The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Xu Zhang - One of the best experts on this subject based on the ideXlab platform.
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silver catalyzed intramolecular Hydroamination of alkynes in aqueous media efficient and regioselective synthesis for fused benzimidazoles
ChemInform, 2011Co-Authors: Xu Zhang, Yu Zhou, Hengshuai Wang, Hualiang Jiang, Hong Liu, Diliang GuoAbstract:AgOTf is shown to be an efficient catalyst for the Hydroamination of alkynes in aqueous solution.
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gold and silver catalyzed intramolecular Hydroamination of terminal alkynes water triggered chemo and regioselective synthesis of fused tricyclic xanthines
Advanced Synthesis & Catalysis, 2009Co-Authors: Xu Zhang, Yu Zhou, Dengyou Zhang, Lei Zhang, Hengshuai Wang, Hualiang Jiang, Hong LiuAbstract:A simple, convenient and green synthetic approach to diverse fused tricyclic xanthines has been developed via gold(I) complex-catalyzed intramolecular Hydroamination or silver(I)-catalyzed isomerization-Hydroamination of terminal alkynes under microwave irradiation in water. The first synthesis of N9-annelated xanthines has also been reported.
Hong Liu - One of the best experts on this subject based on the ideXlab platform.
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silver catalyzed intramolecular Hydroamination of alkynes in aqueous media efficient and regioselective synthesis for fused benzimidazoles
ChemInform, 2011Co-Authors: Xu Zhang, Yu Zhou, Hengshuai Wang, Hualiang Jiang, Hong Liu, Diliang GuoAbstract:AgOTf is shown to be an efficient catalyst for the Hydroamination of alkynes in aqueous solution.
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gold and silver catalyzed intramolecular Hydroamination of terminal alkynes water triggered chemo and regioselective synthesis of fused tricyclic xanthines
Advanced Synthesis & Catalysis, 2009Co-Authors: Xu Zhang, Yu Zhou, Dengyou Zhang, Lei Zhang, Hengshuai Wang, Hualiang Jiang, Hong LiuAbstract:A simple, convenient and green synthetic approach to diverse fused tricyclic xanthines has been developed via gold(I) complex-catalyzed intramolecular Hydroamination or silver(I)-catalyzed isomerization-Hydroamination of terminal alkynes under microwave irradiation in water. The first synthesis of N9-annelated xanthines has also been reported.
Panayiotis A Procopiou - One of the best experts on this subject based on the ideXlab platform.
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heavier alkaline earth catalyzed ene yne cyclizations atom efficient access to tetrahydroisoquinoline frameworks
ChemInform, 2015Co-Authors: Stephanie Reid, Anthony G M Barrett, Michael S Hill, Panayiotis A ProcopiouAbstract:Intermolecular alkene Hydroamination may be coupled with intramolecular alkyne Hydroamination, catalyzed by inexpensive and abundant alkaline earth precatalysts to provide entry to a variety of tetrahydroisoquinoline frameworks.
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heavier alkaline earth catalyzed ene yne cyclizations atom efficient access to tetrahydroisoquinoline frameworks
Organic Letters, 2014Co-Authors: Stephanie Reid, Anthony G M Barrett, Michael S Hill, Panayiotis A ProcopiouAbstract:Tetrahydroisoquinoline frameworks may be accessed with 100% atom efficiency through the alkaline earth catalyzed addition of primary amines to ene-yne substrates through a sequence of intermolecular alkene and intramolecular alkyne Hydroamination steps.
Vy M Dong - One of the best experts on this subject based on the ideXlab platform.
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rhodium catalyzed enantioselective Hydroamination of alkynes with indolines
ChemInform, 2015Co-Authors: Qingan Chen, Zhiwei Chen, Vy M DongAbstract:Branched N-allylic indolines are highly regio- and stereoselectively obtained by Hydroamination of internal alkynes via tandem rhodium catalysis.
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rhodium catalyzed enantioselective Hydroamination of alkynes with indolines
Journal of the American Chemical Society, 2015Co-Authors: Qingan Chen, Zhiwei Chen, Vy M DongAbstract:The Hydroamination of internal alkynes via tandem rhodium catalysis gives branched N-allylic indolines with high regio- and enantioselectivity. An acid switch provides access to the linear isomer in preference to the branched isomer by an isomerization mechanism. Mechanistic studies suggest formation of an allene intermediate, which undergoes Hydroamination to generate allylic amines instead of the enamine or imine products typically observed in alkyne Hydroaminations.
Catharine H Larsen - One of the best experts on this subject based on the ideXlab platform.
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catalytic tandem markovnikov Hydroamination alkynylation and markovnikov Hydroamination hydrovinylation
ChemInform, 2015Co-Authors: Zachary L Palchak, Daniel J Lussier, Conor J Pierce, Hoseong Yoo, Catharine H LarsenAbstract:A tandem Hydroamination-alkynylation reaction to furnish tetrasubstituted propargylic amines is developed.
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catalytic tandem markovnikov Hydroamination alkynylation and markovnikov Hydroamination hydrovinylation
Advanced Synthesis & Catalysis, 2015Co-Authors: Zachary L Palchak, Daniel J Lussier, Conor J Pierce, Hoseong Yoo, Catharine H LarsenAbstract:A tandem Hydroamination–alkynylation was developed as a unique mode of accessing tetrasubstituted propargylic amines. The first equivalent of an alkyne acts as the electrophile in a Markovnikov Hydroamination. The resultant ketimine intermediate is attacked by the second equivalent of alkyne in its nucleophilic copper acetylide form. Studies on the role of each component indicate that the overall reaction is first-order in copper, amine, and alkyne. In addition, a tandem Hydroamination–hydrovinylation provides for an unprecedented one-step synthesis of a 1-amino-1,3-butadiene from phenylacetylene and morpholine.
