The Experts below are selected from a list of 2757 Experts worldwide ranked by ideXlab platform
Masaru Sugimachi - One of the best experts on this subject based on the ideXlab platform.
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A novel minimally-invasive technique to predict pulmonary capillary wedge Pressure utilizing Jugular Venous Pressure and the tissue Doppler tricuspid/mitral annular velocities
European Heart Journal, 2013Co-Authors: Kazunori Uemura, Toru Kawada, Masaru SugimachiAbstract:Purpose: Accurate prediction of left heart filling Pressure is critical to the management of patients with Heart Failure (HF). However, reliability of conventional prediction such as the ratio of early transmitral velocity to tissue Doppler mitral annular early diastolic velocity (E/Ea) is not satisfactory. Purpose of this study was to validate our newly developed technique to predict Pulmonary Capillary Wedge Pressure (PCWP) utilizing Jugular Venous Pressure (JVP) and the ratio of tissue Doppler peak systolic velocity of the tricuspid annulus (St) to that of the mitral annulus (Sm). Methods: In 10 anesthetized closed-chest dogs, PCWP and JVP were measured through catheters. St, Sm and E/Ea were measured by trans-thoracic tissue Doppler echocardiography. PCWP, JVP, St, Sm and E/Ea were recorded over a variable preload range in normal heart, in left HF induced by coronary artery embolization, and in right HF induced by pulmonary artery embolization. Results: Regression analysis of pooled 146 data sets indicated that PCWP (2–40 mmHg) and E/Ea (3–14) correlated weakly (Figure A), while PCWP and JVP·St/Sm (-1–32mmHg) correlated tightly (Figure B). Receiver-operating characteristic (ROC) analysis identified cutoffs that maximized the sum of sensitivity and specificity for detecting PCWP > 18 mmHg (Figure C). E/Ea >6 had 89% sensitivity and 73% specificity. JVP·St/Sm >11 mmHg had 90% sensitivity and 90% specificity. Area under ROC curve for JVP·St/Sm (0.94) was significantly larger than that for E/Ea (0.79) (p
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a novel minimally invasive technique to predict pulmonary capillary wedge Pressure utilizing Jugular Venous Pressure and the tissue doppler tricuspid mitral annular velocities
European Heart Journal, 2013Co-Authors: Kazunori Uemura, Toru Kawada, Masaru SugimachiAbstract:Purpose: Accurate prediction of left heart filling Pressure is critical to the management of patients with Heart Failure (HF). However, reliability of conventional prediction such as the ratio of early transmitral velocity to tissue Doppler mitral annular early diastolic velocity (E/Ea) is not satisfactory. Purpose of this study was to validate our newly developed technique to predict Pulmonary Capillary Wedge Pressure (PCWP) utilizing Jugular Venous Pressure (JVP) and the ratio of tissue Doppler peak systolic velocity of the tricuspid annulus (St) to that of the mitral annulus (Sm). Methods: In 10 anesthetized closed-chest dogs, PCWP and JVP were measured through catheters. St, Sm and E/Ea were measured by trans-thoracic tissue Doppler echocardiography. PCWP, JVP, St, Sm and E/Ea were recorded over a variable preload range in normal heart, in left HF induced by coronary artery embolization, and in right HF induced by pulmonary artery embolization. Results: Regression analysis of pooled 146 data sets indicated that PCWP (2–40 mmHg) and E/Ea (3–14) correlated weakly (Figure A), while PCWP and JVP·St/Sm (-1–32mmHg) correlated tightly (Figure B). Receiver-operating characteristic (ROC) analysis identified cutoffs that maximized the sum of sensitivity and specificity for detecting PCWP > 18 mmHg (Figure C). E/Ea >6 had 89% sensitivity and 73% specificity. JVP·St/Sm >11 mmHg had 90% sensitivity and 90% specificity. Area under ROC curve for JVP·St/Sm (0.94) was significantly larger than that for E/Ea (0.79) (p<0.001). ![Figure][1] Figure 1 Conclusions: JVP corrected by the relation between right and left ventricular functions, JVP·St/Sm, accurately predicts PCWP. Our technique to predict PCWP may be useful in the management of HF patients. [1]: pending:yes
Kazunori Uemura - One of the best experts on this subject based on the ideXlab platform.
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A novel minimally-invasive technique to predict pulmonary capillary wedge Pressure utilizing Jugular Venous Pressure and the tissue Doppler tricuspid/mitral annular velocities
European Heart Journal, 2013Co-Authors: Kazunori Uemura, Toru Kawada, Masaru SugimachiAbstract:Purpose: Accurate prediction of left heart filling Pressure is critical to the management of patients with Heart Failure (HF). However, reliability of conventional prediction such as the ratio of early transmitral velocity to tissue Doppler mitral annular early diastolic velocity (E/Ea) is not satisfactory. Purpose of this study was to validate our newly developed technique to predict Pulmonary Capillary Wedge Pressure (PCWP) utilizing Jugular Venous Pressure (JVP) and the ratio of tissue Doppler peak systolic velocity of the tricuspid annulus (St) to that of the mitral annulus (Sm). Methods: In 10 anesthetized closed-chest dogs, PCWP and JVP were measured through catheters. St, Sm and E/Ea were measured by trans-thoracic tissue Doppler echocardiography. PCWP, JVP, St, Sm and E/Ea were recorded over a variable preload range in normal heart, in left HF induced by coronary artery embolization, and in right HF induced by pulmonary artery embolization. Results: Regression analysis of pooled 146 data sets indicated that PCWP (2–40 mmHg) and E/Ea (3–14) correlated weakly (Figure A), while PCWP and JVP·St/Sm (-1–32mmHg) correlated tightly (Figure B). Receiver-operating characteristic (ROC) analysis identified cutoffs that maximized the sum of sensitivity and specificity for detecting PCWP > 18 mmHg (Figure C). E/Ea >6 had 89% sensitivity and 73% specificity. JVP·St/Sm >11 mmHg had 90% sensitivity and 90% specificity. Area under ROC curve for JVP·St/Sm (0.94) was significantly larger than that for E/Ea (0.79) (p
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a novel minimally invasive technique to predict pulmonary capillary wedge Pressure utilizing Jugular Venous Pressure and the tissue doppler tricuspid mitral annular velocities
European Heart Journal, 2013Co-Authors: Kazunori Uemura, Toru Kawada, Masaru SugimachiAbstract:Purpose: Accurate prediction of left heart filling Pressure is critical to the management of patients with Heart Failure (HF). However, reliability of conventional prediction such as the ratio of early transmitral velocity to tissue Doppler mitral annular early diastolic velocity (E/Ea) is not satisfactory. Purpose of this study was to validate our newly developed technique to predict Pulmonary Capillary Wedge Pressure (PCWP) utilizing Jugular Venous Pressure (JVP) and the ratio of tissue Doppler peak systolic velocity of the tricuspid annulus (St) to that of the mitral annulus (Sm). Methods: In 10 anesthetized closed-chest dogs, PCWP and JVP were measured through catheters. St, Sm and E/Ea were measured by trans-thoracic tissue Doppler echocardiography. PCWP, JVP, St, Sm and E/Ea were recorded over a variable preload range in normal heart, in left HF induced by coronary artery embolization, and in right HF induced by pulmonary artery embolization. Results: Regression analysis of pooled 146 data sets indicated that PCWP (2–40 mmHg) and E/Ea (3–14) correlated weakly (Figure A), while PCWP and JVP·St/Sm (-1–32mmHg) correlated tightly (Figure B). Receiver-operating characteristic (ROC) analysis identified cutoffs that maximized the sum of sensitivity and specificity for detecting PCWP > 18 mmHg (Figure C). E/Ea >6 had 89% sensitivity and 73% specificity. JVP·St/Sm >11 mmHg had 90% sensitivity and 90% specificity. Area under ROC curve for JVP·St/Sm (0.94) was significantly larger than that for E/Ea (0.79) (p<0.001). ![Figure][1] Figure 1 Conclusions: JVP corrected by the relation between right and left ventricular functions, JVP·St/Sm, accurately predicts PCWP. Our technique to predict PCWP may be useful in the management of HF patients. [1]: pending:yes
Vivek Muthurangu - One of the best experts on this subject based on the ideXlab platform.
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Pre-Operative Grade of Decompressing Systemic Venous Collaterals, But Not Jugular Venous Pressure, Predicts Short- and Medium-Term Outcome After Completion of the Total Cavopulmonary Connection.
JACC. Cardiovascular imaging, 2019Co-Authors: Marina Hughes, Michael Broadhead, Angus Mcewan, Oliver Tann, Sylvia Krupickova, Vivek MuthuranguAbstract:For pediatric patients with functionally single ventricles, cardiac magnetic resonance (CMR) imaging provides comprehensive interstage data before completion of total cavopulmonary connection (TCPC). Whether Jugular Venous Pressure (JVP) measured at CMR adds prognostic power has not been evaluated
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cardiac mr derived indices are stronger predictors of resource use and risk than Jugular Venous Pressure in paediatric patients with functionally single ventricles prior to completion of total cavopulmonary connection tcpc
Journal of Cardiovascular Magnetic Resonance, 2015Co-Authors: Marina Hughes, Michael Broadhead, Angus Mcewan, Oliver Tann, Sylvia Krupickova, Vivek Muthurangu, Troy E Dominguez, Andrew M TaylorAbstract:Methods Outcome data for all patients undergoing inter-stage pre-TCPC CMR between 2007-2014 was analysed. Predetermined outcome measures included survival, duration of peri-TCPC hospitalisation and TCPC fenestration. MRI was performed under general anaesthetic with simultaneous transduction of Jugular Venous Pressure (JVP), as per our Unit protocol. CMR-derived data included volumes and function of single ventricle, through-plane phase contrast flow volumes, contrast-enhanced angiography and 3D SSFP images. Flow was measured in ascending aorta, SVC, IVC, pulmonary arteries and pulmonary veins bilaterally. Thus systemic to pulmonary (S-P) collateral flow, net PA flow and SVC:IVC flow was quantified. 3D images allowed quantitative scoring of systemic veins off-loading the SVC system into IVC : 0= no SVC-IVC offloading veins seen, 1= few, small, low calibre veins, 2= large, obvious veins.
Toru Kawada - One of the best experts on this subject based on the ideXlab platform.
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A novel minimally-invasive technique to predict pulmonary capillary wedge Pressure utilizing Jugular Venous Pressure and the tissue Doppler tricuspid/mitral annular velocities
European Heart Journal, 2013Co-Authors: Kazunori Uemura, Toru Kawada, Masaru SugimachiAbstract:Purpose: Accurate prediction of left heart filling Pressure is critical to the management of patients with Heart Failure (HF). However, reliability of conventional prediction such as the ratio of early transmitral velocity to tissue Doppler mitral annular early diastolic velocity (E/Ea) is not satisfactory. Purpose of this study was to validate our newly developed technique to predict Pulmonary Capillary Wedge Pressure (PCWP) utilizing Jugular Venous Pressure (JVP) and the ratio of tissue Doppler peak systolic velocity of the tricuspid annulus (St) to that of the mitral annulus (Sm). Methods: In 10 anesthetized closed-chest dogs, PCWP and JVP were measured through catheters. St, Sm and E/Ea were measured by trans-thoracic tissue Doppler echocardiography. PCWP, JVP, St, Sm and E/Ea were recorded over a variable preload range in normal heart, in left HF induced by coronary artery embolization, and in right HF induced by pulmonary artery embolization. Results: Regression analysis of pooled 146 data sets indicated that PCWP (2–40 mmHg) and E/Ea (3–14) correlated weakly (Figure A), while PCWP and JVP·St/Sm (-1–32mmHg) correlated tightly (Figure B). Receiver-operating characteristic (ROC) analysis identified cutoffs that maximized the sum of sensitivity and specificity for detecting PCWP > 18 mmHg (Figure C). E/Ea >6 had 89% sensitivity and 73% specificity. JVP·St/Sm >11 mmHg had 90% sensitivity and 90% specificity. Area under ROC curve for JVP·St/Sm (0.94) was significantly larger than that for E/Ea (0.79) (p
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a novel minimally invasive technique to predict pulmonary capillary wedge Pressure utilizing Jugular Venous Pressure and the tissue doppler tricuspid mitral annular velocities
European Heart Journal, 2013Co-Authors: Kazunori Uemura, Toru Kawada, Masaru SugimachiAbstract:Purpose: Accurate prediction of left heart filling Pressure is critical to the management of patients with Heart Failure (HF). However, reliability of conventional prediction such as the ratio of early transmitral velocity to tissue Doppler mitral annular early diastolic velocity (E/Ea) is not satisfactory. Purpose of this study was to validate our newly developed technique to predict Pulmonary Capillary Wedge Pressure (PCWP) utilizing Jugular Venous Pressure (JVP) and the ratio of tissue Doppler peak systolic velocity of the tricuspid annulus (St) to that of the mitral annulus (Sm). Methods: In 10 anesthetized closed-chest dogs, PCWP and JVP were measured through catheters. St, Sm and E/Ea were measured by trans-thoracic tissue Doppler echocardiography. PCWP, JVP, St, Sm and E/Ea were recorded over a variable preload range in normal heart, in left HF induced by coronary artery embolization, and in right HF induced by pulmonary artery embolization. Results: Regression analysis of pooled 146 data sets indicated that PCWP (2–40 mmHg) and E/Ea (3–14) correlated weakly (Figure A), while PCWP and JVP·St/Sm (-1–32mmHg) correlated tightly (Figure B). Receiver-operating characteristic (ROC) analysis identified cutoffs that maximized the sum of sensitivity and specificity for detecting PCWP > 18 mmHg (Figure C). E/Ea >6 had 89% sensitivity and 73% specificity. JVP·St/Sm >11 mmHg had 90% sensitivity and 90% specificity. Area under ROC curve for JVP·St/Sm (0.94) was significantly larger than that for E/Ea (0.79) (p<0.001). ![Figure][1] Figure 1 Conclusions: JVP corrected by the relation between right and left ventricular functions, JVP·St/Sm, accurately predicts PCWP. Our technique to predict PCWP may be useful in the management of HF patients. [1]: pending:yes
Marina Hughes - One of the best experts on this subject based on the ideXlab platform.
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Pre-Operative Grade of Decompressing Systemic Venous Collaterals, But Not Jugular Venous Pressure, Predicts Short- and Medium-Term Outcome After Completion of the Total Cavopulmonary Connection.
JACC. Cardiovascular imaging, 2019Co-Authors: Marina Hughes, Michael Broadhead, Angus Mcewan, Oliver Tann, Sylvia Krupickova, Vivek MuthuranguAbstract:For pediatric patients with functionally single ventricles, cardiac magnetic resonance (CMR) imaging provides comprehensive interstage data before completion of total cavopulmonary connection (TCPC). Whether Jugular Venous Pressure (JVP) measured at CMR adds prognostic power has not been evaluated
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cardiac mr derived indices are stronger predictors of resource use and risk than Jugular Venous Pressure in paediatric patients with functionally single ventricles prior to completion of total cavopulmonary connection tcpc
Journal of Cardiovascular Magnetic Resonance, 2015Co-Authors: Marina Hughes, Michael Broadhead, Angus Mcewan, Oliver Tann, Sylvia Krupickova, Vivek Muthurangu, Troy E Dominguez, Andrew M TaylorAbstract:Methods Outcome data for all patients undergoing inter-stage pre-TCPC CMR between 2007-2014 was analysed. Predetermined outcome measures included survival, duration of peri-TCPC hospitalisation and TCPC fenestration. MRI was performed under general anaesthetic with simultaneous transduction of Jugular Venous Pressure (JVP), as per our Unit protocol. CMR-derived data included volumes and function of single ventricle, through-plane phase contrast flow volumes, contrast-enhanced angiography and 3D SSFP images. Flow was measured in ascending aorta, SVC, IVC, pulmonary arteries and pulmonary veins bilaterally. Thus systemic to pulmonary (S-P) collateral flow, net PA flow and SVC:IVC flow was quantified. 3D images allowed quantitative scoring of systemic veins off-loading the SVC system into IVC : 0= no SVC-IVC offloading veins seen, 1= few, small, low calibre veins, 2= large, obvious veins.
