The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform
Xing Xiangzhon - One of the best experts on this subject based on the ideXlab platform.
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A comparative study about efficiency of StJohn's wort extract in the treatment of female patients with Involutional Depression
Journal of psychiatry, 2011Co-Authors: Xing XiangzhonAbstract:Objective To investigate the efficiency and safety of St.John's wort extract in the treatment of female patients with Involutional Depression.Methods A total of 64 female patients with Involutional Depression were randomly divided into study group treated with St.John's wort extract and control group treated with paroxetine for 6 weeks.Efficiency and safety were assessed with Clinical Global Impressions(CGI),the 24-item Hamilton Depression Rating Scale(HAMD-24),Hamilton Anxiety Rating Scale(HAMA),Treatment Emergent Symptom Scale(TESS) at the baseline,the 2nd weekend,4th weekend and 6th weekend after treatment.Results There was no significant difference in the effective rate between study group and control group(81.25% vs.84.38%,P0.05).Compared with the baseline,total scores of HAMD and HAMA in the two groups decreased significantly from the 2nd weekend(P0.01).There were no significant differences in total scores of HAMD and HAMA between the two groups at each interview-point(P0.05).Side effects were few in both of the groups,but the score of TESS in study group was significantly lower than that in control group(P0.05).Conclusion St.John wort extract is effective for the treatment of Involutional depressive with less side effects and high safety.
Wang Xiaoyun - One of the best experts on this subject based on the ideXlab platform.
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Relationship Between the Occurrence of Involutional Depression andSerum Estrogen Level in Menopausal Women
Journal of Guangzhou University of Traditional Chinese Medicine, 2001Co-Authors: Wang XiaoyunAbstract:Objective To detect the serum estrogen level in women with involution al Depression (ID) and to study the effect of estrogen on the occurrence of ID. Methods Serum estrogen levels at 7:00 am were detec ted by r adioimmunoassay in 40 normal menopausal women (Group A) and 49 cases of ID (Grou p B), and compared with those of 36 cases previously detected. Results Estro gen level was much lower in Group B than Group A (P 0.01 ) but similar to Group C (P 0.05 ). Co nclusion The occurrence of ID in menopausal women may be related to t he decrease of estrogen level, but the specific correlation of the above two has not been proved yet.
