The Experts below are selected from a list of 57906 Experts worldwide ranked by ideXlab platform

R L Sammons - One of the best experts on this subject based on the ideXlab platform.

  • stereo imaging and cytocompatibility of a model dental implant surface formed by direct laser fabrication
    Journal of Biomedical Materials Research Part A, 2009
    Co-Authors: Carlo Mangano, Mario Raspanti, Tonino Traini, Adriano Piattelli, R L Sammons
    Abstract:

    Direct laser fabrication (DLF) allows solids with complex geometry to be produced by sintering metal powder particles in a focused laser beam. In this study, 10 Ti6Al4V alloy model dental root implants were obtained by DLF, and surface characterization was carried out using stereo scanning electron microscopy to produce 3D reconstructions. The surfaces were extremely irregular, with ∼100 μm deep, narrow intercommunicating crevices, shallow depressions and deep, rounded pits of widely variable shape and size, showing ample scope for interlocking with the host bone. Roughness parameters were as follows: Rt, 360.8 μm; Rz, 358.4 μm; Ra, 67.4 μm; and Rq, 78.0 μm. Disc specimens produced by DLF with an identically prepared surface were used for biocompatibility studies with rat calvarial osteoblasts: After 9 days, cells had attached and spread on the DLF surface, spanning across the crevices, and voids. Cell density was similar to that on a commercial rough microtextured surface but lower than on commercial smooth machined and smooth-textured grit-blasted, Acid-etched surfaces. Human fibrin clot extension on the DLF surface was slightly improved by Inorganic Acid etching to increase the microroughness. With further refinements, DLF could be an economical means of manufacturing implants from titanium alloys. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res, 2009

  • stereo imaging and cytocompatibility of a model dental implant surface formed by direct laser fabrication
    Journal of Biomedical Materials Research Part A, 2009
    Co-Authors: Carlo Mangano, Mario Raspanti, Tonino Traini, Adriano Piattelli, R L Sammons
    Abstract:

    Direct laser fabrication (DLF) allows solids with complex geometry to be produced by sintering metal powder particles in a focused laser beam. In this study, 10 Ti6Al4V alloy model dental root implants were obtained by DLF, and surface characterization was carried out using stereo scanning electron microscopy to produce 3D reconstructions. The surfaces were extremely irregular, with approximately 100 microm deep, narrow intercommunicating crevices, shallow depressions and deep, rounded pits of widely variable shape and size, showing ample scope for interlocking with the host bone. Roughness parameters were as follows: R(t), 360.8 microm; R(z), 358.4 microm; R(a), 67.4 microm; and R(q), 78.0 microm. Disc specimens produced by DLF with an identically prepared surface were used for biocompatibility studies with rat calvarial osteoblasts: After 9 days, cells had attached and spread on the DLF surface, spanning across the crevices, and voids. Cell density was similar to that on a commercial rough microtextured surface but lower than on commercial smooth machined and smooth-textured grit-blasted, Acid-etched surfaces. Human fibrin clot extension on the DLF surface was slightly improved by Inorganic Acid etching to increase the microroughness. With further refinements, DLF could be an economical means of manufacturing implants from titanium alloys.

David Zaridze - One of the best experts on this subject based on the ideXlab platform.

  • occupational exposure and laryngeal and hypopharyngeal cancer risk in central and eastern europe
    American Journal of Epidemiology, 2006
    Co-Authors: Oxana Shangina, Paul Brennan, Paolo Boffetta, Neonila Szeszeniadabrowska, Dana Mates, Eleonora Fabianova, Tony Fletcher, A Tmannetje, David Zaridze
    Abstract:

    A multicenter case-control study was conducted during 1999-2002 in four European countries (Poland, Romania, Russia, and Slovakia) to evaluate the role of occupational exposures in risk of laryngeal/hypopharyngeal cancer. Male cancer cases (34 hypopharyngeal, 316 laryngeal) with full data on occupational history and nonoccupational factors were compared with 728 hospital controls for occupational exposure to 73 suspected carcinogens. Occupational history was evaluated by industrial hygienists blinded to case/control status. Elevated risks for ever exposure to coal dust were found for both hypopharyngeal (odds ratio (OR) = 4.19, 95% confidence interval (CI): 1.18, 14.89) and laryngeal (OR = 1.81, 95% CI: 0.94, 3.47) cancer, with clear dose-response patterns. Inclusion of a 20-year lag in the analysis strengthened these associations. Hypopharyngeal cancer risk was also significantly associated with exposure to mild steel dust (OR = 3.04, 95% CI: 1.39, 6.64) and iron compounds and fumes (OR = 2.74, 95% CI: 1.29, 5.84), without clear dose-response relations. Laryngeal cancer was significantly associated with exposure to hard-alloys dust (OR = 2.23, 95% CI: 1.08, 4.57) and chlorinated solvents (OR = 2.18, 95% CI: 1.03, 4.61), without dose-response relations. A possible link between high formaldehyde exposure and laryngeal cancer was suggested. No association was found for exposure to asbestos or Inorganic Acid mists. These data indicate that occupational exposure to coal dust may play a role in laryngeal and hypopharyngeal cancer. Other possible relations need further evaluation.

  • occupational exposure and laryngeal and hypopharyngeal cancer risk in central and eastern europe
    American Journal of Epidemiology, 2006
    Co-Authors: Oxana Shangina, Paul Brennan, Paolo Boffetta, Neonila Szeszeniadabrowska, Dana Mates, Eleonora Fabianova, Tony Fletcher, A Tmannetje, David Zaridze
    Abstract:

    A multicenter case-control study was conducted during 1999-2002 in four European countries (Poland, Romania, Russia, and Slovakia) to evaluate the role of occupational exposures in risk of laryngeal/hypopharyngeal cancer. Male cancer cases (34 hypopharyngeal, 316 laryngeal) with full data on occupational history and nonoccupational factors were compared with 728 hospital controls for occupational exposure to 73 suspected carcinogens. Occupational history was evaluated by industrial hygienists blinded to case/control status. Elevated risks for ever exposure to coal dust were found for both hypopharyngeal (odds ratio (OR) = 4.19, 95% confidence interval (CI): 1.18, 14.89) and laryngeal (OR = 1.81, 95% CI: 0.94, 3.47) cancer, with clear dose-response patterns. Inclusion of a 20-year lag in the analysis strengthened these associations. Hypopharyngeal cancer risk was also significantly associated with exposure to mild steel dust (OR = 3.04, 95% CI: 1.39, 6.64) and iron compounds and fumes (OR = 2.74, 95% CI: 1.29, 5.84), without clear dose-response relations. Laryngeal cancer was significantly associated with exposure to hard-alloys dust (OR = 2.23, 95% CI: 1.08, 4.57) and chlorinated solvents (OR = 2.18, 95% CI: 1.03, 4.61), without dose-response relations. A possible link between high formaldehyde exposure and laryngeal cancer was suggested. No association was found for exposure to asbestos or Inorganic Acid mists. These data indicate that occupational exposure to coal dust may play a role in laryngeal and hypopharyngeal cancer. Other possible relations need further evaluation.

Carlo Mangano - One of the best experts on this subject based on the ideXlab platform.

  • stereo imaging and cytocompatibility of a model dental implant surface formed by direct laser fabrication
    Journal of Biomedical Materials Research Part A, 2009
    Co-Authors: Carlo Mangano, Mario Raspanti, Tonino Traini, Adriano Piattelli, R L Sammons
    Abstract:

    Direct laser fabrication (DLF) allows solids with complex geometry to be produced by sintering metal powder particles in a focused laser beam. In this study, 10 Ti6Al4V alloy model dental root implants were obtained by DLF, and surface characterization was carried out using stereo scanning electron microscopy to produce 3D reconstructions. The surfaces were extremely irregular, with ∼100 μm deep, narrow intercommunicating crevices, shallow depressions and deep, rounded pits of widely variable shape and size, showing ample scope for interlocking with the host bone. Roughness parameters were as follows: Rt, 360.8 μm; Rz, 358.4 μm; Ra, 67.4 μm; and Rq, 78.0 μm. Disc specimens produced by DLF with an identically prepared surface were used for biocompatibility studies with rat calvarial osteoblasts: After 9 days, cells had attached and spread on the DLF surface, spanning across the crevices, and voids. Cell density was similar to that on a commercial rough microtextured surface but lower than on commercial smooth machined and smooth-textured grit-blasted, Acid-etched surfaces. Human fibrin clot extension on the DLF surface was slightly improved by Inorganic Acid etching to increase the microroughness. With further refinements, DLF could be an economical means of manufacturing implants from titanium alloys. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res, 2009

  • stereo imaging and cytocompatibility of a model dental implant surface formed by direct laser fabrication
    Journal of Biomedical Materials Research Part A, 2009
    Co-Authors: Carlo Mangano, Mario Raspanti, Tonino Traini, Adriano Piattelli, R L Sammons
    Abstract:

    Direct laser fabrication (DLF) allows solids with complex geometry to be produced by sintering metal powder particles in a focused laser beam. In this study, 10 Ti6Al4V alloy model dental root implants were obtained by DLF, and surface characterization was carried out using stereo scanning electron microscopy to produce 3D reconstructions. The surfaces were extremely irregular, with approximately 100 microm deep, narrow intercommunicating crevices, shallow depressions and deep, rounded pits of widely variable shape and size, showing ample scope for interlocking with the host bone. Roughness parameters were as follows: R(t), 360.8 microm; R(z), 358.4 microm; R(a), 67.4 microm; and R(q), 78.0 microm. Disc specimens produced by DLF with an identically prepared surface were used for biocompatibility studies with rat calvarial osteoblasts: After 9 days, cells had attached and spread on the DLF surface, spanning across the crevices, and voids. Cell density was similar to that on a commercial rough microtextured surface but lower than on commercial smooth machined and smooth-textured grit-blasted, Acid-etched surfaces. Human fibrin clot extension on the DLF surface was slightly improved by Inorganic Acid etching to increase the microroughness. With further refinements, DLF could be an economical means of manufacturing implants from titanium alloys.

Oxana Shangina - One of the best experts on this subject based on the ideXlab platform.

  • occupational exposure and laryngeal and hypopharyngeal cancer risk in central and eastern europe
    American Journal of Epidemiology, 2006
    Co-Authors: Oxana Shangina, Paul Brennan, Paolo Boffetta, Neonila Szeszeniadabrowska, Dana Mates, Eleonora Fabianova, Tony Fletcher, A Tmannetje, David Zaridze
    Abstract:

    A multicenter case-control study was conducted during 1999-2002 in four European countries (Poland, Romania, Russia, and Slovakia) to evaluate the role of occupational exposures in risk of laryngeal/hypopharyngeal cancer. Male cancer cases (34 hypopharyngeal, 316 laryngeal) with full data on occupational history and nonoccupational factors were compared with 728 hospital controls for occupational exposure to 73 suspected carcinogens. Occupational history was evaluated by industrial hygienists blinded to case/control status. Elevated risks for ever exposure to coal dust were found for both hypopharyngeal (odds ratio (OR) = 4.19, 95% confidence interval (CI): 1.18, 14.89) and laryngeal (OR = 1.81, 95% CI: 0.94, 3.47) cancer, with clear dose-response patterns. Inclusion of a 20-year lag in the analysis strengthened these associations. Hypopharyngeal cancer risk was also significantly associated with exposure to mild steel dust (OR = 3.04, 95% CI: 1.39, 6.64) and iron compounds and fumes (OR = 2.74, 95% CI: 1.29, 5.84), without clear dose-response relations. Laryngeal cancer was significantly associated with exposure to hard-alloys dust (OR = 2.23, 95% CI: 1.08, 4.57) and chlorinated solvents (OR = 2.18, 95% CI: 1.03, 4.61), without dose-response relations. A possible link between high formaldehyde exposure and laryngeal cancer was suggested. No association was found for exposure to asbestos or Inorganic Acid mists. These data indicate that occupational exposure to coal dust may play a role in laryngeal and hypopharyngeal cancer. Other possible relations need further evaluation.

  • occupational exposure and laryngeal and hypopharyngeal cancer risk in central and eastern europe
    American Journal of Epidemiology, 2006
    Co-Authors: Oxana Shangina, Paul Brennan, Paolo Boffetta, Neonila Szeszeniadabrowska, Dana Mates, Eleonora Fabianova, Tony Fletcher, A Tmannetje, David Zaridze
    Abstract:

    A multicenter case-control study was conducted during 1999-2002 in four European countries (Poland, Romania, Russia, and Slovakia) to evaluate the role of occupational exposures in risk of laryngeal/hypopharyngeal cancer. Male cancer cases (34 hypopharyngeal, 316 laryngeal) with full data on occupational history and nonoccupational factors were compared with 728 hospital controls for occupational exposure to 73 suspected carcinogens. Occupational history was evaluated by industrial hygienists blinded to case/control status. Elevated risks for ever exposure to coal dust were found for both hypopharyngeal (odds ratio (OR) = 4.19, 95% confidence interval (CI): 1.18, 14.89) and laryngeal (OR = 1.81, 95% CI: 0.94, 3.47) cancer, with clear dose-response patterns. Inclusion of a 20-year lag in the analysis strengthened these associations. Hypopharyngeal cancer risk was also significantly associated with exposure to mild steel dust (OR = 3.04, 95% CI: 1.39, 6.64) and iron compounds and fumes (OR = 2.74, 95% CI: 1.29, 5.84), without clear dose-response relations. Laryngeal cancer was significantly associated with exposure to hard-alloys dust (OR = 2.23, 95% CI: 1.08, 4.57) and chlorinated solvents (OR = 2.18, 95% CI: 1.03, 4.61), without dose-response relations. A possible link between high formaldehyde exposure and laryngeal cancer was suggested. No association was found for exposure to asbestos or Inorganic Acid mists. These data indicate that occupational exposure to coal dust may play a role in laryngeal and hypopharyngeal cancer. Other possible relations need further evaluation.

Mario Raspanti - One of the best experts on this subject based on the ideXlab platform.

  • stereo imaging and cytocompatibility of a model dental implant surface formed by direct laser fabrication
    Journal of Biomedical Materials Research Part A, 2009
    Co-Authors: Carlo Mangano, Mario Raspanti, Tonino Traini, Adriano Piattelli, R L Sammons
    Abstract:

    Direct laser fabrication (DLF) allows solids with complex geometry to be produced by sintering metal powder particles in a focused laser beam. In this study, 10 Ti6Al4V alloy model dental root implants were obtained by DLF, and surface characterization was carried out using stereo scanning electron microscopy to produce 3D reconstructions. The surfaces were extremely irregular, with ∼100 μm deep, narrow intercommunicating crevices, shallow depressions and deep, rounded pits of widely variable shape and size, showing ample scope for interlocking with the host bone. Roughness parameters were as follows: Rt, 360.8 μm; Rz, 358.4 μm; Ra, 67.4 μm; and Rq, 78.0 μm. Disc specimens produced by DLF with an identically prepared surface were used for biocompatibility studies with rat calvarial osteoblasts: After 9 days, cells had attached and spread on the DLF surface, spanning across the crevices, and voids. Cell density was similar to that on a commercial rough microtextured surface but lower than on commercial smooth machined and smooth-textured grit-blasted, Acid-etched surfaces. Human fibrin clot extension on the DLF surface was slightly improved by Inorganic Acid etching to increase the microroughness. With further refinements, DLF could be an economical means of manufacturing implants from titanium alloys. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res, 2009

  • stereo imaging and cytocompatibility of a model dental implant surface formed by direct laser fabrication
    Journal of Biomedical Materials Research Part A, 2009
    Co-Authors: Carlo Mangano, Mario Raspanti, Tonino Traini, Adriano Piattelli, R L Sammons
    Abstract:

    Direct laser fabrication (DLF) allows solids with complex geometry to be produced by sintering metal powder particles in a focused laser beam. In this study, 10 Ti6Al4V alloy model dental root implants were obtained by DLF, and surface characterization was carried out using stereo scanning electron microscopy to produce 3D reconstructions. The surfaces were extremely irregular, with approximately 100 microm deep, narrow intercommunicating crevices, shallow depressions and deep, rounded pits of widely variable shape and size, showing ample scope for interlocking with the host bone. Roughness parameters were as follows: R(t), 360.8 microm; R(z), 358.4 microm; R(a), 67.4 microm; and R(q), 78.0 microm. Disc specimens produced by DLF with an identically prepared surface were used for biocompatibility studies with rat calvarial osteoblasts: After 9 days, cells had attached and spread on the DLF surface, spanning across the crevices, and voids. Cell density was similar to that on a commercial rough microtextured surface but lower than on commercial smooth machined and smooth-textured grit-blasted, Acid-etched surfaces. Human fibrin clot extension on the DLF surface was slightly improved by Inorganic Acid etching to increase the microroughness. With further refinements, DLF could be an economical means of manufacturing implants from titanium alloys.