The Experts below are selected from a list of 312 Experts worldwide ranked by ideXlab platform
Mark A Wainberg - One of the best experts on this subject based on the ideXlab platform.
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complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in epstein barr virus carrying b cells
Journal of Experimental Medicine, 1990Co-Authors: Michel J Tremblay, Sylvain Meloche, Rafick Pierre Sekaly, Mark A WainbergAbstract:: Although the CD4 glycoprotein is the primary receptor for HIV-1, recent reports have suggested that other molecules might be involved in the enhancement of HIV-1 infection. We investigated the possible role of the complement receptor 2 in enhancement of HIV-1 infection in CD4+ EBV-containing B cells by infecting such cells in the presence of sera from HIV sero-positive donors, with or without added human complement. A marked increase in Production of viral p24 and infectious progeny virus was observed only when infection had been carried out in the presence of human complement. The addition of mAb to the human complement receptor 2 completely inhibited this enhancement. This mechanism was CD4 dependent, suggesting a cooperative effect between these two ligands in the potentiation of viral entry.
Colm Sweeney - One of the best experts on this subject based on the ideXlab platform.
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fugitive emissions from the bakken shale illustrate role of shale Production in global ethane shift
Geophysical Research Letters, 2016Co-Authors: Eric A Kort, M L Smith, Lee T Murray, A Gvakharia, Adam R Brandt, J Peischl, T B Ryerson, Colm SweeneyAbstract:Ethane is the second most abundant atmospheric hydrocarbon, exerts a strong influence on tropospheric ozone, and reduces the atmosphere's oxidative capacity. Global observations showed declining ethane abundances from 1984 to 2010, while a regional measurement indicated increasing levels since 2009, with the reason for this subject to speculation. The Bakken shale is an oil and gas-producing formation centered in North Dakota that experienced a rapid increase in Production beginning in 2010. We use airborne data collected over the North Dakota portion of the Bakken shale in 2014 to calculate ethane emissions of 0.23 ± 0.07 (2σ) Tg/yr, equivalent to 1–3% of total global sources. Emissions of this magnitude impact air quality via concurrent increases in tropospheric ozone. This recently developed large ethane source from one location illustrates the key role of shale oil and gas Production in rising global ethane levels.
Lee T Murray - One of the best experts on this subject based on the ideXlab platform.
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fugitive emissions from the bakken shale illustrate role of shale Production in global ethane shift
Geophysical Research Letters, 2016Co-Authors: Eric A Kort, M L Smith, Lee T Murray, A Gvakharia, Adam R Brandt, J Peischl, T B Ryerson, Colm SweeneyAbstract:Ethane is the second most abundant atmospheric hydrocarbon, exerts a strong influence on tropospheric ozone, and reduces the atmosphere's oxidative capacity. Global observations showed declining ethane abundances from 1984 to 2010, while a regional measurement indicated increasing levels since 2009, with the reason for this subject to speculation. The Bakken shale is an oil and gas-producing formation centered in North Dakota that experienced a rapid increase in Production beginning in 2010. We use airborne data collected over the North Dakota portion of the Bakken shale in 2014 to calculate ethane emissions of 0.23 ± 0.07 (2σ) Tg/yr, equivalent to 1–3% of total global sources. Emissions of this magnitude impact air quality via concurrent increases in tropospheric ozone. This recently developed large ethane source from one location illustrates the key role of shale oil and gas Production in rising global ethane levels.
J Peischl - One of the best experts on this subject based on the ideXlab platform.
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fugitive emissions from the bakken shale illustrate role of shale Production in global ethane shift
Geophysical Research Letters, 2016Co-Authors: Eric A Kort, M L Smith, Lee T Murray, A Gvakharia, Adam R Brandt, J Peischl, T B Ryerson, Colm SweeneyAbstract:Ethane is the second most abundant atmospheric hydrocarbon, exerts a strong influence on tropospheric ozone, and reduces the atmosphere's oxidative capacity. Global observations showed declining ethane abundances from 1984 to 2010, while a regional measurement indicated increasing levels since 2009, with the reason for this subject to speculation. The Bakken shale is an oil and gas-producing formation centered in North Dakota that experienced a rapid increase in Production beginning in 2010. We use airborne data collected over the North Dakota portion of the Bakken shale in 2014 to calculate ethane emissions of 0.23 ± 0.07 (2σ) Tg/yr, equivalent to 1–3% of total global sources. Emissions of this magnitude impact air quality via concurrent increases in tropospheric ozone. This recently developed large ethane source from one location illustrates the key role of shale oil and gas Production in rising global ethane levels.
Michel J Tremblay - One of the best experts on this subject based on the ideXlab platform.
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complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in epstein barr virus carrying b cells
Journal of Experimental Medicine, 1990Co-Authors: Michel J Tremblay, Sylvain Meloche, Rafick Pierre Sekaly, Mark A WainbergAbstract:: Although the CD4 glycoprotein is the primary receptor for HIV-1, recent reports have suggested that other molecules might be involved in the enhancement of HIV-1 infection. We investigated the possible role of the complement receptor 2 in enhancement of HIV-1 infection in CD4+ EBV-containing B cells by infecting such cells in the presence of sera from HIV sero-positive donors, with or without added human complement. A marked increase in Production of viral p24 and infectious progeny virus was observed only when infection had been carried out in the presence of human complement. The addition of mAb to the human complement receptor 2 completely inhibited this enhancement. This mechanism was CD4 dependent, suggesting a cooperative effect between these two ligands in the potentiation of viral entry.
