The Experts below are selected from a list of 9 Experts worldwide ranked by ideXlab platform
Valerio Bertolasi - One of the best experts on this subject based on the ideXlab platform.
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4-(E)-2-[3-(3-[(E)-2-(4-cyanophenyl)-1-diazenyl]perhydrobenzo[d]imidazol-1-ylmethyl)perhydrobenzo[d]imidazol-1-yl]-1-diazenylbenzonitrile: X-ray crystal structure
Journal of Chemical Crystallography, 2004Co-Authors: Julie F. Glister, Keith Vaughan, Valerio BertolasiAbstract:4-( E )-2-[3-(3-[( E )-2-(4-Cyanophenyl)-1-diazenyl]perhydrobenzo[ d ]imidazol-1-ylmethyl) perhydrobenzo[ d ]imidazol-1-yl]-1-diazenylbenzonitrile ( 1 ) has been synthesized by reac- tion of p -cyanobenzene diazonium chloride with a mixture of formaldehyde and trans -1,2-cyclohexanediamine. The crystal structure has been determined by single crystal X-ray diffraction analysis. The bis-triazene ( 1 ) does not adopt a folded conformation, unlike previously studied ethylenediamine analogues, and there is no indication of π-stacking in the crystal packing. The dominant interaction between molecules is the van der Waal's attraction between cyclohexane rings. This result establishes the structure of the product of this diazonium coupling reaction as the 1-(1-imidazolidinylmethyl)Imidazolidine Derivative and not the alternate tetraazabicyclo[4.4.1]undecane Derivative. Crystal data: 1 C_29H_34N_10, orthorhombic, space group Pbca , a = 17.946(1), b = 13.106(1), c = 24.108(1) Å, V = 5670.6(3) Å^3, for Z = 8.
Manal M Elshahawi - One of the best experts on this subject based on the ideXlab platform.
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synthesis of 1 2 4 triazoles imidazoles pyrimidines quinazolines 1 3 5 triazines and 1 3 thiazines from 3 oxo 5 6 diphenyl 2 3 dihydro pyridazine 4 carbonyl isothiocyanate
Journal of Chemical Research-s, 2009Co-Authors: Magdy M Hemdan, Manal M ElshahawiAbstract:3-Oxo-5,6-diphenyl-2,3-dihydropyridazine-4-carbonyl isothiocyanate (1) was reacted with hydrazine hydrate, or phenyl hydrazine, to give 1,2,4-triazole Derivatives in a one pot-reaction. However, reaction of 1 with benzoyl hydrazine afforded thiourea Derivative that was cyclised to a differently substituted 1,2,4-triazole. Ethyl glycinate reacted with isothiocyanate 1 to give an adduct that was cyclised to Imidazolidine Derivative. Reaction of 1 with o-aminophenol, o-phenylenediamine or o-aminothiophenol afforded benzoxazole, benzimidazole or benzothiazole Derivatives respectively. Reaction of 1 with thioglycolic acid gave 1,3-thiazine Derivative, however, when 1 was treated with anthranilic acid a thiourea Derivative was obtained which cyclised to a quinazoline Derivative. Reaction of 1 with 2-cyanoacetamide or guanidine HCI yielded pyrimidine or triazine Derivatives respectively. The structures of all compounds were confirmed by their micro analytical and spectral data.
Julie F. Glister - One of the best experts on this subject based on the ideXlab platform.
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4-(E)-2-[3-(3-[(E)-2-(4-cyanophenyl)-1-diazenyl]perhydrobenzo[d]imidazol-1-ylmethyl)perhydrobenzo[d]imidazol-1-yl]-1-diazenylbenzonitrile: X-ray crystal structure
Journal of Chemical Crystallography, 2004Co-Authors: Julie F. Glister, Keith Vaughan, Valerio BertolasiAbstract:4-( E )-2-[3-(3-[( E )-2-(4-Cyanophenyl)-1-diazenyl]perhydrobenzo[ d ]imidazol-1-ylmethyl) perhydrobenzo[ d ]imidazol-1-yl]-1-diazenylbenzonitrile ( 1 ) has been synthesized by reac- tion of p -cyanobenzene diazonium chloride with a mixture of formaldehyde and trans -1,2-cyclohexanediamine. The crystal structure has been determined by single crystal X-ray diffraction analysis. The bis-triazene ( 1 ) does not adopt a folded conformation, unlike previously studied ethylenediamine analogues, and there is no indication of π-stacking in the crystal packing. The dominant interaction between molecules is the van der Waal's attraction between cyclohexane rings. This result establishes the structure of the product of this diazonium coupling reaction as the 1-(1-imidazolidinylmethyl)Imidazolidine Derivative and not the alternate tetraazabicyclo[4.4.1]undecane Derivative. Crystal data: 1 C_29H_34N_10, orthorhombic, space group Pbca , a = 17.946(1), b = 13.106(1), c = 24.108(1) Å, V = 5670.6(3) Å^3, for Z = 8.
Magdy M Hemdan - One of the best experts on this subject based on the ideXlab platform.
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synthesis of 1 2 4 triazoles imidazoles pyrimidines quinazolines 1 3 5 triazines and 1 3 thiazines from 3 oxo 5 6 diphenyl 2 3 dihydro pyridazine 4 carbonyl isothiocyanate
Journal of Chemical Research-s, 2009Co-Authors: Magdy M Hemdan, Manal M ElshahawiAbstract:3-Oxo-5,6-diphenyl-2,3-dihydropyridazine-4-carbonyl isothiocyanate (1) was reacted with hydrazine hydrate, or phenyl hydrazine, to give 1,2,4-triazole Derivatives in a one pot-reaction. However, reaction of 1 with benzoyl hydrazine afforded thiourea Derivative that was cyclised to a differently substituted 1,2,4-triazole. Ethyl glycinate reacted with isothiocyanate 1 to give an adduct that was cyclised to Imidazolidine Derivative. Reaction of 1 with o-aminophenol, o-phenylenediamine or o-aminothiophenol afforded benzoxazole, benzimidazole or benzothiazole Derivatives respectively. Reaction of 1 with thioglycolic acid gave 1,3-thiazine Derivative, however, when 1 was treated with anthranilic acid a thiourea Derivative was obtained which cyclised to a quinazoline Derivative. Reaction of 1 with 2-cyanoacetamide or guanidine HCI yielded pyrimidine or triazine Derivatives respectively. The structures of all compounds were confirmed by their micro analytical and spectral data.
Keith Vaughan - One of the best experts on this subject based on the ideXlab platform.
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4-(E)-2-[3-(3-[(E)-2-(4-cyanophenyl)-1-diazenyl]perhydrobenzo[d]imidazol-1-ylmethyl)perhydrobenzo[d]imidazol-1-yl]-1-diazenylbenzonitrile: X-ray crystal structure
Journal of Chemical Crystallography, 2004Co-Authors: Julie F. Glister, Keith Vaughan, Valerio BertolasiAbstract:4-( E )-2-[3-(3-[( E )-2-(4-Cyanophenyl)-1-diazenyl]perhydrobenzo[ d ]imidazol-1-ylmethyl) perhydrobenzo[ d ]imidazol-1-yl]-1-diazenylbenzonitrile ( 1 ) has been synthesized by reac- tion of p -cyanobenzene diazonium chloride with a mixture of formaldehyde and trans -1,2-cyclohexanediamine. The crystal structure has been determined by single crystal X-ray diffraction analysis. The bis-triazene ( 1 ) does not adopt a folded conformation, unlike previously studied ethylenediamine analogues, and there is no indication of π-stacking in the crystal packing. The dominant interaction between molecules is the van der Waal's attraction between cyclohexane rings. This result establishes the structure of the product of this diazonium coupling reaction as the 1-(1-imidazolidinylmethyl)Imidazolidine Derivative and not the alternate tetraazabicyclo[4.4.1]undecane Derivative. Crystal data: 1 C_29H_34N_10, orthorhombic, space group Pbca , a = 17.946(1), b = 13.106(1), c = 24.108(1) Å, V = 5670.6(3) Å^3, for Z = 8.
