The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Alice Bloch - One of the best experts on this subject based on the ideXlab platform.
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refugees in the uk labour market the conflict between economic Integration and policy led labour market restriction
Journal of Social Policy, 2008Co-Authors: Alice BlochAbstract:This article draws on data from a survey of 400 refugees and shows low levels of labour market activity. The minority of refugees who are working are in secondary sector jobs with little opportunity for progression.Moreover, refugees with high levels of skills who are working are not in jobs commensurate with their skills and qualifications. The article examines the human capacity and personal characteristics that have an impact on refugee employment, and finds the greatest difference in employment is between men and women, although English language fluency and training are also very important. Employment is a major part of the refugee Integration Strategy, and employment initiatives focus on capacity- uilding rather than discrimination or reversing restrictive policies. The article concludes that strategies need to focus on individual employability as well as measures to overcome personal and structural barriers to the labour market.
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refugees in the uk labour market the conflict between economic Integration and policy led labour market restriction
Journal of Social Policy, 2008Co-Authors: Alice BlochAbstract:This article draws on data from a survey of 400 refugees and shows low levels of labour market activity. The minority of refugees who are working are in secondary sector jobs with little opportunity for progression.Moreover, refugees with high levels of skills who are working are not in jobs commensurate with their skills and qualifications. The article examines the human capacity and personal characteristics that have an impact on refugee employment, and finds the greatest difference in employment is between men and women, although English language fluency and training are also very important. Employment is a major part of the refugee Integration Strategy, and employment initiatives focus on capacity- uilding rather than discrimination or reversing restrictive policies. The article concludes that strategies need to focus on individual employability as well as measures to overcome personal and structural barriers to the labour market.
Nancy M Heddle - One of the best experts on this subject based on the ideXlab platform.
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a decision Integration Strategy for short term demand forecasting and ordering for red blood cell components
Operations research for health care, 2021Co-Authors: Fei Chiang, Douglas G Down, Nancy M HeddleAbstract:Abstract Blood transfusion is one of the most crucial and commonly administered therapeutics worldwide. The need for more accurate and efficient ways to manage blood demand and supply is an increasing concern. Building a technology-based, robust blood demand and supply chain that can achieve the goals of reducing ordering frequency, inventory level, wastage and shortage, while maintaining the safety of blood usage, is essential in modern healthcare systems. In this study, we summarize the key challenges in current demand and supply management for red blood cells (RBCs). We combine ideas from statistical time series modeling, machine learning, and operations research in developing an ordering decision Strategy for RBCs, through integrating a hybrid demand forecasting model using clinical predictors and a data-driven multi-period inventory problem considering inventory and reorder constraints. We have applied the integrated ordering Strategy to the blood inventory management system in Hamilton, Ontario using a large clinical database from 2008 to 2018. The proposed hybrid demand forecasting model provides robust and accurate predictions, and identifies important clinical predictors for short-term RBC demand forecasting. Compared with the actual historical data, our integrated ordering Strategy reduces the inventory level by 40% and decreases the ordering frequency by 60%, with low incidence of shortages and wastage due to expiration. If implemented successfully, our proposed Strategy can achieve significant cost savings for healthcare systems and blood suppliers. The proposed ordering Strategy is generalizable to other blood products or even other perishable products.
Jhuma Sadhukhan - One of the best experts on this subject based on the ideXlab platform.
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Heat Integration Strategy for Economic Production of Combined Heat and Power from Biomass Waste
Energy & Fuels, 2009Co-Authors: Jhuma Sadhukhan, Kok Siew Ng, Nilay Shah, Howard J. SimonsAbstract:The objective of this work was to design a heat integrated, cost-effective, and cleaner combined heat and power (CHP) generation plant from low-cost, fourth-generation biomass waste feedstocks. The novelty lies in the development of systematic sitewide heat recovery and Integration strategies among biomass integrated gasification combined cycle processes so as to offset the low heating value of the biomass waste feedstocks. For the biomass waste based CHP plant technical and economic analysis, the process was based on low-cost agricultural wastes like straws as the biomass feedstock and further established for a more predominant biomass feedstock, wood. The process was modeled using the Aspen simulator. Three conceptual flowsheets were proposed, based on the Integration of the flue gas from the char combustor, which was separately carried out from the steam gasification of biomass volatalized gases and tars, and carbon dioxide removal strategies. The cost of energy production included detailed levelized d...
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heat Integration Strategy for economic production of combined heat and power from biomass waste
Energy & Fuels, 2009Co-Authors: Jhuma Sadhukhan, Nilay Shah, Howard J. SimonsAbstract:The objective of this work was to design a heat integrated, cost-effective, and cleaner combined heat and power (CHP) generation plant from low-cost, fourth-generation biomass waste feedstocks. The novelty lies in the development of systematic sitewide heat recovery and Integration strategies among biomass integrated gasification combined cycle processes so as to offset the low heating value of the biomass waste feedstocks. For the biomass waste based CHP plant technical and economic analysis, the process was based on low-cost agricultural wastes like straws as the biomass feedstock and further established for a more predominant biomass feedstock, wood. The process was modeled using the Aspen simulator. Three conceptual flowsheets were proposed, based on the Integration of the flue gas from the char combustor, which was separately carried out from the steam gasification of biomass volatalized gases and tars, and carbon dioxide removal strategies. The cost of energy production included detailed levelized discounted cash flow analysis and was found to be strongly influenced by the cost of feedstock. On the basis of a combined energy generation of 340−370 MW using straw wastes priced at 35.3 £/t or 40 Euro/t, with 8.5% and 8.61% by mass moisture and ash contents, respectively, the cost of electricity generation was 4.59 and 5.14 p/(kW h) for the cases without and with carbon capture respectively, with a 10% internal rate of return and 25 years of plant life. On the basis of the carbon capture value assigned by the Carbon Credits Trading scheme, a much constrained viable price of 22 £/t of such agricultural waste feedstocks for CHP generation was obtained, while up to 60 £/t of waste feedstocks can be economically viable under the UK Climate Change Levy, respectively.
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Integration Strategy of gasification technology a gateway to future refining
Industrial & Engineering Chemistry Research, 2002Co-Authors: Jhuma SadhukhanAbstract:Stricter environmental legislation on emissions, product qualities, and the increased availability of heavier and sourer crudes are the main driving forces for refineries to use gasification technologies for the “bottom of the barrel” disposal into production of hydrogen and clean energy. However, economic viability needs to be fully proven. This paper takes the challenge of integrating gasification to an overall refinery. To achieve this, a four stage optimization Strategy is developed. In the screening and scoping stage, the energy Integration opportunities are explored. In site level optimization, the overall Integration among refinery and gasification is considered to maximize the margin. In process level optimization, appropriate Integration among gasification, hydrogen, and utility systems is derived to minimize the investment. Finally, the simultaneous optimization of site and process levels is carried out to trade off between benefits and investment. By applying this methodology to a refinery case...
Howard J. Simons - One of the best experts on this subject based on the ideXlab platform.
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Heat Integration Strategy for Economic Production of Combined Heat and Power from Biomass Waste
Energy & Fuels, 2009Co-Authors: Jhuma Sadhukhan, Kok Siew Ng, Nilay Shah, Howard J. SimonsAbstract:The objective of this work was to design a heat integrated, cost-effective, and cleaner combined heat and power (CHP) generation plant from low-cost, fourth-generation biomass waste feedstocks. The novelty lies in the development of systematic sitewide heat recovery and Integration strategies among biomass integrated gasification combined cycle processes so as to offset the low heating value of the biomass waste feedstocks. For the biomass waste based CHP plant technical and economic analysis, the process was based on low-cost agricultural wastes like straws as the biomass feedstock and further established for a more predominant biomass feedstock, wood. The process was modeled using the Aspen simulator. Three conceptual flowsheets were proposed, based on the Integration of the flue gas from the char combustor, which was separately carried out from the steam gasification of biomass volatalized gases and tars, and carbon dioxide removal strategies. The cost of energy production included detailed levelized d...
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heat Integration Strategy for economic production of combined heat and power from biomass waste
Energy & Fuels, 2009Co-Authors: Jhuma Sadhukhan, Nilay Shah, Howard J. SimonsAbstract:The objective of this work was to design a heat integrated, cost-effective, and cleaner combined heat and power (CHP) generation plant from low-cost, fourth-generation biomass waste feedstocks. The novelty lies in the development of systematic sitewide heat recovery and Integration strategies among biomass integrated gasification combined cycle processes so as to offset the low heating value of the biomass waste feedstocks. For the biomass waste based CHP plant technical and economic analysis, the process was based on low-cost agricultural wastes like straws as the biomass feedstock and further established for a more predominant biomass feedstock, wood. The process was modeled using the Aspen simulator. Three conceptual flowsheets were proposed, based on the Integration of the flue gas from the char combustor, which was separately carried out from the steam gasification of biomass volatalized gases and tars, and carbon dioxide removal strategies. The cost of energy production included detailed levelized discounted cash flow analysis and was found to be strongly influenced by the cost of feedstock. On the basis of a combined energy generation of 340−370 MW using straw wastes priced at 35.3 £/t or 40 Euro/t, with 8.5% and 8.61% by mass moisture and ash contents, respectively, the cost of electricity generation was 4.59 and 5.14 p/(kW h) for the cases without and with carbon capture respectively, with a 10% internal rate of return and 25 years of plant life. On the basis of the carbon capture value assigned by the Carbon Credits Trading scheme, a much constrained viable price of 22 £/t of such agricultural waste feedstocks for CHP generation was obtained, while up to 60 £/t of waste feedstocks can be economically viable under the UK Climate Change Levy, respectively.
Weiying Lin - One of the best experts on this subject based on the ideXlab platform.
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a unique Integration Strategy for the rational design of optically tunable near infrared fluorophores
Accounts of Chemical Research, 2017Co-Authors: Hua Chen, Baoli Dong, Yonghe Tang, Weiying LinAbstract:ConspectusFluorescence imaging is a rapidly growing technique for noninvasive imaging of biological molecules and processes with high spatial and temporal resolution. For effective biological imaging, it is essential and important to develop robust fluorescent dyes, in particular, near-infrared (NIR) fluorescent dyes with favorable optical properties. Compared with the visible light emitting dyes, NIR dyes have relatively longer emission wavelengths (650–900 nm) with lower energy and are advantageous as imaging agents owing to the minimum photodamage of NIR light to biological samples, deep penetration into tissues, and low interference from autofluorescence of biomolecules. Although great efforts have been devoted to engineer NIR fluorophores, it is still very challenging to regulate their photophysical properties as they often lack optically tunable mechanisms, and this shortcoming considerably restricts the realization of their full potential. Consequently, the rational design of small-molecule optical...
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A Unique “Integration” Strategy for the Rational Design of Optically Tunable Near-Infrared Fluorophores
2017Co-Authors: Hua Chen, Baoli Dong, Yonghe Tang, Weiying LinAbstract:ConspectusFluorescence imaging is a rapidly growing technique for noninvasive imaging of biological molecules and processes with high spatial and temporal resolution. For effective biological imaging, it is essential and important to develop robust fluorescent dyes, in particular, near-infrared (NIR) fluorescent dyes with favorable optical properties. Compared with the visible light emitting dyes, NIR dyes have relatively longer emission wavelengths (650–900 nm) with lower energy and are advantageous as imaging agents owing to the minimum photodamage of NIR light to biological samples, deep penetration into tissues, and low interference from autofluorescence of biomolecules. Although great efforts have been devoted to engineer NIR fluorophores, it is still very challenging to regulate their photophysical properties as they often lack optically tunable mechanisms, and this shortcoming considerably restricts the realization of their full potential. Consequently, the rational design of small-molecule optically tunable NIR fluorophores is of high priority and great value.In general, two key characteristics are indispensable for designing excellent optically tunable NIR fluorescent dyes. First, NIR fluorescent dyes should display the maximal absorption and emission located in the NIR region and also have the prominent properties including excellent fluorescence quantum yields, large Stokes shifts, good chemical stability and photostability, low cytotoxicity, and desirable compatibility with biological systems. Second, in principle, functional NIR dyes should also possess optically tunable groups, which can be easily modified to afford responsive sites for the targets of interest.With these considerations in mind, in this Account, we described a unique “Integration” Strategy for judicious design of the optically tunable NIR fluorophores, which are an intuitive combination of the traditional NIR dyes and the optically tunable mechanisms in the visible light emissive dyes. Thus, the versatile Strategy may allow not only retention of the NIR emission properties of NIR dyes but also inheritance of the optically tunable mechanisms from the visible light emissive dyes. By the unique Integration Strategy, a built-in optically tunable group is strategically installed into the traditional NIR fluorescent dyes to directly tune their optical properties. Herein, we present a concise review of the rational design Strategy and biological applications of small-molecule optically tunable NIR fluorescent dyes via the unique Integration Strategy, and we focused mainly on our work and some representative examples from other groups based on our NIR platforms. This Account includes the detailed Integration Strategy of each class of the NIR fluorescent dyes, the development of their derivatives, and their imaging applications in living systems
