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Amanda M Castro - One of the best experts on this subject based on the ideXlab platform.

  • dexterity test data contribute to reduction in leaded glovebox gloves use
    Journal Name: Journal of the American Society of Mechanical Engineers and Waste Management 2009 Symposium ; Phoenix Arizona USA ; March 1 2009; Confer, 2009
    Co-Authors: Michael E Cournoyer, Cindy M Lawton, Amanda M Castro, Stephen A Costigan, Stephen B Schreiber
    Abstract:

    Programmatic operations at the Los Alamos National Laboratory Plutonium Facility (T A-55) involve working with various amounts of plutonium and other highly toxic, alpha-emitting materials. The spread of radiological contamination on surfaces, airborne contamination, and excursions of contaminants into the operator's breathing zone are prevented through the use of a variety of gloveboxes. Using an integrated approach, controls have been developed and implemented through an efficient Glovebox Glove Integrity Program. A key element of this program is to consider measures that lower the overall risk of glovebox operations. Line management who own glovebox processes through this program make decisions on which type of glovebox gloves (hereafter referred to as gloves), the weakest component of this safety-significant system, would perform best in these aggressive environments. As Low as Reasonably Achievable considerations must be balanced with glove durability and worker dexterity, both of which affect the final overall risk of the operation. In the past, lead-loaded (leaded) gloves made from Hypalon(reg.) were the primary glove for programmatic operations at TA55. Replacing leaded gloves with unleaded gloves for certain operations would lower the overall risk as well as reduce the amount of mixed transuranic waste. This effort contributes to the Los Alamos National Laboratory Continuous Improvement Program by improving the efficiency, cost-effectiveness, and formality of glovebox operations. In this report, the pros and cons of wearing leaded gloves, the effect of leaded gloves versus unleaded gloves on task performance using standard dexterity tests, the justification for switching from leaded to unleaded gloves, and the pollution prevention benefits of this dramatic change in the glovebox system are presented.

  • Dexterity tests data contribute to reduction in leaded glovebox gloves use
    2008
    Co-Authors: Michael E Cournoyer, Cindy M Lawton, Amanda M Castro
    Abstract:

    Programmatic operations at the Los Alamos National Laboratory Plutonium Facility (TA-55) involve working with various amounts of plutonium and other highly toxic, alphaemitting materials. The spread of radiological contamination on surfaces and airborne contamination and excursions of contaminants into the operator's breathing zone are prevented through the use of a variety of gloveboxes. Through an integrated approach, controls have been developed and implemented through an efficient Glovebox Glove Integrity Program (GGJP). A key element of this program is to consider measures that lower the overall risk of glovebox operations. Line management owning glovebox processes through this program make decisions on which type of glovebox gloves (the weakest component of this safety significant system) would perform in these aggressive environments. As Low As Reasonably Achievable (ALARA) considerations must be balanced with glove durability and worker dexterity, both of which affect the final overall risk of the operation. In the past, lead-loaded (leaded) glovebox gloves made from Hypalon(reg.) had been the workhorse of programmatic operations at TA-55. Replacing leaded gloves with unleaded gloves for certain operations would lower the overall risk as well as reduced the amount of mixed TRU waste. This effort contributes to Los Alamos National Laboratory Continuous Improvement Program by improving the efficiency, cost effectiveness, and formality of glovebox operations. In the following report, the pros and cons of wearing leaded glovebox gloves, the effect of leaded gloves versus unleaded gloves on task performance using standard dexterity tests, the justification for switching from leaded to unleaded gloves, and pollution prevention benefits of this dramatic change in the glovebox system are presented.

Michael E Cournoyer - One of the best experts on this subject based on the ideXlab platform.

  • dexterity test data contribute to reduction in leaded glovebox gloves use
    Journal Name: Journal of the American Society of Mechanical Engineers and Waste Management 2009 Symposium ; Phoenix Arizona USA ; March 1 2009; Confer, 2009
    Co-Authors: Michael E Cournoyer, Cindy M Lawton, Amanda M Castro, Stephen A Costigan, Stephen B Schreiber
    Abstract:

    Programmatic operations at the Los Alamos National Laboratory Plutonium Facility (T A-55) involve working with various amounts of plutonium and other highly toxic, alpha-emitting materials. The spread of radiological contamination on surfaces, airborne contamination, and excursions of contaminants into the operator's breathing zone are prevented through the use of a variety of gloveboxes. Using an integrated approach, controls have been developed and implemented through an efficient Glovebox Glove Integrity Program. A key element of this program is to consider measures that lower the overall risk of glovebox operations. Line management who own glovebox processes through this program make decisions on which type of glovebox gloves (hereafter referred to as gloves), the weakest component of this safety-significant system, would perform best in these aggressive environments. As Low as Reasonably Achievable considerations must be balanced with glove durability and worker dexterity, both of which affect the final overall risk of the operation. In the past, lead-loaded (leaded) gloves made from Hypalon(reg.) were the primary glove for programmatic operations at TA55. Replacing leaded gloves with unleaded gloves for certain operations would lower the overall risk as well as reduce the amount of mixed transuranic waste. This effort contributes to the Los Alamos National Laboratory Continuous Improvement Program by improving the efficiency, cost-effectiveness, and formality of glovebox operations. In this report, the pros and cons of wearing leaded gloves, the effect of leaded gloves versus unleaded gloves on task performance using standard dexterity tests, the justification for switching from leaded to unleaded gloves, and the pollution prevention benefits of this dramatic change in the glovebox system are presented.

  • Dexterity tests data contribute to reduction in leaded glovebox gloves use
    2008
    Co-Authors: Michael E Cournoyer, Cindy M Lawton, Amanda M Castro
    Abstract:

    Programmatic operations at the Los Alamos National Laboratory Plutonium Facility (TA-55) involve working with various amounts of plutonium and other highly toxic, alphaemitting materials. The spread of radiological contamination on surfaces and airborne contamination and excursions of contaminants into the operator's breathing zone are prevented through the use of a variety of gloveboxes. Through an integrated approach, controls have been developed and implemented through an efficient Glovebox Glove Integrity Program (GGJP). A key element of this program is to consider measures that lower the overall risk of glovebox operations. Line management owning glovebox processes through this program make decisions on which type of glovebox gloves (the weakest component of this safety significant system) would perform in these aggressive environments. As Low As Reasonably Achievable (ALARA) considerations must be balanced with glove durability and worker dexterity, both of which affect the final overall risk of the operation. In the past, lead-loaded (leaded) glovebox gloves made from Hypalon(reg.) had been the workhorse of programmatic operations at TA-55. Replacing leaded gloves with unleaded gloves for certain operations would lower the overall risk as well as reduced the amount of mixed TRU waste. This effort contributes to Los Alamos National Laboratory Continuous Improvement Program by improving the efficiency, cost effectiveness, and formality of glovebox operations. In the following report, the pros and cons of wearing leaded glovebox gloves, the effect of leaded gloves versus unleaded gloves on task performance using standard dexterity tests, the justification for switching from leaded to unleaded gloves, and pollution prevention benefits of this dramatic change in the glovebox system are presented.

James V. Rogers - One of the best experts on this subject based on the ideXlab platform.

  • Articles Effect of Drying and Exposure to Vaporous Hydrogen Peroxide on the Inactivation of Highly Pathogenic Avian Influenza (H5N1) on Non-porous Surfaces
    2013
    Co-Authors: James V. Rogers, Young W. Choi, William R. Richte
    Abstract:

    This study demonstrated the combined effect of drying and vaporous hydrogen peroxide exposure on inactivating highly pathogenic avian influenza (H5N1) on the non-porous materials glass, Hypalon ® rubber glove, and stainless steel. Approximately 7.7 log10 TCID50 (median 50 % tissue culture infectious dose)/mL of A/Vietnam/1203/2004 H5N1 in allantoic fluid was dried on coupons of each type of test surface and exposed to vaporous hydrogen peroxide fumigation within a ~15 m 3 chamber. A significant reduction in the total log10 TCID50 of H5N1 on all test materials was observed between the controls evaluated after a 1-hour drying time and unexposed controls evaluated after decontamination. The H5N1 exhibited a 2-3 log decrease in viability, and vaporous hydrogen peroxide further inactivated the virus to below detectable levels. In parallel, Geobacillus stearothermophilus biological indicators exposed to vaporous hydrogen peroxide exhibited no growth after 1 and 7 days ’ incubation. This study provides information on the persistence in viability of H5N1 on non-porous surfaces that can be mitigated by vaporous hydrogen peroxide fumigation of a large chamber

  • Inactivation of Brucella suis, Burkholderia pseudomallei, Francisella tularensis, and Yersinia pestis Using Vaporous Hydrogen Peroxide
    2013
    Co-Authors: James V. Rogers, William R. Richte, Morga Q. S. Wendling, Adrienne M. Shesky
    Abstract:

    This study evaluated the inactivation of Brucella suis, Burkholderia pseudomallei, Francisella tularensis, and Yersinia pestis on glass, Hypalon ® rubber glove, and stainless steel using vaporous hydrogen peroxide fumigation of a ~15 m 3 chamber. A suspension of approximately 1 x 10 8 colony forming units (CFU) of each organism was dried on coupons of each type of test surface and exposed to vaporous hydrogen peroxide. A significant reduction in the log10 CFU of each organism on all test materials was observed between the controls evaluated after a 1-hour drying time and unexposed controls evaluated after decontamination. For all organisms, qualitative growth assessments showed that vaporous hydrogen peroxide exposure completely inactivated bacterial viability on all replicates of the test materials incubated up to 7 days post-exposure. In parallel, all Geobacillus stearothermophilus biological indicators (BI) exposed to vaporous hydrogen peroxide exhibited no growth after 1 and 7 days incubation. This study provides information on using a combination of quantitative and qualitative growth assessments to evaluate vaporous hydrogen peroxide for the surface decontamination of B. suis, B. pseudomallei, F. tularensis, and Y. pestis within a large-scale chamber

  • Articles Large-scale Inactivation of Bacillus anthracis Ames, Vollum, and Sterne Spores Using Vaporous Hydrogen Peroxide
    2012
    Co-Authors: James V. Rogers, William R. Richte, Morga Q. Shaw, Adrienne M. Shesky
    Abstract:

    This study evaluated the inactivation of Bacillus anthracis Ames, Vollum, and Sterne spores on various materials (glass, Hypalon ® rubber glove, and stainless steel) using vaporous hydrogen peroxide fumigation of a ~15 m 3 aerosol research and component assessment (ARCA) chamber. Suspensions of each spore type (~1 x 10 8 CFU) were dried on coupons made from each type of test surface and exposed to vaporous hydrogen peroxide fumigation for a decontamination time of 5.5 hours. For these three materials, the log reductions ranged from 7.7 to 7.9, 8.2 to 8.5, and 7.6 to 7.8 for B. anthracis Ames, Vollum, or Sterne spores, respectively. The effectiveness of vaporous hydrogen peroxide fumigation on the growth of Geobacillus stearothermophilus biological indicators (BI) was evaluated in parallel as a qualitative assessment of decontamination. At 1 and 7 days post-exposure, all decontaminated BI exhibited no growth. This study provides information for using vaporous hydrogen peroxide fumigation as an approach for the surface decontamination of B. anthracis spores within a large-scale chamber

Stephen B Schreiber - One of the best experts on this subject based on the ideXlab platform.

  • dexterity test data contribute to reduction in leaded glovebox gloves use
    Journal Name: Journal of the American Society of Mechanical Engineers and Waste Management 2009 Symposium ; Phoenix Arizona USA ; March 1 2009; Confer, 2009
    Co-Authors: Michael E Cournoyer, Cindy M Lawton, Amanda M Castro, Stephen A Costigan, Stephen B Schreiber
    Abstract:

    Programmatic operations at the Los Alamos National Laboratory Plutonium Facility (T A-55) involve working with various amounts of plutonium and other highly toxic, alpha-emitting materials. The spread of radiological contamination on surfaces, airborne contamination, and excursions of contaminants into the operator's breathing zone are prevented through the use of a variety of gloveboxes. Using an integrated approach, controls have been developed and implemented through an efficient Glovebox Glove Integrity Program. A key element of this program is to consider measures that lower the overall risk of glovebox operations. Line management who own glovebox processes through this program make decisions on which type of glovebox gloves (hereafter referred to as gloves), the weakest component of this safety-significant system, would perform best in these aggressive environments. As Low as Reasonably Achievable considerations must be balanced with glove durability and worker dexterity, both of which affect the final overall risk of the operation. In the past, lead-loaded (leaded) gloves made from Hypalon(reg.) were the primary glove for programmatic operations at TA55. Replacing leaded gloves with unleaded gloves for certain operations would lower the overall risk as well as reduce the amount of mixed transuranic waste. This effort contributes to the Los Alamos National Laboratory Continuous Improvement Program by improving the efficiency, cost-effectiveness, and formality of glovebox operations. In this report, the pros and cons of wearing leaded gloves, the effect of leaded gloves versus unleaded gloves on task performance using standard dexterity tests, the justification for switching from leaded to unleaded gloves, and the pollution prevention benefits of this dramatic change in the glovebox system are presented.

William R. Richte - One of the best experts on this subject based on the ideXlab platform.

  • Articles Effect of Drying and Exposure to Vaporous Hydrogen Peroxide on the Inactivation of Highly Pathogenic Avian Influenza (H5N1) on Non-porous Surfaces
    2013
    Co-Authors: James V. Rogers, Young W. Choi, William R. Richte
    Abstract:

    This study demonstrated the combined effect of drying and vaporous hydrogen peroxide exposure on inactivating highly pathogenic avian influenza (H5N1) on the non-porous materials glass, Hypalon ® rubber glove, and stainless steel. Approximately 7.7 log10 TCID50 (median 50 % tissue culture infectious dose)/mL of A/Vietnam/1203/2004 H5N1 in allantoic fluid was dried on coupons of each type of test surface and exposed to vaporous hydrogen peroxide fumigation within a ~15 m 3 chamber. A significant reduction in the total log10 TCID50 of H5N1 on all test materials was observed between the controls evaluated after a 1-hour drying time and unexposed controls evaluated after decontamination. The H5N1 exhibited a 2-3 log decrease in viability, and vaporous hydrogen peroxide further inactivated the virus to below detectable levels. In parallel, Geobacillus stearothermophilus biological indicators exposed to vaporous hydrogen peroxide exhibited no growth after 1 and 7 days ’ incubation. This study provides information on the persistence in viability of H5N1 on non-porous surfaces that can be mitigated by vaporous hydrogen peroxide fumigation of a large chamber

  • Inactivation of Brucella suis, Burkholderia pseudomallei, Francisella tularensis, and Yersinia pestis Using Vaporous Hydrogen Peroxide
    2013
    Co-Authors: James V. Rogers, William R. Richte, Morga Q. S. Wendling, Adrienne M. Shesky
    Abstract:

    This study evaluated the inactivation of Brucella suis, Burkholderia pseudomallei, Francisella tularensis, and Yersinia pestis on glass, Hypalon ® rubber glove, and stainless steel using vaporous hydrogen peroxide fumigation of a ~15 m 3 chamber. A suspension of approximately 1 x 10 8 colony forming units (CFU) of each organism was dried on coupons of each type of test surface and exposed to vaporous hydrogen peroxide. A significant reduction in the log10 CFU of each organism on all test materials was observed between the controls evaluated after a 1-hour drying time and unexposed controls evaluated after decontamination. For all organisms, qualitative growth assessments showed that vaporous hydrogen peroxide exposure completely inactivated bacterial viability on all replicates of the test materials incubated up to 7 days post-exposure. In parallel, all Geobacillus stearothermophilus biological indicators (BI) exposed to vaporous hydrogen peroxide exhibited no growth after 1 and 7 days incubation. This study provides information on using a combination of quantitative and qualitative growth assessments to evaluate vaporous hydrogen peroxide for the surface decontamination of B. suis, B. pseudomallei, F. tularensis, and Y. pestis within a large-scale chamber

  • Articles Large-scale Inactivation of Bacillus anthracis Ames, Vollum, and Sterne Spores Using Vaporous Hydrogen Peroxide
    2012
    Co-Authors: James V. Rogers, William R. Richte, Morga Q. Shaw, Adrienne M. Shesky
    Abstract:

    This study evaluated the inactivation of Bacillus anthracis Ames, Vollum, and Sterne spores on various materials (glass, Hypalon ® rubber glove, and stainless steel) using vaporous hydrogen peroxide fumigation of a ~15 m 3 aerosol research and component assessment (ARCA) chamber. Suspensions of each spore type (~1 x 10 8 CFU) were dried on coupons made from each type of test surface and exposed to vaporous hydrogen peroxide fumigation for a decontamination time of 5.5 hours. For these three materials, the log reductions ranged from 7.7 to 7.9, 8.2 to 8.5, and 7.6 to 7.8 for B. anthracis Ames, Vollum, or Sterne spores, respectively. The effectiveness of vaporous hydrogen peroxide fumigation on the growth of Geobacillus stearothermophilus biological indicators (BI) was evaluated in parallel as a qualitative assessment of decontamination. At 1 and 7 days post-exposure, all decontaminated BI exhibited no growth. This study provides information for using vaporous hydrogen peroxide fumigation as an approach for the surface decontamination of B. anthracis spores within a large-scale chamber