The Experts below are selected from a list of 4320 Experts worldwide ranked by ideXlab platform

Takenori Ogawa - One of the best experts on this subject based on the ideXlab platform.

Takashi Fujii - One of the best experts on this subject based on the ideXlab platform.

  • Matched-pair analysis of patients with advanced Hypopharyngeal Cancer: surgery versus concomitant chemoradiotherapy
    International Journal of Clinical Oncology, 2017
    Co-Authors: Shigemichi Iwae, Takashi Fujii, Kenji Okami, Tetsuro Onitsuka, Masato Fujii, Ryuichi Hayashi, Yasuhisa Hasegawa, Akihiro Homma, Takakuni Kato, Takenori Ogawa
    Abstract:

    Background The aim of this study was to compare the therapeutic outcomes of total pharyngolaryngectomy with those of concomitant chemoradiotherapy in advanced Hypopharyngeal Cancer. Methods This is a retrospective multi-institutional study. The medical records of 979 patients with Hypopharyngeal Cancer, who were initially treated between 2006 and 2008, were reviewed. In this study, we matched a group of total pharyngolaryngectomy patients with a second group of chemoradiotherapy patients, according to age, gender, subsite, arytenoid fixation, cartilage invasion, and N classification, and analyzed overall survival, disease-specific survival, and locoregional control rates. Results The matched-pair analysis included 254 patients. The 5-year overall survival, disease-specific survival, and locoregional control rates were 58.5% and 53.5% ( P  = 0.30), 68.9% and 68.0% ( P  = 0.80), and 82.2% and 63.6% ( P  

  • matched pair analysis of patients with advanced Hypopharyngeal Cancer surgery versus concomitant chemoradiotherapy
    International Journal of Clinical Oncology, 2017
    Co-Authors: Shigemichi Iwae, Takashi Fujii, Kenji Okami, Tetsuro Onitsuka, Masato Fujii, Ryuichi Hayashi, Yasuhisa Hasegawa, Akihiro Homma, Takakuni Kato, Takenori Ogawa
    Abstract:

    Background The aim of this study was to compare the therapeutic outcomes of total pharyngolaryngectomy with those of concomitant chemoradiotherapy in advanced Hypopharyngeal Cancer.

  • Significance of Endoscopic Screening and Endoscopic Resection for Esophageal Cancer in Patients with Hypopharyngeal Cancer
    Japanese journal of clinical oncology, 2010
    Co-Authors: Masahiro Morimoto, Kinji Nishiyama, Satoaki Nakamura, Osamu Suzuki, Yoshifumi Kawaguchi, Aya Nakajima, Atsushi Imai, Ryu Ishihara, Hirokazu Uemura, Takashi Fujii
    Abstract:

    Objective: The efficacy of endoscopic screening for esophageal Cancer in patients with Hypopharyngeal Cancer remains controversial and its impact on prognosis has not been adequately discussed. We studied the use of endoscopic screening to detect esophageal Cancer in Hypopharyngeal Cancer patients by analyzing the incidence, stage and prognosis. Methods: We included 64 patients with Hypopharyngeal Cancer who received radical radiotherapy at our institute. Chromoendoscopic esophageal examinations with Lugol dye solution were routinely performed at and after treatment for Hypopharyngeal Cancer. Results: Twenty-eight esophageal Cancers were detected in 28 (41%) patients (18 synchronous and 10 metachronous Cancers). Of the 28 Cancers, 23 were stage 0 or I Cancer and 15 of these were treated with endoscopic resection. Local control was achieved in all of these 23 stage 0 or I Cancers. The 5-year overall survival rates with esophageal Cancer were 83% in stage 0, 47% in stage I and 0% in stage IIA‐IVB. Conclusions: This study showed a strikingly high incidence of esophageal Cancer in Hypopharyngeal Cancer patients. We suppose that the combination of early detection by chromoendoscopic examination and endoscopic resection for associated esophageal Cancer in Hypopharyngeal Cancer patients improve prognosis and maintain quality of life.

Tetsuro Onitsuka - One of the best experts on this subject based on the ideXlab platform.

Shigemichi Iwae - One of the best experts on this subject based on the ideXlab platform.

Yasuhisa Hasegawa - One of the best experts on this subject based on the ideXlab platform.

  • boerhaave syndrome due to Hypopharyngeal stenosis associated with chemoradiotherapy for Hypopharyngeal Cancer a case report
    Surgical Case Reports, 2018
    Co-Authors: Hideharu Tanaka, Yasuhisa Hasegawa, Norihisa Uemura, Daisuke Nishikawa, Keisuke Oguri, Tetsuya Abe, Eiji Higaki, Takahiro Hosoi, Yasuhiro Shimizu
    Abstract:

    Background Spontaneous esophageal rupture, also known as Boerhaave syndrome, is a very serious life-threatening benign disease of the gastrointestinal tract. It is typically caused by vomiting after heavy eating and drinking. However, in our patient, because of a combination of Hypopharyngeal Cancer with stenosis and chemoradiotherapy (CRT), which caused chemotherapy-induced vomiting, radiotherapy-induced edema, relaxation failure, and delayed reflexes; resistance to the release of increased pressure due to vomiting was exacerbated, thus leading to Boerhaave syndrome. To the best of our knowledge, this is the first report of a patient with esophageal rupture occurring during CRT for Hypopharyngeal Cancer with stenosis.

  • Matched-pair analysis of patients with advanced Hypopharyngeal Cancer: surgery versus concomitant chemoradiotherapy
    International Journal of Clinical Oncology, 2017
    Co-Authors: Shigemichi Iwae, Takashi Fujii, Kenji Okami, Tetsuro Onitsuka, Masato Fujii, Ryuichi Hayashi, Yasuhisa Hasegawa, Akihiro Homma, Takakuni Kato, Takenori Ogawa
    Abstract:

    Background The aim of this study was to compare the therapeutic outcomes of total pharyngolaryngectomy with those of concomitant chemoradiotherapy in advanced Hypopharyngeal Cancer. Methods This is a retrospective multi-institutional study. The medical records of 979 patients with Hypopharyngeal Cancer, who were initially treated between 2006 and 2008, were reviewed. In this study, we matched a group of total pharyngolaryngectomy patients with a second group of chemoradiotherapy patients, according to age, gender, subsite, arytenoid fixation, cartilage invasion, and N classification, and analyzed overall survival, disease-specific survival, and locoregional control rates. Results The matched-pair analysis included 254 patients. The 5-year overall survival, disease-specific survival, and locoregional control rates were 58.5% and 53.5% ( P  = 0.30), 68.9% and 68.0% ( P  = 0.80), and 82.2% and 63.6% ( P  

  • matched pair analysis of patients with advanced Hypopharyngeal Cancer surgery versus concomitant chemoradiotherapy
    International Journal of Clinical Oncology, 2017
    Co-Authors: Shigemichi Iwae, Takashi Fujii, Kenji Okami, Tetsuro Onitsuka, Masato Fujii, Ryuichi Hayashi, Yasuhisa Hasegawa, Akihiro Homma, Takakuni Kato, Takenori Ogawa
    Abstract:

    Background The aim of this study was to compare the therapeutic outcomes of total pharyngolaryngectomy with those of concomitant chemoradiotherapy in advanced Hypopharyngeal Cancer.