The Experts below are selected from a list of 9 Experts worldwide ranked by ideXlab platform
A K Huber - One of the best experts on this subject based on the ideXlab platform.
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Nephroblastoma-like Kidney Adenoma: case report of an extremely rare Kidney tumor
Helvetica chirurgica acta, 1994Co-Authors: K M Raess, W Wegmann, A K HuberAbstract:The nephroblastoma-like Adenoma of the Kidney is an extremely rare tumor with similarities to the nephroblastoma (Wilm's tumor) of the adult. In the literature, different terms are applied to these lesions. We present the case of a 64-year-old woman who underwent a nephrectomy for suspicion of renal cell carcinoma. Histologically the tumor consisted of tubular and papillary formations of monomorphic tumor cells without mitoses or cell-atypias and showed no fibrous capsule. The differential diagnosis to the nephroblastoma of the adult was difficult. Immunohistochemically the tumor expressed the embryonic form of the neural cell adhesion molecule (N-CAM) interstitially and not in the epithelial tumor cell as seen in Wilm's tumor. For the biologic tumor-definition it is important to collect and follow these very rare cases.
K M Raess - One of the best experts on this subject based on the ideXlab platform.
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Nephroblastoma-like Kidney Adenoma: case report of an extremely rare Kidney tumor
Helvetica chirurgica acta, 1994Co-Authors: K M Raess, W Wegmann, A K HuberAbstract:The nephroblastoma-like Adenoma of the Kidney is an extremely rare tumor with similarities to the nephroblastoma (Wilm's tumor) of the adult. In the literature, different terms are applied to these lesions. We present the case of a 64-year-old woman who underwent a nephrectomy for suspicion of renal cell carcinoma. Histologically the tumor consisted of tubular and papillary formations of monomorphic tumor cells without mitoses or cell-atypias and showed no fibrous capsule. The differential diagnosis to the nephroblastoma of the adult was difficult. Immunohistochemically the tumor expressed the embryonic form of the neural cell adhesion molecule (N-CAM) interstitially and not in the epithelial tumor cell as seen in Wilm's tumor. For the biologic tumor-definition it is important to collect and follow these very rare cases.
W Wegmann - One of the best experts on this subject based on the ideXlab platform.
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Nephroblastoma-like Kidney Adenoma: case report of an extremely rare Kidney tumor
Helvetica chirurgica acta, 1994Co-Authors: K M Raess, W Wegmann, A K HuberAbstract:The nephroblastoma-like Adenoma of the Kidney is an extremely rare tumor with similarities to the nephroblastoma (Wilm's tumor) of the adult. In the literature, different terms are applied to these lesions. We present the case of a 64-year-old woman who underwent a nephrectomy for suspicion of renal cell carcinoma. Histologically the tumor consisted of tubular and papillary formations of monomorphic tumor cells without mitoses or cell-atypias and showed no fibrous capsule. The differential diagnosis to the nephroblastoma of the adult was difficult. Immunohistochemically the tumor expressed the embryonic form of the neural cell adhesion molecule (N-CAM) interstitially and not in the epithelial tumor cell as seen in Wilm's tumor. For the biologic tumor-definition it is important to collect and follow these very rare cases.
William H. Westra - One of the best experts on this subject based on the ideXlab platform.
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Metastasizing mixed tumor of the parotid: initial presentation as a solitary Kidney tumor and ultimate carcinomatous transformation at the primary site.
The American journal of surgical pathology, 2000Co-Authors: Magdalena Czader, Charles G. Eberhart, Nasir I. Bhatti, Charles W. Cummings, William H. WestraAbstract:Benign mixed tumors of the salivary glands are generally regarded as indolent and harmless neoplasms. A subset of benign mixed tumors, however, can undergo carcinomatous transformation (that is, carcinoma ex-mixed tumor). Even more rarely, a mixed tumor that is seemingly benign at the microscopic level will metastasize like a true carcinoma (that is, metastasizing mixed tumor [MZMT]). Despite the benign appearance of the metastatic implants, there is usually little doubt regarding their true nature and origin. Patients invariably have had a mixed tumor removed from the parotid or some other salivary gland, and metastatic spread is usually preceded by multiple episodes of local tumor recurrence. We report a case of MZMT that presented as a solitary Kidney mass. In the absence of a previous or concurrent salivary gland tumor, its metastatic nature was not appreciated and it was regarded as an unusual but benign Kidney Adenoma. One year after removal of the Kidney mass, the patient presented with signs and symptoms of an aggressive parotid tumor. Pathologic examination of the tumor in the parotid demonstrated a high-grade carcinoma arising from a mixed tumor. This case underscores the importance of considering MZMT when a seemingly benign mixed tumor is encountered at a nonsalivary site, even in patients without a supportive history. Failure to do so may cause an unnecessary delay in primary tumor diagnosis and management, allow the primary tumor to progress toward a more malignant phenotype, and deny the patient a high expectation for a complete cure.
Magdalena Czader - One of the best experts on this subject based on the ideXlab platform.
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Metastasizing mixed tumor of the parotid: initial presentation as a solitary Kidney tumor and ultimate carcinomatous transformation at the primary site.
The American journal of surgical pathology, 2000Co-Authors: Magdalena Czader, Charles G. Eberhart, Nasir I. Bhatti, Charles W. Cummings, William H. WestraAbstract:Benign mixed tumors of the salivary glands are generally regarded as indolent and harmless neoplasms. A subset of benign mixed tumors, however, can undergo carcinomatous transformation (that is, carcinoma ex-mixed tumor). Even more rarely, a mixed tumor that is seemingly benign at the microscopic level will metastasize like a true carcinoma (that is, metastasizing mixed tumor [MZMT]). Despite the benign appearance of the metastatic implants, there is usually little doubt regarding their true nature and origin. Patients invariably have had a mixed tumor removed from the parotid or some other salivary gland, and metastatic spread is usually preceded by multiple episodes of local tumor recurrence. We report a case of MZMT that presented as a solitary Kidney mass. In the absence of a previous or concurrent salivary gland tumor, its metastatic nature was not appreciated and it was regarded as an unusual but benign Kidney Adenoma. One year after removal of the Kidney mass, the patient presented with signs and symptoms of an aggressive parotid tumor. Pathologic examination of the tumor in the parotid demonstrated a high-grade carcinoma arising from a mixed tumor. This case underscores the importance of considering MZMT when a seemingly benign mixed tumor is encountered at a nonsalivary site, even in patients without a supportive history. Failure to do so may cause an unnecessary delay in primary tumor diagnosis and management, allow the primary tumor to progress toward a more malignant phenotype, and deny the patient a high expectation for a complete cure.
