The Experts below are selected from a list of 2637 Experts worldwide ranked by ideXlab platform
Davood Toghraie - One of the best experts on this subject based on the ideXlab platform.
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The thermal performance of five different viscosity models in the Kidney Blood Vessel with multi-phase mixture of non-Newtonian fluid models using computational fluid dynamics
Archive of Applied Mechanics, 2021Co-Authors: Shahab Naghdi Sedeh, Davood ToghraieAbstract:Computational hemodynamic (CHD) is an engineering tool and a good approach that helped many physicians to obtain much information about the situation of the patient in a lot of diseases like cardiovascular disease, even surgery, etc. The dispersion of Blood cells in the plasma is heterogeneous. Therefore, the Blood fluid is a multi-phase mixture of non-Newtonian fluid. Numerical calculation of non-Newtonian viscosity models of Blood flow parameter includes Reynolds number; different wall heat fluxes in three situations of the body (sleeping, standing and running), etc. are investigated. To construct a 3D model of the Kidney Blood Vessel, an open-source software program using Digital Imaging and Communications in Medicine (DICOM) and Magnetic Resonance Image (MRI) is used. Additionally, the Vessel wall is considered solid. The finite volume approach and SIMPLE scheme are used. The non-Newtonian Blood flow is considered as a laminar flow. All of these heat fluxes generated by the body in different situations have their impact on the reported parameters in this paper. The reported parameters included dimensionless numbers like pressure drop, average wall shear stress, heat transfer coefficient, and temperature. The power-law non-Newtonian viscosity model makes the velocity gradient more than other non-Newtonian viscosity models. Also, the power-law model represents a higher heat transfer.
Shahab Naghdi Sedeh - One of the best experts on this subject based on the ideXlab platform.
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The thermal performance of five different viscosity models in the Kidney Blood Vessel with multi-phase mixture of non-Newtonian fluid models using computational fluid dynamics
Archive of Applied Mechanics, 2021Co-Authors: Shahab Naghdi Sedeh, Davood ToghraieAbstract:Computational hemodynamic (CHD) is an engineering tool and a good approach that helped many physicians to obtain much information about the situation of the patient in a lot of diseases like cardiovascular disease, even surgery, etc. The dispersion of Blood cells in the plasma is heterogeneous. Therefore, the Blood fluid is a multi-phase mixture of non-Newtonian fluid. Numerical calculation of non-Newtonian viscosity models of Blood flow parameter includes Reynolds number; different wall heat fluxes in three situations of the body (sleeping, standing and running), etc. are investigated. To construct a 3D model of the Kidney Blood Vessel, an open-source software program using Digital Imaging and Communications in Medicine (DICOM) and Magnetic Resonance Image (MRI) is used. Additionally, the Vessel wall is considered solid. The finite volume approach and SIMPLE scheme are used. The non-Newtonian Blood flow is considered as a laminar flow. All of these heat fluxes generated by the body in different situations have their impact on the reported parameters in this paper. The reported parameters included dimensionless numbers like pressure drop, average wall shear stress, heat transfer coefficient, and temperature. The power-law non-Newtonian viscosity model makes the velocity gradient more than other non-Newtonian viscosity models. Also, the power-law model represents a higher heat transfer.
Zheng Jidon - One of the best experts on this subject based on the ideXlab platform.
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giant Kidney Blood Vessel adipose tumor ct diagnosis and distinction diagnosis
人人健康(医学导刊), 2007Co-Authors: Zheng JidonAbstract:goal:Discusses the giant Kidney Blood Vessel adipose tumor the CT diagnosis and the distinction.Method:The giant Kidney Blood Vessel adipose tumor CT diagnosis and the distinction diagnosis which confirmed after the surgery carries on the review analysis to 10 examples.Finally:6 examples are the lump internal hemorrhage,the lump body suddenly increase,the intrinsic pressure increases but the prominent abdominal pain;4 examples for tumor extroversion growth.So long as in the discovery Kidney tumor has the fat density,the CT value below-40Hu,the enhancement scanning fat ingredient does not strengthen,the Blood Vessel muscular tissue strengthens may diagnose.Conclusion:CT is diagnoses the Kidney Blood Vessel adipose tumor the reliable method.
Oxburgh Leif - One of the best experts on this subject based on the ideXlab platform.
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Scaffolding Kidney organoids on silk.
MaineHealth Knowledge Connection, 2019Co-Authors: Gupta, Ashwani Kumar, Coburn, Jeannine M, Davis-knowlton Jessica, Kimmerling Erica, Kaplan, David L, Oxburgh LeifAbstract:End stage Kidney disease affects hundreds of thousands of patients in the United States. The therapy of choice is Kidney replacement, but availability of organs is limited, and alternative sources of tissue are needed. Generation of new Kidney tissue in the laboratory has been made possible through pluripotent cell reprogramming and directed differentiation. In current procedures, aggregates of cells known as organoids are grown either submerged or at the air-liquid interface. These studies have demonstrated that Kidney tissue can be generated from pluripotent stem cells, but they also identify limitations. The first is that perfusion of cell aggregates is limited, restricting the size to which they can be grown. The second is that aggregates lack the structural integrity required for convenient engraftment and suturing or adhesion to regions of Kidney injury. In this study, we evaluated the capacity of silk to serve as a support for the growth and differentiation of Kidney tissue from primary cells and from human induced pluripotent stem cells. We find that cells can differentiate to epithelia characteristic of the developing Kidney on this material and that these structures are maintained following engraftment under the capsule of the adult Kidney. Blood Vessel investment can be promoted by the addition of vascular endothelial growth factor to the scaffold, but the proliferation of stromal cells within the graft presents a challenge, which will require some readjustment of cell growth and differentiation conditions. In summary, we find that silk can be used to support growth of stem cell derived Kidney tissue
Gupta, Ashwani Kumar - One of the best experts on this subject based on the ideXlab platform.
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Scaffolding Kidney organoids on silk.
MaineHealth Knowledge Connection, 2019Co-Authors: Gupta, Ashwani Kumar, Coburn, Jeannine M, Davis-knowlton Jessica, Kimmerling Erica, Kaplan, David L, Oxburgh LeifAbstract:End stage Kidney disease affects hundreds of thousands of patients in the United States. The therapy of choice is Kidney replacement, but availability of organs is limited, and alternative sources of tissue are needed. Generation of new Kidney tissue in the laboratory has been made possible through pluripotent cell reprogramming and directed differentiation. In current procedures, aggregates of cells known as organoids are grown either submerged or at the air-liquid interface. These studies have demonstrated that Kidney tissue can be generated from pluripotent stem cells, but they also identify limitations. The first is that perfusion of cell aggregates is limited, restricting the size to which they can be grown. The second is that aggregates lack the structural integrity required for convenient engraftment and suturing or adhesion to regions of Kidney injury. In this study, we evaluated the capacity of silk to serve as a support for the growth and differentiation of Kidney tissue from primary cells and from human induced pluripotent stem cells. We find that cells can differentiate to epithelia characteristic of the developing Kidney on this material and that these structures are maintained following engraftment under the capsule of the adult Kidney. Blood Vessel investment can be promoted by the addition of vascular endothelial growth factor to the scaffold, but the proliferation of stromal cells within the graft presents a challenge, which will require some readjustment of cell growth and differentiation conditions. In summary, we find that silk can be used to support growth of stem cell derived Kidney tissue
