The Experts below are selected from a list of 237 Experts worldwide ranked by ideXlab platform

Mark Aldenderfer - One of the best experts on this subject based on the ideXlab platform.

Yan Li - One of the best experts on this subject based on the ideXlab platform.

  • genetic convergence in the adaptation of dogs and humans to the High Altitude Environment of the tibetan plateau
    Genome Biology and Evolution, 2014
    Co-Authors: Guodong Wang, Weiwei Zhai, Lu Wang, Li Zhong, Hong Wu, Hechuan Yang, Shifang Wu, Yan Li
    Abstract:

    The High-Altitude hypoxic Environment represents one of the most extreme challenges for mammals. Previous studies of humans on the Tibetan plateau and in the Andes Mountains have identified statistical signatures of selection in different sets of loci. Here, we first measured the hemoglobin levels in village dogs from Tibet and those from Chinese lowlands. We found that the hemoglobin levels are very similar between the two groups, suggesting that Tibetan dogs might share similar adaptive strategies as the Tibetan people. Through a whole-genome sequencing approach, we have identified EPAS1 and HBB as candidate genes for the hypoxic adaptation on the Tibetan plateau. The population genetic analysis shows a significant convergence between humans and dogs in Tibet. The similarities in the sets of loci that exhibit putative signatures of selection and the hemoglobin levels between humans and dogs of the same Environment, but not between human populations in different regions, suggests an extraordinary landscape of convergent evolution between human beings and their best friend on the Tibetan plateau.

Zhu Mingyan - One of the best experts on this subject based on the ideXlab platform.

  • optimization for the starting process of turbofan engine under High Altitude Environment
    IEEE Access, 2018
    Co-Authors: Ma Song, Tan Jiangu, Su Sanmai, Zhu Mingyan
    Abstract:

    The control of the starting process for turbofan engine is a difficult task, especially under High-Altitude and low-temperature Environment, where its characteristics are more complex and strongly nonlinear. In this paper, the working characteristics of the starting process were analyzed and the corresponding mathematical model was established first. In the starting process control problem, since the fuel supply act as the main control parameter, the model of the fuel regulator system was also built. Then, according to the control requirements and combined with models, an optimization expression for minimization of starting time with working and physical constraints was given. The genetic algorithm was utilized to solve the constrained optimization problem and the performance was compared with the classical one that is acquired from actual flight test data. Without exceeding the temperature bound, the starting time can be shortened by about 30%. Moreover, during the unloading process, the starting time in the plateau state and the Highest exhaust temperature are reduced by 18.2% ~ 29.3% and 4.7% ~ 8.6%, respectively.

Weiwei Zhai - One of the best experts on this subject based on the ideXlab platform.

  • genetic convergence in the adaptation of dogs and humans to the High Altitude Environment of the tibetan plateau
    Genome Biology and Evolution, 2014
    Co-Authors: Guodong Wang, Weiwei Zhai, Lu Wang, Li Zhong, Hong Wu, Hechuan Yang, Shifang Wu, Yan Li
    Abstract:

    The High-Altitude hypoxic Environment represents one of the most extreme challenges for mammals. Previous studies of humans on the Tibetan plateau and in the Andes Mountains have identified statistical signatures of selection in different sets of loci. Here, we first measured the hemoglobin levels in village dogs from Tibet and those from Chinese lowlands. We found that the hemoglobin levels are very similar between the two groups, suggesting that Tibetan dogs might share similar adaptive strategies as the Tibetan people. Through a whole-genome sequencing approach, we have identified EPAS1 and HBB as candidate genes for the hypoxic adaptation on the Tibetan plateau. The population genetic analysis shows a significant convergence between humans and dogs in Tibet. The similarities in the sets of loci that exhibit putative signatures of selection and the hemoglobin levels between humans and dogs of the same Environment, but not between human populations in different regions, suggests an extraordinary landscape of convergent evolution between human beings and their best friend on the Tibetan plateau.

Hechuan Yang - One of the best experts on this subject based on the ideXlab platform.

  • genetic convergence in the adaptation of dogs and humans to the High Altitude Environment of the tibetan plateau
    Genome Biology and Evolution, 2014
    Co-Authors: Guodong Wang, Weiwei Zhai, Lu Wang, Li Zhong, Hong Wu, Hechuan Yang, Shifang Wu, Yan Li
    Abstract:

    The High-Altitude hypoxic Environment represents one of the most extreme challenges for mammals. Previous studies of humans on the Tibetan plateau and in the Andes Mountains have identified statistical signatures of selection in different sets of loci. Here, we first measured the hemoglobin levels in village dogs from Tibet and those from Chinese lowlands. We found that the hemoglobin levels are very similar between the two groups, suggesting that Tibetan dogs might share similar adaptive strategies as the Tibetan people. Through a whole-genome sequencing approach, we have identified EPAS1 and HBB as candidate genes for the hypoxic adaptation on the Tibetan plateau. The population genetic analysis shows a significant convergence between humans and dogs in Tibet. The similarities in the sets of loci that exhibit putative signatures of selection and the hemoglobin levels between humans and dogs of the same Environment, but not between human populations in different regions, suggests an extraordinary landscape of convergent evolution between human beings and their best friend on the Tibetan plateau.