Hypochlorite

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Nijole A. Remeikis - One of the best experts on this subject based on the ideXlab platform.

  • Effective shelf-life of prepared sodium Hypochlorite solution.
    Journal of Endodontics, 2007
    Co-Authors: Bradford R. Johnson, Nijole A. Remeikis
    Abstract:

    Although the tissue solvent and bactericidal properties of sodium Hypochlorite are well known, the effective shelf-life of prepared sodium Hypochlorite solutions is not known. The stability of sodium Hypochlorite is adversely affected by exposure to high temperature, light, air, and the presence of organic and inorganic contaminants. The purpose of this study was to investigate the variables of storage conditions and time on the tissue-dissolving capacity of three different concentrations of sodium Hypochlorite. Fresh frozen human umbilical cord was used as the tissue sample for this experiment. Tissue samples were dissolved at time intervals ranging from 1 day to 10 wk in 5.25%, 2.62%, and 1.0% solutions of sodium Hypochlorite. The tissue-dissolving ability of 5.25% sodium Hypochlorite remains stable for at least 10 wk. The tissue-dissolving ability of 2.62% and 1.0% sodium Hypochlorite remains relatively stable for 1 wk after mixing, then exhibits a significant decrease in tissue-dissolving ability at 2 wk and beyond.

  • Effective shelf-life of prepared sodium Hypochlorite solution
    Journal of Endodontics, 1993
    Co-Authors: Bradford R. Johnson, Nijole A. Remeikis
    Abstract:

    Although the tissue solvent and bactericidal properties of sodium Hypochlorite are well known, the effective shelf-life of prepared sodium Hypochlorite solutions is not known. The stability of sodium Hypochlorite is adversely affected by exposure to high temperature, light, air, and the presence of organic and inorganic contaminants. The purpose of this study was to investigate the variables of storage conditions and time on the tissue-dissolving capacity of three different concentrations of sodium Hypochlorite. Fresh frozen human umbilical cord was used as the tissue sample for this experiment. Tissue samples were dissolved at time intervals ranging from 1 day to 10 wk in 5.25%, 2.62%, and 1.0% solutions of sodium Hypochlorite. The tissue-dissolving ability of 5.25% sodium Hypochlorite remains stable for at least 10 wk. The tissue-dissolving ability of 2.62% and 1.0% sodium Hypochlorite remains relatively stable for 1 wk after mixing, then exhibits a significant decrease in tissue-dissolving ability at 2 wk and beyond. © 1993 The American Association of Endodontists.

Sonja Stojicic - One of the best experts on this subject based on the ideXlab platform.

  • tissue dissolution by sodium Hypochlorite effect of concentration temperature agitation and surfactant
    Journal of Endodontics, 2010
    Co-Authors: Sonja Stojicic, Slavoljub Zivkovic, Wei Qian, Hui Zhang, Markus Haapasalo
    Abstract:

    Aim: Sodium Hypochlorite is the most commonly used endodontic irrigant because of its antimicrobial and tissue-dissolving activity. The aim of this study was to evaluate and compare the effects of concentration, temperature, and agitation on the tissue-dissolving abilityofsodiumHypochlorite.Inaddition,aHypochlorite product with added surface active agent was compared with conventional Hypochlorite solutions. Methods: Three sodium Hypochlorite solutions from two different manufacturers in concentrations of 1%, 2%, 4%, and 5.8% were tested at room temperature, 37 � C, and 45 � C with and without agitation by ultrasonic and sonic energy and pipetting. Distilled and sterilized tap water was used as controls. Pieces of bovine muscle tissue (68 � 3 mg) were placed in 10 mL of each solution for five minutes. In selected samples, agitation was performed for one, two, or four 15-second periods per each minute. The tissue specimens were weighed before and after treatment, and the percentage of weight loss was calculated. The contact angle on dentin of the three solutions at concentrations of 1% and 5.8% was measured. Results: Weight loss (dissolution) of the tissue increased almost linearly with the concentration of sodium Hypochlorite. Higher temperatures and agitation considerably enhanced the efficacy of sodium Hypochlorite. Theeffect of agitation on tissue dissolution was greater than that of temperature; continuous agitation resulted in the fastest tissue dissolution. Hypochlorite with added surface active agent had the lowest contact angle on dentin and was most effective in tissue dissolution in all experimental situations. Conclusions: Optimizingtheconcentration,temperature,flow,andsurface tension can improve the tissue-dissolving effectiveness ofHypochloriteeven50-fold.(JEndod2010;36:1558‐1562)

Markus Haapasalo - One of the best experts on this subject based on the ideXlab platform.

  • tissue dissolution by sodium Hypochlorite effect of concentration temperature agitation and surfactant
    Journal of Endodontics, 2010
    Co-Authors: Sonja Stojicic, Slavoljub Zivkovic, Wei Qian, Hui Zhang, Markus Haapasalo
    Abstract:

    Aim: Sodium Hypochlorite is the most commonly used endodontic irrigant because of its antimicrobial and tissue-dissolving activity. The aim of this study was to evaluate and compare the effects of concentration, temperature, and agitation on the tissue-dissolving abilityofsodiumHypochlorite.Inaddition,aHypochlorite product with added surface active agent was compared with conventional Hypochlorite solutions. Methods: Three sodium Hypochlorite solutions from two different manufacturers in concentrations of 1%, 2%, 4%, and 5.8% were tested at room temperature, 37 � C, and 45 � C with and without agitation by ultrasonic and sonic energy and pipetting. Distilled and sterilized tap water was used as controls. Pieces of bovine muscle tissue (68 � 3 mg) were placed in 10 mL of each solution for five minutes. In selected samples, agitation was performed for one, two, or four 15-second periods per each minute. The tissue specimens were weighed before and after treatment, and the percentage of weight loss was calculated. The contact angle on dentin of the three solutions at concentrations of 1% and 5.8% was measured. Results: Weight loss (dissolution) of the tissue increased almost linearly with the concentration of sodium Hypochlorite. Higher temperatures and agitation considerably enhanced the efficacy of sodium Hypochlorite. Theeffect of agitation on tissue dissolution was greater than that of temperature; continuous agitation resulted in the fastest tissue dissolution. Hypochlorite with added surface active agent had the lowest contact angle on dentin and was most effective in tissue dissolution in all experimental situations. Conclusions: Optimizingtheconcentration,temperature,flow,andsurface tension can improve the tissue-dissolving effectiveness ofHypochloriteeven50-fold.(JEndod2010;36:1558‐1562)

Bradford R. Johnson - One of the best experts on this subject based on the ideXlab platform.

  • Effective shelf-life of prepared sodium Hypochlorite solution.
    Journal of Endodontics, 2007
    Co-Authors: Bradford R. Johnson, Nijole A. Remeikis
    Abstract:

    Although the tissue solvent and bactericidal properties of sodium Hypochlorite are well known, the effective shelf-life of prepared sodium Hypochlorite solutions is not known. The stability of sodium Hypochlorite is adversely affected by exposure to high temperature, light, air, and the presence of organic and inorganic contaminants. The purpose of this study was to investigate the variables of storage conditions and time on the tissue-dissolving capacity of three different concentrations of sodium Hypochlorite. Fresh frozen human umbilical cord was used as the tissue sample for this experiment. Tissue samples were dissolved at time intervals ranging from 1 day to 10 wk in 5.25%, 2.62%, and 1.0% solutions of sodium Hypochlorite. The tissue-dissolving ability of 5.25% sodium Hypochlorite remains stable for at least 10 wk. The tissue-dissolving ability of 2.62% and 1.0% sodium Hypochlorite remains relatively stable for 1 wk after mixing, then exhibits a significant decrease in tissue-dissolving ability at 2 wk and beyond.

  • Effective shelf-life of prepared sodium Hypochlorite solution
    Journal of Endodontics, 1993
    Co-Authors: Bradford R. Johnson, Nijole A. Remeikis
    Abstract:

    Although the tissue solvent and bactericidal properties of sodium Hypochlorite are well known, the effective shelf-life of prepared sodium Hypochlorite solutions is not known. The stability of sodium Hypochlorite is adversely affected by exposure to high temperature, light, air, and the presence of organic and inorganic contaminants. The purpose of this study was to investigate the variables of storage conditions and time on the tissue-dissolving capacity of three different concentrations of sodium Hypochlorite. Fresh frozen human umbilical cord was used as the tissue sample for this experiment. Tissue samples were dissolved at time intervals ranging from 1 day to 10 wk in 5.25%, 2.62%, and 1.0% solutions of sodium Hypochlorite. The tissue-dissolving ability of 5.25% sodium Hypochlorite remains stable for at least 10 wk. The tissue-dissolving ability of 2.62% and 1.0% sodium Hypochlorite remains relatively stable for 1 wk after mixing, then exhibits a significant decrease in tissue-dissolving ability at 2 wk and beyond. © 1993 The American Association of Endodontists.

J Rennau - One of the best experts on this subject based on the ideXlab platform.