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John K Marshall - One of the best experts on this subject based on the ideXlab platform.
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systematic review and meta analysis the incidence and prognosis of post infectious Irritable Bowel Syndrome
Alimentary Pharmacology & Therapeutics, 2007Co-Authors: Marroon Thabane, Dan Kottachchi, John K MarshallAbstract:Summary Background Individual studies suggest that post-infectious Irritable Bowel Syndrome is common, but symptoms gradually improve. Aim To review evidence for an association between intestinal infection and development of Irritable Bowel Syndrome, assess the prognosis of post-infectious Irritable Bowel Syndrome and explore factors that increase the risk. Methods MEDLINE (1966–2007) and EMBASE (1980–2007) databases were searched to identify the studies of post-infectious Irritable Bowel Syndrome epidemiology. Data were extracted by two independent reviewers. Pooled odds ratios (POR) and corresponding 95% CI for incidence of Irritable Bowel Syndrome were estimated among the exposed and unexposed groups. Results Eighteen of 26 studies identified were eligible for inclusion. Intestinal infection was associated with increased odds of developing Irritable Bowel Syndrome at study end (POR = 5.86; 95% CI: 3.60–9.54). In subgroup analysis, the odds of developing Irritable Bowel Syndrome was increased at 3 months (POR = 7.58; 95% CI: 4.27–13.45), 6 months (POR = 5.18; 95% CI: 3.24–8.26), 12 months (POR = 6.37; 95% CI: 2.63–15.40) and 24–36 months (POR = 3.85; 95% CI: 2.95–5.02). Among all studies (controlled and uncontrolled), the pooled incidence of Irritable Bowel Syndrome at study conclusion was 10% (95% CI: 9.4–85.6). Subjects with post-infectious Irritable Bowel Syndrome were younger and more anxious and depressed than those without post-infectious Irritable Bowel Syndrome. Conclusion The odds of developing Irritable Bowel Syndrome are increased sixfold after acute gastrointestinal infection. Young age, prolonged fever, anxiety and depression are risk factors for post-infectious Irritable Bowel Syndrome.
Marroon Thabane - One of the best experts on this subject based on the ideXlab platform.
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systematic review and meta analysis the incidence and prognosis of post infectious Irritable Bowel Syndrome
Alimentary Pharmacology & Therapeutics, 2007Co-Authors: Marroon Thabane, Dan Kottachchi, John K MarshallAbstract:Summary Background Individual studies suggest that post-infectious Irritable Bowel Syndrome is common, but symptoms gradually improve. Aim To review evidence for an association between intestinal infection and development of Irritable Bowel Syndrome, assess the prognosis of post-infectious Irritable Bowel Syndrome and explore factors that increase the risk. Methods MEDLINE (1966–2007) and EMBASE (1980–2007) databases were searched to identify the studies of post-infectious Irritable Bowel Syndrome epidemiology. Data were extracted by two independent reviewers. Pooled odds ratios (POR) and corresponding 95% CI for incidence of Irritable Bowel Syndrome were estimated among the exposed and unexposed groups. Results Eighteen of 26 studies identified were eligible for inclusion. Intestinal infection was associated with increased odds of developing Irritable Bowel Syndrome at study end (POR = 5.86; 95% CI: 3.60–9.54). In subgroup analysis, the odds of developing Irritable Bowel Syndrome was increased at 3 months (POR = 7.58; 95% CI: 4.27–13.45), 6 months (POR = 5.18; 95% CI: 3.24–8.26), 12 months (POR = 6.37; 95% CI: 2.63–15.40) and 24–36 months (POR = 3.85; 95% CI: 2.95–5.02). Among all studies (controlled and uncontrolled), the pooled incidence of Irritable Bowel Syndrome at study conclusion was 10% (95% CI: 9.4–85.6). Subjects with post-infectious Irritable Bowel Syndrome were younger and more anxious and depressed than those without post-infectious Irritable Bowel Syndrome. Conclusion The odds of developing Irritable Bowel Syndrome are increased sixfold after acute gastrointestinal infection. Young age, prolonged fever, anxiety and depression are risk factors for post-infectious Irritable Bowel Syndrome.
Dan Kottachchi - One of the best experts on this subject based on the ideXlab platform.
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systematic review and meta analysis the incidence and prognosis of post infectious Irritable Bowel Syndrome
Alimentary Pharmacology & Therapeutics, 2007Co-Authors: Marroon Thabane, Dan Kottachchi, John K MarshallAbstract:Summary Background Individual studies suggest that post-infectious Irritable Bowel Syndrome is common, but symptoms gradually improve. Aim To review evidence for an association between intestinal infection and development of Irritable Bowel Syndrome, assess the prognosis of post-infectious Irritable Bowel Syndrome and explore factors that increase the risk. Methods MEDLINE (1966–2007) and EMBASE (1980–2007) databases were searched to identify the studies of post-infectious Irritable Bowel Syndrome epidemiology. Data were extracted by two independent reviewers. Pooled odds ratios (POR) and corresponding 95% CI for incidence of Irritable Bowel Syndrome were estimated among the exposed and unexposed groups. Results Eighteen of 26 studies identified were eligible for inclusion. Intestinal infection was associated with increased odds of developing Irritable Bowel Syndrome at study end (POR = 5.86; 95% CI: 3.60–9.54). In subgroup analysis, the odds of developing Irritable Bowel Syndrome was increased at 3 months (POR = 7.58; 95% CI: 4.27–13.45), 6 months (POR = 5.18; 95% CI: 3.24–8.26), 12 months (POR = 6.37; 95% CI: 2.63–15.40) and 24–36 months (POR = 3.85; 95% CI: 2.95–5.02). Among all studies (controlled and uncontrolled), the pooled incidence of Irritable Bowel Syndrome at study conclusion was 10% (95% CI: 9.4–85.6). Subjects with post-infectious Irritable Bowel Syndrome were younger and more anxious and depressed than those without post-infectious Irritable Bowel Syndrome. Conclusion The odds of developing Irritable Bowel Syndrome are increased sixfold after acute gastrointestinal infection. Young age, prolonged fever, anxiety and depression are risk factors for post-infectious Irritable Bowel Syndrome.
V Barghout - One of the best experts on this subject based on the ideXlab platform.
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Irritable Bowel Syndrome in the united states prevalence symptom patterns and impact
Alimentary Pharmacology & Therapeutics, 2005Co-Authors: A P S Hungin, Lin Chang, G R Locke, E H Dennis, V BarghoutAbstract:Summary Background : The impact of Irritable Bowel Syndrome, a gastrointestinal motility disorder, is underestimated and poorly quantified, as clinicians may see only a minority of sufferers. Aim : To determine the prevalence, symptom patterns and impact of Irritable Bowel Syndrome in the US. Methods : This two-phase community survey used quota sampling and random-digit telephone dialling (screening interview) to identify individuals with medically diagnosed Irritable Bowel Syndrome or individuals not formally diagnosed, but fulfilling Irritable Bowel Syndrome diagnostic criteria (Manning, Rome I or II). Information on Irritable Bowel Syndrome symptoms, general health status, lifestyle and impact of symptoms on individuals’ lives was collected using in-depth follow-up interviews. Data were also collected for healthy controls identified in the screening interviews. Results : The total prevalence of Irritable Bowel Syndrome in 5009 screening interviews was 14.1% (medically diagnosed: 3.3%; undiagnosed, but meeting Irritable Bowel Syndrome criteria: 10.8%). Abdominal pain/discomfort was the most common symptom prompting consultation. Most sufferers (74% medically diagnosed; 63% undiagnosed) reported alternating constipation and diarrhoea. Previously diagnosed gastrointestinal disorders occurred more often in sufferers than non-sufferers. Irritable Bowel Syndrome sufferers had more days off work (6.4 vs. 3.0) and days in bed, and reduced activities to a greater extent than non-sufferers. Conclusions : Most (76.6%) Irritable Bowel Syndrome sufferers in the US are undiagnosed. Irritable Bowel Syndrome has a substantial impact on sufferers’ well-being and health, with considerable socioeconomic consequences.
D. L. Dumitrașcu - One of the best experts on this subject based on the ideXlab platform.
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Pathogenic Factors in Postinfectious Irritable Bowel Syndrome - An Update.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 2020Co-Authors: Teodora Iacob, Doina F Ţăţulescu, Cristina Cijevschi Prelipcean, D. L. DumitrașcuAbstract:After acute infectious gastroenteritis, up to thirty percent of patients present prolonged gastrointestinal symptoms and a part of those affected patients can have the diagnostic criteria for postinfectious Irritable Bowel Syndrome. The main diagnosis of a patient with postinfectious Irritable Bowel Syndrome was till this summer, clinically based on Roma III criteria. The Rome IV criteria brought some changes that involve also the post infectious Irritable Bowel Syndrome, recognizing further the postinfectious IBS as a specific entity according to the multidimensional clinical chronic mucosal inflammation triggered by enteric infection, may underlie persistent Bowel symptoms in patients who develop postinfectious Irritable Bowel Syndrome.
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Therapy of the postinfectious Irritable Bowel Syndrome: an update.
Clujul medical (1957), 2017Co-Authors: Teodora Iacob, Doina F. Țățulescu, D. L. DumitrașcuAbstract:After acute infectious gastroenteritis, up to thirty percent of patients present prolonged gastrointestinal symptoms and a part of those affected patients can have the diagnostic criteria for postinfectious Irritable Bowel Syndrome. Treatment is symptom directed rather than curative and includes agents prescribed for the treatment of Irritable Bowel Syndrome in general. Prophylaxis or early treatment of acute bacterial diarrhea may reduce the risk of postinfectious Irritable Bowel Syndrome development by reducing the occurrence, duration, and severity of the chronic inflammation and mucosal alterations (all these believed to play an important role in disease persistence). Probiotic treatment is effective in restoring the intestinal microbiota in patients with Irritable Bowel Syndrome and in animal models there are improvements of postinfectious Irritable Bowel Syndrome. Fecal microbiota transplantation seems to be one of the most effective methods of treating the postinfectious Irritable Bowel Syndrome (with recurrent episodes) caused by Clostridium difficile .
