The Experts below are selected from a list of 18147 Experts worldwide ranked by ideXlab platform
Xinsong Li - One of the best experts on this subject based on the ideXlab platform.
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in vitro and in vivo evaluatIon of ketotifen fumarate loaded silicone hydrogel contact lenses for ocular drug delivery
Drug Delivery, 2011Co-Authors: Jinku Xu, Xinsong LiAbstract:The purpose of this work was to evaluate the usefulness of silicone hydrogel contact lenses loaded with ketotifen fumarate for ocular drug delivery. First, silicone contact lenses were prepared by photopolymerizatIon of bitelechelic methacrylated polydimethylsiloxanes macromonomer, 3-methacryloxypropyltris(trimethylsiloxy)silane, and N,N-dimethylacrylamide using ethylene glycol dimethacrylate as a cross-linker and Darocur 1173 as an initiator followed by surface plasma treatment. Then, the silicone hydrogel matrices of the contact lenses were characterized by equilibrium swelling ratio (ESR), tensile tests, Ion Permeability, and surface contact angle. Finally, the contact lenses were loaded with ketotifen fumarate by pre-soaking in drug solutIon to evaluate drug loading capacity, in vitro and in vivo release behavior of the silicone contact lenses. The results showed that ESR and Ion Permeability increase, and the surface contact angle and tensile strength decreased with the increase of DMA component in t...
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in vitro and in vivo evaluatIon of ketotifen fumarate loaded silicone hydrogel contact lenses for ocular drug delivery
Drug Delivery, 2011Co-Authors: Jinku Xu, Xinsong LiAbstract:The purpose of this work was to evaluate the usefulness of silicone hydrogel contact lenses loaded with ketotifen fumarate for ocular drug delivery. First, silicone contact lenses were prepared by photopolymerizatIon of bitelechelic methacrylated polydimethylsiloxanes macromonomer, 3-methacryloxypropyltris(trimethylsiloxy)silane, and N,N-dimethylacrylamide using ethylene glycol dimethacrylate as a cross-linker and Darocur 1173 as an initiator followed by surface plasma treatment. Then, the silicone hydrogel matrices of the contact lenses were characterized by equilibrium swelling ratio (ESR), tensile tests, Ion Permeability, and surface contact angle. Finally, the contact lenses were loaded with ketotifen fumarate by pre-soaking in drug solutIon to evaluate drug loading capacity, in vitro and in vivo release behavior of the silicone contact lenses. The results showed that ESR and Ion Permeability increase, and the surface contact angle and tensile strength decreased with the increase of DMA component in t...
Jinku Xu - One of the best experts on this subject based on the ideXlab platform.
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in vitro and in vivo evaluatIon of ketotifen fumarate loaded silicone hydrogel contact lenses for ocular drug delivery
Drug Delivery, 2011Co-Authors: Jinku Xu, Xinsong LiAbstract:The purpose of this work was to evaluate the usefulness of silicone hydrogel contact lenses loaded with ketotifen fumarate for ocular drug delivery. First, silicone contact lenses were prepared by photopolymerizatIon of bitelechelic methacrylated polydimethylsiloxanes macromonomer, 3-methacryloxypropyltris(trimethylsiloxy)silane, and N,N-dimethylacrylamide using ethylene glycol dimethacrylate as a cross-linker and Darocur 1173 as an initiator followed by surface plasma treatment. Then, the silicone hydrogel matrices of the contact lenses were characterized by equilibrium swelling ratio (ESR), tensile tests, Ion Permeability, and surface contact angle. Finally, the contact lenses were loaded with ketotifen fumarate by pre-soaking in drug solutIon to evaluate drug loading capacity, in vitro and in vivo release behavior of the silicone contact lenses. The results showed that ESR and Ion Permeability increase, and the surface contact angle and tensile strength decreased with the increase of DMA component in t...
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in vitro and in vivo evaluatIon of ketotifen fumarate loaded silicone hydrogel contact lenses for ocular drug delivery
Drug Delivery, 2011Co-Authors: Jinku Xu, Xinsong LiAbstract:The purpose of this work was to evaluate the usefulness of silicone hydrogel contact lenses loaded with ketotifen fumarate for ocular drug delivery. First, silicone contact lenses were prepared by photopolymerizatIon of bitelechelic methacrylated polydimethylsiloxanes macromonomer, 3-methacryloxypropyltris(trimethylsiloxy)silane, and N,N-dimethylacrylamide using ethylene glycol dimethacrylate as a cross-linker and Darocur 1173 as an initiator followed by surface plasma treatment. Then, the silicone hydrogel matrices of the contact lenses were characterized by equilibrium swelling ratio (ESR), tensile tests, Ion Permeability, and surface contact angle. Finally, the contact lenses were loaded with ketotifen fumarate by pre-soaking in drug solutIon to evaluate drug loading capacity, in vitro and in vivo release behavior of the silicone contact lenses. The results showed that ESR and Ion Permeability increase, and the surface contact angle and tensile strength decreased with the increase of DMA component in t...
Liquan Chen - One of the best experts on this subject based on the ideXlab platform.
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properties investigatIon of sulfonated poly ether ether ketone polyacrylonitrile acid base blend membrane for vanadium redox flow battery applicatIon
ACS Applied Materials & Interfaces, 2014Co-Authors: Wenjing Dai, Xinping Qiu, Le Liu, Liquan ChenAbstract:Acid–base blend membrane prepared from sulfonated poly(ether ether ketone) (SPEEK) and polyacrylonitrile (PAN) was detailedly evaluated for vanadium redox flow battery (VRFB) applicatIon. SPEEK/PAN blend membrane exhibited dense and homogeneous cross-sectIon morphology as scanning electron microscopy and energy-dispersive X-ray spectroscopy images show. The acid–base interactIon of Ionic cross-linking and hydrogen bonding between SPEEK and PAN could effectively reduce water uptake, swelling ratio, and vanadium Ion Permeability, and improve the performance and stability of blend membrane. Because of the good balance of proton conductivity and vanadium Ion Permeability, blend membrane with 20 wt % PAN (S/PAN-20%) showed higher Coulombic efficiency (96.2% vs 91.1%) and energy efficiency (83.5% vs 78.4%) than NafIon 117 membrane at current density of 80 mA cm–2 when they were used in VRFB single cell. Besides, S/PAN-20% membrane kept a stable performance during 150 cycles at current density of 80 mA cm–2 in t...
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self assembled polyelectrolyte multilayer modified nafIon membrane with suppressed vanadium Ion crossover for vanadium redox flow batteries
Journal of Materials Chemistry, 2008Co-Authors: Jingyu Xi, Xiangguo Teng, Yongtao Zhao, Zenghua Wu, Liquan ChenAbstract:The crossover of vanadium Ions through proton-exchange membranes such as those of NafIon is the chief reason that results in the low energy efficiency and high self-discharge rate of vanadium redox flow batteries (VRB). With respect to applicability, the ideal proton-exchange membrane used in VRB should possess simultaneously high proton conductivity and low vanadium Ion Permeability. Here, we report a novel approach using a polyelectrolyte layer-by-layer self-assembly technique to fabricate a barrier layer onto the surface of NafIon membrane by alternate adsorptIon of polycatIon poly(diallyldimethylammonium chloride) (PDDA) and polyanIon poly(sodium styrene sulfonate) (PSS), which can suppress the crossover of vanadium Ions. The NafIon–[PDDA-PSS]n membrane (n = the number of multilayers) obtained shows much lower vanadium Ion Permeability compared with plain NafIon membrane. Accordingly, the VRB with NafIon–[PDDA-PSS]n membrane exhibits a higher coulombic efficiency (CE) and energy efficiency (EE) together with a slower self-discharge rate than that of NafIon system. The highest CE of 97.6% and EE of 83.9% can be achieved at charge–discharge current density of 80 mA cm−2 and 20 mA cm−2, respectively.
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self assembled polyelectrolyte multilayer modified nafIon membrane with suppressed vanadium Ion crossover for vanadium redox flow batteries
Journal of Materials Chemistry, 2008Co-Authors: Xiangguo Teng, Yongtao Zhao, Liquan Chen, Xinping QiuAbstract:The crossover of vanadium Ions through proton-exchange membranes such as those of NafIon is the chief reason that results in the low energy efficiency and high self-discharge rate of vanadium redox flow batteries (VRB). With respect to applicability, the ideal proton-exchange membrane used in VRB should possess simultaneously high proton conductivity and low vanadium Ion Permeability. Here, we report a novel approach using a polyelectrolyte layer-by-layer self-assembly technique to fabricate a barrier layer onto the surface of NafIon membrane by alternate adsorptIon of polycatIon poly(diallyldimethylammonium chloride) (PDDA) and polyanIon poly(sodium styrene sulfonate) (PSS), which can suppress the crossover of vanadium Ions. The NafIon–[PDDA-PSS]n membrane (n = the number of multilayers) obtained shows much lower vanadium Ion Permeability compared with plain NafIon membrane. Accordingly, the VRB with NafIon–[PDDA-PSS]n membrane exhibits a higher coulombic efficiency (CE) and energy efficiency (EE) together with a slower self-discharge rate than that of NafIon system. The highest CE of 97.6% and EE of 83.9% can be achieved at charge–discharge current density of 80 mA cm−2 and 20 mA cm−2, respectively.
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influences of permeatIon of vanadium Ions through pvdf g pssa membranes on performances of vanadium redox flow batteries
Journal of Physical Chemistry B, 2005Co-Authors: Xuanli Luo, Liquan Chen, Jingyu Xi, Zenghua Wu, Zhengzhong Lu, Wentao Zhu, Xinping QiuAbstract:The preparatIon and physical characterizatIon of a poly(vinylidene fluoride)-graft-poly(styrene sulfonic acid) (PVDF-g-PSSA) membrane prepared by a solutIon-grafting method were described. These membranes exhibited high conductivity with a value 3.22 × 10-2 S/cm at 30 °C. ICP studies revealed that the PVDF-g-PSSA membrane showed dramatically lower vanadium Ion Permeability compared to NafIon 117. Trivalent vanadium Ions had the highest Permeability through all these membranes in contrast to pentavalent vanadium Ions with the lowest. The VRB with the low-cost PVDF-g-PSSA membrane exhibited a higher performance than that with NafIon 117 under the same operating conditIons, and its energy efficiency reached 75.8% at 30 mA/cm2. The performance of VRB with the PVDF-g-PSSA membrane can be maintained after more than 200 cycles at a current density of 60 mA/cm2.
Hua Dai - One of the best experts on this subject based on the ideXlab platform.
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sulfonated poly tetramethydiphenyl ether ether ketone membranes for vanadium redox flow battery applicatIon
Journal of Power Sources, 2011Co-Authors: Huamin Zhang, Zhensheng Mai, Hua DaiAbstract:Abstract Sulfonated poly(tetramethydiphenyl ether ether ketone) (SPEEK) with various degree of sulfonatIon is prepared and first used as Ion exchange membrane for vanadium redox flow battery (VRB) applicatIon. The vanadium Ion Permeability of SPEEK40 membrane is one order of magnitude lower than that of NafIon 115 membrane. The low cost SPEEK membranes exhibit a better performance than NafIon at the same operating conditIon. VRB single cells with SPEEK membranes show very high energy efficiency (>84%), comparable to that of the NafIon, but at much higher columbic efficiency (>97%). In the self-discharge test, the duratIon of the cell with the SPEEK membrane is two times longer than that with NafIon 115. The membrane keeps a stable performance after 80-cycles charge–discharge test.
Xinping Qiu - One of the best experts on this subject based on the ideXlab platform.
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properties investigatIon of sulfonated poly ether ether ketone polyacrylonitrile acid base blend membrane for vanadium redox flow battery applicatIon
ACS Applied Materials & Interfaces, 2014Co-Authors: Wenjing Dai, Xinping Qiu, Le Liu, Liquan ChenAbstract:Acid–base blend membrane prepared from sulfonated poly(ether ether ketone) (SPEEK) and polyacrylonitrile (PAN) was detailedly evaluated for vanadium redox flow battery (VRFB) applicatIon. SPEEK/PAN blend membrane exhibited dense and homogeneous cross-sectIon morphology as scanning electron microscopy and energy-dispersive X-ray spectroscopy images show. The acid–base interactIon of Ionic cross-linking and hydrogen bonding between SPEEK and PAN could effectively reduce water uptake, swelling ratio, and vanadium Ion Permeability, and improve the performance and stability of blend membrane. Because of the good balance of proton conductivity and vanadium Ion Permeability, blend membrane with 20 wt % PAN (S/PAN-20%) showed higher Coulombic efficiency (96.2% vs 91.1%) and energy efficiency (83.5% vs 78.4%) than NafIon 117 membrane at current density of 80 mA cm–2 when they were used in VRFB single cell. Besides, S/PAN-20% membrane kept a stable performance during 150 cycles at current density of 80 mA cm–2 in t...
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self assembled polyelectrolyte multilayer modified nafIon membrane with suppressed vanadium Ion crossover for vanadium redox flow batteries
Journal of Materials Chemistry, 2008Co-Authors: Xiangguo Teng, Yongtao Zhao, Liquan Chen, Xinping QiuAbstract:The crossover of vanadium Ions through proton-exchange membranes such as those of NafIon is the chief reason that results in the low energy efficiency and high self-discharge rate of vanadium redox flow batteries (VRB). With respect to applicability, the ideal proton-exchange membrane used in VRB should possess simultaneously high proton conductivity and low vanadium Ion Permeability. Here, we report a novel approach using a polyelectrolyte layer-by-layer self-assembly technique to fabricate a barrier layer onto the surface of NafIon membrane by alternate adsorptIon of polycatIon poly(diallyldimethylammonium chloride) (PDDA) and polyanIon poly(sodium styrene sulfonate) (PSS), which can suppress the crossover of vanadium Ions. The NafIon–[PDDA-PSS]n membrane (n = the number of multilayers) obtained shows much lower vanadium Ion Permeability compared with plain NafIon membrane. Accordingly, the VRB with NafIon–[PDDA-PSS]n membrane exhibits a higher coulombic efficiency (CE) and energy efficiency (EE) together with a slower self-discharge rate than that of NafIon system. The highest CE of 97.6% and EE of 83.9% can be achieved at charge–discharge current density of 80 mA cm−2 and 20 mA cm−2, respectively.
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influences of permeatIon of vanadium Ions through pvdf g pssa membranes on performances of vanadium redox flow batteries
Journal of Physical Chemistry B, 2005Co-Authors: Xuanli Luo, Liquan Chen, Jingyu Xi, Zenghua Wu, Zhengzhong Lu, Wentao Zhu, Xinping QiuAbstract:The preparatIon and physical characterizatIon of a poly(vinylidene fluoride)-graft-poly(styrene sulfonic acid) (PVDF-g-PSSA) membrane prepared by a solutIon-grafting method were described. These membranes exhibited high conductivity with a value 3.22 × 10-2 S/cm at 30 °C. ICP studies revealed that the PVDF-g-PSSA membrane showed dramatically lower vanadium Ion Permeability compared to NafIon 117. Trivalent vanadium Ions had the highest Permeability through all these membranes in contrast to pentavalent vanadium Ions with the lowest. The VRB with the low-cost PVDF-g-PSSA membrane exhibited a higher performance than that with NafIon 117 under the same operating conditIons, and its energy efficiency reached 75.8% at 30 mA/cm2. The performance of VRB with the PVDF-g-PSSA membrane can be maintained after more than 200 cycles at a current density of 60 mA/cm2.
