Immunohaematology

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Castañeda Orjuela, Carlos Andres - One of the best experts on this subject based on the ideXlab platform.

  • Costos de la prueba de tamización para la enfermedad de Chagas en donantes de dos bancos de sangre de Colombia, 2015
    Instituto Nacional de Salud, 2018
    Co-Authors: Alvis, Nelso José, Diaz, Diana Patricia, Castillo Liliana, Ermudez, María Isabel, Errio, Olga Maritza, Eltra Mauricio, Alvis, Nelso Rafael, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introduction: Transfusion is a mechanism of transmission of Chagas’ disease. There are no studies on the costs of the screening test in Colombian blood banks.Objective: To estimate the costs of the screening test for Chagas’ disease among blood donors in two Colombian blood banks, 2015.Materials and methods: We conducted a micro-costing study from the perspective of the health care provider to estimate the cost of Chagas’ disease testing in two blood banks, Banco de Sangre de la Cruz Roja, Seccional Bolívar, and Banco de Sangre del Hospital de Yopal, Casanare, taking into account four cost categories: 1) Administrative costs: public services and insurance costs were calculated based on the blood bank area in square meters; 2) capital costs: building and equipment costs that were annualized using a 3% discount rate and a lifespan of 20 years for building and five for equipment; 3) costs of Chagas’ disease test materials and reagents adjusted by blood bank production level, and 4) costs of staff in charge of Chagas’ disease test processing. The costs of transfusion bagsand immunohematology tests are also reported.Results: The cost of Chagas’ disease test in the blood bank of Seccional Bolívar was COP$ 37,804 (USD$ 12), and the blood bag and immunohematology test costs were COP$ 25,941 (USD$ 8.2) and COP$ 6,800 (USD$ 2.2), respectively. In the blood bank of Yopal, Casanare, the costs were COP$ 77,384 (USD$ 24.6), COP$ 30,141 (USD$ 9.6) and COP$ 12,627 (USD$ 4), respectively. Personnel cost accounted for the highest percentage of the total cost for both blood banks (47.5% in Seccional Bolívar, and 55.7% in Yopal, Casanare).Conclusion: Our results are an important input for the planning of services and cost-effectiveness studies for screening tests for Chagas’ disease in Colombian blood banks.Introducción. La transfusión es un mecanismo de transmisión de la enfermedad de Chagas. No se han hecho estudios de costos de la prueba de tamización en bancos de sangre de Colombia.Objetivo. Estimar los costos de la prueba de tamización para la enfermedad de Chagas en donantes de bancos de sangre de Colombia, 2015.Materiales y métodos. Se hizo un estudio de costos desde la perspectiva del prestador de servicios en los bancos de sangre de la Cruz Roja, seccional Bolívar, y del Hospital de Yopal, Casanare, que incluyó: 1) gastos administrativos, es decir, costos de servicios públicos y seguros asignados según los metros cuadrados de las instalaciones del banco de sangre; 2) costos de capital, es decir, edificación y equipos, anualizados con una tasa de descuento de 3 % y considerando una vida útil de 20 y cinco años, respectivamente; 3) costos de insumos y materiales ajustados al nivel de producción, y 4) costos del recurso humano encargado del procesamiento de las pruebas. Se reportó, asimismo, el costo de las bolsas y de las pruebas de inmunohematología.Resultados. En el banco de sangre de la Cruz Roja, seccional Bolívar, el costo de la prueba fue de COP$ 37.804 (USD$ 12), mientras que la bolsa y la prueba de inmunohematología costaron COP$25.942 (USD$ 8,2) y COP$ 6.800 (USD$ 2,2), respectivamente. En el banco de sangre del Hospital de Yopal, los costos ascendieron a COP$ 77.384 (USD$ 24,6), COP$ 30.141 (USD$ 9,6) y COP$ 12.627 (USD$ 4), respectivamente. La mayor participación en el costo de la prueba correspondió al recurso humano (47,5 % en Cartagena y 55,7 % en Yopal).Conclusiones. Estos resultados son importantes para la planificación de los servicios y los análisis de costo-efectividad de la prueba de tamización para la enfermedad de Chagas en los bancos de sangre

  • Costos de la prueba de tamización para la enfermedad de Chagas en donantes de dos bancos de sangre de Colombia, 2015
    Biomedica, 2018
    Co-Authors: Alvis Zakzuk, Nelso Jose, Diaz, Diana Patricia, Castillo Liliana, Alvis Guzman, Nelso Rafael, Ermudez, María Isabel, Errio, Olga Maritza, Eltra Mauricio, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introduction: Transfusion is a mechanism of transmission of Chagas' disease. There are no studies on the costs of the screening test in Colombian blood banks. Objective: To estimate the costs of the screening test for Chagas' disease among blood donors in two Colombian blood banks, 2015. Materials and methods: We conducted a micro-costing study from the perspective of the health care provider to estimate the cost of Chagas' disease testing in two blood banks, Banco de Sangre de la Cruz Roja, Seccional Bolívar, and Banco de Sangre del Hospital de Yopal, Casanare, taking into account four cost categories: 1) Administrative costs: public services and insurance costs were calculated based on the blood bank area in square meters; 2) capital costs: building and equipment costs that were annualized using a 3% discount rate and a lifespan of 20 years for building and five for equipment; 3) costs of Chagas' disease test materials and reagents adjusted by blood bank production level, and 4) costs of staff in charge of Chagas' disease test processing. The costs of transfusion bags and immunohematology tests are also reported. Results: The cost of Chagas' disease test in the blood bank of Seccional Bolívar was COP$ 37,804 (USD$ 12), and the blood bag and immunohematology test costs were COP$ 25,941 (USD$ 8.2) and COP$ 6,800 (USD$ 2.2), respectively. In the blood bank of Yopal, Casanare, the costs were COP$ 77,384 (USD$ 24.6), COP$ 30,141 (USD$ 9.6) and COP$ 12,627 (USD$ 4), respectively. Personnel cost accounted for the highest percentage of the total cost for both blood banks (47.5% in Seccional Bolívar, and 55.7% in Yopal, Casanare). Conclusion: Our results are an important input for the planning of services and cost-effectiveness studies for screening tests for Chagas' disease in Colombian blood banks

  • Screening costs for Chagas disease in donors of Colombian blood banks, 2015
    Biomédica, 2018
    Co-Authors: Alvis Zakzuk, Nelso Jose, Castillo Liliana, Eltra Mauricio, Patricia Díaz Diana, Rafael Alvis Nelso, Isabel Bermúdez María, Maritza Berrío Olga, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introducción. La transfusión es un mecanismo de transmisión de la enfermedad de Chagas. No se han hecho estudios de costos de la prueba de tamización en bancos de sangre de Colombia.Objetivo. Estimar los costos de la prueba de tamización para la enfermedad de Chagas en donantes de bancos de sangre de Colombia, 2015. Materiales y métodos. Se hizo un estudio de costos desde la perspectiva del prestador de servicios en los bancos de sangre de la Cruz Roja, seccional Bolívar, y del Hospital de Yopal, Casanare, que incluyó: 1) gastos administrativos, es decir, costos de servicios públicos y seguros asignados según los metros cuadrados de las instalaciones del banco de sangre; 2) costos de capital, es decir, edificación y equipos, anualizados con una tasa de descuento de 3 % y considerando una vida útil de 20 y cinco años, respectivamente; 3) costos de insumos y materiales ajustados al nivel de producción, y 4) costos del recurso humano encargado del procesamiento de las pruebas. Se reportó, asimismo, el costo de las bolsas y de las pruebas de inmunohematología.Resultados. En el banco de sangre de la Cruz Roja, seccional Bolívar, el costo de la prueba fue de COP$ 37.804 (USD$ 12), mientras que la bolsa y la prueba de inmunohematología costaron COP$ 25.942 (USD$ 8,2) y COP$ 6.800 (USD$ 2,2), respectivamente. En el banco de sangre del Hospital de Yopal, los costos ascendieron a COP$ 77.384 (USD$ 24,6), COP$ 30.141 (USD$ 9,6) y COP$ 12.627 (USD$ 4), respectivamente. La mayor participación en el costo de la prueba correspondió al recurso humano (47,5 % en Cartagena y 55,7 % en Yopal).Conclusiones. Estos resultados son importantes para la planificación de los servicios y los análisis de costo-efectividad de la prueba de tamización para la enfermedad de Chagas en los bancos de sangreIntroduction. Transfusion is a mechanism of transmission of Chagas disease. There have been no cost studies of the screening test in Colombian blood banks. Objective. Estimate the costs of the screening test for Chagas disease in donors of Colombian blood banks, 2015. Materials and methods. A cost study was made from the perspective of the service provider in the blood banks of the Red Cross, Bolívar branch, and the Yopal Hospital, Casanare, which included: 1) administrative expenses, that is, costs of public services and insurance assigned according to the square meters of the blood bank facilities; 2) capital costs, that is, construction and equipment, annualized with a discount rate of 3% and considering a useful life of 20 and five years, respectively; 3) costs of inputs and materials adjusted to the level of production, and 4) costs of human resources in charge of processing the tests. The cost of the bags and the immunohematology tests were also reported. Results. In the blood bank of the Red Cross, section Bolivar, the cost of the test was COP $ 37,804 (USD $ 12), while the bag and the immunohematology test cost COP $ 25,942 (USD $ 8.2) and COP $ 6,800 (USD $ 2,2), respectively. In the blood bank of Yopal Hospital, costs amounted to COP $ 77,384 (USD $ 24.6), COP $ 30,141 (USD $ 9.6) and COP $ 12,627 (USD $ 4), respectively. The greatest share of the cost of the test corresponded to human resources (47.5% in Cartagena and 55.7% in Yopal). Conclusions. These results are important for the planning of the services and the cost-effectiveness analysis of the screening test for Chagas disease in blood banks

Eltra Mauricio - One of the best experts on this subject based on the ideXlab platform.

  • Costos de la prueba de tamización para la enfermedad de Chagas en donantes de dos bancos de sangre de Colombia, 2015
    Instituto Nacional de Salud, 2018
    Co-Authors: Alvis, Nelso José, Diaz, Diana Patricia, Castillo Liliana, Ermudez, María Isabel, Errio, Olga Maritza, Eltra Mauricio, Alvis, Nelso Rafael, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introduction: Transfusion is a mechanism of transmission of Chagas’ disease. There are no studies on the costs of the screening test in Colombian blood banks.Objective: To estimate the costs of the screening test for Chagas’ disease among blood donors in two Colombian blood banks, 2015.Materials and methods: We conducted a micro-costing study from the perspective of the health care provider to estimate the cost of Chagas’ disease testing in two blood banks, Banco de Sangre de la Cruz Roja, Seccional Bolívar, and Banco de Sangre del Hospital de Yopal, Casanare, taking into account four cost categories: 1) Administrative costs: public services and insurance costs were calculated based on the blood bank area in square meters; 2) capital costs: building and equipment costs that were annualized using a 3% discount rate and a lifespan of 20 years for building and five for equipment; 3) costs of Chagas’ disease test materials and reagents adjusted by blood bank production level, and 4) costs of staff in charge of Chagas’ disease test processing. The costs of transfusion bagsand immunohematology tests are also reported.Results: The cost of Chagas’ disease test in the blood bank of Seccional Bolívar was COP$ 37,804 (USD$ 12), and the blood bag and immunohematology test costs were COP$ 25,941 (USD$ 8.2) and COP$ 6,800 (USD$ 2.2), respectively. In the blood bank of Yopal, Casanare, the costs were COP$ 77,384 (USD$ 24.6), COP$ 30,141 (USD$ 9.6) and COP$ 12,627 (USD$ 4), respectively. Personnel cost accounted for the highest percentage of the total cost for both blood banks (47.5% in Seccional Bolívar, and 55.7% in Yopal, Casanare).Conclusion: Our results are an important input for the planning of services and cost-effectiveness studies for screening tests for Chagas’ disease in Colombian blood banks.Introducción. La transfusión es un mecanismo de transmisión de la enfermedad de Chagas. No se han hecho estudios de costos de la prueba de tamización en bancos de sangre de Colombia.Objetivo. Estimar los costos de la prueba de tamización para la enfermedad de Chagas en donantes de bancos de sangre de Colombia, 2015.Materiales y métodos. Se hizo un estudio de costos desde la perspectiva del prestador de servicios en los bancos de sangre de la Cruz Roja, seccional Bolívar, y del Hospital de Yopal, Casanare, que incluyó: 1) gastos administrativos, es decir, costos de servicios públicos y seguros asignados según los metros cuadrados de las instalaciones del banco de sangre; 2) costos de capital, es decir, edificación y equipos, anualizados con una tasa de descuento de 3 % y considerando una vida útil de 20 y cinco años, respectivamente; 3) costos de insumos y materiales ajustados al nivel de producción, y 4) costos del recurso humano encargado del procesamiento de las pruebas. Se reportó, asimismo, el costo de las bolsas y de las pruebas de inmunohematología.Resultados. En el banco de sangre de la Cruz Roja, seccional Bolívar, el costo de la prueba fue de COP$ 37.804 (USD$ 12), mientras que la bolsa y la prueba de inmunohematología costaron COP$25.942 (USD$ 8,2) y COP$ 6.800 (USD$ 2,2), respectivamente. En el banco de sangre del Hospital de Yopal, los costos ascendieron a COP$ 77.384 (USD$ 24,6), COP$ 30.141 (USD$ 9,6) y COP$ 12.627 (USD$ 4), respectivamente. La mayor participación en el costo de la prueba correspondió al recurso humano (47,5 % en Cartagena y 55,7 % en Yopal).Conclusiones. Estos resultados son importantes para la planificación de los servicios y los análisis de costo-efectividad de la prueba de tamización para la enfermedad de Chagas en los bancos de sangre

  • Costos de la prueba de tamización para la enfermedad de Chagas en donantes de dos bancos de sangre de Colombia, 2015
    Biomedica, 2018
    Co-Authors: Alvis Zakzuk, Nelso Jose, Diaz, Diana Patricia, Castillo Liliana, Alvis Guzman, Nelso Rafael, Ermudez, María Isabel, Errio, Olga Maritza, Eltra Mauricio, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introduction: Transfusion is a mechanism of transmission of Chagas' disease. There are no studies on the costs of the screening test in Colombian blood banks. Objective: To estimate the costs of the screening test for Chagas' disease among blood donors in two Colombian blood banks, 2015. Materials and methods: We conducted a micro-costing study from the perspective of the health care provider to estimate the cost of Chagas' disease testing in two blood banks, Banco de Sangre de la Cruz Roja, Seccional Bolívar, and Banco de Sangre del Hospital de Yopal, Casanare, taking into account four cost categories: 1) Administrative costs: public services and insurance costs were calculated based on the blood bank area in square meters; 2) capital costs: building and equipment costs that were annualized using a 3% discount rate and a lifespan of 20 years for building and five for equipment; 3) costs of Chagas' disease test materials and reagents adjusted by blood bank production level, and 4) costs of staff in charge of Chagas' disease test processing. The costs of transfusion bags and immunohematology tests are also reported. Results: The cost of Chagas' disease test in the blood bank of Seccional Bolívar was COP$ 37,804 (USD$ 12), and the blood bag and immunohematology test costs were COP$ 25,941 (USD$ 8.2) and COP$ 6,800 (USD$ 2.2), respectively. In the blood bank of Yopal, Casanare, the costs were COP$ 77,384 (USD$ 24.6), COP$ 30,141 (USD$ 9.6) and COP$ 12,627 (USD$ 4), respectively. Personnel cost accounted for the highest percentage of the total cost for both blood banks (47.5% in Seccional Bolívar, and 55.7% in Yopal, Casanare). Conclusion: Our results are an important input for the planning of services and cost-effectiveness studies for screening tests for Chagas' disease in Colombian blood banks

  • Screening costs for Chagas disease in donors of Colombian blood banks, 2015
    Biomédica, 2018
    Co-Authors: Alvis Zakzuk, Nelso Jose, Castillo Liliana, Eltra Mauricio, Patricia Díaz Diana, Rafael Alvis Nelso, Isabel Bermúdez María, Maritza Berrío Olga, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introducción. La transfusión es un mecanismo de transmisión de la enfermedad de Chagas. No se han hecho estudios de costos de la prueba de tamización en bancos de sangre de Colombia.Objetivo. Estimar los costos de la prueba de tamización para la enfermedad de Chagas en donantes de bancos de sangre de Colombia, 2015. Materiales y métodos. Se hizo un estudio de costos desde la perspectiva del prestador de servicios en los bancos de sangre de la Cruz Roja, seccional Bolívar, y del Hospital de Yopal, Casanare, que incluyó: 1) gastos administrativos, es decir, costos de servicios públicos y seguros asignados según los metros cuadrados de las instalaciones del banco de sangre; 2) costos de capital, es decir, edificación y equipos, anualizados con una tasa de descuento de 3 % y considerando una vida útil de 20 y cinco años, respectivamente; 3) costos de insumos y materiales ajustados al nivel de producción, y 4) costos del recurso humano encargado del procesamiento de las pruebas. Se reportó, asimismo, el costo de las bolsas y de las pruebas de inmunohematología.Resultados. En el banco de sangre de la Cruz Roja, seccional Bolívar, el costo de la prueba fue de COP$ 37.804 (USD$ 12), mientras que la bolsa y la prueba de inmunohematología costaron COP$ 25.942 (USD$ 8,2) y COP$ 6.800 (USD$ 2,2), respectivamente. En el banco de sangre del Hospital de Yopal, los costos ascendieron a COP$ 77.384 (USD$ 24,6), COP$ 30.141 (USD$ 9,6) y COP$ 12.627 (USD$ 4), respectivamente. La mayor participación en el costo de la prueba correspondió al recurso humano (47,5 % en Cartagena y 55,7 % en Yopal).Conclusiones. Estos resultados son importantes para la planificación de los servicios y los análisis de costo-efectividad de la prueba de tamización para la enfermedad de Chagas en los bancos de sangreIntroduction. Transfusion is a mechanism of transmission of Chagas disease. There have been no cost studies of the screening test in Colombian blood banks. Objective. Estimate the costs of the screening test for Chagas disease in donors of Colombian blood banks, 2015. Materials and methods. A cost study was made from the perspective of the service provider in the blood banks of the Red Cross, Bolívar branch, and the Yopal Hospital, Casanare, which included: 1) administrative expenses, that is, costs of public services and insurance assigned according to the square meters of the blood bank facilities; 2) capital costs, that is, construction and equipment, annualized with a discount rate of 3% and considering a useful life of 20 and five years, respectively; 3) costs of inputs and materials adjusted to the level of production, and 4) costs of human resources in charge of processing the tests. The cost of the bags and the immunohematology tests were also reported. Results. In the blood bank of the Red Cross, section Bolivar, the cost of the test was COP $ 37,804 (USD $ 12), while the bag and the immunohematology test cost COP $ 25,942 (USD $ 8.2) and COP $ 6,800 (USD $ 2,2), respectively. In the blood bank of Yopal Hospital, costs amounted to COP $ 77,384 (USD $ 24.6), COP $ 30,141 (USD $ 9.6) and COP $ 12,627 (USD $ 4), respectively. The greatest share of the cost of the test corresponded to human resources (47.5% in Cartagena and 55.7% in Yopal). Conclusions. These results are important for the planning of the services and the cost-effectiveness analysis of the screening test for Chagas disease in blood banks

Castillo Liliana - One of the best experts on this subject based on the ideXlab platform.

  • Costos de la prueba de tamización para la enfermedad de Chagas en donantes de dos bancos de sangre de Colombia, 2015
    Instituto Nacional de Salud, 2018
    Co-Authors: Alvis, Nelso José, Diaz, Diana Patricia, Castillo Liliana, Ermudez, María Isabel, Errio, Olga Maritza, Eltra Mauricio, Alvis, Nelso Rafael, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introduction: Transfusion is a mechanism of transmission of Chagas’ disease. There are no studies on the costs of the screening test in Colombian blood banks.Objective: To estimate the costs of the screening test for Chagas’ disease among blood donors in two Colombian blood banks, 2015.Materials and methods: We conducted a micro-costing study from the perspective of the health care provider to estimate the cost of Chagas’ disease testing in two blood banks, Banco de Sangre de la Cruz Roja, Seccional Bolívar, and Banco de Sangre del Hospital de Yopal, Casanare, taking into account four cost categories: 1) Administrative costs: public services and insurance costs were calculated based on the blood bank area in square meters; 2) capital costs: building and equipment costs that were annualized using a 3% discount rate and a lifespan of 20 years for building and five for equipment; 3) costs of Chagas’ disease test materials and reagents adjusted by blood bank production level, and 4) costs of staff in charge of Chagas’ disease test processing. The costs of transfusion bagsand immunohematology tests are also reported.Results: The cost of Chagas’ disease test in the blood bank of Seccional Bolívar was COP$ 37,804 (USD$ 12), and the blood bag and immunohematology test costs were COP$ 25,941 (USD$ 8.2) and COP$ 6,800 (USD$ 2.2), respectively. In the blood bank of Yopal, Casanare, the costs were COP$ 77,384 (USD$ 24.6), COP$ 30,141 (USD$ 9.6) and COP$ 12,627 (USD$ 4), respectively. Personnel cost accounted for the highest percentage of the total cost for both blood banks (47.5% in Seccional Bolívar, and 55.7% in Yopal, Casanare).Conclusion: Our results are an important input for the planning of services and cost-effectiveness studies for screening tests for Chagas’ disease in Colombian blood banks.Introducción. La transfusión es un mecanismo de transmisión de la enfermedad de Chagas. No se han hecho estudios de costos de la prueba de tamización en bancos de sangre de Colombia.Objetivo. Estimar los costos de la prueba de tamización para la enfermedad de Chagas en donantes de bancos de sangre de Colombia, 2015.Materiales y métodos. Se hizo un estudio de costos desde la perspectiva del prestador de servicios en los bancos de sangre de la Cruz Roja, seccional Bolívar, y del Hospital de Yopal, Casanare, que incluyó: 1) gastos administrativos, es decir, costos de servicios públicos y seguros asignados según los metros cuadrados de las instalaciones del banco de sangre; 2) costos de capital, es decir, edificación y equipos, anualizados con una tasa de descuento de 3 % y considerando una vida útil de 20 y cinco años, respectivamente; 3) costos de insumos y materiales ajustados al nivel de producción, y 4) costos del recurso humano encargado del procesamiento de las pruebas. Se reportó, asimismo, el costo de las bolsas y de las pruebas de inmunohematología.Resultados. En el banco de sangre de la Cruz Roja, seccional Bolívar, el costo de la prueba fue de COP$ 37.804 (USD$ 12), mientras que la bolsa y la prueba de inmunohematología costaron COP$25.942 (USD$ 8,2) y COP$ 6.800 (USD$ 2,2), respectivamente. En el banco de sangre del Hospital de Yopal, los costos ascendieron a COP$ 77.384 (USD$ 24,6), COP$ 30.141 (USD$ 9,6) y COP$ 12.627 (USD$ 4), respectivamente. La mayor participación en el costo de la prueba correspondió al recurso humano (47,5 % en Cartagena y 55,7 % en Yopal).Conclusiones. Estos resultados son importantes para la planificación de los servicios y los análisis de costo-efectividad de la prueba de tamización para la enfermedad de Chagas en los bancos de sangre

  • Costos de la prueba de tamización para la enfermedad de Chagas en donantes de dos bancos de sangre de Colombia, 2015
    Biomedica, 2018
    Co-Authors: Alvis Zakzuk, Nelso Jose, Diaz, Diana Patricia, Castillo Liliana, Alvis Guzman, Nelso Rafael, Ermudez, María Isabel, Errio, Olga Maritza, Eltra Mauricio, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introduction: Transfusion is a mechanism of transmission of Chagas' disease. There are no studies on the costs of the screening test in Colombian blood banks. Objective: To estimate the costs of the screening test for Chagas' disease among blood donors in two Colombian blood banks, 2015. Materials and methods: We conducted a micro-costing study from the perspective of the health care provider to estimate the cost of Chagas' disease testing in two blood banks, Banco de Sangre de la Cruz Roja, Seccional Bolívar, and Banco de Sangre del Hospital de Yopal, Casanare, taking into account four cost categories: 1) Administrative costs: public services and insurance costs were calculated based on the blood bank area in square meters; 2) capital costs: building and equipment costs that were annualized using a 3% discount rate and a lifespan of 20 years for building and five for equipment; 3) costs of Chagas' disease test materials and reagents adjusted by blood bank production level, and 4) costs of staff in charge of Chagas' disease test processing. The costs of transfusion bags and immunohematology tests are also reported. Results: The cost of Chagas' disease test in the blood bank of Seccional Bolívar was COP$ 37,804 (USD$ 12), and the blood bag and immunohematology test costs were COP$ 25,941 (USD$ 8.2) and COP$ 6,800 (USD$ 2.2), respectively. In the blood bank of Yopal, Casanare, the costs were COP$ 77,384 (USD$ 24.6), COP$ 30,141 (USD$ 9.6) and COP$ 12,627 (USD$ 4), respectively. Personnel cost accounted for the highest percentage of the total cost for both blood banks (47.5% in Seccional Bolívar, and 55.7% in Yopal, Casanare). Conclusion: Our results are an important input for the planning of services and cost-effectiveness studies for screening tests for Chagas' disease in Colombian blood banks

  • Screening costs for Chagas disease in donors of Colombian blood banks, 2015
    Biomédica, 2018
    Co-Authors: Alvis Zakzuk, Nelso Jose, Castillo Liliana, Eltra Mauricio, Patricia Díaz Diana, Rafael Alvis Nelso, Isabel Bermúdez María, Maritza Berrío Olga, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introducción. La transfusión es un mecanismo de transmisión de la enfermedad de Chagas. No se han hecho estudios de costos de la prueba de tamización en bancos de sangre de Colombia.Objetivo. Estimar los costos de la prueba de tamización para la enfermedad de Chagas en donantes de bancos de sangre de Colombia, 2015. Materiales y métodos. Se hizo un estudio de costos desde la perspectiva del prestador de servicios en los bancos de sangre de la Cruz Roja, seccional Bolívar, y del Hospital de Yopal, Casanare, que incluyó: 1) gastos administrativos, es decir, costos de servicios públicos y seguros asignados según los metros cuadrados de las instalaciones del banco de sangre; 2) costos de capital, es decir, edificación y equipos, anualizados con una tasa de descuento de 3 % y considerando una vida útil de 20 y cinco años, respectivamente; 3) costos de insumos y materiales ajustados al nivel de producción, y 4) costos del recurso humano encargado del procesamiento de las pruebas. Se reportó, asimismo, el costo de las bolsas y de las pruebas de inmunohematología.Resultados. En el banco de sangre de la Cruz Roja, seccional Bolívar, el costo de la prueba fue de COP$ 37.804 (USD$ 12), mientras que la bolsa y la prueba de inmunohematología costaron COP$ 25.942 (USD$ 8,2) y COP$ 6.800 (USD$ 2,2), respectivamente. En el banco de sangre del Hospital de Yopal, los costos ascendieron a COP$ 77.384 (USD$ 24,6), COP$ 30.141 (USD$ 9,6) y COP$ 12.627 (USD$ 4), respectivamente. La mayor participación en el costo de la prueba correspondió al recurso humano (47,5 % en Cartagena y 55,7 % en Yopal).Conclusiones. Estos resultados son importantes para la planificación de los servicios y los análisis de costo-efectividad de la prueba de tamización para la enfermedad de Chagas en los bancos de sangreIntroduction. Transfusion is a mechanism of transmission of Chagas disease. There have been no cost studies of the screening test in Colombian blood banks. Objective. Estimate the costs of the screening test for Chagas disease in donors of Colombian blood banks, 2015. Materials and methods. A cost study was made from the perspective of the service provider in the blood banks of the Red Cross, Bolívar branch, and the Yopal Hospital, Casanare, which included: 1) administrative expenses, that is, costs of public services and insurance assigned according to the square meters of the blood bank facilities; 2) capital costs, that is, construction and equipment, annualized with a discount rate of 3% and considering a useful life of 20 and five years, respectively; 3) costs of inputs and materials adjusted to the level of production, and 4) costs of human resources in charge of processing the tests. The cost of the bags and the immunohematology tests were also reported. Results. In the blood bank of the Red Cross, section Bolivar, the cost of the test was COP $ 37,804 (USD $ 12), while the bag and the immunohematology test cost COP $ 25,942 (USD $ 8.2) and COP $ 6,800 (USD $ 2,2), respectively. In the blood bank of Yopal Hospital, costs amounted to COP $ 77,384 (USD $ 24.6), COP $ 30,141 (USD $ 9.6) and COP $ 12,627 (USD $ 4), respectively. The greatest share of the cost of the test corresponded to human resources (47.5% in Cartagena and 55.7% in Yopal). Conclusions. These results are important for the planning of the services and the cost-effectiveness analysis of the screening test for Chagas disease in blood banks

Willy A Flegel - One of the best experts on this subject based on the ideXlab platform.

  • molecular Immunohaematology round table discussions at the aabb annual meeting philadelphia 2014
    Vox Sanguinis, 2016
    Co-Authors: Willy A Flegel, Joann M Moulds, Margaret A Keller, Ellen Klapper, Gary Stack, Maryse Stlouis, Christopher A Tormey, F Noizatpirenne, Nadine Shehata, D A Waxman
    Abstract:

    Use of molecular-based Immunohaematology testing is becoming more widespread worldwide in laboratories that are accustomed to the use of blood group serology alone. Molecular Immunohaematology issues may be challenging even for some established professionals in the field of blood group serology. At an international meeting, we offered round table discussions on four patient-related and two donor-related topics, which are current and possibly controversial. Six molecular Immunohaematology questions were addressed: applications for highly contagious infections, such as Ebola; utility after transfusions in the preceding three months; root cause analysis for unexplained occurrence of anti-D; acceptable turnaround time for red cell genotyping of patients; criteria for donor cohorts to be genotyped; and quality assurance for discrepancies between serological phenotype and licensed red cell genotyping. The opinions polled in this workshop with an international assemblage of more than 100 transfusion medicine specialists were discussed in the light of education and training opportunities and the development of guidance in the field. We provide a summary report of the participants’ input to our questions and discuss the topics.

  • molecular Immunohaematology round table discussions at the aabb annual meeting denver 2013
    Blood Transfusion, 2015
    Co-Authors: Willy A Flegel, Joann M Moulds, Susan T Johnson, Margaret A Keller, Ellen Klapper, Hanh Khuu, Axel Seltsam, Gary Stack, Maryse Stlouis, Christopher A Tormey
    Abstract:

    Well trained, experienced serologists in transfusion medicine laboratories have been familiar with blood group serology for decades. With the advent of molecular Immunohaematology, there is a need to adopt and embrace the clinical and diagnostic applications in order for patients to benefit from the advances that this technology offers1–3. We organised an international forum to discuss molecular Immunohaematology concepts that may be challenging even for some established professionals in the field of serology. The objectives of the session were two-fold. First, the session allowed networking among Immunohaematology professionals who have an interest in the application of molecular immuno-haematology and blood group genetics while meeting with leaders in the field of molecular Immunohaematology. By giving input and asking questions, the participants could define their knowledge relative to the experience of the group as a whole. Second, the discussions and the input from experienced professionals were recorded. This approach allowed documentation of current knowledge, as well as acceptance and concerns of the participants. It is useful to gathering information in this field, because the perception at the level of the participants is critical for shaping the adoption of molecular Immunohaematology. We provide a summary report of the items discussed and issues raised by the participants. The results describe the status of molecular Immunohaematology within this large group of experienced professionals in transfusion medicine laboratories and can guide targeted educational efforts.

  • applying molecular Immunohaematology to regularly transfused thalassaemic patients in thailand
    Vox Sanguinis, 2014
    Co-Authors: Pairaya Rujirojindakul, Willy A Flegel
    Abstract:

    Background Red blood cell transfusion is the principal therapy in patients with severe thalassaemias and haemoglobinopathies, which are prevalent in Thailand. Serological red blood cell typing is confounded by chronic transfusion, because of circulating donor red blood cells. We evaluated the concordance of serological phenotypes between a routine and a reference laboratory and with red cell genotyping. Materials and methods Ten consecutive Thai patients with β-thalassemia major who received regular transfusions were enrolled in Thailand. Phenotypes were tested serologically at Songklanagarind Hospital and at the National Institutes of Health. Red blood cell genotyping was performed with commercially available kits and a platform. Results In only three patients was the red cell genotyping concordant with the serological phenotypes for five antithetical antigen pairs in four blood group systems at the two institutions. At the National Institutes of Health, 32 of the 100 serological tests yielded invalid or discrepant results. The positive predictive value of serology did not reach 1 for any blood group system at either of the two institutions in this set of ten patients. Discussion Within this small study, numerous discrepancies were observed between serological phenotypes at the two institutes; red cell genotyping enabled determination of the blood group when serology failed due to transfused red blood cells. We question the utility of serological tests in regularly transfused paediatric patients and propose relying solely on red cell genotyping, which requires training for laboratory personnel and physicians. Red cell genotyping outperformed red cell serology by an order of magnitude in regularly transfused patients.

Alvis Zakzuk, Nelso Jose - One of the best experts on this subject based on the ideXlab platform.

  • Costos de la prueba de tamización para la enfermedad de Chagas en donantes de dos bancos de sangre de Colombia, 2015
    Biomedica, 2018
    Co-Authors: Alvis Zakzuk, Nelso Jose, Diaz, Diana Patricia, Castillo Liliana, Alvis Guzman, Nelso Rafael, Ermudez, María Isabel, Errio, Olga Maritza, Eltra Mauricio, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introduction: Transfusion is a mechanism of transmission of Chagas' disease. There are no studies on the costs of the screening test in Colombian blood banks. Objective: To estimate the costs of the screening test for Chagas' disease among blood donors in two Colombian blood banks, 2015. Materials and methods: We conducted a micro-costing study from the perspective of the health care provider to estimate the cost of Chagas' disease testing in two blood banks, Banco de Sangre de la Cruz Roja, Seccional Bolívar, and Banco de Sangre del Hospital de Yopal, Casanare, taking into account four cost categories: 1) Administrative costs: public services and insurance costs were calculated based on the blood bank area in square meters; 2) capital costs: building and equipment costs that were annualized using a 3% discount rate and a lifespan of 20 years for building and five for equipment; 3) costs of Chagas' disease test materials and reagents adjusted by blood bank production level, and 4) costs of staff in charge of Chagas' disease test processing. The costs of transfusion bags and immunohematology tests are also reported. Results: The cost of Chagas' disease test in the blood bank of Seccional Bolívar was COP$ 37,804 (USD$ 12), and the blood bag and immunohematology test costs were COP$ 25,941 (USD$ 8.2) and COP$ 6,800 (USD$ 2.2), respectively. In the blood bank of Yopal, Casanare, the costs were COP$ 77,384 (USD$ 24.6), COP$ 30,141 (USD$ 9.6) and COP$ 12,627 (USD$ 4), respectively. Personnel cost accounted for the highest percentage of the total cost for both blood banks (47.5% in Seccional Bolívar, and 55.7% in Yopal, Casanare). Conclusion: Our results are an important input for the planning of services and cost-effectiveness studies for screening tests for Chagas' disease in Colombian blood banks

  • Screening costs for Chagas disease in donors of Colombian blood banks, 2015
    Biomédica, 2018
    Co-Authors: Alvis Zakzuk, Nelso Jose, Castillo Liliana, Eltra Mauricio, Patricia Díaz Diana, Rafael Alvis Nelso, Isabel Bermúdez María, Maritza Berrío Olga, Castañeda Orjuela, Carlos Andres
    Abstract:

    Introducción. La transfusión es un mecanismo de transmisión de la enfermedad de Chagas. No se han hecho estudios de costos de la prueba de tamización en bancos de sangre de Colombia.Objetivo. Estimar los costos de la prueba de tamización para la enfermedad de Chagas en donantes de bancos de sangre de Colombia, 2015. Materiales y métodos. Se hizo un estudio de costos desde la perspectiva del prestador de servicios en los bancos de sangre de la Cruz Roja, seccional Bolívar, y del Hospital de Yopal, Casanare, que incluyó: 1) gastos administrativos, es decir, costos de servicios públicos y seguros asignados según los metros cuadrados de las instalaciones del banco de sangre; 2) costos de capital, es decir, edificación y equipos, anualizados con una tasa de descuento de 3 % y considerando una vida útil de 20 y cinco años, respectivamente; 3) costos de insumos y materiales ajustados al nivel de producción, y 4) costos del recurso humano encargado del procesamiento de las pruebas. Se reportó, asimismo, el costo de las bolsas y de las pruebas de inmunohematología.Resultados. En el banco de sangre de la Cruz Roja, seccional Bolívar, el costo de la prueba fue de COP$ 37.804 (USD$ 12), mientras que la bolsa y la prueba de inmunohematología costaron COP$ 25.942 (USD$ 8,2) y COP$ 6.800 (USD$ 2,2), respectivamente. En el banco de sangre del Hospital de Yopal, los costos ascendieron a COP$ 77.384 (USD$ 24,6), COP$ 30.141 (USD$ 9,6) y COP$ 12.627 (USD$ 4), respectivamente. La mayor participación en el costo de la prueba correspondió al recurso humano (47,5 % en Cartagena y 55,7 % en Yopal).Conclusiones. Estos resultados son importantes para la planificación de los servicios y los análisis de costo-efectividad de la prueba de tamización para la enfermedad de Chagas en los bancos de sangreIntroduction. Transfusion is a mechanism of transmission of Chagas disease. There have been no cost studies of the screening test in Colombian blood banks. Objective. Estimate the costs of the screening test for Chagas disease in donors of Colombian blood banks, 2015. Materials and methods. A cost study was made from the perspective of the service provider in the blood banks of the Red Cross, Bolívar branch, and the Yopal Hospital, Casanare, which included: 1) administrative expenses, that is, costs of public services and insurance assigned according to the square meters of the blood bank facilities; 2) capital costs, that is, construction and equipment, annualized with a discount rate of 3% and considering a useful life of 20 and five years, respectively; 3) costs of inputs and materials adjusted to the level of production, and 4) costs of human resources in charge of processing the tests. The cost of the bags and the immunohematology tests were also reported. Results. In the blood bank of the Red Cross, section Bolivar, the cost of the test was COP $ 37,804 (USD $ 12), while the bag and the immunohematology test cost COP $ 25,942 (USD $ 8.2) and COP $ 6,800 (USD $ 2,2), respectively. In the blood bank of Yopal Hospital, costs amounted to COP $ 77,384 (USD $ 24.6), COP $ 30,141 (USD $ 9.6) and COP $ 12,627 (USD $ 4), respectively. The greatest share of the cost of the test corresponded to human resources (47.5% in Cartagena and 55.7% in Yopal). Conclusions. These results are important for the planning of the services and the cost-effectiveness analysis of the screening test for Chagas disease in blood banks