The Experts below are selected from a list of 1758 Experts worldwide ranked by ideXlab platform

Christina Muccioli - One of the best experts on this subject based on the ideXlab platform.

Seung Uk Lee - One of the best experts on this subject based on the ideXlab platform.

  • The effect of intravitreal bevacizumab injection before Ahmed valve implantation in patients with neovascular glaucoma
    International Ophthalmology, 2014
    Co-Authors: Jung Youb Kang, Ki Yup Nam, Sang Joon Lee, Seung Uk Lee
    Abstract:

    To evaluate the effect of intravitreal bevacizumab (IVB) before Ahmed valve implantation for treatment of neovascular glaucoma (NVG). This study is a retrospective, comparative, consecutive case series. The study group consisted of 27 eyes of 26 patients with NVG who underwent an Ahmed valve implantation. Thirteen eyes were treated with Ahmed valve implantation alone (control group), and 14 eyes were treated with a combination of preoperative IVB injection and Ahmed valve implantation (IVB group). Visual acuity, intraocular pressure (IOP), number of anti-glaucoma medications, surgical complications, and success rate were compared between the two groups. There were no significant differences in preoperative characteristics between the two groups. Visual acuity at 1, 2 weeks, and 1 month after surgery were significantly better in the IVB group ( p  = 0.038, 0.034, and 0.032, respectively). Hyphema associated with Ahmed valve implantation occurred significantly less in the IVB group ( p  = 0.016). On the other hand, the mean IOP and number of anti-glaucoma medications at all follow-up periods were similar between the two groups. Kaplan–Meier survival analysis showed the probability of success 6 months after surgery as 71.4 % in the IVB group and 84.6 % in the control group. No significant difference in success rate was found between the groups ( p  = 0.422). IVB before Ahmed valve implantation for treatment of NVG reduced the incidence of Hyphema. In this retrospective study, IVB provided better visual outcome in the early postoperative periods but did not significantly improve mean IOP, number of anti-glaucoma medications, or success rate.

Mehrdad Malihi - One of the best experts on this subject based on the ideXlab platform.

  • delayed onset symptomatic Hyphema after ab interno trabeculotomy surgery
    American Journal of Ophthalmology, 2012
    Co-Authors: Yachna Ahuja, Mehrdad Malihi
    Abstract:

    PURPOSE: To describe patients who have experienced delayed-onset Hyphema after ab interno trabeculotomy surgery with the Trabectome (Neomedix Corp) for open-angle glaucoma. DESIGN: Retrospective case series. METHODS: study population: Patients at Mayo Clinic, Rochester, Minnesota, who underwent Trabectome surgery between September 1, 2006, and December 31, 2010, and who had symptomatic Hyphema at least 2 months after surgery. observation procedure: Patients with blurred vision at least 2 months after Trabectome surgery were examined for the presence of Hyphema using a slit lamp and gonioscopy. main outcome measures: Proportion of patients experiencing delayed-onset symptomatic Hyphema after Trabectome surgery. Associated factors and clinical course for these patients. RESULTS: Of 262 cases of Trabectome surgery, there were 12 cases of delayed-onset symptomatic Hyphema (4.6%). The average age was 74.3 years (range, 66 to 82 years). Median time to onset of Hyphema was 8.6 months (range, 2 to 31 months) after surgery. Symptom onset commonly occurred on awakening. The most common characteristic was maintaining a sleep position on the surgical side. Most Hyphemas resolved within 1 to 2 weeks, except in 1 patient, who required trabeculectomy for a refractory intraocular pressure spike. CONCLUSIONS: This is a series of patients with symptomatic delayed-onset Hyphema after Trabectome surgery in the absence of further surgeries or trauma. Likely mechanisms are exertion-related increase in episcleral venous pressure or ocular compression from sleeping on the surgical side, followed by sudden decompression and blood reflux. Symptomatic patients should identify and avoid associated triggers because delayed-onset Hyphema may be associated with intermittent intraocular pressure spikes that may require medical or surgical treatment.

Hiroshi Toshida - One of the best experts on this subject based on the ideXlab platform.

  • Iris rubeosis and Hyphema caused by chemical injury due to household detergent.
    Clinical Ophthalmology, 2012
    Co-Authors: Chikako Suto, Tetsuya Ishizuka, Hiroshi Toshida
    Abstract:

    We report an unusual case of iris rubeosis and Hyphema caused by chemical injury due to household detergent. A 74-year-old man with a 15-year history of diabetes mellitus was refilling a container with household detergent at home. He splashed the detergent in his eyes. Slit-lamp examination revealed extensive epithelial damage to the left eye, leading to a persistent corneal epithelial defect. We used a bandage soft contact lens with levofloxacin eye drops as concomitant therapy in order to promote healing. However, a strain of fluoroquinolone-resistant Corynebacterium colonized the eye, so that the corneal ulcer eventually became severe. Use of the bandage soft contact lens was discontinued. His antimicrobial agent was changed to cefmenoxime, a drug to which fluoroquinolone-resistant Corynebacterium is sensitive, and topical instillation of autologous serum subsequently promoted improvement of the ulcer. On day 38 after injury, iris rubeosis led to Hyphema and ghost cell glaucoma. With improvement of his corneal epithelial defect, the iris rubeosis and Hyphema regressed and his visual acuity improved to 20/25 on the left eye. To the best of our knowledge, this is the first report of a case resulting in severe complications due to chemical injury by a neutral detergent. Ophthalmologists should be aware that corneal epithelial damage may become prolonged in elderly patients with diabetes, and unexpectedly severe when wearing bandage soft contact lens, with infection of Corynebacterium resistant to fluoroquinolones, even if the chemical agent is a neutral detergent.

Tsunehiko Ikeda - One of the best experts on this subject based on the ideXlab platform.

  • a case involving an ahmed glaucoma valve transferred from the vitreous into the anterior chamber of the eye with a silicone oil tamponade for the treatment of neovascular glaucoma
    Clinical Ophthalmology, 2013
    Co-Authors: Michiko Miki, Mari Ueki, Tetsuya Sugiyama, Shota Kojima, Tsunehiko Ikeda
    Abstract:

    PURPOSE: To report the short-term efficacy and safety of the transfer of an Ahmed(™) glaucoma valve (AGV™) tube from the vitreous into the anterior chamber, in a patient with neovascular glaucoma who had undergone pars plana AGV(™) implantation and ultimately needed a silicone oil tamponade. CASE: A 41-year-old male with proliferative diabetic retinopathy in both eyes was referred to us for treatment in December 2009. Although the patient previously underwent several surgeries, he ultimately lost vision in his right eye. His left eye suffered from neovascular glaucoma after undergoing a pars plana vitrectomy for tractional retinal detachment. After several vitreous and glaucoma surgeries, the patient underwent implantation of a pars plana AGV™. Postoperatively, although his intraocular pressure was stabilized at approximately 10 mmHg, he had repeated vitreous hemorrhage and Hyphema without improvement. He ultimately underwent PPV with a silicone oil tamponade and at the same time, the AGV™ tube was pulled out from the vitreous and inserted into the anterior chamber in order to avoid complications caused by the silicone oil. RESULTS: At 19 months postoperative, the patient's intraocular pressure had stabilized at 10 mmHg with no recurrence of vitreous hemorrhage and Hyphema. Eventually, he lost vision in his left eye because of cerebral hemorrhage. CONCLUSION: The findings show that insertion of a pars plana AGV™ tube into the anterior chamber in a patient undergoing a silicone oil tamponade is both effective and safe in the short-term.