The Experts below are selected from a list of 43251 Experts worldwide ranked by ideXlab platform

Katsumi Ishii - One of the best experts on this subject based on the ideXlab platform.

  • the mean transit time and functional Image in asialoglycoprotein receptor scintigraphy a novel modality for evaluating the regional dynamic function of hepatocytes
    The Journal of Nuclear Medicine, 2002
    Co-Authors: Yasuharu Ohno, Haruo Ishida, Akira Hayashi, Shoichiro Kamagata, Seiichi Hirobe, Katsumi Ishii
    Abstract:

    In this study, we attempted to evaluate the regional dynamic function of hepatocytes by introducing unique parameters in 99mTc-diethylenetriaminepentaacetic acid-galactosyl-human serum albumin 99mTc-GSA) scintigraphy. 99mTc-GSA scintigraphy provides valuable information for the receptor population density. However, the conventional indices are the results of the analyses of 2 fixed points and, as a result, it is not possible to accurately estimate the regional dynamic function. Methods: We performed 99mTc-GSA scintigraphy 100 times on a total of 54 pediatric patients. The average age at examination was 7.4 ± 5.8 y. Ninety-one of the 100 scintigraphy cases were available for this study. We converted the time-activity Curve for the liver of 99mTc-GSA to a horizontal mirror Image Curve, and, on the basis of the height-over-area method, calculated the mean transit time (MTT) in each pixel and depicted the functional Image as unique parameters, which were thus compared with the conventional indices. For these parameters, we used the time-activity Curve for only the liver. Results: The whole liver MTT showed a significant correlation with both the clearance (y = 590.3x + 10.3; r = 0.51; P

Yasuharu Ohno - One of the best experts on this subject based on the ideXlab platform.

  • the mean transit time and functional Image in asialoglycoprotein receptor scintigraphy a novel modality for evaluating the regional dynamic function of hepatocytes
    The Journal of Nuclear Medicine, 2002
    Co-Authors: Yasuharu Ohno, Haruo Ishida, Akira Hayashi, Shoichiro Kamagata, Seiichi Hirobe, Katsumi Ishii
    Abstract:

    In this study, we attempted to evaluate the regional dynamic function of hepatocytes by introducing unique parameters in 99mTc-diethylenetriaminepentaacetic acid-galactosyl-human serum albumin 99mTc-GSA) scintigraphy. 99mTc-GSA scintigraphy provides valuable information for the receptor population density. However, the conventional indices are the results of the analyses of 2 fixed points and, as a result, it is not possible to accurately estimate the regional dynamic function. Methods: We performed 99mTc-GSA scintigraphy 100 times on a total of 54 pediatric patients. The average age at examination was 7.4 ± 5.8 y. Ninety-one of the 100 scintigraphy cases were available for this study. We converted the time-activity Curve for the liver of 99mTc-GSA to a horizontal mirror Image Curve, and, on the basis of the height-over-area method, calculated the mean transit time (MTT) in each pixel and depicted the functional Image as unique parameters, which were thus compared with the conventional indices. For these parameters, we used the time-activity Curve for only the liver. Results: The whole liver MTT showed a significant correlation with both the clearance (y = 590.3x + 10.3; r = 0.51; P

Shoichiro Kamagata - One of the best experts on this subject based on the ideXlab platform.

  • the mean transit time and functional Image in asialoglycoprotein receptor scintigraphy a novel modality for evaluating the regional dynamic function of hepatocytes
    The Journal of Nuclear Medicine, 2002
    Co-Authors: Yasuharu Ohno, Haruo Ishida, Akira Hayashi, Shoichiro Kamagata, Seiichi Hirobe, Katsumi Ishii
    Abstract:

    In this study, we attempted to evaluate the regional dynamic function of hepatocytes by introducing unique parameters in 99mTc-diethylenetriaminepentaacetic acid-galactosyl-human serum albumin 99mTc-GSA) scintigraphy. 99mTc-GSA scintigraphy provides valuable information for the receptor population density. However, the conventional indices are the results of the analyses of 2 fixed points and, as a result, it is not possible to accurately estimate the regional dynamic function. Methods: We performed 99mTc-GSA scintigraphy 100 times on a total of 54 pediatric patients. The average age at examination was 7.4 ± 5.8 y. Ninety-one of the 100 scintigraphy cases were available for this study. We converted the time-activity Curve for the liver of 99mTc-GSA to a horizontal mirror Image Curve, and, on the basis of the height-over-area method, calculated the mean transit time (MTT) in each pixel and depicted the functional Image as unique parameters, which were thus compared with the conventional indices. For these parameters, we used the time-activity Curve for only the liver. Results: The whole liver MTT showed a significant correlation with both the clearance (y = 590.3x + 10.3; r = 0.51; P

Haruo Ishida - One of the best experts on this subject based on the ideXlab platform.

  • the mean transit time and functional Image in asialoglycoprotein receptor scintigraphy a novel modality for evaluating the regional dynamic function of hepatocytes
    The Journal of Nuclear Medicine, 2002
    Co-Authors: Yasuharu Ohno, Haruo Ishida, Akira Hayashi, Shoichiro Kamagata, Seiichi Hirobe, Katsumi Ishii
    Abstract:

    In this study, we attempted to evaluate the regional dynamic function of hepatocytes by introducing unique parameters in 99mTc-diethylenetriaminepentaacetic acid-galactosyl-human serum albumin 99mTc-GSA) scintigraphy. 99mTc-GSA scintigraphy provides valuable information for the receptor population density. However, the conventional indices are the results of the analyses of 2 fixed points and, as a result, it is not possible to accurately estimate the regional dynamic function. Methods: We performed 99mTc-GSA scintigraphy 100 times on a total of 54 pediatric patients. The average age at examination was 7.4 ± 5.8 y. Ninety-one of the 100 scintigraphy cases were available for this study. We converted the time-activity Curve for the liver of 99mTc-GSA to a horizontal mirror Image Curve, and, on the basis of the height-over-area method, calculated the mean transit time (MTT) in each pixel and depicted the functional Image as unique parameters, which were thus compared with the conventional indices. For these parameters, we used the time-activity Curve for only the liver. Results: The whole liver MTT showed a significant correlation with both the clearance (y = 590.3x + 10.3; r = 0.51; P

Seiichi Hirobe - One of the best experts on this subject based on the ideXlab platform.

  • the mean transit time and functional Image in asialoglycoprotein receptor scintigraphy a novel modality for evaluating the regional dynamic function of hepatocytes
    The Journal of Nuclear Medicine, 2002
    Co-Authors: Yasuharu Ohno, Haruo Ishida, Akira Hayashi, Shoichiro Kamagata, Seiichi Hirobe, Katsumi Ishii
    Abstract:

    In this study, we attempted to evaluate the regional dynamic function of hepatocytes by introducing unique parameters in 99mTc-diethylenetriaminepentaacetic acid-galactosyl-human serum albumin 99mTc-GSA) scintigraphy. 99mTc-GSA scintigraphy provides valuable information for the receptor population density. However, the conventional indices are the results of the analyses of 2 fixed points and, as a result, it is not possible to accurately estimate the regional dynamic function. Methods: We performed 99mTc-GSA scintigraphy 100 times on a total of 54 pediatric patients. The average age at examination was 7.4 ± 5.8 y. Ninety-one of the 100 scintigraphy cases were available for this study. We converted the time-activity Curve for the liver of 99mTc-GSA to a horizontal mirror Image Curve, and, on the basis of the height-over-area method, calculated the mean transit time (MTT) in each pixel and depicted the functional Image as unique parameters, which were thus compared with the conventional indices. For these parameters, we used the time-activity Curve for only the liver. Results: The whole liver MTT showed a significant correlation with both the clearance (y = 590.3x + 10.3; r = 0.51; P