The Experts below are selected from a list of 207 Experts worldwide ranked by ideXlab platform
I. Trotman - One of the best experts on this subject based on the ideXlab platform.
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Treatment of resistant pain in Hypertrophic Pulmonary arthropathy with ketorolac.
Thorax, 1993Co-Authors: N. Blackwell, L. Bangham, M. Hughes, D. Melzack, I. TrotmanAbstract:Pain associated with Hypertrophic Pulmonary Osteoarthropathy (HPOA) may be extremely disabling and resistant to treatment. The successful use of ketorolac, a new non-steroidal anti-inflammatory drug, given by subcutaneous infusion is reported in two patients with uncontrolled pain caused by HPOA.
Walter Vincken - One of the best experts on this subject based on the ideXlab platform.
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Non-small-cell lung cancer with multiple paraneoplastic syndromes
The European respiratory journal, 1995Co-Authors: I Monsieur, M. Meysman, Marc Noppen, J. De Greve, O Delhove, B. Velckeniers, D. Jacobvitz, Walter VinckenAbstract:We describe the case of a patient with multiple paraneoplastic syndromes, six in total, associated with a non-small-cell cancer of the lung. In this single patient we found Hypertrophic Pulmonary Osteoarthropathy, hyperkeratosis of palms and soles, erythema annulare centrifugum, syndrome of inappropriate secretion of antidiuretic hormone (SIADH), and ectopic andrenocorticotrophic hormone (ACTH) and calcitonin production.
Christina Faull - One of the best experts on this subject based on the ideXlab platform.
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Treatment of resistant pain in Hypertrophic Pulmonary Osteoarthropathy with subcutaneous octreotide.
Thorax, 1997Co-Authors: S A Johnson, P A Spiller, Christina FaullAbstract:Pain in Hypertrophic Pulmonary Osteoarthropathy (HPOA) due to periostitis and arthropathy can be a particularly disabling symptom, and resistant to a wide variety of treatments. The effectiveness of subcutaneous octreotide in relieving this pain in a patient with HPOA is reported.
Khalid Amer - One of the best experts on this subject based on the ideXlab platform.
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Effective symptomatic relief of Hypertrophic Pulmonary Osteoarthropathy by video-assisted thoracic surgery truncal vagotomy.
The Annals of thoracic surgery, 2007Co-Authors: Adrian Ooi, Rasheed A. Saad, Narain Moorjani, Khalid AmerAbstract:Various modalities for the treatment of Hypertrophic Pulmonary Osteoarthropathy (HPOA) associated with lung cancer have been suggested since 1958. Although the etiology remains speculative, unilateral vagotomy on the side of the lung cancer achieves symptomatic relief. We report a case of a 50-year-old woman with disabling HPOA and inoperable lung cancer who experienced effective pain relief and regained full mobility after video-assisted thoracoscopic surgery was used to perform truncal vagotomy. This relatively safe and simple procedure should be considered for terminal lung cancer patients with intractable HPOA.
Marsha Gordon - One of the best experts on this subject based on the ideXlab platform.
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Hypertrophic Osteoarthropathy presenting as unilateral cellulitis with successful treatment using pamidronate disodium.
The Journal of clinical and aesthetic dermatology, 2012Co-Authors: Sebastian Bernardo, Jason Emer, Mark E. Burnett, Marsha GordonAbstract:Hypertrophic Pulmonary Osteoarthropathy is a paraneoplastic syndrome seen in patients with lung cancer. This condition is characterized by the presence of digital clubbing, periosteal thickening, synovial thickening, and severe pain of the affected joints. Other syndromes exhibiting clubbing may or may not have underlying diseases causing their manifestation. An example is primary Hypertrophic Osteoarthropathy, or pachydermoperiostosis. While clubbing makes up part of the clinical picture in both Hypertrophic Pulmonary Osteoarthropathy and Hypertrophic Osteoarthropathy, the latter has no underlying disease associations. Rather, primary Hypertrophic Osteoarthropathy is familial, idiopathic, and has a chronic course often beginning during puberty in males. Secondary Hypertrophic Osteoarthropathy is an acquired form of clubbing that is classically associated with lung disease. However, it has also been associated with diseases of the heart, liver, and intestines. In the setting of Pulmonary malignancy, secondary Hypertrophic Osteoarthropathy is known as Hypertrophic Pulmonary Osteoarthropathy. Hypertrophic Pulmonary Osteoarthropathy has a distinct constellation of clinical findings that includes intractable pain often refractory to treatments other than resolution of the underlying disease process. The authors herein report a case of Hypertrophic Pulmonary Osteoarthropathy masquerading as recurrent lower extremity cellulitis with chronic hand and foot pain in the setting of Pulmonary malignancy that responded dramatically to intravenous pamidronate disodium (a bisphosphonate). Given the rarity of Hypertrophic Osteoarthropathy associated with lung cancer and the difficulty with pain management in such circumstances, the authors present the following case in which pain was mitigated by treatment with bisphosphonate therapy.