The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform
Jun Liu - One of the best experts on this subject based on the ideXlab platform.
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Midbrain/pons area ratio and clinical features predict the prognosis of progressive Supranuclear palsy
BMC neurology, 2020Co-Authors: Shi-shuang Cui, Hua-wei Ling, Yi-qi Lin, Jing Pan, Hai-yan Zhou, Gang Wang, Ying Wang, Qin Xiao, Jun LiuAbstract:Progressive supranuclear palsy (PSP) is a rare movement disorder with poor prognosis. This retrospective study aimed to characterize the natural history of PSP and to find predictors of shorter survival and faster decline of activity of daily living. All patients recruited fulfilled the movement disorder society (MDS) clinical diagnostic criteria for PSP (MDS-PSP criteria) for probable and possible PSP with median 12 years. Data were obtained including age, sex, date of onset, age at onset (AAO), symptoms reported at first visit and follow-up, date of death and date of Institutionalization. Magnetic resonance imaging was collected at the first visit. Endpoints were death and Institutionalization. Kaplan-Meier method and Cox proportional hazard model were used to explore factors associated with early death and Institutionalization. Fifty-nine patients fulfilling MDS-PSP criteria were enrolled in our study. Nineteen patients (32.2%) had died and 31 patients (52.5%) were institutionalized by the end of the follow-up. Predictors associated with poorer survival were late-onset PSP and decreased M/P area ratio. Predictors associated with earlier Institutionalization were older AAO and decreased M/P area ratio. Older AAO and decreased M/P area ratio were predictors for earlier dearth and Institutionalization in PSP. The neuroimaging biomarker M/P area ratio was a predictor for prognosis in PSP.
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Midbrain/pons area ratio and clinical features predict the prognosis of Progressive Supranuclear Palsy
2020Co-Authors: Shi-shuang Cui, Hua-wei Ling, Yi-qi Lin, Jing Pan, Hai-yan Zhou, Gang Wang, Ying Wang, Qin Xiao, Jun LiuAbstract:Abstract Backgrounds: Progressive Supranuclear Palsy (PSP) is a rare movement disorder with poor prognosis. This retrospective study aims to characterize the natural history of PSP and to find predictors of shorter survival and faster decline of activity of daily living. Method: All patients recruited fulfilled the movement disorder society (MDS) clinical diagnostic criteria for PSP (MDS-PSP criteria) for probable and possible PSP with median 12 years. Data were obtained including age, sex, date of onset, age at onset (AAO), symptoms reported at first visit and follow-up, date of death and date of Institutionalization. Magnetic resonance imaging was collected at the first visit. Endpoints were death and Institutionalization. Kaplan-Meier method and Cox proportional hazard model were used to explore factors associated with early death and Institutionalization. Results: 59 patients fulfilling MDS-PSP criteria were enrolled in our study. 19 patients (32.2%) had died and 31 patients (52.5%) were institutionalizedl by the end of the follow-up. Predictors associated with poorer survival were late-onset PSP and decreased M/P area ratio. Predictors associated with earlier Institutionalization were older AAO and decreased M/P area ratio. Conclusion: older and decreased M/P area ratio were predictors for earlier dearth and Institutionalization in PSP. The neuroimaging biomarker M/P area ratio was a predictor for prognosis in PSP.
Matti Viitanen - One of the best experts on this subject based on the ideXlab platform.
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Factors associated with Institutionalization among home-dwelling patients of Urgent Geriatric Outpatient Clinic: a 3-year follow-up study
European Geriatric Medicine, 2020Co-Authors: Marika Salminen, Jonna Laine, Paula Viikari, Maarit Wuorela, Matti Viitanen, Tero Vahlberg, Laura ViikariAbstract:Aim To examine the effect of predictive factors on Institutionalization among home-dwelling patients of Urgent Geriatric Outpatient Clinic during a 3-year follow-up. Findings The rates of Institutionalization and mortality were 29.9% and 46.1%, respectively. The use of home care, dementia, higher age and falls during the previous 12 months significantly predicted Institutionalization during the follow-up. Message Cognitive and/or functional impairment mainly predicted Institutionalization among older patients of UrGeriC having health problems and acute difficulties in managing at home. Purpose To examine the effect of predictive factors on Institutionalization among older patients. Methods The participants were older (aged 75 years or older) home-dwelling citizens evaluated at Urgent Geriatric Outpatient Clinic (UrGeriC) for the first time between the 1st of September 2013 and the 1st of September 2014 ( n = 1300). They were followed up for Institutionalization for 3 years. Death was used as a competing risk in Cox regression analyses. Results The mean age of the participants was 85.1 years (standard deviation [SD] 5.5, range 75–103 years), and 74% were female. The rates of Institutionalization and mortality were 29.9% and 46.1%, respectively. The mean age for Institutionalization was 86.1 (SD 5.6) years. According to multivariate Cox regression analyses, the use of home care (hazard ratio 2.43, 95% confidence interval 1.80–3.27, p
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Factors associated with Institutionalization among home-dwelling patients of Urgent Geriatric Outpatient Clinic: a 3-year follow-up study
European Geriatric Medicine, 2020Co-Authors: Marika Salminen, Jonna Laine, Paula Viikari, Maarit Wuorela, Matti Viitanen, Tero Vahlberg, Laura ViikariAbstract:Purpose To examine the effect of predictive factors on Institutionalization among older patients. Methods The participants were older (aged 75 years or older) home-dwelling citizens evaluated at Urgent Geriatric Outpatient Clinic (UrGeriC) for the first time between the 1st of September 2013 and the 1st of September 2014 ( n = 1300). They were followed up for Institutionalization for 3 years. Death was used as a competing risk in Cox regression analyses. Results The mean age of the participants was 85.1 years (standard deviation [SD] 5.5, range 75–103 years), and 74% were female. The rates of Institutionalization and mortality were 29.9% and 46.1%, respectively. The mean age for Institutionalization was 86.1 (SD 5.6) years. According to multivariate Cox regression analyses, the use of home care (hazard ratio 2.43, 95% confidence interval 1.80–3.27, p
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Institutionalization in the elderly the role of chronic diseases and dementia cross sectional and longitudinal data from a population based study
Journal of Clinical Epidemiology, 2001Co-Authors: Hedda Aguerotorres, Matti Viitanen, Eva Von Strauss, Bengt Winblad, Laura FratiglioniAbstract:A population-based study of 1810 persons, aged 75+, was investigated to evaluate the role of dementia and other chronic diseases as determinants of Institutionalization in the elderly. The study population was examined at baseline and after a 3-year interval. After adjustment for sociodemographic characteristics, functional dependence, dementia, cerebrovascular disease and hip fracture were associated with living in an institution at baseline. Additionally, functional dependence, hip fracture and dementia were also associated with moving to an institution during the 3-year follow-up. In a similar analysis, including only nondemented subjects, the Mini-Mental State Examination emerged as one of the strongest determinants. The population attributable risk percentage of Institutionalization during the 3-year follow-up due to dementia was 61%. This study confirms that dementia and cognitive impairment are the main contributors to Institutionalization in the elderly, independently of their sociodemographic status, social network, or functional status.
Shi-shuang Cui - One of the best experts on this subject based on the ideXlab platform.
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Midbrain/pons area ratio and clinical features predict the prognosis of progressive Supranuclear palsy
BMC neurology, 2020Co-Authors: Shi-shuang Cui, Hua-wei Ling, Yi-qi Lin, Jing Pan, Hai-yan Zhou, Gang Wang, Ying Wang, Qin Xiao, Jun LiuAbstract:Progressive supranuclear palsy (PSP) is a rare movement disorder with poor prognosis. This retrospective study aimed to characterize the natural history of PSP and to find predictors of shorter survival and faster decline of activity of daily living. All patients recruited fulfilled the movement disorder society (MDS) clinical diagnostic criteria for PSP (MDS-PSP criteria) for probable and possible PSP with median 12 years. Data were obtained including age, sex, date of onset, age at onset (AAO), symptoms reported at first visit and follow-up, date of death and date of Institutionalization. Magnetic resonance imaging was collected at the first visit. Endpoints were death and Institutionalization. Kaplan-Meier method and Cox proportional hazard model were used to explore factors associated with early death and Institutionalization. Fifty-nine patients fulfilling MDS-PSP criteria were enrolled in our study. Nineteen patients (32.2%) had died and 31 patients (52.5%) were institutionalized by the end of the follow-up. Predictors associated with poorer survival were late-onset PSP and decreased M/P area ratio. Predictors associated with earlier Institutionalization were older AAO and decreased M/P area ratio. Older AAO and decreased M/P area ratio were predictors for earlier dearth and Institutionalization in PSP. The neuroimaging biomarker M/P area ratio was a predictor for prognosis in PSP.
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Midbrain/pons area ratio and clinical features predict the prognosis of Progressive Supranuclear Palsy
2020Co-Authors: Shi-shuang Cui, Hua-wei Ling, Yi-qi Lin, Jing Pan, Hai-yan Zhou, Gang Wang, Ying Wang, Qin Xiao, Jun LiuAbstract:Abstract Backgrounds: Progressive Supranuclear Palsy (PSP) is a rare movement disorder with poor prognosis. This retrospective study aims to characterize the natural history of PSP and to find predictors of shorter survival and faster decline of activity of daily living. Method: All patients recruited fulfilled the movement disorder society (MDS) clinical diagnostic criteria for PSP (MDS-PSP criteria) for probable and possible PSP with median 12 years. Data were obtained including age, sex, date of onset, age at onset (AAO), symptoms reported at first visit and follow-up, date of death and date of Institutionalization. Magnetic resonance imaging was collected at the first visit. Endpoints were death and Institutionalization. Kaplan-Meier method and Cox proportional hazard model were used to explore factors associated with early death and Institutionalization. Results: 59 patients fulfilling MDS-PSP criteria were enrolled in our study. 19 patients (32.2%) had died and 31 patients (52.5%) were institutionalizedl by the end of the follow-up. Predictors associated with poorer survival were late-onset PSP and decreased M/P area ratio. Predictors associated with earlier Institutionalization were older AAO and decreased M/P area ratio. Conclusion: older and decreased M/P area ratio were predictors for earlier dearth and Institutionalization in PSP. The neuroimaging biomarker M/P area ratio was a predictor for prognosis in PSP.
A. Teodorescu - One of the best experts on this subject based on the ideXlab platform.
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Institutionalization of patients with schizophrenia in the modern era
European Psychiatry, 2016Co-Authors: Petru Ifteni, Andreea Silvana Szalontay, A. TeodorescuAbstract:Introduction Patients with schizophrenia requiring long-term Institutionalization represent cases with poor outcome, often leading to high costs for patients and family and constituting a huge economical burden for society if patients are young. Aims The aims were the evaluation of patient hospitalized for long period in a psychiatric hospital for chronic patients. Objectives The objectives of the study were identification of characteristics and predictors of Institutionalization in schizophrenia. Methods Retrospective study of all institutionalized patients with schizophrenia in Brasov County, Romania, with a DSM-IV-TR lifetime diagnosis of schizophrenia institutionalized between 1995 and 2014. Results Institutionalized patients between 2005 and 2014 (n = 172) had lower age (51.15 vs. 57.08, P Conclusions Our study showed a tendency to institutionalize patients with schizophrenia at the younger age compared with past decades. Early intervention in psychosis, controlled treatment with SGAs should be solutions to avoid Institutionalization of young patients with schizophrenia.
Gang Wang - One of the best experts on this subject based on the ideXlab platform.
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Midbrain/pons area ratio and clinical features predict the prognosis of progressive Supranuclear palsy
BMC neurology, 2020Co-Authors: Shi-shuang Cui, Hua-wei Ling, Yi-qi Lin, Jing Pan, Hai-yan Zhou, Gang Wang, Ying Wang, Qin Xiao, Jun LiuAbstract:Progressive supranuclear palsy (PSP) is a rare movement disorder with poor prognosis. This retrospective study aimed to characterize the natural history of PSP and to find predictors of shorter survival and faster decline of activity of daily living. All patients recruited fulfilled the movement disorder society (MDS) clinical diagnostic criteria for PSP (MDS-PSP criteria) for probable and possible PSP with median 12 years. Data were obtained including age, sex, date of onset, age at onset (AAO), symptoms reported at first visit and follow-up, date of death and date of Institutionalization. Magnetic resonance imaging was collected at the first visit. Endpoints were death and Institutionalization. Kaplan-Meier method and Cox proportional hazard model were used to explore factors associated with early death and Institutionalization. Fifty-nine patients fulfilling MDS-PSP criteria were enrolled in our study. Nineteen patients (32.2%) had died and 31 patients (52.5%) were institutionalized by the end of the follow-up. Predictors associated with poorer survival were late-onset PSP and decreased M/P area ratio. Predictors associated with earlier Institutionalization were older AAO and decreased M/P area ratio. Older AAO and decreased M/P area ratio were predictors for earlier dearth and Institutionalization in PSP. The neuroimaging biomarker M/P area ratio was a predictor for prognosis in PSP.
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Midbrain/pons area ratio and clinical features predict the prognosis of Progressive Supranuclear Palsy
2020Co-Authors: Shi-shuang Cui, Hua-wei Ling, Yi-qi Lin, Jing Pan, Hai-yan Zhou, Gang Wang, Ying Wang, Qin Xiao, Jun LiuAbstract:Abstract Backgrounds: Progressive Supranuclear Palsy (PSP) is a rare movement disorder with poor prognosis. This retrospective study aims to characterize the natural history of PSP and to find predictors of shorter survival and faster decline of activity of daily living. Method: All patients recruited fulfilled the movement disorder society (MDS) clinical diagnostic criteria for PSP (MDS-PSP criteria) for probable and possible PSP with median 12 years. Data were obtained including age, sex, date of onset, age at onset (AAO), symptoms reported at first visit and follow-up, date of death and date of Institutionalization. Magnetic resonance imaging was collected at the first visit. Endpoints were death and Institutionalization. Kaplan-Meier method and Cox proportional hazard model were used to explore factors associated with early death and Institutionalization. Results: 59 patients fulfilling MDS-PSP criteria were enrolled in our study. 19 patients (32.2%) had died and 31 patients (52.5%) were institutionalizedl by the end of the follow-up. Predictors associated with poorer survival were late-onset PSP and decreased M/P area ratio. Predictors associated with earlier Institutionalization were older AAO and decreased M/P area ratio. Conclusion: older and decreased M/P area ratio were predictors for earlier dearth and Institutionalization in PSP. The neuroimaging biomarker M/P area ratio was a predictor for prognosis in PSP.
