The Experts below are selected from a list of 162 Experts worldwide ranked by ideXlab platform
Ferenc Hajos - One of the best experts on this subject based on the ideXlab platform.
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sexual dimorphism of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Acta Biologica Hungarica, 2001Co-Authors: Balazs Gerics, Ferenc Hajos, Katalin Halasy, Ferenc SzalayAbstract:The intensity of immunostaining for the glial fibrillary acidic protein (GFAP) is outstandingly high in the Interpeduncular Nucleus. This Nucleus was compared in males and females for its GFAP immunoreaction. Immunohistochemistry was carried out on free floating vibratome slices and evaluated by surface den- sitometry. While in males the reactions were similar, females showed individual variations. Since the interpe- duncular Nucleus is a hormonally inactive brain area where gonadal hormones do not induce plastic synaptic changes, it is concluded that concerning this astroglial marker a sexual dimorphism exists also outside the ihendocrine brainli.
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ovarian cycle related changes of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Brain Research, 2000Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc Szalay, Eleni Michaloudi, Georgios C PapadopoulosAbstract:Abstract The Interpeduncular Nucleus (IPN) of female rats was studied across the estrous cycle to observe whether the expression of the astroglial marker, glial fibrillary acidic protein (GFAP) reacts to hormonal changes in an area not belonging to the ‘endocrine brain’. A marked reduction of immunoreactive GFAP was observed in estrus as compared to the immunoreactivities in met- and proestrus. This finding is consistent with earlier observations in the endocrine hypothalamus, but also proves that gonadal steroids influence astroglia in brain regions not involved in neuroendocrine regulation. Since cyclic fluctuations of synaptic numbers in the female have been described only for the endocrine hypothalamus, decrease of immunoreactive GFAP in the IPN during estrus may reflect a down-regulation of GFAP synthesis.
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glial fibrillary acidic protein gfap immunoreactivity is reduced by castration in the Interpeduncular Nucleus of male rats
Neuroreport, 1999Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc SzalayAbstract:THE Interpeduncular Nucleus of adult male rats was investigated for glial fibrillary acidic protein immunoreactivity. In intact animals the Nucleus had an outstandingly intense immunostaining, particularly at its periphery, including the rostral, lateral, dorsomedial and dorsolateral subnuclei where, in addition to neuropil astrocytes, a substantial amount of perivascular glia was found. Four weeks after castration, immunostaining decreased markedly in the core region of the Nucleus corresponding to the caudal and medial subnuclei, and to a much lesser extent at the periphery. The immunoreactivity in pericapillary astrocytes proved to be insensitive to castration. Testosterone, if administered after castration prevented or restituted the loss of immunoreactivity. Beyond 4 months after castration, the effect of testosterone gradually declined. It is concluded that testosterone stimulates the expression of glial fibrillary acidic protein immunoreactivity in the Interpeduncular Nucleus. Our findings support the argument that gonadal steroids can influence astrocytes also in non-endocrine areas of the brain.
Ferenc Szalay - One of the best experts on this subject based on the ideXlab platform.
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sexual dimorphism of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Acta Biologica Hungarica, 2001Co-Authors: Balazs Gerics, Ferenc Hajos, Katalin Halasy, Ferenc SzalayAbstract:The intensity of immunostaining for the glial fibrillary acidic protein (GFAP) is outstandingly high in the Interpeduncular Nucleus. This Nucleus was compared in males and females for its GFAP immunoreaction. Immunohistochemistry was carried out on free floating vibratome slices and evaluated by surface den- sitometry. While in males the reactions were similar, females showed individual variations. Since the interpe- duncular Nucleus is a hormonally inactive brain area where gonadal hormones do not induce plastic synaptic changes, it is concluded that concerning this astroglial marker a sexual dimorphism exists also outside the ihendocrine brainli.
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ovarian cycle related changes of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Brain Research, 2000Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc Szalay, Eleni Michaloudi, Georgios C PapadopoulosAbstract:Abstract The Interpeduncular Nucleus (IPN) of female rats was studied across the estrous cycle to observe whether the expression of the astroglial marker, glial fibrillary acidic protein (GFAP) reacts to hormonal changes in an area not belonging to the ‘endocrine brain’. A marked reduction of immunoreactive GFAP was observed in estrus as compared to the immunoreactivities in met- and proestrus. This finding is consistent with earlier observations in the endocrine hypothalamus, but also proves that gonadal steroids influence astroglia in brain regions not involved in neuroendocrine regulation. Since cyclic fluctuations of synaptic numbers in the female have been described only for the endocrine hypothalamus, decrease of immunoreactive GFAP in the IPN during estrus may reflect a down-regulation of GFAP synthesis.
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glial fibrillary acidic protein gfap immunoreactivity is reduced by castration in the Interpeduncular Nucleus of male rats
Neuroreport, 1999Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc SzalayAbstract:THE Interpeduncular Nucleus of adult male rats was investigated for glial fibrillary acidic protein immunoreactivity. In intact animals the Nucleus had an outstandingly intense immunostaining, particularly at its periphery, including the rostral, lateral, dorsomedial and dorsolateral subnuclei where, in addition to neuropil astrocytes, a substantial amount of perivascular glia was found. Four weeks after castration, immunostaining decreased markedly in the core region of the Nucleus corresponding to the caudal and medial subnuclei, and to a much lesser extent at the periphery. The immunoreactivity in pericapillary astrocytes proved to be insensitive to castration. Testosterone, if administered after castration prevented or restituted the loss of immunoreactivity. Beyond 4 months after castration, the effect of testosterone gradually declined. It is concluded that testosterone stimulates the expression of glial fibrillary acidic protein immunoreactivity in the Interpeduncular Nucleus. Our findings support the argument that gonadal steroids can influence astrocytes also in non-endocrine areas of the brain.
Georgios C Papadopoulos - One of the best experts on this subject based on the ideXlab platform.
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ovarian cycle related changes of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Brain Research, 2000Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc Szalay, Eleni Michaloudi, Georgios C PapadopoulosAbstract:Abstract The Interpeduncular Nucleus (IPN) of female rats was studied across the estrous cycle to observe whether the expression of the astroglial marker, glial fibrillary acidic protein (GFAP) reacts to hormonal changes in an area not belonging to the ‘endocrine brain’. A marked reduction of immunoreactive GFAP was observed in estrus as compared to the immunoreactivities in met- and proestrus. This finding is consistent with earlier observations in the endocrine hypothalamus, but also proves that gonadal steroids influence astroglia in brain regions not involved in neuroendocrine regulation. Since cyclic fluctuations of synaptic numbers in the female have been described only for the endocrine hypothalamus, decrease of immunoreactive GFAP in the IPN during estrus may reflect a down-regulation of GFAP synthesis.
Balazs Gerics - One of the best experts on this subject based on the ideXlab platform.
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sexual dimorphism of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Acta Biologica Hungarica, 2001Co-Authors: Balazs Gerics, Ferenc Hajos, Katalin Halasy, Ferenc SzalayAbstract:The intensity of immunostaining for the glial fibrillary acidic protein (GFAP) is outstandingly high in the Interpeduncular Nucleus. This Nucleus was compared in males and females for its GFAP immunoreaction. Immunohistochemistry was carried out on free floating vibratome slices and evaluated by surface den- sitometry. While in males the reactions were similar, females showed individual variations. Since the interpe- duncular Nucleus is a hormonally inactive brain area where gonadal hormones do not induce plastic synaptic changes, it is concluded that concerning this astroglial marker a sexual dimorphism exists also outside the ihendocrine brainli.
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ovarian cycle related changes of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Brain Research, 2000Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc Szalay, Eleni Michaloudi, Georgios C PapadopoulosAbstract:Abstract The Interpeduncular Nucleus (IPN) of female rats was studied across the estrous cycle to observe whether the expression of the astroglial marker, glial fibrillary acidic protein (GFAP) reacts to hormonal changes in an area not belonging to the ‘endocrine brain’. A marked reduction of immunoreactive GFAP was observed in estrus as compared to the immunoreactivities in met- and proestrus. This finding is consistent with earlier observations in the endocrine hypothalamus, but also proves that gonadal steroids influence astroglia in brain regions not involved in neuroendocrine regulation. Since cyclic fluctuations of synaptic numbers in the female have been described only for the endocrine hypothalamus, decrease of immunoreactive GFAP in the IPN during estrus may reflect a down-regulation of GFAP synthesis.
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glial fibrillary acidic protein gfap immunoreactivity is reduced by castration in the Interpeduncular Nucleus of male rats
Neuroreport, 1999Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc SzalayAbstract:THE Interpeduncular Nucleus of adult male rats was investigated for glial fibrillary acidic protein immunoreactivity. In intact animals the Nucleus had an outstandingly intense immunostaining, particularly at its periphery, including the rostral, lateral, dorsomedial and dorsolateral subnuclei where, in addition to neuropil astrocytes, a substantial amount of perivascular glia was found. Four weeks after castration, immunostaining decreased markedly in the core region of the Nucleus corresponding to the caudal and medial subnuclei, and to a much lesser extent at the periphery. The immunoreactivity in pericapillary astrocytes proved to be insensitive to castration. Testosterone, if administered after castration prevented or restituted the loss of immunoreactivity. Beyond 4 months after castration, the effect of testosterone gradually declined. It is concluded that testosterone stimulates the expression of glial fibrillary acidic protein immunoreactivity in the Interpeduncular Nucleus. Our findings support the argument that gonadal steroids can influence astrocytes also in non-endocrine areas of the brain.
Katalin Halasy - One of the best experts on this subject based on the ideXlab platform.
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sexual dimorphism of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Acta Biologica Hungarica, 2001Co-Authors: Balazs Gerics, Ferenc Hajos, Katalin Halasy, Ferenc SzalayAbstract:The intensity of immunostaining for the glial fibrillary acidic protein (GFAP) is outstandingly high in the Interpeduncular Nucleus. This Nucleus was compared in males and females for its GFAP immunoreaction. Immunohistochemistry was carried out on free floating vibratome slices and evaluated by surface den- sitometry. While in males the reactions were similar, females showed individual variations. Since the interpe- duncular Nucleus is a hormonally inactive brain area where gonadal hormones do not induce plastic synaptic changes, it is concluded that concerning this astroglial marker a sexual dimorphism exists also outside the ihendocrine brainli.
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ovarian cycle related changes of glial fibrillary acidic protein gfap immunoreactivity in the rat Interpeduncular Nucleus
Brain Research, 2000Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc Szalay, Eleni Michaloudi, Georgios C PapadopoulosAbstract:Abstract The Interpeduncular Nucleus (IPN) of female rats was studied across the estrous cycle to observe whether the expression of the astroglial marker, glial fibrillary acidic protein (GFAP) reacts to hormonal changes in an area not belonging to the ‘endocrine brain’. A marked reduction of immunoreactive GFAP was observed in estrus as compared to the immunoreactivities in met- and proestrus. This finding is consistent with earlier observations in the endocrine hypothalamus, but also proves that gonadal steroids influence astroglia in brain regions not involved in neuroendocrine regulation. Since cyclic fluctuations of synaptic numbers in the female have been described only for the endocrine hypothalamus, decrease of immunoreactive GFAP in the IPN during estrus may reflect a down-regulation of GFAP synthesis.
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glial fibrillary acidic protein gfap immunoreactivity is reduced by castration in the Interpeduncular Nucleus of male rats
Neuroreport, 1999Co-Authors: Ferenc Hajos, Katalin Halasy, Balazs Gerics, Ferenc SzalayAbstract:THE Interpeduncular Nucleus of adult male rats was investigated for glial fibrillary acidic protein immunoreactivity. In intact animals the Nucleus had an outstandingly intense immunostaining, particularly at its periphery, including the rostral, lateral, dorsomedial and dorsolateral subnuclei where, in addition to neuropil astrocytes, a substantial amount of perivascular glia was found. Four weeks after castration, immunostaining decreased markedly in the core region of the Nucleus corresponding to the caudal and medial subnuclei, and to a much lesser extent at the periphery. The immunoreactivity in pericapillary astrocytes proved to be insensitive to castration. Testosterone, if administered after castration prevented or restituted the loss of immunoreactivity. Beyond 4 months after castration, the effect of testosterone gradually declined. It is concluded that testosterone stimulates the expression of glial fibrillary acidic protein immunoreactivity in the Interpeduncular Nucleus. Our findings support the argument that gonadal steroids can influence astrocytes also in non-endocrine areas of the brain.
