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Arzu Saglam - One of the best experts on this subject based on the ideXlab platform.

  • primary ciliary body marginal zone lymphoma presenting as hemorrhagic Hypopyon
    Ocular Immunology and Inflammation, 2020
    Co-Authors: Irem Koc, Hayyam Kiratli, Yasemin Kapucu, Fatma Gundogdu, Arzu Saglam
    Abstract:

    Purpose: Our purpose is to report a patient with primary unilateral ciliary body marginal zone lymphoma who initially presented with hemorrhagic Hypopyon. Methods: Retrospective review of the clinical, imaging, and immunohistopathological features of the case was performed. Results: A 59-year-old man was referred with right anterior uveitis of unknown etiology which was unresponsive to systemic treatment. Slit-lamp biomicroscopy showed normotensive hemorrhagic Hypopyon in that eye. Anterior segment ultrasound biomicroscopy revealed an iridociliary mass lesion. Because an anterior chamber paracentesis was noncontributory, a diagnostic cyclectomy was performed. Histopathological evaluation showed that the neoplastic cells were positive for CD20, lambda light chain, and BCL 2. BCL 6, CD10, CD5, SOX11, kappa, and Cyclin D1 stains were negative. The final diagnosis was extranodal marginal zone lymphoma of the ciliary body. Conclusions: Although rare, ciliary lymphoma may be a cause of intractable anterior uveitis. Repeat biopsies could be carried out when there is a high level of clinical suspicion.

  • primary ciliary body marginal zone lymphoma presenting as hemorrhagic Hypopyon
    Ocular Immunology and Inflammation, 2020
    Co-Authors: Irem Koc, Hayyam Kiratli, Yasemin Kapucu, Fatma Gundogdu, Arzu Saglam
    Abstract:

    Purpose: Our purpose is to report a patient with primary unilateral ciliary body marginal zone lymphoma who initially presented with hemorrhagic Hypopyon. Methods: Retrospective review of the clini...

J. A. Gammon - One of the best experts on this subject based on the ideXlab platform.

  • Pink Hypopyon: a sign of Serratia marcescens endophthalmitis.
    British Journal of Ophthalmology, 1992
    Co-Authors: Selwa A. Al Hazzaa, Khalid F. Tabbara, J. A. Gammon
    Abstract:

    Endogenous bacterial endophthalmitis in infants is uncommon. We recently examined and treated an infant who presented with pink Hypopyon which followed a Serratia marcescens septicaemia. Culture of the aspirate from the anterior chamber showed no red blood cells, and grew Serratia marcescens, which was also isolated from the tip of the child's umbilical artery catheter. The presence of a pink Hypopyon in the absence of hyphaema may suggest the diagnosis of Serratia marcescens endophthalmitis.

Jyotirmay Biswas - One of the best experts on this subject based on the ideXlab platform.

  • tuberculous uveitis presenting as pigmented Hypopyon a case report
    American Journal of Ophthalmology Case Reports, 2017
    Co-Authors: Sachin B Shetty, Santhosh H Devulapally, Sowmiya Murali, Jaydeep Walinjkar, Jyotirmay Biswas
    Abstract:

    Abstract Purpose Hypopyon in the eye is an alarming sign. A case of tuberculous uveitis which presented with pigmented Hypopyon has been described. The aim of this paper is to report pigmented Hypopyon, a rare presentation of tuberculous uveitis in a diabetic patient. Observations A 42-year-old patient with diabetes with a known history of miliary tuberculosis, on anti-tubercular therapy since two months presented with complaints of pain and redness followed by diminution of vision in the right eye since one month. Visual acuity was counting fingers close to face in right eye. Anterior chamber (AC) showed grade 4 cells and flare with a pigmented Hypopyon measuring two mm. Fundus details were not made out. B scan revealed increased choroidal thickness with moderate vitritis. Routine blood counts revealed leucopenia and anemia suggestive of an immunosuppressed state. AC tap analysis was not helpful in diagnosis initially. Patient was lost to follow up and presented one month later with three - fourth of AC having Hypopyon. AC wash was done and the AC sample evaluation revealed acid fast bacilli. Polymerase chain reaction results confirmed it to be Mycobacterium tuberculosis. Conclusions and importance Tuberculous anterior uveitis thus presenting as pigmented Hypopyon is very rare and can cause diagnostic difficulties. High index of suspicion in tuberculosis endemic areas is a must for a prompt diagnosis. A possible association between immunosuppression and pigmented Hypopyon may exist and needs to be studied further.

  • Tuberculous uveitis presenting as pigmented Hypopyon – A case report
    Elsevier, 2017
    Co-Authors: Sachin Shetty B. M.s., Sowmiya Murali, Santhosh H Devulapally, Jaydeep Walinjkar, Jyotirmay Biswas
    Abstract:

    Purpose: Hypopyon in the eye is an alarming sign. A case of tuberculous uveitis which presented with pigmented Hypopyon has been described. The aim of this paper is to report pigmented Hypopyon, a rare presentation of tuberculous uveitis in a diabetic patient. Observations: A 42-year-old patient with diabetes with a known history of miliary tuberculosis, on anti-tubercular therapy since two months presented with complaints of pain and redness followed by diminution of vision in the right eye since one month. Visual acuity was counting fingers close to face in right eye. Anterior chamber (AC) showed grade 4 cells and flare with a pigmented Hypopyon measuring two mm. Fundus details were not made out. B scan revealed increased choroidal thickness with moderate vitritis. Routine blood counts revealed leucopenia and anemia suggestive of an immunosuppressed state. AC tap analysis was not helpful in diagnosis initially. Patient was lost to follow up and presented one month later with three - fourth of AC having Hypopyon. AC wash was done and the AC sample evaluation revealed acid fast bacilli. Polymerase chain reaction results confirmed it to be Mycobacterium tuberculosis. Conclusions and importance: Tuberculous anterior uveitis thus presenting as pigmented Hypopyon is very rare and can cause diagnostic difficulties. High index of suspicion in tuberculosis endemic areas is a must for a prompt diagnosis. A possible association between immunosuppression and pigmented Hypopyon may exist and needs to be studied further

  • bilateral Hypopyon as the presenting feature of chronic myeloid leukemia
    Ocular Immunology and Inflammation, 2008
    Co-Authors: S Sudharshan, Anjana Kumari, Jyotirmay Biswas
    Abstract:

    Purpose: To report bilateral Hypopyon as an unusual presenting feature of chronic myeloid leukemia (CML). Design: Observational case report. Methods: A 68-year-old male presenting with bilateral Hypopyon uveitis underwent hematological investigations and cytology of Hypopyon. Results: Blood smear revealed increased leucocyte count with presence of abnormal cells (myelocytes, band forms, and promyelocytes) suggestive of CML. Cytopathology of Hypopyon revealed predominance of lymphocytes and few plasma cells. CML was confirmed by hematological investigations. Patient was initiated on chemotherapy under the care of an oncologist and is stable. Conclusions: Elderly patients presenting with Hypopyon uveitis should be investigated to rule out masquerade syndrome.

Richard W Green - One of the best experts on this subject based on the ideXlab platform.

  • endogenous serratia marcescens endophthalmitis with dark Hypopyon a case report and review
    Survey of Ophthalmology, 2001
    Co-Authors: Robert A Equi, Richard W Green
    Abstract:

    A case of endogenous Serratia marcescens endophthalmitis in a patient with diabetes, end-stage renal disease, and an indwelling venous catheter is reported. The patient presented with a tan Hypopyon and elevated intraocular pressure. Diagnosis was established by positive blood, vitreous, conjunctival, and catheter tip cultures. After a deteriorating course the eye was enucleated. Gross and histopathologic examination revealed the presence of a dark Hypopyon with iris necrosis and pigment dispersion and possible spontaneous globe perforation. This is the eleventh reported case of endogenous Serratia endophthalmitis. Previous association of a pink Hypopyon and of pigmented vitreous fluid and Serratia endophthalmitis has been reported. This is the first case of dark Hypopyon in endogenous Serratia marcescens endophthalmitis reported in the medical literature. Previous entities associated with dark Hypopyon have been limited to intraocular melanoma and Listeria monocytogenes endophthalmitis. Dark Hypopyon in the appropriate clinical setting may be useful in aiding diagnostic and therapeutic decisions.

  • elevated intraocular pressure pigment dispersion and dark Hypopyon in endogenous endophthalmitis from listeria monocytogenes
    Survey of Ophthalmology, 1992
    Co-Authors: Dean Eliott, Richard W Green, Terrence P Obrien, Henry D Jampel, Morton F Goldberg
    Abstract:

    Listeria monocytogenes endophthalmitis occurred in an immunologically competent patient with no identifiable extraocular septic focus. The patient presented with a dark Hypopyon and markedly elevated intraocular pressure, and the diagnosis was established by culture and histopathologic examination of ocular fluid. Four of the fourteen reported cases of Listeria monocytogenes endophthalmitis also presented with a dark Hypopyon, and all cases had markedly elevated intraocular pressure. The presence of a dark Hypopyon and elevated intraocular pressure may indicate endogenous intraocular infection with Listeria monocytogenes, even in an apparently healthy host.

Bonnie Van Uitert - One of the best experts on this subject based on the ideXlab platform.

  • Hypopyon uveitis in patients with acquired immunodeficiency syndrome treated for systemic mycobacterium avium complex infection with rifabutin
    Archives of Ophthalmology, 1994
    Co-Authors: Bruce R Saran, Albert M Maguire, Charles W Nichols, Ian Frank, Richard W Hertle, Alexander J Brucker, Stephen Goldman, Melissa M Brown, Bonnie Van Uitert
    Abstract:

    Objective: Iridocyclitis has been identified as a dosage-dependent side effect in patients with the acquired immunodeficiency syndrome (AIDS) who are treated for Mycobacterium avium complex (MAC) infection with systemic rifabutin. We reviewed cases of acute Hypopyon uveitis occurring in patients with AIDS to establish whether there was an association. Design: Retrospective case series. Setting: Outpatient clinic and inpatient hospital-based ophthalmology referral practice and infectious disease specialty service. Patients: Seven patients with AIDS, aged 10 to 40 years, presenting with acute unilateral Hypopyon mimicking infectious endophthalmitis. Main Outcome Measures: Findings from complete ophthalmological evaluation and ancillary laboratory testing. Results: At the time of presentation, all seven patients were receiving treatment for MAC infection with rifabutin (dosage range, 300 to 600 mg/d) and clarithromycin. Results of microbiological investigations in five patients were negative. Iridocyclitis became bilateral in all seven patients, and Hypopyon developed in the contralateral eye in five of seven patients. Hypopyon resolved rapidly with intensive topical corticosteroid therapy. Residual inflammation responded to topical corticosteroids with or without reduction of the rifabutin dosage. Conclusions: Concomitant use of rifabutin, clarithromycin, and fluconazole may precipitate Hypopyon uveitis in patients with AIDS being treated for MAC infection.