The Experts below are selected from a list of 285 Experts worldwide ranked by ideXlab platform

A K Banerji - One of the best experts on this subject based on the ideXlab platform.

Rama Jayasundar - One of the best experts on this subject based on the ideXlab platform.

P Raghunathan - One of the best experts on this subject based on the ideXlab platform.

Myeong Cherl Kook - One of the best experts on this subject based on the ideXlab platform.

  • Intracranial Tuberculoma comparison of mr with pathologic findings
    American Journal of Neuroradiology, 1995
    Co-Authors: Kee Hyun Chang, Myeong Cherl Kook
    Abstract:

    PURPOSE: To compare the MR signal intensity patterns and enhancement pattern of Intracranial Tuberculomas with their histopathologic features. METHODS: MR images of six patients with surgically proved Intracranial Tuberculoma were reviewed retrospectively and were compared with histologic findings of the resected specimen. Detailed histologic examination was performed to look for the extent and characteristics of caseation necrosis, fibrosis, and inflammatory cellular infiltrates at each area of different signal intensities and at the enhancing areas on MR. Signal intensities for T1- and T2-weighted images were compared with normal gray matter. RESULTS: On T1-weighted images, the granulomas showed a slightly hyperintense rim surrounded by a complete or partial rim of slight hypointensity and central isointensity or mixed isointensity and hyperintensity in five patients and homogeneous isointensity in one patient. Histologically, the zone of central isointensity or mixed intensity corresponded to caseation necrosis plus adjacent cellular infiltrates. The hyperintense and hypointense rims corresponded to the layers of collagenous fiber and the layers of the inflammatory cellular infiltrates, respectively. On T2-weighted images, the entire portion of the granuloma showed slightly heterogeneous isointensity or hypointensity with small markedly hypointense foci in five patients, and a hyperintense center surrounded by a hypointense rim in one patient. Histologic layers were not discriminated on T2-weighted images. On postcontrast T1-weighted images, there were single or multiple conglomerate ring enhancements within a Tuberculoma in all six patients, corresponding to the layers of both collagenous and inflammatory cells. CONCLUSION: Combination of the described signal intensity patterns and conglomerate ringlike enhancing appearance of the lesion is characteristic of Tuberculoma, and may play an important role in differentiating Intracranial Tuberculomas from other ring-enhancing brain lesions.

Hosam A. Yousef - One of the best experts on this subject based on the ideXlab platform.

  • Intracranial Tuberculoma and recent advances in magnetic resonance imaging
    Egyptian Journal of Neurosurgery, 2018
    Co-Authors: Ahmad A. Moussa, Mohamed Mahmoud, Hosam A. Yousef
    Abstract:

    Tuberculosis is resurging both in the developing and developed worlds. This includes TB of the central nervous system which is more common in children. It carries a high mortality rate and can lead to significant levels of neurological morbidity. Magnetic resonance imaging offers the potential to diagnose Intracranial Tuberculoma and to differentiate it from other single hyper dense Intracranial lesions. The authors report thirteen patients who proved to have Intracranial Tuberculoma with emphasis on their magnetic resonance imaging. They all presented with varying degrees of raised Intracranial pressure. All the thirteen patients had a CT scan which showed a single hyper dense lesion. After contrast the density of the lesions increased. To confirm the diagnosis of Intracranial Tuberculomas and to differentiate it from Intracranial single hyper dense lesions, conventional pre and post contrast MRI imagining followed by FLAIR sequences and diffusion-weighted echo-planner imagining (EPI) was carried out. All our patients were treated by corticosteroids for eight weeks and anti-tuberculous medication for a minimum period of twelve months. The treatment was successful in all our patients and none required surgery. Early and clear diagnosis of Intracranial Tuberculoma can be achieved by MRI imaging including flair sequences and diffusion-weighted Echo-planner imaging, (EPI). This leads to early treatment and better outcomes of tuberculosis of the central nervous system. This study was not registered as a trial because it is a retrospective study that does not include any involvement in the management or follow-up of patients and as such did not require registering.

  • Intracranial Tuberculoma and recent advances in magnetic resonance imaging
    Egyptian Journal of Neurosurgery, 2018
    Co-Authors: Ahmad A. Moussa, Mohamed E. Mahmoud, Hosam A. Yousef
    Abstract:

    Background Tuberculosis is resurging both in the developing and developed worlds. This includes TB of the central nervous system which is more common in children. It carries a high mortality rate and can lead to significant levels of neurological morbidity. Magnetic resonance imaging offers the potential to diagnose Intracranial Tuberculoma and to differentiate it from other single hyper dense Intracranial lesions. Methods The authors report thirteen patients who proved to have Intracranial Tuberculoma with emphasis on their magnetic resonance imaging. They all presented with varying degrees of raised Intracranial pressure. All the thirteen patients had a CT scan which showed a single hyper dense lesion. After contrast the density of the lesions increased. To confirm the diagnosis of Intracranial Tuberculomas and to differentiate it from Intracranial single hyper dense lesions, conventional pre and post contrast MRI imagining followed by FLAIR sequences and diffusion-weighted echo-planner imagining (EPI) was carried out. Results All our patients were treated by corticosteroids for eight weeks and anti-tuberculous medication for a minimum period of twelve months. The treatment was successful in all our patients and none required surgery. Conclusions Early and clear diagnosis of Intracranial Tuberculoma can be achieved by MRI imaging including flair sequences and diffusion-weighted Echo-planner imaging, (EPI). This leads to early treatment and better outcomes of tuberculosis of the central nervous system. Trial registration This study was not registered as a trial because it is a retrospective study that does not include any involvement in the management or follow-up of patients and as such did not require registering.