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Miltiadis Papathanassiou - One of the best experts on this subject based on the ideXlab platform.
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an atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy
Ocular Immunology and Inflammation, 2013Co-Authors: Lamprini Papaioannou, Georgios Tsolkas, Panagiotis Theodossiadis, Miltiadis PapathanassiouAbstract:AbstractPurpose: To present an atypical case of herpes simplex virus (HSV) endotheliitis.Methods: The authors report the case of a 62-year-old female patient who presented with unilateral diffuse corneal edema with Descemet's membrane folds and bullae, without keratic precipitates, Iritis, significant anterior chamber reaction, or intraocular pressure (IOP) elevation. The patient had no documented positive history of ocular surgery and no abnormal findings were present in the fellow eye. Endotheliitis of viral origin was suspected and Goldmann-Witmer coefficient for HSV, cytomegalovirus, and varicela zoster virus was calculated.Results: Goldmann-Witmer coefficient was positive for HSV. Treatment with oral valacyclovir and topical dexamethasone resulted in complete resolution of corneal edema within 1 week.Conclusions: HSV endotheliitis can present with bullous keratopathy as the only clinical manifestation, without typical findings such as keratic precipitates, Iritis, and IOP elevation.
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an atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy
Ocular Immunology and Inflammation, 2013Co-Authors: Lamprini Papaioannou, Georgios Tsolkas, Panagiotis Theodossiadis, Miltiadis PapathanassiouAbstract:AbstractPurpose: To present an atypical case of herpes simplex virus (HSV) endotheliitis.Methods: The authors report the case of a 62-year-old female patient who presented with unilateral diffuse corneal edema with Descemet's membrane folds and bullae, without keratic precipitates, Iritis, significant anterior chamber reaction, or intraocular pressure (IOP) elevation. The patient had no documented positive history of ocular surgery and no abnormal findings were present in the fellow eye. Endotheliitis of viral origin was suspected and Goldmann-Witmer coefficient for HSV, cytomegalovirus, and varicela zoster virus was calculated.Results: Goldmann-Witmer coefficient was positive for HSV. Treatment with oral valacyclovir and topical dexamethasone resulted in complete resolution of corneal edema within 1 week.Conclusions: HSV endotheliitis can present with bullous keratopathy as the only clinical manifestation, without typical findings such as keratic precipitates, Iritis, and IOP elevation.
Lamprini Papaioannou - One of the best experts on this subject based on the ideXlab platform.
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an atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy
Ocular Immunology and Inflammation, 2013Co-Authors: Lamprini Papaioannou, Georgios Tsolkas, Panagiotis Theodossiadis, Miltiadis PapathanassiouAbstract:AbstractPurpose: To present an atypical case of herpes simplex virus (HSV) endotheliitis.Methods: The authors report the case of a 62-year-old female patient who presented with unilateral diffuse corneal edema with Descemet's membrane folds and bullae, without keratic precipitates, Iritis, significant anterior chamber reaction, or intraocular pressure (IOP) elevation. The patient had no documented positive history of ocular surgery and no abnormal findings were present in the fellow eye. Endotheliitis of viral origin was suspected and Goldmann-Witmer coefficient for HSV, cytomegalovirus, and varicela zoster virus was calculated.Results: Goldmann-Witmer coefficient was positive for HSV. Treatment with oral valacyclovir and topical dexamethasone resulted in complete resolution of corneal edema within 1 week.Conclusions: HSV endotheliitis can present with bullous keratopathy as the only clinical manifestation, without typical findings such as keratic precipitates, Iritis, and IOP elevation.
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an atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy
Ocular Immunology and Inflammation, 2013Co-Authors: Lamprini Papaioannou, Georgios Tsolkas, Panagiotis Theodossiadis, Miltiadis PapathanassiouAbstract:AbstractPurpose: To present an atypical case of herpes simplex virus (HSV) endotheliitis.Methods: The authors report the case of a 62-year-old female patient who presented with unilateral diffuse corneal edema with Descemet's membrane folds and bullae, without keratic precipitates, Iritis, significant anterior chamber reaction, or intraocular pressure (IOP) elevation. The patient had no documented positive history of ocular surgery and no abnormal findings were present in the fellow eye. Endotheliitis of viral origin was suspected and Goldmann-Witmer coefficient for HSV, cytomegalovirus, and varicela zoster virus was calculated.Results: Goldmann-Witmer coefficient was positive for HSV. Treatment with oral valacyclovir and topical dexamethasone resulted in complete resolution of corneal edema within 1 week.Conclusions: HSV endotheliitis can present with bullous keratopathy as the only clinical manifestation, without typical findings such as keratic precipitates, Iritis, and IOP elevation.
Georgios Tsolkas - One of the best experts on this subject based on the ideXlab platform.
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an atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy
Ocular Immunology and Inflammation, 2013Co-Authors: Lamprini Papaioannou, Georgios Tsolkas, Panagiotis Theodossiadis, Miltiadis PapathanassiouAbstract:AbstractPurpose: To present an atypical case of herpes simplex virus (HSV) endotheliitis.Methods: The authors report the case of a 62-year-old female patient who presented with unilateral diffuse corneal edema with Descemet's membrane folds and bullae, without keratic precipitates, Iritis, significant anterior chamber reaction, or intraocular pressure (IOP) elevation. The patient had no documented positive history of ocular surgery and no abnormal findings were present in the fellow eye. Endotheliitis of viral origin was suspected and Goldmann-Witmer coefficient for HSV, cytomegalovirus, and varicela zoster virus was calculated.Results: Goldmann-Witmer coefficient was positive for HSV. Treatment with oral valacyclovir and topical dexamethasone resulted in complete resolution of corneal edema within 1 week.Conclusions: HSV endotheliitis can present with bullous keratopathy as the only clinical manifestation, without typical findings such as keratic precipitates, Iritis, and IOP elevation.
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an atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy
Ocular Immunology and Inflammation, 2013Co-Authors: Lamprini Papaioannou, Georgios Tsolkas, Panagiotis Theodossiadis, Miltiadis PapathanassiouAbstract:AbstractPurpose: To present an atypical case of herpes simplex virus (HSV) endotheliitis.Methods: The authors report the case of a 62-year-old female patient who presented with unilateral diffuse corneal edema with Descemet's membrane folds and bullae, without keratic precipitates, Iritis, significant anterior chamber reaction, or intraocular pressure (IOP) elevation. The patient had no documented positive history of ocular surgery and no abnormal findings were present in the fellow eye. Endotheliitis of viral origin was suspected and Goldmann-Witmer coefficient for HSV, cytomegalovirus, and varicela zoster virus was calculated.Results: Goldmann-Witmer coefficient was positive for HSV. Treatment with oral valacyclovir and topical dexamethasone resulted in complete resolution of corneal edema within 1 week.Conclusions: HSV endotheliitis can present with bullous keratopathy as the only clinical manifestation, without typical findings such as keratic precipitates, Iritis, and IOP elevation.
Panagiotis Theodossiadis - One of the best experts on this subject based on the ideXlab platform.
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an atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy
Ocular Immunology and Inflammation, 2013Co-Authors: Lamprini Papaioannou, Georgios Tsolkas, Panagiotis Theodossiadis, Miltiadis PapathanassiouAbstract:AbstractPurpose: To present an atypical case of herpes simplex virus (HSV) endotheliitis.Methods: The authors report the case of a 62-year-old female patient who presented with unilateral diffuse corneal edema with Descemet's membrane folds and bullae, without keratic precipitates, Iritis, significant anterior chamber reaction, or intraocular pressure (IOP) elevation. The patient had no documented positive history of ocular surgery and no abnormal findings were present in the fellow eye. Endotheliitis of viral origin was suspected and Goldmann-Witmer coefficient for HSV, cytomegalovirus, and varicela zoster virus was calculated.Results: Goldmann-Witmer coefficient was positive for HSV. Treatment with oral valacyclovir and topical dexamethasone resulted in complete resolution of corneal edema within 1 week.Conclusions: HSV endotheliitis can present with bullous keratopathy as the only clinical manifestation, without typical findings such as keratic precipitates, Iritis, and IOP elevation.
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an atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy
Ocular Immunology and Inflammation, 2013Co-Authors: Lamprini Papaioannou, Georgios Tsolkas, Panagiotis Theodossiadis, Miltiadis PapathanassiouAbstract:AbstractPurpose: To present an atypical case of herpes simplex virus (HSV) endotheliitis.Methods: The authors report the case of a 62-year-old female patient who presented with unilateral diffuse corneal edema with Descemet's membrane folds and bullae, without keratic precipitates, Iritis, significant anterior chamber reaction, or intraocular pressure (IOP) elevation. The patient had no documented positive history of ocular surgery and no abnormal findings were present in the fellow eye. Endotheliitis of viral origin was suspected and Goldmann-Witmer coefficient for HSV, cytomegalovirus, and varicela zoster virus was calculated.Results: Goldmann-Witmer coefficient was positive for HSV. Treatment with oral valacyclovir and topical dexamethasone resulted in complete resolution of corneal edema within 1 week.Conclusions: HSV endotheliitis can present with bullous keratopathy as the only clinical manifestation, without typical findings such as keratic precipitates, Iritis, and IOP elevation.
Robert P Burns - One of the best experts on this subject based on the ideXlab platform.
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acute Iritis associated with primary sjogren s syndrome and high titer anti ss a ro and anti ss b la antibodies treatment with combination immunosuppressive therapy
Arthritis & Rheumatism, 1992Co-Authors: Alan J Bridges, Robert P BurnsAbstract:Objective. We describe a patient with primary Sjogren's syndrome who developed severe, acute, anterior uveitis (Iritis), an uncommon complication in this setting. Methods. We present the case report of the clinical findings, course, treatment, and resolution of the acute uveitis. Titers of anti—SS-A/Ro and anti-SS-B/La antibodies were assessed (by immunodiffusion), as were fluorescent antinuclear antibodies (on HEp-2 cells) and cryoglobulins. Results. Initial treatment with topical steroids, oral prednisone (20 mg/day), and oral methotrexate was unsuccessful. The Iritis resolved after combined treatment with intravenous cyclophosphamide (1,500 mg/month), high-dose prednisone (60 mg/day), and cyclosporine (5 mg/kg/day). Conclusion. An uncommon, severe complication of primary Sjogren's syndrome is acute uveitis. Combination immunosuppressive therapy may be needed to control this condition.