The Experts below are selected from a list of 66120 Experts worldwide ranked by ideXlab platform
Elvira Grandone - One of the best experts on this subject based on the ideXlab platform.
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Liquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant.
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
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Liquid chromatography–tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
Filippo Aucella - One of the best experts on this subject based on the ideXlab platform.
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Liquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant.
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
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Liquid chromatography–tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
Vincenzo Lauriola - One of the best experts on this subject based on the ideXlab platform.
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Liquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant.
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
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Liquid chromatography–tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
Giovanni Luca Tiscia - One of the best experts on this subject based on the ideXlab platform.
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Liquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant.
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
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Liquid chromatography–tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
Gennaro Vecchione - One of the best experts on this subject based on the ideXlab platform.
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Liquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant.
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.
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Liquid chromatography–tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant
Journal of Pharmaceutical and Biomedical Analysis, 2013Co-Authors: Filippo Aucella, Vincenzo Lauriola, Giovanni Luca Tiscia, Gennaro Vecchione, Elvira GrandoneAbstract:Abstract Kidney transplanted patients need Immunosuppressant therapies. Therapeutic drug monitoring approaches produce the optimal clinical outcome is still under debate. This review details strength and limits of methods available: immunoassay and chromatography-based. Liquid chromatography with mass spectrometry detection is a major breakthrough in therapeutic drug monitoring of immunosuppressive agents and is considered as the method of choice in therapeutic drug monitoring (TDM) of Immunosuppressants. Despite the initial high cost for the instrumentation, HPLC–MS is more cost effective than microparticle enzyme immunoassay. The main important features of LC–MS/MS methodology for immunosuppressive drugs are the shortened analysis time, an increased throughput, higher selectivity, specificity, and sensitivity, and low cost of analysis.