Hydroxypropyl Methylcellulose

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Tingting Shen - One of the best experts on this subject based on the ideXlab platform.

  • preparation and properties of a novel thermo sensitive hydrogel based on chitosan Hydroxypropyl Methylcellulose glycerol
    International Journal of Biological Macromolecules, 2016
    Co-Authors: Tao Wang, Liman Chen, Tingting Shen
    Abstract:

    Chitosan-based thermosensitive hydrogels are known as injectable in situ gelling thermosensitive polymer solutions which are suitable for biomaterials. In this study, a novel thermosensitive hydrogel gelling under physiological conditions was prepared using chitosan together with Hydroxypropyl Methylcellulose and glycerol. Hydroxypropyl Methylcellulose is to facilitate the thermogelation through large amounts of hydrophobic interactions. Glycerol in heavy concentration destroys the polymer water sheaths promoting the formation of the hydrophobic regions, and lowering the phase transition temperature. The thermosensitive hydrogels showed a physiological pH ranging from 6.8 to 6.9 and gelation time within 15min at 37°C. The prepared hydrogels were characterized by FT-IR, XRD, SEM, and rheological studies, mechanical studies and contact angle studies. The properties of degradability, cytotoxicity and protein release behaviors of the hydrogels were investigated. The results indicate this thermosensitive hydrogel possess good fluidity, thermosensitivity and biodegradability, as well as low-cytotoxicity and controlled release, showing the potential use in biomedical applications.

Tao Wang - One of the best experts on this subject based on the ideXlab platform.

  • preparation and properties of a novel thermo sensitive hydrogel based on chitosan Hydroxypropyl Methylcellulose glycerol
    International Journal of Biological Macromolecules, 2016
    Co-Authors: Tao Wang, Liman Chen, Tingting Shen
    Abstract:

    Chitosan-based thermosensitive hydrogels are known as injectable in situ gelling thermosensitive polymer solutions which are suitable for biomaterials. In this study, a novel thermosensitive hydrogel gelling under physiological conditions was prepared using chitosan together with Hydroxypropyl Methylcellulose and glycerol. Hydroxypropyl Methylcellulose is to facilitate the thermogelation through large amounts of hydrophobic interactions. Glycerol in heavy concentration destroys the polymer water sheaths promoting the formation of the hydrophobic regions, and lowering the phase transition temperature. The thermosensitive hydrogels showed a physiological pH ranging from 6.8 to 6.9 and gelation time within 15min at 37°C. The prepared hydrogels were characterized by FT-IR, XRD, SEM, and rheological studies, mechanical studies and contact angle studies. The properties of degradability, cytotoxicity and protein release behaviors of the hydrogels were investigated. The results indicate this thermosensitive hydrogel possess good fluidity, thermosensitivity and biodegradability, as well as low-cytotoxicity and controlled release, showing the potential use in biomedical applications.

  • Preparation and properties of a novel thermo-sensitive hydrogel based on chitosan/Hydroxypropyl Methylcellulose/glycerol
    International Journal of Biological Macromolecules, 2016
    Co-Authors: Tao Wang, Chen Liman, Shen Tingting
    Abstract:

    Chitosan-based thermosensitive hydrogels are known as injectable in situ gelling thermosensitive polymer solutions which are suitable for biomaterials. In this study, a novel thermosensitive hydrogel gelling under physiological conditions was prepared using chitosan together with Hydroxypropyl Methylcellulose and glycerol. Hydroxypropyl Methylcellulose is to facilitate the thermogelation through large amounts of hydrophobic interactions. Glycerol in heavy concentration destroys the polymer water sheaths promoting the formation of the hydrophobic regions, and lowering the phase transition temperature. The thermosensitive hydrogels showed a physiological pH ranging from 6.8 to 6.9 and gelation time within 15min at 37°C. The prepared hydrogels were characterized by FT-IR, XRD, SEM, and rheological studies, mechanical studies and contact angle studies. The properties of degradability, cytotoxicity and protein release behaviors of the hydrogels were investigated. The results indicate this thermosensitive hydrogel possess good fluidity, thermosensitivity and biodegradability, as well as low-cytotoxicity and controlled release, showing the potential use in biomedical applications.

Yueming Jiang - One of the best experts on this subject based on the ideXlab platform.

  • Effect of Hydroxypropyl Methylcellulose on the textural and whipping properties of whipped cream
    Food Hydrocolloids, 2009
    Co-Authors: Qiangzhong Zhao, Guowan Su, Jianrong Li, Chun Cui, Bao Yang, Mouming Zhao, Yueming Jiang
    Abstract:

    In this work, Hydroxypropyl Methylcellulose (HPMC) was added into whipped cream for improving its textural and whipping properties. By determination of the particle size distribution, a single peak for the emulsion after homogenization and two distinguishable peaks for the emulsion after whipping for 5 min were observed. With the increase of HPMC level, the average particle size (d3,2) decreased for the emulsion after homogenization and increased for the emulsion after whipping for 5 min. Both whipping time and HPMC level showed positive effects on the partial coalescence of fat globules. The partial coalescence of whipped cream with 0.125% HPMC after whipping for 5 min reached 56.25%, significantly (P 

Liman Chen - One of the best experts on this subject based on the ideXlab platform.

  • preparation and properties of a novel thermo sensitive hydrogel based on chitosan Hydroxypropyl Methylcellulose glycerol
    International Journal of Biological Macromolecules, 2016
    Co-Authors: Tao Wang, Liman Chen, Tingting Shen
    Abstract:

    Chitosan-based thermosensitive hydrogels are known as injectable in situ gelling thermosensitive polymer solutions which are suitable for biomaterials. In this study, a novel thermosensitive hydrogel gelling under physiological conditions was prepared using chitosan together with Hydroxypropyl Methylcellulose and glycerol. Hydroxypropyl Methylcellulose is to facilitate the thermogelation through large amounts of hydrophobic interactions. Glycerol in heavy concentration destroys the polymer water sheaths promoting the formation of the hydrophobic regions, and lowering the phase transition temperature. The thermosensitive hydrogels showed a physiological pH ranging from 6.8 to 6.9 and gelation time within 15min at 37°C. The prepared hydrogels were characterized by FT-IR, XRD, SEM, and rheological studies, mechanical studies and contact angle studies. The properties of degradability, cytotoxicity and protein release behaviors of the hydrogels were investigated. The results indicate this thermosensitive hydrogel possess good fluidity, thermosensitivity and biodegradability, as well as low-cytotoxicity and controlled release, showing the potential use in biomedical applications.

Qiangzhong Zhao - One of the best experts on this subject based on the ideXlab platform.

  • Effect of Hydroxypropyl Methylcellulose on the textural and whipping properties of whipped cream
    Food Hydrocolloids, 2009
    Co-Authors: Qiangzhong Zhao, Guowan Su, Jianrong Li, Chun Cui, Bao Yang, Mouming Zhao, Yueming Jiang
    Abstract:

    In this work, Hydroxypropyl Methylcellulose (HPMC) was added into whipped cream for improving its textural and whipping properties. By determination of the particle size distribution, a single peak for the emulsion after homogenization and two distinguishable peaks for the emulsion after whipping for 5 min were observed. With the increase of HPMC level, the average particle size (d3,2) decreased for the emulsion after homogenization and increased for the emulsion after whipping for 5 min. Both whipping time and HPMC level showed positive effects on the partial coalescence of fat globules. The partial coalescence of whipped cream with 0.125% HPMC after whipping for 5 min reached 56.25%, significantly (P