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Colin Royse - One of the best experts on this subject based on the ideXlab platform.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Mohamed M Ali, Colin RoyseAbstract:BACKGROUND Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Colin RoyseAbstract:BACKGROUND: Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS: In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS: Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION: Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
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shape and movement of the Interatrial Septum predicts change in pulmonary capillary wedge pressure
Annals of Thoracic and Cardiovascular Surgery, 2001Co-Authors: Colin Royse, Alistair Royse, Paul Soeding, D W BlakeAbstract:We aimed to assess whether movement of the Interatrial Septum predicts change in pulmonary capillary wedge pressure (PCWP). In 71 patients undergoing cardiac surgery, the Interatrial Septum was categorised by its shape and movement using transesophageal echocardiography. Fixed curvature (FC) was identified by bowing of the Interatrial Septum from left to right throughout the cardiac cycle, mid-systolic reversal (MSR) by minimal septal movement and transient reversal (right to left) during mid-systole, and mid-systolic buckling (MSB) by marked movement and buckling of the Septum during mid-systole. These were compared with PCWP. Sensitivity and interobserver reliability was studied with continuous PCWP and TEE measurement during a period of acute volume alteration in 10 additional patients. Interatrial septal movement predicted PCWP, with mean PCWP (95% confidence intervals) for FC, 18.1 mmHg (16.7 to 19.6), MSR 13.2 mmHg (12.5 to 13.8) and MSB, 9.9 mmHg (9.0 to 10.7) mmHg. The mean PCWP at which a change in pattern occurred was 8.9 mmHg (8.3 to 9.6) for MSR to MSB, and 10.9 mmHg (10.1 to 11.8) for MSR to FC (p<0.001). There was no significant difference in mean values for all three observers. Movement of the Interatrial Septum predicts change in PCWP.
Darsim Haji - One of the best experts on this subject based on the ideXlab platform.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Colin RoyseAbstract:BACKGROUND: Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS: In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS: Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION: Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Mohamed M Ali, Colin RoyseAbstract:BACKGROUND Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
Alistair Royse - One of the best experts on this subject based on the ideXlab platform.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Mohamed M Ali, Colin RoyseAbstract:BACKGROUND Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Colin RoyseAbstract:BACKGROUND: Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS: In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS: Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION: Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
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shape and movement of the Interatrial Septum predicts change in pulmonary capillary wedge pressure
Annals of Thoracic and Cardiovascular Surgery, 2001Co-Authors: Colin Royse, Alistair Royse, Paul Soeding, D W BlakeAbstract:We aimed to assess whether movement of the Interatrial Septum predicts change in pulmonary capillary wedge pressure (PCWP). In 71 patients undergoing cardiac surgery, the Interatrial Septum was categorised by its shape and movement using transesophageal echocardiography. Fixed curvature (FC) was identified by bowing of the Interatrial Septum from left to right throughout the cardiac cycle, mid-systolic reversal (MSR) by minimal septal movement and transient reversal (right to left) during mid-systole, and mid-systolic buckling (MSB) by marked movement and buckling of the Septum during mid-systole. These were compared with PCWP. Sensitivity and interobserver reliability was studied with continuous PCWP and TEE measurement during a period of acute volume alteration in 10 additional patients. Interatrial septal movement predicted PCWP, with mean PCWP (95% confidence intervals) for FC, 18.1 mmHg (16.7 to 19.6), MSR 13.2 mmHg (12.5 to 13.8) and MSB, 9.9 mmHg (9.0 to 10.7) mmHg. The mean PCWP at which a change in pattern occurred was 8.9 mmHg (8.3 to 9.6) for MSR to MSB, and 10.9 mmHg (10.1 to 11.8) for MSR to FC (p<0.001). There was no significant difference in mean values for all three observers. Movement of the Interatrial Septum predicts change in PCWP.
Sandy Clarke - One of the best experts on this subject based on the ideXlab platform.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Colin RoyseAbstract:BACKGROUND: Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS: In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS: Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION: Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Mohamed M Ali, Colin RoyseAbstract:BACKGROUND Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
David Canty - One of the best experts on this subject based on the ideXlab platform.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Colin RoyseAbstract:BACKGROUND: Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS: In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS: Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION: Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.
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Interatrial Septum motion but not doppler assessment predicts elevated pulmonary capillary wedge pressure in patients undergoing cardiac surgery
Anesthesiology, 2014Co-Authors: Darsim Haji, Alistair Royse, David Canty, Sandy Clarke, Mohamed M Ali, Colin RoyseAbstract:BACKGROUND Left atrial pressure and its surrogate, pulmonary capillary wedge pressure (PCWP), are important for determining diastolic function. The role of transthoracic echocardiography (TTE) in assessing diastolic function is well established in awake subjects. The objective was to assess the accuracy of predicting PCWP by TTE and transesophageal echocardiography (TEE) during coronary artery surgery. METHODS In 27 adult patients undergoing on-pump coronary artery surgery, simultaneous echocardiographic and hemodynamic measurements were obtained immediately before anesthesia (TTE), after anesthesia and mechanical ventilation (TTE and TEE), during conduit harvest (TEE), and after separation from cardiopulmonary bypass (TEE). RESULTS Twenty patients had an ejection fraction (EF) of 0.5 or greater. With the exception of E/e' and S/D ratios, echocardiographic values changed over the echocardiographic studies. In patients with low EF, E velocity, deceleration time, pulmonary vein D, S/D, and E/e' ratios correlated well with PCWP before anesthesia. After induction of anesthesia using TTE or TEE, correlations were poor. In normal EF patients, correlations were poor for both TEE and TTE at all five stages. The sensitivity and specificity of echocardiographic values were not high enough to predict raised PCWP except for a fixed curve pattern of Interatrial Septum (area under the curve 0.89 for PCWP ≥ 17, and 0.98 for ≥ 18 mmHg) and S/D less than 1 (area under the curve 0.74 for PCWP ≥ 17, and 0.78 for ≥ 18 mmHg). CONCLUSION Doppler assessment of PCWP was neither sensitive nor specific enough to be clinically useful in anesthetized patients with mechanical ventilation. The fixed curve pattern of the Interatrial Septum was the best predictor of raised PCWP.