The Experts below are selected from a list of 39495 Experts worldwide ranked by ideXlab platform
N Iwasaki - One of the best experts on this subject based on the ideXlab platform.
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Net efflux of Cl− during Hypotonic turgor regulation in a brackish water alga Lamprothamnium
Plant Cell and Environment, 1992Co-Authors: Y Okazaki, N IwasakiAbstract:Abstract. Net efflux of Cl− was measured potentiometrically (Ag/AgCl electrode) during turgor regulation which was induced by Hypotonic treatment (Hypotonic turgor regulation) in the alga Lamprothamnium succinctum. The efflux of Cl− reached the peak value (11 μmol m −2s−1) several minutes after the Hypotonic treatment was started and then declined. The efflux of Cl− and inhibition of the cytoplasmic streaming [reflection of an increase in cytoplasmic concentration of free Ca2+([Ca2+]c)] were blocked under a low external concentration of Ca2+ ([Ca2+]e) (0·01 mol m−3) and resumed after raising [Ca2+]e to the normal value (3·9 mol m−3). The decrease in cell-osmotic pressure upon Hypotonic treatment was inhibited by lowering either turgor pressure or [Ca2h]e. The inhibition was reflected in decreases of both the efflux of Cl− and the membrane conductance. Recovery of the cytoplasmic streaming from the inhibition was also accelerated by the same treatments. It is concluded that an increase in turgor pressure is continuously sensed by the cells and that continuous presence of external Ca2+ is necessary for the Hypotonic turgor regulation.
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net efflux of cl during Hypotonic turgor regulation in a brackish water alga lamprothamnium
Plant Cell and Environment, 1992Co-Authors: Y Okazaki, N IwasakiAbstract:Abstract. Net efflux of Cl− was measured potentiometrically (Ag/AgCl electrode) during turgor regulation which was induced by Hypotonic treatment (Hypotonic turgor regulation) in the alga Lamprothamnium succinctum. The efflux of Cl− reached the peak value (11 μmol m −2s−1) several minutes after the Hypotonic treatment was started and then declined. The efflux of Cl− and inhibition of the cytoplasmic streaming [reflection of an increase in cytoplasmic concentration of free Ca2+([Ca2+]c)] were blocked under a low external concentration of Ca2+ ([Ca2+]e) (0·01 mol m−3) and resumed after raising [Ca2+]e to the normal value (3·9 mol m−3). The decrease in cell-osmotic pressure upon Hypotonic treatment was inhibited by lowering either turgor pressure or [Ca2h]e. The inhibition was reflected in decreases of both the efflux of Cl− and the membrane conductance. Recovery of the cytoplasmic streaming from the inhibition was also accelerated by the same treatments. It is concluded that an increase in turgor pressure is continuously sensed by the cells and that continuous presence of external Ca2+ is necessary for the Hypotonic turgor regulation.
Atilim Armagan Demirtas - One of the best experts on this subject based on the ideXlab platform.
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long term outcomes of accelerated corneal cross linking in the treatment of keratoconus comparison of Hypotonic riboflavin solution with standard riboflavin solution
Journal of Refractive Surgery, 2020Co-Authors: Serkan Akkaya, Dondu Melek Ulusoy, Zeynep Duru, Atilim Armagan DemirtasAbstract:PURPOSE: To determine 2-year efficacy of accelerated corneal cross-linking (CXL) in keratoconus treatment using standard riboflavin-dextran or Hypotonic riboflavin solutions. METHODS: Patients undergoing accelerated CXL (epitheliumoff 10 minutes, 9 mW/cm2 protocol) with standard riboflavin solution (48 eyes of 48 patients) or Hypotonic riboflavin solution (43 eyes of 43 patients) were included and followed up for 2 years. Thinnest corneal thickness (TCT), maximum keratometry, and visual acuity were measured and changes from baseline to postoperative 6, 12, and 24 months were compared between the two groups. RESULTS: The preoperative mean TCT with intact epithelium was 472.0 ± 23.9 and 427.5 ± 22.3 µm in the standard riboflavin and Hypotonic riboflavin groups, respectively (P < .001). The decreases in the mean TCT values from baseline to postoperative 6 months were similar between the standard riboflavin (from 472 to 436 µm) and Hypotonic riboflavin (from 427 to 394 µm) groups. This suggested that the Hypotonic riboflavin solution was comparable with the standard riboflavin solution in preserving corneal thickness in keratoconus. There were no significant differences between the study groups regarding the postoperative changes in maximum keratometry or visual acuity. CONCLUSIONS: The efficacy of accelerated CXL with Hypotonic riboflavin solution was comparable to that with the standard riboflavin solution in reducing keratoconus progression in a 2-year follow-up period. [J Refract Surg. 2020;36(2):110-117.].
Y Okazaki - One of the best experts on this subject based on the ideXlab platform.
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Net efflux of Cl− during Hypotonic turgor regulation in a brackish water alga Lamprothamnium
Plant Cell and Environment, 1992Co-Authors: Y Okazaki, N IwasakiAbstract:Abstract. Net efflux of Cl− was measured potentiometrically (Ag/AgCl electrode) during turgor regulation which was induced by Hypotonic treatment (Hypotonic turgor regulation) in the alga Lamprothamnium succinctum. The efflux of Cl− reached the peak value (11 μmol m −2s−1) several minutes after the Hypotonic treatment was started and then declined. The efflux of Cl− and inhibition of the cytoplasmic streaming [reflection of an increase in cytoplasmic concentration of free Ca2+([Ca2+]c)] were blocked under a low external concentration of Ca2+ ([Ca2+]e) (0·01 mol m−3) and resumed after raising [Ca2+]e to the normal value (3·9 mol m−3). The decrease in cell-osmotic pressure upon Hypotonic treatment was inhibited by lowering either turgor pressure or [Ca2h]e. The inhibition was reflected in decreases of both the efflux of Cl− and the membrane conductance. Recovery of the cytoplasmic streaming from the inhibition was also accelerated by the same treatments. It is concluded that an increase in turgor pressure is continuously sensed by the cells and that continuous presence of external Ca2+ is necessary for the Hypotonic turgor regulation.
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net efflux of cl during Hypotonic turgor regulation in a brackish water alga lamprothamnium
Plant Cell and Environment, 1992Co-Authors: Y Okazaki, N IwasakiAbstract:Abstract. Net efflux of Cl− was measured potentiometrically (Ag/AgCl electrode) during turgor regulation which was induced by Hypotonic treatment (Hypotonic turgor regulation) in the alga Lamprothamnium succinctum. The efflux of Cl− reached the peak value (11 μmol m −2s−1) several minutes after the Hypotonic treatment was started and then declined. The efflux of Cl− and inhibition of the cytoplasmic streaming [reflection of an increase in cytoplasmic concentration of free Ca2+([Ca2+]c)] were blocked under a low external concentration of Ca2+ ([Ca2+]e) (0·01 mol m−3) and resumed after raising [Ca2+]e to the normal value (3·9 mol m−3). The decrease in cell-osmotic pressure upon Hypotonic treatment was inhibited by lowering either turgor pressure or [Ca2h]e. The inhibition was reflected in decreases of both the efflux of Cl− and the membrane conductance. Recovery of the cytoplasmic streaming from the inhibition was also accelerated by the same treatments. It is concluded that an increase in turgor pressure is continuously sensed by the cells and that continuous presence of external Ca2+ is necessary for the Hypotonic turgor regulation.
B Zifkin - One of the best experts on this subject based on the ideXlab platform.
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lissencephaly agyria pachygyria clinical findings and serial eeg studies
Developmental Medicine & Child Neurology, 2008Co-Authors: Henri Gastaut, Jean Aicardi, Ch Raybaud, Nicole Pinsard, B ZifkinAbstract:UMMARY Fifteen cases of lissencephaly were studied and the literature reviewed. The authors concluded that the clinical findings of lissencepaly infancy are not-specific, consisting of development delay and hypotonia. While the CT scan establishes the diagnosis, it may also be strongly suggested by an EEG showing ‘major fast dysrhythmia’, characterized by abnormally rapid, very high-voltage activity, predominantly in the alpha and beta frequency bands. Some possible mechanisms for this highly suggestive EEG pattern are proposed. RESUME Lissencephalie (agyrie-pachygyrie): donnees cliniques et etudes EEG en serie Quinze cas de lissencalie ont eteetudies, avec une analyse de la litterature. Les auteurs concluent que les donnees cliniques de la lissencephalie durant l'enfance ne sont pas specifiques, consistent en un retard de developpement et une Hypotonic Tandis que la tomodensitometrie fait le diagnostic, celui-ci peut etre aussi fortement suggere par un EEG montrant “une dysrhytmie majeure rapide”, caracterisee par une activite anormalement rapide, de tres haut voltage, predominant dans les bandes de frequence alpha et beta. Quelques mecanismes possibles pour ces particularites EEG hautement suggestives sont proposes. ZUSAMMENFASSUNG Lissencephalie (Agyrie-Pachygyrie): Klinische Befunde und fortlaufende EEG Untersuchungen 15 Falle mit Lissencephalie wurden untersucht und die Literatur wurde gesichtet. Die Autoren sind der Meinung, das die klinischen Befunde der Lissencephalie im Kindesalter unspezifisch sind, sie bestehen in Entwicklungsverzogerung und Hypotonie. Obwohl die Diagnose durch das Computertomogramm gesichert wird, kann sie doch mit groser Wahrscheinlichkeit durch ein EEG mit vorwiegend hochfrequenter Arrhythmie, charakterisiert durch abnorm schnelle, sehr hohe Amplituden, vorwiegend in den Alpha und Beta Frequenzen, gestellt werden. Es werden einige mogliche Vorgange fur dieses hochst verdachtige EEG Muster diskutiert. RESUMEN Lisencefaiia (agiria-paquigiria): hallazgos cli'nicos y estudios EEG seriados Se estudiaron quince casos de lisencefaiia y se reviso la literatura. Los autores concluyen que los hallazgos clinicos de la lisencefaiia en la lactancia no son especificos y consisten en retraso en el desarrollo e hipotonia. Si bien la TAC establece el diagnostico, puede ser tambien sospechado por el EEG que muestra una disritmia rapida mayor, caracterizada por una actividad anormalmente rapida con voltaje muy alto, con predominio en las bandas de frecuencia alfa y beta. Se proponen algunos posibles mecanismos para este tipo de EEG tan sugestivo.
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LISSENCEPHALY(AGYRIA‐PACHYGYRIA): CLINICAL FINDINGS AND SERIAL EEG STUDIES
Developmental Medicine & Child Neurology, 2008Co-Authors: Henri Gastaut, Jean Aicardi, Ch Raybaud, Nicole Pinsard, B ZifkinAbstract:UMMARY Fifteen cases of lissencephaly were studied and the literature reviewed. The authors concluded that the clinical findings of lissencepaly infancy are not-specific, consisting of development delay and hypotonia. While the CT scan establishes the diagnosis, it may also be strongly suggested by an EEG showing ‘major fast dysrhythmia’, characterized by abnormally rapid, very high-voltage activity, predominantly in the alpha and beta frequency bands. Some possible mechanisms for this highly suggestive EEG pattern are proposed. RESUME Lissencephalie (agyrie-pachygyrie): donnees cliniques et etudes EEG en serie Quinze cas de lissencalie ont eteetudies, avec une analyse de la litterature. Les auteurs concluent que les donnees cliniques de la lissencephalie durant l'enfance ne sont pas specifiques, consistent en un retard de developpement et une Hypotonic Tandis que la tomodensitometrie fait le diagnostic, celui-ci peut etre aussi fortement suggere par un EEG montrant “une dysrhytmie majeure rapide”, caracterisee par une activite anormalement rapide, de tres haut voltage, predominant dans les bandes de frequence alpha et beta. Quelques mecanismes possibles pour ces particularites EEG hautement suggestives sont proposes. ZUSAMMENFASSUNG Lissencephalie (Agyrie-Pachygyrie): Klinische Befunde und fortlaufende EEG Untersuchungen 15 Falle mit Lissencephalie wurden untersucht und die Literatur wurde gesichtet. Die Autoren sind der Meinung, das die klinischen Befunde der Lissencephalie im Kindesalter unspezifisch sind, sie bestehen in Entwicklungsverzogerung und Hypotonie. Obwohl die Diagnose durch das Computertomogramm gesichert wird, kann sie doch mit groser Wahrscheinlichkeit durch ein EEG mit vorwiegend hochfrequenter Arrhythmie, charakterisiert durch abnorm schnelle, sehr hohe Amplituden, vorwiegend in den Alpha und Beta Frequenzen, gestellt werden. Es werden einige mogliche Vorgange fur dieses hochst verdachtige EEG Muster diskutiert. RESUMEN Lisencefaiia (agiria-paquigiria): hallazgos cli'nicos y estudios EEG seriados Se estudiaron quince casos de lisencefaiia y se reviso la literatura. Los autores concluyen que los hallazgos clinicos de la lisencefaiia en la lactancia no son especificos y consisten en retraso en el desarrollo e hipotonia. Si bien la TAC establece el diagnostico, puede ser tambien sospechado por el EEG que muestra una disritmia rapida mayor, caracterizada por una actividad anormalmente rapida con voltaje muy alto, con predominio en las bandas de frecuencia alfa y beta. Se proponen algunos posibles mecanismos para este tipo de EEG tan sugestivo.
Serkan Akkaya - One of the best experts on this subject based on the ideXlab platform.
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long term outcomes of accelerated corneal cross linking in the treatment of keratoconus comparison of Hypotonic riboflavin solution with standard riboflavin solution
Journal of Refractive Surgery, 2020Co-Authors: Serkan Akkaya, Dondu Melek Ulusoy, Zeynep Duru, Atilim Armagan DemirtasAbstract:PURPOSE: To determine 2-year efficacy of accelerated corneal cross-linking (CXL) in keratoconus treatment using standard riboflavin-dextran or Hypotonic riboflavin solutions. METHODS: Patients undergoing accelerated CXL (epitheliumoff 10 minutes, 9 mW/cm2 protocol) with standard riboflavin solution (48 eyes of 48 patients) or Hypotonic riboflavin solution (43 eyes of 43 patients) were included and followed up for 2 years. Thinnest corneal thickness (TCT), maximum keratometry, and visual acuity were measured and changes from baseline to postoperative 6, 12, and 24 months were compared between the two groups. RESULTS: The preoperative mean TCT with intact epithelium was 472.0 ± 23.9 and 427.5 ± 22.3 µm in the standard riboflavin and Hypotonic riboflavin groups, respectively (P < .001). The decreases in the mean TCT values from baseline to postoperative 6 months were similar between the standard riboflavin (from 472 to 436 µm) and Hypotonic riboflavin (from 427 to 394 µm) groups. This suggested that the Hypotonic riboflavin solution was comparable with the standard riboflavin solution in preserving corneal thickness in keratoconus. There were no significant differences between the study groups regarding the postoperative changes in maximum keratometry or visual acuity. CONCLUSIONS: The efficacy of accelerated CXL with Hypotonic riboflavin solution was comparable to that with the standard riboflavin solution in reducing keratoconus progression in a 2-year follow-up period. [J Refract Surg. 2020;36(2):110-117.].
