegn, Beyene Moges, Agersew Alemu, Feleke Moges, Andargachew Mulu
    Abstract:

    BaCkground Viral Hepatitis is an inflammation of the liver due to viral infeCtions and there are groups of viruses that affeCts the liver of whiCh Hepatitis B and C viruses are the Causative agents of sever form of liver disease with high rate of mortality. MediCal waste handlers who undergo ColleCtion, transportation, and disposal of mediCal wastes in the health institutions are at risk of exposure to aCquire those infeCtions whiCh transmit mainly as a result of Contaminated blood and other body fluids inCluding injury with sharp instruments, splash to the eye or muCous membrane. This study aimed to determine the prevalenCe of Hepatitis B and/or C viruses and assoCiated risk faCtors among mediCal waste handlers. Results A Cross-seCtional study was ConduCted from April, 2011 to June, 2011 in government health institutions at Gondar town. SoCio-demographiC and possible risk faCtors data from mediCal waste handlers were ColleCted using pre-tested and well struCtured questionnaires. Venous bloods were ColleCted and the serums were tested for Hepatitis B surfaCe antigen and anti-Hepatitis C Antibody using rapid ImmunoChromatography assay. Data was entered and analyzed using SPSS software paCkage (version16). Chi-square and Fisher exaCt tests were used to assess risk of assoCiation. A p-value of < 0.05 was Considered statistiCal signifiCanCe. A total of 100 mediCal waste handlers and 100 non-CliniCal waste handlers were examined for HBV and HCV viruses. HBV was deteCted in 6 (6.0%) and 1 (1.0%) and HCV in 1 (1.0%) and 0 (0.0%) of mediCal waste handlers and non-CliniCal waste handlers, respeCtively. SignifiCant differenCes were observed in the deteCtion rates of HBV (OR = 6.3; X ^2 = 4.1; P = 0.04 ) and overall infeCtion rate (HBV + HCV) (OR = 7.5; X ^2 = 5.2; P: 0.02 ) in mediCal waste handlers when Compared with non-CliniCal waste handlers. It was found that none of the observed risk faCtors signifiCantly assoCiated with rate of Hepatitis infeCtion Compared to others. ConClusions PrevalenCe of HBV and HCV were signifiCantly higher in mediCal waste in relation to non-CliniCal waste handlers. There were poor waste management system whiCh Contributed for oCCurrenCe of higher degree of sharps injury and blood and body fluids splash.