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Takashi Tokoro - One of the best experts on this subject based on the ideXlab platform.
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Case report : Indocyanine green dye leakage from retinal artery in branch retinal vein occlusion
Japanese Journal of Ophthalmology, 2000Co-Authors: Hiroki Fujita, Soh Futagami, Kyoko Ohno-matsui, Takashi TokoroAbstract:Abstract Little is known about retinal vascular lesions underlying hemorrhage in the acute phase of branch retinal vein occlusion (BRVO). A 64-year-old woman presented with a decrease in visual acuity of ten-day duration in her left eye. At the initial examination, her left fundus showed the typical appearance of BRVO, including retinal bleeding and soft exudates in the lower half of the fundus, after the arteriovenous crossing. Fluorescein Angiography showed no detail in the retinal vessels, which were occluded by retinal bleeding. However, in the early phase of indocyanine green (ICG) Angiography, ICG dye leaked from the retinal artery at a point proximal to the first bifurcation. In the late phase of ICG Angiography, the dye pooled along the retinal artery in a fusiform fashion. One year after laser photocoagulation was performed in the area of the BRVO, ICG dye leakage from the retinal artery had completely disappeared. These findings suggest that the changes in the retina detected by ICG Angiography may have been associated with the onset of BRVO. In patients with acute BRVO, ICG Angiography may be used to evaluate retinal arterial lesions covered by hemorrhage and provide useful information.
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zinn haller arterial ring observed by ICG Angiography in high myopia
British Journal of Ophthalmology, 1998Co-Authors: Kyoko Ohnomatsui, Soh Futagami, Satoshi Yamashita, Takashi TokoroAbstract:AIMS To delineate the entire Zinn–Haller arterial ring angiographically in vivo. METHODS 382 highly myopic eyes (210 patients) with refractive errors greater than −8.25 D were examined using indocyanine green (ICG) videoAngiography. A control group of 80 eyes (40 patients) had refractive errors within plano +/− 3 D. RESULTS The Zinn–Haller ring was visible in 206 of 382 highly myopic eyes (53.9%) by ICG Angiography. Although only a part of the Zinn–Haller ring was visible in 162 of 206 eyes, in the remaining 44 eyes it was observed almost completely around the optic nerve head. No anastomotic channels between lateral and medial short posterior ciliary arteries were filled by ICG Angiography. In 22 of the 44 eyes (50.0%) the Zinn–Haller ring was supplied by branches of the lateral and medial short posterior ciliary arteries; in seven eyes, it was supplied only by the lateral short posterior ciliary artery; and in seven eyes, it was supplied only by the medial short posterior ciliary artery. In none of the control subjects was the Zinn–Haller ring visible by ICG Angiography. CONCLUSIONS The Zinn–Haller ring observed by ICG Angiography was not a complete collateral circle between lateral and medial posterior ciliary arteries. Also, the patterns in supply vessels to the Zinn–Haller ring varied. ICG Angiography made possible the detailed observation of the Zinn–Haller ring in human eyes in vivo.
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Zinn–Haller arterial ring observed by ICG Angiography in high myopia
British Journal of Ophthalmology, 1998Co-Authors: Kyoko Ohno-matsui, Soh Futagami, Satoshi Yamashita, Takashi TokoroAbstract:AIMS To delineate the entire Zinn–Haller arterial ring angiographically in vivo. METHODS 382 highly myopic eyes (210 patients) with refractive errors greater than −8.25 D were examined using indocyanine green (ICG) videoAngiography. A control group of 80 eyes (40 patients) had refractive errors within plano +/− 3 D. RESULTS The Zinn–Haller ring was visible in 206 of 382 highly myopic eyes (53.9%) by ICG Angiography. Although only a part of the Zinn–Haller ring was visible in 162 of 206 eyes, in the remaining 44 eyes it was observed almost completely around the optic nerve head. No anastomotic channels between lateral and medial short posterior ciliary arteries were filled by ICG Angiography. In 22 of the 44 eyes (50.0%) the Zinn–Haller ring was supplied by branches of the lateral and medial short posterior ciliary arteries; in seven eyes, it was supplied only by the lateral short posterior ciliary artery; and in seven eyes, it was supplied only by the medial short posterior ciliary artery. In none of the control subjects was the Zinn–Haller ring visible by ICG Angiography. CONCLUSIONS The Zinn–Haller ring observed by ICG Angiography was not a complete collateral circle between lateral and medial posterior ciliary arteries. Also, the patterns in supply vessels to the Zinn–Haller ring varied. ICG Angiography made possible the detailed observation of the Zinn–Haller ring in human eyes in vivo.
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Indocyanine Green Angiographic Findings of Lacquer Cracks in Pathologic Myopia
Japanese Journal of Ophthalmology, 1998Co-Authors: Kyoko Ohno-matsui, Naoto Morishima, Takashi TokoroAbstract:Abstract Lacquer cracks are thought to represent healed mechanical breaks in the retinal pigment epithelium, Bruch’s membrane, and choriocapillaris complex. In this study, we analyzed the indocyanine green (ICG) angiographic features of lacquer cracks and compared them with findings using fluorescein Angiography. Complete ophthalmologic examinations, fluorescein Angiography, and ICG Angiography were performed in 29 consecutive patients (37 eyes) with lacquer cracks. Fluorescein angiograms of the cracks revealed linear hyperfluorescence in all 37 eyes. Using ICG Angiography, we observed linear hypofluorescence in all 37 eyes. In 15 of 37 eyes, the length of the hypofluorescent lesion detected by ICG Angiography was longer than the hyperfluorescent lesion observed by fluorescein Angiography. In 17 of 37 eyes, more lacquer cracks were observed by ICG Angiography than by fluorescein Angiography. These findings indicate that ICG Angiography can detect the development of the lesion more precisely, and may provide useful information for diagnosing pathologic myopia.
Shaye I Moskowitz - One of the best experts on this subject based on the ideXlab platform.
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intraoperative indocyanine green Angiography as a substitute for conventional Angiography in the surgical management of spinal dural arteriovenous fistulae
Journal of NeuroInterventional Surgery, 2011Co-Authors: Alejandro M Spiotta, Mark Bain, Shaye I MoskowitzAbstract:Introduction Spinal dural arteriovenous fistula (dAVF) is the most common vascular malformation of the spinal cord. We performed a prospective observational study of patients with spinal dAVF who were treated by microsurgical obliteration to determine whether intraoperative indocyanine green (ICG) angiograph provides supplemental flow-related data that change the surgical plan and whether the resolution afforded by ICG Angiography may substitute for conventional postoperative spinal Angiography. Methods Five patients over a 6-month period were included who were treated surgically with intraoperative intravenous administration of ICG. Direct microsurgical exploration was employed to identify the intradural fistulous connection and intravenous ICG was then injected to verify the identification of the lesion. Repeat ICG Angiography was performed after the fistula had been obliterated using bipolar electrocautery. All patients underwent a spinal angiogram on postoperative day 1. Results In four patients, ICG Angiography correlated reliably with preoperative catheter Angiography and intraoperative direct visualization. For these cases, the ICG angiogram did not alter the surgical plan, and the fistulous connection was identified and successfully treated surgically. In a fifth case, exploratory surgery for a fistula was not convincing and the information provided by intraoperative ICG Angiography guided management to proceed with a cord biopsy. Conclusion ICG Angiography in the setting of surgical management of spinal dAVF is a simple and effective technique for intraoperative confirmation of the relevant lesion. Postresection ICG Angiography reliably demonstrated technical success and may replace formal postoperative catheter Angiography. Additionally, the surgical plan may be modified based on ICG Angiography.
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p 003 intraoperative indocyanine green Angiography to verify the eradication of spinal dural arteriovenous fistulae as a substitute for conventional Angiography
Journal of NeuroInterventional Surgery, 2010Co-Authors: Alejandro M Spiotta, Mark Bain, Muhammad S Hussain, Thinesh Sivapatham, Shaye I MoskowitzAbstract:Introduction Spinal dural arteriovenous fistulas (dAVF) are the most common vascular malformations of the spinal cord. The arterialization of the recipient radicular vein results in venous hypertension and cord edema. Without treatment, symptoms may progress to myelopathy, sensory deficits, paraplegia, bowel and urinary incontinence, and potentially venous infarction of the cord. Successful treatment of these lesions can halt symptom progression and result in significant functional recovery in many patients. To achieve obliteration of a spinal dAVF, the shunt site has to be targeted either by microsurgical clipping or by superselective embolization via an endovascular approach. The introduction of indocyanine green (ICG) into the operating room for use by surgeons performing a variety of neurovascular procedures holds promise as a useful adjunct. Employing this method, the operating field is illuminated by near infrared excitation light and ICG is injected intravenously. The intravenous fluorescence is imaged instantly with a video camera integrated into the microscope allowing differentiation between arterial, capillary and venous phases. ICG Angiography provides a minimally invasive, quick, safe and reliable method of imaging the vasculature within the operative field. Methods We performed a prospective observational study of patients with spinal dAVF that were treated by microsurgical obliteration to determine if ICG Angiography: (1) provided supplemental flow related data that changed the surgical plan as it has been found useful for other neurovascular procedures; and (2) if the fidelity and resolution afforded by ICG Angiography intraoperatively may substitute for a conventional postoperative selective spinal angiogram. Results Four patients over a 6 month period were identified who were treated surgically with intraoperative confirmation with intravenous use of ICG. In all four cases, intraoperative radiographic identification of the level of the lesion, as determined by Angiography, was achieved and led to a laminectomy and durotomy being performed at the correct site. In all cases, direct visual identification of the fistulous connection in close proximity to the exiting nerve root was readily obtained on intradural inspection. Initial ICG Angiography confirmed the fistula but in none of the cases did it change the surgical plan. Following treatment of the lesion, ICG Angiography was repeated. Confirmation of the eradication of the fistula was obtained in all cases with normal dye transit into pial veins. There was no residual filling of the fistulous vein in any of the cases and the findings from ICG Angiography did not change the ultimate surgical management. In all four cases, conventional postoperative angiogram confirmed complete treatment of the dAVF. All patients demonstrated subjective and objective improvements in their lower extremity motor and sensory function. Conclusions ICG Angiography in the setting of surgical management of spinal dural fistula is a simple and effective technique for intraoperative confirmation of the relevant lesion. Additionally, post-resection ICG Angiography reliably demonstrated technical success and may replace formal postoperative catheter Angiography. Although not needed in our cases, the surgical plan may be modified based on ICG Angiography should the lesion be more complex.
Alejandro M Spiotta - One of the best experts on this subject based on the ideXlab platform.
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intraoperative indocyanine green Angiography as a substitute for conventional Angiography in the surgical management of spinal dural arteriovenous fistulae
Journal of NeuroInterventional Surgery, 2011Co-Authors: Alejandro M Spiotta, Mark Bain, Shaye I MoskowitzAbstract:Introduction Spinal dural arteriovenous fistula (dAVF) is the most common vascular malformation of the spinal cord. We performed a prospective observational study of patients with spinal dAVF who were treated by microsurgical obliteration to determine whether intraoperative indocyanine green (ICG) angiograph provides supplemental flow-related data that change the surgical plan and whether the resolution afforded by ICG Angiography may substitute for conventional postoperative spinal Angiography. Methods Five patients over a 6-month period were included who were treated surgically with intraoperative intravenous administration of ICG. Direct microsurgical exploration was employed to identify the intradural fistulous connection and intravenous ICG was then injected to verify the identification of the lesion. Repeat ICG Angiography was performed after the fistula had been obliterated using bipolar electrocautery. All patients underwent a spinal angiogram on postoperative day 1. Results In four patients, ICG Angiography correlated reliably with preoperative catheter Angiography and intraoperative direct visualization. For these cases, the ICG angiogram did not alter the surgical plan, and the fistulous connection was identified and successfully treated surgically. In a fifth case, exploratory surgery for a fistula was not convincing and the information provided by intraoperative ICG Angiography guided management to proceed with a cord biopsy. Conclusion ICG Angiography in the setting of surgical management of spinal dAVF is a simple and effective technique for intraoperative confirmation of the relevant lesion. Postresection ICG Angiography reliably demonstrated technical success and may replace formal postoperative catheter Angiography. Additionally, the surgical plan may be modified based on ICG Angiography.
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p 003 intraoperative indocyanine green Angiography to verify the eradication of spinal dural arteriovenous fistulae as a substitute for conventional Angiography
Journal of NeuroInterventional Surgery, 2010Co-Authors: Alejandro M Spiotta, Mark Bain, Muhammad S Hussain, Thinesh Sivapatham, Shaye I MoskowitzAbstract:Introduction Spinal dural arteriovenous fistulas (dAVF) are the most common vascular malformations of the spinal cord. The arterialization of the recipient radicular vein results in venous hypertension and cord edema. Without treatment, symptoms may progress to myelopathy, sensory deficits, paraplegia, bowel and urinary incontinence, and potentially venous infarction of the cord. Successful treatment of these lesions can halt symptom progression and result in significant functional recovery in many patients. To achieve obliteration of a spinal dAVF, the shunt site has to be targeted either by microsurgical clipping or by superselective embolization via an endovascular approach. The introduction of indocyanine green (ICG) into the operating room for use by surgeons performing a variety of neurovascular procedures holds promise as a useful adjunct. Employing this method, the operating field is illuminated by near infrared excitation light and ICG is injected intravenously. The intravenous fluorescence is imaged instantly with a video camera integrated into the microscope allowing differentiation between arterial, capillary and venous phases. ICG Angiography provides a minimally invasive, quick, safe and reliable method of imaging the vasculature within the operative field. Methods We performed a prospective observational study of patients with spinal dAVF that were treated by microsurgical obliteration to determine if ICG Angiography: (1) provided supplemental flow related data that changed the surgical plan as it has been found useful for other neurovascular procedures; and (2) if the fidelity and resolution afforded by ICG Angiography intraoperatively may substitute for a conventional postoperative selective spinal angiogram. Results Four patients over a 6 month period were identified who were treated surgically with intraoperative confirmation with intravenous use of ICG. In all four cases, intraoperative radiographic identification of the level of the lesion, as determined by Angiography, was achieved and led to a laminectomy and durotomy being performed at the correct site. In all cases, direct visual identification of the fistulous connection in close proximity to the exiting nerve root was readily obtained on intradural inspection. Initial ICG Angiography confirmed the fistula but in none of the cases did it change the surgical plan. Following treatment of the lesion, ICG Angiography was repeated. Confirmation of the eradication of the fistula was obtained in all cases with normal dye transit into pial veins. There was no residual filling of the fistulous vein in any of the cases and the findings from ICG Angiography did not change the ultimate surgical management. In all four cases, conventional postoperative angiogram confirmed complete treatment of the dAVF. All patients demonstrated subjective and objective improvements in their lower extremity motor and sensory function. Conclusions ICG Angiography in the setting of surgical management of spinal dural fistula is a simple and effective technique for intraoperative confirmation of the relevant lesion. Additionally, post-resection ICG Angiography reliably demonstrated technical success and may replace formal postoperative catheter Angiography. Although not needed in our cases, the surgical plan may be modified based on ICG Angiography should the lesion be more complex.
Kyoko Ohnomatsui - One of the best experts on this subject based on the ideXlab platform.
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choroidal vascular lesions identified by ICG Angiography in a case of familial amyloidotic polyneuropathy
Japanese Journal of Ophthalmology, 2003Co-Authors: Ariko Kojima, Kyoko Ohnomatsui, Tamaki Mitsuhashi, Shizuko Ichinose, Tetsuo Nemoto, Takumi Akashi, Yoshinobu Eishi, Shuichi Ikeda, Akira Hirose, Manabu MochizukiAbstract:Abstract Background: To describe a patient with familial amyloidotic polyneuropathy (FAP) whose choroidal vascular lesions were demonstrated dynamically with the use of indocyanine green (ICG) Angiography. Case: A 59-year-old man complained of blurred vision due to vitreal amyloidosis in both eyes. Fundus examination after pars plana vitrectomy showed multiple retinal hemorrhages. Observations: ICG Angiography performed after vitrectomy clearly delineated multiple sites of hyperfluorescence indicating tissue staining alongside the major choroidal veins in the lower fundus of his left eye. ICG hyperfluorescence was more evident in the late angiographic phase. Fundus examination and fluorescein Angiography revealed no abnormal findings at the corresponding sites of ICG dye leakage. Conclusions: Choroidal vascular lesions in eyes with FAP were demonstrated in vivo using ICG Angiography for the first time. ICG Angiography may be very beneficial to evaluate occult choroidal involvement in patients with FAP.
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zinn haller arterial ring observed by ICG Angiography in high myopia
British Journal of Ophthalmology, 1998Co-Authors: Kyoko Ohnomatsui, Soh Futagami, Satoshi Yamashita, Takashi TokoroAbstract:AIMS To delineate the entire Zinn–Haller arterial ring angiographically in vivo. METHODS 382 highly myopic eyes (210 patients) with refractive errors greater than −8.25 D were examined using indocyanine green (ICG) videoAngiography. A control group of 80 eyes (40 patients) had refractive errors within plano +/− 3 D. RESULTS The Zinn–Haller ring was visible in 206 of 382 highly myopic eyes (53.9%) by ICG Angiography. Although only a part of the Zinn–Haller ring was visible in 162 of 206 eyes, in the remaining 44 eyes it was observed almost completely around the optic nerve head. No anastomotic channels between lateral and medial short posterior ciliary arteries were filled by ICG Angiography. In 22 of the 44 eyes (50.0%) the Zinn–Haller ring was supplied by branches of the lateral and medial short posterior ciliary arteries; in seven eyes, it was supplied only by the lateral short posterior ciliary artery; and in seven eyes, it was supplied only by the medial short posterior ciliary artery. In none of the control subjects was the Zinn–Haller ring visible by ICG Angiography. CONCLUSIONS The Zinn–Haller ring observed by ICG Angiography was not a complete collateral circle between lateral and medial posterior ciliary arteries. Also, the patterns in supply vessels to the Zinn–Haller ring varied. ICG Angiography made possible the detailed observation of the Zinn–Haller ring in human eyes in vivo.
Soh Futagami - One of the best experts on this subject based on the ideXlab platform.
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Case report : Indocyanine green dye leakage from retinal artery in branch retinal vein occlusion
Japanese Journal of Ophthalmology, 2000Co-Authors: Hiroki Fujita, Soh Futagami, Kyoko Ohno-matsui, Takashi TokoroAbstract:Abstract Little is known about retinal vascular lesions underlying hemorrhage in the acute phase of branch retinal vein occlusion (BRVO). A 64-year-old woman presented with a decrease in visual acuity of ten-day duration in her left eye. At the initial examination, her left fundus showed the typical appearance of BRVO, including retinal bleeding and soft exudates in the lower half of the fundus, after the arteriovenous crossing. Fluorescein Angiography showed no detail in the retinal vessels, which were occluded by retinal bleeding. However, in the early phase of indocyanine green (ICG) Angiography, ICG dye leaked from the retinal artery at a point proximal to the first bifurcation. In the late phase of ICG Angiography, the dye pooled along the retinal artery in a fusiform fashion. One year after laser photocoagulation was performed in the area of the BRVO, ICG dye leakage from the retinal artery had completely disappeared. These findings suggest that the changes in the retina detected by ICG Angiography may have been associated with the onset of BRVO. In patients with acute BRVO, ICG Angiography may be used to evaluate retinal arterial lesions covered by hemorrhage and provide useful information.
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zinn haller arterial ring observed by ICG Angiography in high myopia
British Journal of Ophthalmology, 1998Co-Authors: Kyoko Ohnomatsui, Soh Futagami, Satoshi Yamashita, Takashi TokoroAbstract:AIMS To delineate the entire Zinn–Haller arterial ring angiographically in vivo. METHODS 382 highly myopic eyes (210 patients) with refractive errors greater than −8.25 D were examined using indocyanine green (ICG) videoAngiography. A control group of 80 eyes (40 patients) had refractive errors within plano +/− 3 D. RESULTS The Zinn–Haller ring was visible in 206 of 382 highly myopic eyes (53.9%) by ICG Angiography. Although only a part of the Zinn–Haller ring was visible in 162 of 206 eyes, in the remaining 44 eyes it was observed almost completely around the optic nerve head. No anastomotic channels between lateral and medial short posterior ciliary arteries were filled by ICG Angiography. In 22 of the 44 eyes (50.0%) the Zinn–Haller ring was supplied by branches of the lateral and medial short posterior ciliary arteries; in seven eyes, it was supplied only by the lateral short posterior ciliary artery; and in seven eyes, it was supplied only by the medial short posterior ciliary artery. In none of the control subjects was the Zinn–Haller ring visible by ICG Angiography. CONCLUSIONS The Zinn–Haller ring observed by ICG Angiography was not a complete collateral circle between lateral and medial posterior ciliary arteries. Also, the patterns in supply vessels to the Zinn–Haller ring varied. ICG Angiography made possible the detailed observation of the Zinn–Haller ring in human eyes in vivo.
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Zinn–Haller arterial ring observed by ICG Angiography in high myopia
British Journal of Ophthalmology, 1998Co-Authors: Kyoko Ohno-matsui, Soh Futagami, Satoshi Yamashita, Takashi TokoroAbstract:AIMS To delineate the entire Zinn–Haller arterial ring angiographically in vivo. METHODS 382 highly myopic eyes (210 patients) with refractive errors greater than −8.25 D were examined using indocyanine green (ICG) videoAngiography. A control group of 80 eyes (40 patients) had refractive errors within plano +/− 3 D. RESULTS The Zinn–Haller ring was visible in 206 of 382 highly myopic eyes (53.9%) by ICG Angiography. Although only a part of the Zinn–Haller ring was visible in 162 of 206 eyes, in the remaining 44 eyes it was observed almost completely around the optic nerve head. No anastomotic channels between lateral and medial short posterior ciliary arteries were filled by ICG Angiography. In 22 of the 44 eyes (50.0%) the Zinn–Haller ring was supplied by branches of the lateral and medial short posterior ciliary arteries; in seven eyes, it was supplied only by the lateral short posterior ciliary artery; and in seven eyes, it was supplied only by the medial short posterior ciliary artery. In none of the control subjects was the Zinn–Haller ring visible by ICG Angiography. CONCLUSIONS The Zinn–Haller ring observed by ICG Angiography was not a complete collateral circle between lateral and medial posterior ciliary arteries. Also, the patterns in supply vessels to the Zinn–Haller ring varied. ICG Angiography made possible the detailed observation of the Zinn–Haller ring in human eyes in vivo.
