The Experts below are selected from a list of 15 Experts worldwide ranked by ideXlab platform
Prabhas Moghe - One of the best experts on this subject based on the ideXlab platform.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Brian A. Wall, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature Communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, B. Wall, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique. The short-wavelength Infrared spectral region is of interest for bio-imaging applications as biological tissue is transparent to such light. Here Naczynski et al . fabricate rare-earth-based nanomaterials and demonstrate multispectral, real-time short-wavelength Infrared in-vivo imaging.
Dominik J. Naczynski - One of the best experts on this subject based on the ideXlab platform.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Brian A. Wall, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature Communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, B. Wall, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique. The short-wavelength Infrared spectral region is of interest for bio-imaging applications as biological tissue is transparent to such light. Here Naczynski et al . fabricate rare-earth-based nanomaterials and demonstrate multispectral, real-time short-wavelength Infrared in-vivo imaging.
Mei Chee Tan - One of the best experts on this subject based on the ideXlab platform.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Brian A. Wall, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature Communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, B. Wall, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique. The short-wavelength Infrared spectral region is of interest for bio-imaging applications as biological tissue is transparent to such light. Here Naczynski et al . fabricate rare-earth-based nanomaterials and demonstrate multispectral, real-time short-wavelength Infrared in-vivo imaging.
Margot Zevon - One of the best experts on this subject based on the ideXlab platform.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Brian A. Wall, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature Communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, B. Wall, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique. The short-wavelength Infrared spectral region is of interest for bio-imaging applications as biological tissue is transparent to such light. Here Naczynski et al . fabricate rare-earth-based nanomaterials and demonstrate multispectral, real-time short-wavelength Infrared in-vivo imaging.
Jesse Kohl - One of the best experts on this subject based on the ideXlab platform.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Brian A. Wall, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique.
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Rare-earth-doped biological composites as in vivo shortwave Infrared reporters
Nature Communications, 2013Co-Authors: Dominik J. Naczynski, Mei Chee Tan, Margot Zevon, Jesse Kohl, Anthony Kulesa, Suzie Chen, Charles M. Roth, Richard E. Riman, B. Wall, Prabhas MogheAbstract:The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that display data in real-time. Recent work suggests that a new window across the short-wavelength Infrared region can improve in vivo imaging sensitivity over near Infrared light. Here we report on the first evidence of multispectral, real-time short-wavelength Infrared imaging offering anatomical resolution using brightly emitting rare-earth nanomaterials and demonstrate their applicability toward disease-targeted imaging. Inorganic-protein nanocomposites of rare-earth nanomaterials with human serum albumin facilitated systemic biodistribution of the rare-earth nanomaterials resulting in the increased accumulation and retention in tumour tissue that was visualized by the localized enhancement of Infrared Signal Intensity. Our findings lay the groundwork for a new generation of versatile, biomedical nanomaterials that can advance disease monitoring based on a pioneering Infrared imaging technique. The short-wavelength Infrared spectral region is of interest for bio-imaging applications as biological tissue is transparent to such light. Here Naczynski et al . fabricate rare-earth-based nanomaterials and demonstrate multispectral, real-time short-wavelength Infrared in-vivo imaging.