The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Jianrong Gao - One of the best experts on this subject based on the ideXlab platform.
-
the synthesis of benzo f isoindole 1 3 dicarboxylates via an i2 induced 1 3 dipolar cycloaddition reaction
ChemInform, 2014Co-Authors: Huanming Huang, Huaqing Dong, Jianhong Jia, Liang Han, Jianrong GaoAbstract:For the first time, an iodine-induced 1,3-dipolar cycloaddition reaction between quinones and N-substituted amino esters is reported providing a novel strategy for the synthesis of Isoindoles.
-
the synthesis of benzo f isoindole 1 3 dicarboxylates via an i2 induced 1 3 dipolar cycloaddition reaction
Journal of Organic Chemistry, 2013Co-Authors: Huanming Huang, Huaqing Dong, Jianhong Jia, Liang Han, Jianrong GaoAbstract:An I2-induced 1,3-dipolar cycloaddition reaction has been developed for the synthesis of benzo[f]isoindole-1,3-dicarboxylates from quinones and N-substituted amino esters. The reaction proceeds in good to excellent yields in one step from 3 equiv of amino ester to react with the quinone structure. The utility of this transformation has been highlighted by its use for the construction of benzo[f]isoindole-1,3-dicarboxylates, which have been identified in natural products exhibiting important biological activities.
Sundarababu Baskaran - One of the best experts on this subject based on the ideXlab platform.
-
a domino aza piancatelli rearrangement intramolecular diels alder reaction stereoselective synthesis of octahydro 1h cyclopenta cd isoindole
Organic Letters, 2019Co-Authors: Shaik Gouse, Narra Rajashekar Reddy, Sundarababu BaskaranAbstract:For the first time, an efficient one-pot method for the construction of an angularly fused 5–6–5 aza-tricyclic framework has been developed in a highly stereoselective manner. This domino reaction is a novel combination of aza-Piancatelli rearrangement and intramolecular Diels–Alder reaction, which readily furnishes hexahydro-2a,5-epoxy-cyclopenta[cd]isoindole adducts, bearing six contiguous stereogenic centers in very good yields. The BBr3-mediated cleavage of the oxa-bridged adduct results in the formation of octahydro-1H-cyclopenta[cd]isoindole, an aza-tricyclic BCE core of a gracilamine alkaloid.
-
A Domino Aza-Piancatelli Rearrangement/Intramolecular Diels–Alder Reaction: Stereoselective Synthesis of Octahydro‑1H‑cyclopenta[cd]isoindole
2019Co-Authors: Shaik Gouse, Narra Rajashekar Reddy, Sundarababu BaskaranAbstract:For the first time, an efficient one-pot method for the construction of an angularly fused 5–6–5 aza-tricyclic framework has been developed in a highly stereoselective manner. This domino reaction is a novel combination of aza-Piancatelli rearrangement and intramolecular Diels–Alder reaction, which readily furnishes hexahydro-2a,5-epoxy-cyclopenta[cd]isoindole adducts, bearing six contiguous stereogenic centers in very good yields. The BBr3-mediated cleavage of the oxa-bridged adduct results in the formation of octahydro-1H-cyclopenta[cd]isoindole, an aza-tricyclic BCE core of a gracilamine alkaloid
Huanming Huang - One of the best experts on this subject based on the ideXlab platform.
-
the synthesis of benzo f isoindole 1 3 dicarboxylates via an i2 induced 1 3 dipolar cycloaddition reaction
ChemInform, 2014Co-Authors: Huanming Huang, Huaqing Dong, Jianhong Jia, Liang Han, Jianrong GaoAbstract:For the first time, an iodine-induced 1,3-dipolar cycloaddition reaction between quinones and N-substituted amino esters is reported providing a novel strategy for the synthesis of Isoindoles.
-
the synthesis of benzo f isoindole 1 3 dicarboxylates via an i2 induced 1 3 dipolar cycloaddition reaction
Journal of Organic Chemistry, 2013Co-Authors: Huanming Huang, Huaqing Dong, Jianhong Jia, Liang Han, Jianrong GaoAbstract:An I2-induced 1,3-dipolar cycloaddition reaction has been developed for the synthesis of benzo[f]isoindole-1,3-dicarboxylates from quinones and N-substituted amino esters. The reaction proceeds in good to excellent yields in one step from 3 equiv of amino ester to react with the quinone structure. The utility of this transformation has been highlighted by its use for the construction of benzo[f]isoindole-1,3-dicarboxylates, which have been identified in natural products exhibiting important biological activities.
Shaik Gouse - One of the best experts on this subject based on the ideXlab platform.
-
a domino aza piancatelli rearrangement intramolecular diels alder reaction stereoselective synthesis of octahydro 1h cyclopenta cd isoindole
Organic Letters, 2019Co-Authors: Shaik Gouse, Narra Rajashekar Reddy, Sundarababu BaskaranAbstract:For the first time, an efficient one-pot method for the construction of an angularly fused 5–6–5 aza-tricyclic framework has been developed in a highly stereoselective manner. This domino reaction is a novel combination of aza-Piancatelli rearrangement and intramolecular Diels–Alder reaction, which readily furnishes hexahydro-2a,5-epoxy-cyclopenta[cd]isoindole adducts, bearing six contiguous stereogenic centers in very good yields. The BBr3-mediated cleavage of the oxa-bridged adduct results in the formation of octahydro-1H-cyclopenta[cd]isoindole, an aza-tricyclic BCE core of a gracilamine alkaloid.
-
A Domino Aza-Piancatelli Rearrangement/Intramolecular Diels–Alder Reaction: Stereoselective Synthesis of Octahydro‑1H‑cyclopenta[cd]isoindole
2019Co-Authors: Shaik Gouse, Narra Rajashekar Reddy, Sundarababu BaskaranAbstract:For the first time, an efficient one-pot method for the construction of an angularly fused 5–6–5 aza-tricyclic framework has been developed in a highly stereoselective manner. This domino reaction is a novel combination of aza-Piancatelli rearrangement and intramolecular Diels–Alder reaction, which readily furnishes hexahydro-2a,5-epoxy-cyclopenta[cd]isoindole adducts, bearing six contiguous stereogenic centers in very good yields. The BBr3-mediated cleavage of the oxa-bridged adduct results in the formation of octahydro-1H-cyclopenta[cd]isoindole, an aza-tricyclic BCE core of a gracilamine alkaloid
Xiaoming Feng - One of the best experts on this subject based on the ideXlab platform.
-
a chiral cobalt ii complex catalyzed enantioselective aza piancatelli rearrangement diels alder cascade reaction
Chemical Science, 2020Co-Authors: Bin Shen, Shunxi Dong, Xiaohua Liu, Xiaoming FengAbstract:A chiral N,N′-dioxide/cobalt(II) complex catalyzed highly diastereoselective and enantioselective tandem aza-Piancatelli rearrangement/intramolecular Diels–Alder reaction has been disclosed. Various valuable hexahydro-2a,5-epoxycyclopenta[cd]Isoindoles bearing six contiguous stereocenters have been obtained in good yields with excellent diastereo- and enantio-selectivities from a wide range of both readily available 2-furylcarbinols and N-(furan-2-ylmethyl)anilines.
