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Jayakar V. Nayak - One of the best experts on this subject based on the ideXlab platform.

  • Defining surgical criteria for empty nose syndrome: Validation of the office-based cotton test and clinical interpretability of the validated Empty Nose Syndrome 6-Item Questionnaire.
    The Laryngoscope, 2017
    Co-Authors: Andrew Thamboo, Nathalia Velasquez, Al-rahim R. Habib, David Zarabanda, Hassan Paknezhad, Jayakar V. Nayak
    Abstract:

    Objectives/Hypothesis The validated Empty Nose Syndrome 6-Item Questionnaire (ENS6Q) identifies empty nose syndrome (ENS) patients. The unvalidated cotton test assesses improvement in ENS-related symptoms. By first validating the cotton test using the ENS6Q, we define the minimal clinically important difference (MCID) score for the ENS6Q. Study Design Individual case–control study. Methods Fifteen patients diagnosed with ENS and 18 controls with non-ENS sinonasal conditions underwent office cotton placement. Both groups completed ENS6Q testing in three conditions—precotton, cotton in situ, and postcotton—to measure the reproducibility of ENS6Q scoring. Participants also completed a five-Item transition scale ranging from “much better” to “much worse” to rate subjective changes in nasal breathing with and without cotton placement. Mean changes for each transition point, and the ENS6Q MCID, were then calculated. Results In the precotton condition, significant differences (P < .001) in all ENS6Q questions between ENS and controls were noted. With cotton in situ, nearly all prior ENS6Q differences normalized between ENS and control patients. For ENS patients, the changes in the mean differences between the precotton and cotton in situ conditions compared to postcotton versus cotton in situ conditions were insignificant among individuals. Including all 33 participants, the mean change in the ENS6Q between the parameters “a little better” and “about the same” was 4.25 (standard deviation [SD] = 5.79) and −2.00 (SD = 3.70), giving an MCID of 6.25. Conclusions Cotton testing is a validated office test to assess for ENS patients. Cotton testing also helped to determine the MCID of the ENS6Q, which is a 7-point change from the baseline ENS6Q score. Level of Evidence 3b. Laryngoscope, 127:1746–1752, 2017

  • The Empty Nose Syndrome 6-Item Questionnaire (ENS6Q): a validated 6-Item Questionnaire as a diagnostic aid for empty nose syndrome patients.
    International forum of allergy & rhinology, 2016
    Co-Authors: Nathalia Velasquez, Andrew Thamboo, Al-rahim R. Habib, Zhenxiao Huang, Jayakar V. Nayak
    Abstract:

    Background Empty nose syndrome (ENS) is considered an acquired condition that remains difficult to diagnose objectively. Defining specific symptoms that can be reliably associated with this disorder would be essential to identifying possible ENS patients. We sought to validate an ENS-specific, 6-Item Questionnaire as an adjunct to the standard Sino-Nasal Outcome Test 22 (SNOT-22) Questionnaire to discriminate patients suspected of having ENS. Methods The Empty Nose Syndrome 6-Item Questionnaire (ENS6Q) paired 6 common ENS symptoms (nasal suffocation, nasal burning, nasal openness, crusting, dryness, and impaired air sensation through nasal cavities) with testing on 75 patients divided in 3 patient cohorts: ENS; chronic rhinosinusitis without polyposis; and healthy controls. Participants answered 2 rounds of both the SNOT-22 Questionnaire and ENS6Q within 48 hours of each other. No changes in treatments occurred in the test interval between Questionnaires. Internal consistency, test-retest reliability, validity, and area under the curve were assessed to differentiate between patient cohorts using the 2 instruments. Results We found high internal consistency for ENS6Q and SNOT-22 Questionnaire at 0.93 (95% CI, 0.90-0.95) and 0.94 (95% CI, 0.94-0.96), respectively. The test-retest reliability between timepoints for ENS6Q testing was 0.969. The ENS6Q statistically significantly discriminated between ENS and control patients and between ENS and chronic rhinosinusitis without polyposis (CRSsNP) patients, without significant differences between CRSsNP and controls. The area-under-the-curve (AUC) threshold score comparison further supported the ability of the ENS6Q to differentiate ENS from CRSsNP patients. Conclusion The ENS6Q is the first validated, specific, adjunct Questionnaire to the SNOT-22 to more reliably identify patients suspected of developing ENS.

Bo Nyström - One of the best experts on this subject based on the ideXlab platform.

Elisabeth Svensson - One of the best experts on this subject based on the ideXlab platform.

Jyoti Khadka - One of the best experts on this subject based on the ideXlab platform.

  • development of the 25 Item cardiff visual ability Questionnaire for children cvaqc
    British Journal of Ophthalmology, 2010
    Co-Authors: Jyoti Khadka, Barbara Ryan, Tom Margrain, Helen Court, Margaret J Woodhouse
    Abstract:

    Aims To develop and validate a short Questionnaire to assess self-reported visual ability in children and young people with a visual impairment. Methods A list of 121 Items was generated from 13 focus groups with children and young people with and without a visual impairment. A long 89-Item Questionnaire was piloted with 45 visually impaired children and young people using face-to-face interviews. Rasch analysis was used to analyse the response category function and to facilitate Item removal ensuring a valid unidimensional scale. The validity and reliability of the short Questionnaire were assessed on a group of 109 visually impaired children (58.7% boys; median age 13 years) using Rasch analysis and intraclass correlation coefficient (ICC). Results The final 25-Item Questionnaire has good validity and reliability as demonstrated by a person separation index of 2.28 and reliability coefficient of 0.84. The Items are well targeted to the subjects with a mean difference of −0.40 logit between Item and person means, and an ICC of 0.89 demonstrates good temporal stability. Conclusion The Cardiff Visual Ability Questionnaire for Children (CVAQC) is a short, psychometrically robust and a self-reported instrument that works to form a unidimensional scale for the assessment of the visual ability in children and young people with a visual impairment.

  • Development of the 25-Item Cardiff Visual Ability Questionnaire for Children (CVAQC)
    British Journal of Ophthalmology, 2010
    Co-Authors: Jyoti Khadka, Barbara Ryan, Tom Margrain, Helen Court, J Margaret Woodhouse
    Abstract:

    Aims: To develop and validate a short Questionnaire to assess self reported visual ability in children and young people with a visual impairment. Methods: A list of 121 Items was generated from 13 focus groups with children and young people with and without a visual impairment. A long 89 Item Questionnaire was piloted with 45 visually impaired children and young people using face to face interviews. Rasch analysis was used to analyze the response category function and to facilitate Item removal ensuring a valid unidimensional scale. The validity and reliability of the short Questionnaire were assessed on a group of 109 visually impaired children (58.7% boys; median age, 13 years) using Rasch analysis and intraclass correlation coefficient (ICC). Results: The final 25-Item Questionnaire has good validity and reliability as demonstrated by a person separation index of 2.28 and reliability coefficient of 0.84. The Items are well targeted to the subjects with a mean difference of -0.40 logit between Item and person means and ICC of 0.89 demonstrate a good temporal stability. Conclusion: The CVAQC is a short, psychometrically robust, self reported instrument which works to form a unidimensional scale for the assessment of the visual ability in children and young people with a visual impairment

Christelle Nguyen - One of the best experts on this subject based on the ideXlab platform.

  • Development of a new patient-reported outcome measure assessing activities and participation in people with lumbar spinal stenosis: the cochin spinal stenosis 19-Item Questionnaire.
    European journal of physical and rehabilitation medicine, 2020
    Co-Authors: Chiara Masi, Gaelle Couraud, C. Daste, Jennifer Jouffriault, Serge Poiraudeau, Marie-martine Lefèvre-colau, François Rannou, Christelle Nguyen
    Abstract:

    Background Lumbar spinal stenosis (LSS) is the leading cause of spinal surgery in people over 65-years old. In people with LSS, generic self-administered Questionnaires are the most commonly used PROs to assess health-related quality of life, global activity limitation, and low back pain-located activity limitation. Aim To develop of a new patient-reported outcome measure assessing activities and participation in people with LSS. Design Observation, prospective and qualitative study. Setting For the qualitative study, enrolled in- and outpatients with LSS from 2 French tertiary care centers (Department of PRM of Cochin Hospital and Department of Rheumatology of Limoges Hospital). For the Internet E-survey, screened the electronic medical records of the Department of PRM of Cochin Hospital. Population Enrolled from February to April 2018, patients older than 50-years and symptomatic LSS. Methods We used a 2 step approach. In a first step, we conducted a qualitative study using in-depth semi-structured interviews in 20 patients with LSS to collect meaningful concepts and to develop a provisional Questionnaire. In a second step, using the provisional Questionnaire, we conducted an Internet E-survey in an independent sample of 200 patients with LSS. Results Concepts collected from patients generated a 48-Item provisional Questionnaire. Overall, 63/200 (31.5%) patients completed the provisional Questionnaire. Item reduction resulted in a 19-Item Questionnaire, the Cochin Spinal Stenosis 19-Item (CSS-19) Questionnaire. Principal component analysis extracted 3 factors. In confirmatory analysis, factor 1 influenced all Items. We found convergent validity with low back pain, LSS-specific disability and divergent validity with mental health-related quality of life. Cronbach α coefficient (95% CI) was 0.96 (0.94;0.97). ICC was 0.90 (0.70;0.97). Bland and Altman analysis found no systematic trend for test-retest. Conclusions CSS-19 is a new patient-reported outcome measure assessing activities and participation in people with LSS. Its construction prioritized patients' perspectives at all stages. Its content and construct validities are good. Clinical rehabilitation impact Instruments able to capture specific needs of people with LSS in terms of activities and participation are lacking.