The Experts below are selected from a list of 1782 Experts worldwide ranked by ideXlab platform

R. Ajit Shenoi - One of the best experts on this subject based on the ideXlab platform.

  • development of a prototype test rig for a cryogenic marine heavy lift buoyancy system
    ASME 2011 30th International Conference on Ocean Offshore and Arctic Engineering, 2011
    Co-Authors: R F Nichollslee, Paul C Mcdonald, R. Ajit Shenoi
    Abstract:

    There is a continual search for new methods of marine salvage and decommissioning of structures in the open sea in order to improve control and lower operational costs. The concept design of a lightweight, cryogenic, marine, heavy lift, buoyancy system has been investigated. The objective is to be able to raise or lower high mass objects controlled solely from a surface support vessel. The overall design concept and associated system development issues have been discussed previously. This work concentrates on the development of a test rig for the cryogenic, marine, heavy lift, buoyancy system and associated test procedures. The main area of concern in the design process is the cryogenic Dewar. This is required to operate at temperatures as low as −196°C but also at pressures exceeding 35bar. A more detailed design of the Dewar, including cryogenic composite materials testing, is considered. The prototype will be assessed through three different testing scenarios; shallow water, open water deep sea, and a Hyperbaric Chamber for very high pressure testing. The procedures for each of these test scenarios is discussed.Copyright © 2011 by ASME

Robert J Alonso - One of the best experts on this subject based on the ideXlab platform.

  • Hyperbaric oxygen therapy in acute ischemic stroke results of the Hyperbaric oxygen in acute ischemic stroke trial pilot study
    Stroke, 2003
    Co-Authors: Daniel E Rusyniak, Mark A Kirk, Jason D May, Louise W Kao, Edward J Brizendine, Julie L Welch, William H Cordell, Robert J Alonso
    Abstract:

    Background and Purpose— Hyperbaric oxygen therapy (HBO) has promise as a treatment for acute stroke. This study was conducted to evaluate the efficacy, safety, and feasibility of using HBO in acute ischemic stroke. Methods— We conducted a randomized, prospective, double-blind, sham-controlled pilot study of 33 patients presenting with acute ischemic stroke who did not receive thrombolytics over a 24-month period. Patients were randomized to treatment for 60 minutes in a monoplace Hyperbaric Chamber pressurized with 100% O2 to 2.5-atm absolute (ATA) in the HBO group or 1.14 ATA in the sham group. Primary outcomes measured included percentage of patients with improvement at 24 hours (National Institutes of Health Stroke Scale [NIHSS]) and 90 days (NIHSS, Barthel Index, modified Rankin Scale, Glasgow Outcome Scale). Secondary measurements included complications of treatment and mortality at 90 days. Results— Baseline demographics were similar in both groups. There were no differences between the groups at 24...

R F Nichollslee - One of the best experts on this subject based on the ideXlab platform.

  • development of a prototype test rig for a cryogenic marine heavy lift buoyancy system
    ASME 2011 30th International Conference on Ocean Offshore and Arctic Engineering, 2011
    Co-Authors: R F Nichollslee, Paul C Mcdonald, R. Ajit Shenoi
    Abstract:

    There is a continual search for new methods of marine salvage and decommissioning of structures in the open sea in order to improve control and lower operational costs. The concept design of a lightweight, cryogenic, marine, heavy lift, buoyancy system has been investigated. The objective is to be able to raise or lower high mass objects controlled solely from a surface support vessel. The overall design concept and associated system development issues have been discussed previously. This work concentrates on the development of a test rig for the cryogenic, marine, heavy lift, buoyancy system and associated test procedures. The main area of concern in the design process is the cryogenic Dewar. This is required to operate at temperatures as low as −196°C but also at pressures exceeding 35bar. A more detailed design of the Dewar, including cryogenic composite materials testing, is considered. The prototype will be assessed through three different testing scenarios; shallow water, open water deep sea, and a Hyperbaric Chamber for very high pressure testing. The procedures for each of these test scenarios is discussed.Copyright © 2011 by ASME

Ingeborg Stalmans - One of the best experts on this subject based on the ideXlab platform.

  • effects of acute atmospheric pressure changes on dynamic contour tonometry and goldmann applanation tonometry in normal individuals a pilot study
    Journal of Glaucoma, 2020
    Co-Authors: Oscar Albisdonado, Brenda Rodriguezcamacho, Shibal Bhartiya, Paulina Ramirezneria, Ellery Lopezstar, Pamela Gonzalezdaher, Mariana Badillofernandez, Ingeborg Stalmans
    Abstract:

    PReCIS:: Intraocular pressure (IOP) measurement differences with Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) are affected by atmospheric pressure inside a Hyperbaric Chamber. PURPOSE To compare IOP measurements obtained with GAT and DCT in 22 normal individuals at different atmospheric pressures simulated in a Hyperbaric Chamber. METHODS The IOP of both eyes of 22 healthy volunteers was measured using GAT and DCT at 4 different atmospheric pressure levels.Starting at 1 Queretaro atmospheric pressure (QATM), the IOP was measured with GAT and DCT. The atmospheric pressure was then increased to 1.1 QATM (equivalent to 1032 m above sea level), 1.2 QATM (equivalent to 315 m above sea level), and 1.25 QATM (equivalent to sea level), starting 5 minutes after reaching each level. The limits of agreement between various measurements with each tonometer were calculated using the Bland-Altman plots. RESULTS The first 4 subjects were used to measure feasibility, consistency, variability, and the time needed for IOP to return to baseline after each atmospheric pressure increase.For the entire 44 eyes, the mean GAT IOP at 1 QATM was 12.23 mm Hg (range, 8 to 20 mm Hg; SD, 2.84) and mean DCT was 16.36 (range, 12.1 to 25.3; SD, 2.84), with a mean 4.14 mm Hg difference (range, -0.1 to 7.5 mm Hg; SD, 1.62; P<0.001).Using the second measurements of the first 4 subjects and those after 5 minutes of adaptation for the rest of the group at 1.1 QATM, mean GAT IOP was 11.05±2.68 mm Hg and mean DCT IOP was 15.60±3.02 mm Hg, for a mean difference between instruments of 4.56±1.81 mm Hg (P<0.001).At 1.2 QATM, mean GAT IOP was 11.14±2.53 mm Hg and mean DCT IOP was 15.39±2.91 mm Hg. The difference between instruments was 4.25±2.12 mm Hg (P<0.001).At 1.25 QATM, the mean GAT IOP was 12.39±3.11 mm Hg and mean DCT IOP was 14.91±2.73 mm Hg. The difference between instruments after 5 minutes of adaptation was 2.53±1.62 mm Hg (P<0.001).Generalized estimating equations for performing linear regression multivariable analysis using atmospheric pressure, expressed as altitude, and age as covariates, shows that the difference between GAT and DCT increases by 1 mm Hg per 673 m of increase of altitude above sea level. Age was not a significant predictor. CONCLUSIONS Acute changes in atmospheric pressure induce changes in IOP measurements for both GAT and DCT and in different directions. Despite the limitation of sample size, it may be postulated that the difference of IOP measurements between the 2 tonometers increases with lower atmospheric pressures.

Paul C Mcdonald - One of the best experts on this subject based on the ideXlab platform.

  • development of a prototype test rig for a cryogenic marine heavy lift buoyancy system
    ASME 2011 30th International Conference on Ocean Offshore and Arctic Engineering, 2011
    Co-Authors: R F Nichollslee, Paul C Mcdonald, R. Ajit Shenoi
    Abstract:

    There is a continual search for new methods of marine salvage and decommissioning of structures in the open sea in order to improve control and lower operational costs. The concept design of a lightweight, cryogenic, marine, heavy lift, buoyancy system has been investigated. The objective is to be able to raise or lower high mass objects controlled solely from a surface support vessel. The overall design concept and associated system development issues have been discussed previously. This work concentrates on the development of a test rig for the cryogenic, marine, heavy lift, buoyancy system and associated test procedures. The main area of concern in the design process is the cryogenic Dewar. This is required to operate at temperatures as low as −196°C but also at pressures exceeding 35bar. A more detailed design of the Dewar, including cryogenic composite materials testing, is considered. The prototype will be assessed through three different testing scenarios; shallow water, open water deep sea, and a Hyperbaric Chamber for very high pressure testing. The procedures for each of these test scenarios is discussed.Copyright © 2011 by ASME