The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform
Glen Livingston - One of the best experts on this subject based on the ideXlab platform.
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The Kruskal–Wallis Tests are Cochran–Mantel–Haenszel mean score Tests
METRON, 2020Co-Authors: J. C. W. Rayner, Glen LivingstonAbstract:The Kruskal–Wallis Tests are appropriate Tests for the completely randomised design, both for when the data are untied ranks, and, with adjustment, for when there are ties and mid-ranks are used. Both these Tests are shown to be Cochran–Mantel–Haenszel mean score Tests. The relationship between the Kruskal–Wallis Test statistic and the ANOVA F Test statistic when there are no ties generalises to the same relationship between the Cochran–Mantel–Haenszel mean score Test statistic and the ANOVA F Test statistic. It thus also relates both Kruskal–Wallis Test statistics to the ANOVA F Test statistic. A small simulation study finds that p-values may be more accurately found using the F Test.
Klara Ajeng Canyarasmi - One of the best experts on this subject based on the ideXlab platform.
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Film Story Structure and Shot Type Analysis Using One-Way ANOVA, Kruskal–Wallis Test, and Poisson Distribution Test
Mathematics and Computing, 2015Co-Authors: Udjianna S. Pasaribu, Klara Ajeng CanyarasmiAbstract:Film is a popular media of storytelling nowadays and is commonly considered as a social and art study subject. In fact, AOF can be observed mathematically such as the shot type usage as a sequence of random event, and on how a film’s story adapts a particular story structure, in this case the Arch Plot Structure (APS). This study can be considered as one of the pioneering mathematical film studies. Three Indonesian children education themed movies are studied here. For the plot structure study, five ranked values were created to quantify the qualitative data. One-way ANOVA and Kruskal–Wallis Test were used to study whether each film followed APS For the shot type study, four ranked values were created. Further, as a sequence of random events, the Poisson distribution is applied to fit to the shot type usage of each observed film.
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film story structure and shot type analysis using one way anova Kruskal Wallis Test and poisson distribution Test
2015Co-Authors: Udjianna S. Pasaribu, Klara Ajeng CanyarasmiAbstract:Film is a popular media of storytelling nowadays and is commonly considered as a social and art study subject. In fact, AOF can be observed mathematically such as the shot type usage as a sequence of random event, and on how a film’s story adapts a particular story structure, in this case the Arch Plot Structure (APS). This study can be considered as one of the pioneering mathematical film studies. Three Indonesian children education themed movies are studied here. For the plot structure study, five ranked values were created to quantify the qualitative data. One-way ANOVA and Kruskal–Wallis Test were used to study whether each film followed APS For the shot type study, four ranked values were created. Further, as a sequence of random events, the Poisson distribution is applied to fit to the shot type usage of each observed film.
Simonetta Tagliavini - One of the best experts on this subject based on the ideXlab platform.
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Glycosylation Pattern and in vitro Bioactivity of Reference Follitropin alfa and Biosimilars
Frontiers in Endocrinology, 2019Co-Authors: Maria Teresa Villani, Laura Riccetti, Samantha Sperduti, Clara Lazzaretti, Danièle Klett, Francesco De Pascali, Elia Paradiso, Silvia Limoncella, Francesco Potì, Simonetta TagliaviniAbstract:Recombinant follicle-stimulating hormone (FSH) (follitropin alfa) and biosimilar preparations are available for clinical use. They have specific FSH activity and a unique glycosylation profile dependent on source cells. The aim of the study is to compare the originator (reference) follitropin alfa (Gonal-f®)- with biosimilar preparations (Bemfola® and Ovaleap®)-induced cellular responses in vitro. Gonadotropin N-glycosylation profiles were analyzed by ELISA lectin assay, revealing preparation specific-patterns of glycan species (Kruskal-Wallis Test; p < 0.05, n = 6) and by glycotope mapping. Increasing concentrations of Gonal-f® or biosimilar (1 × 10−3-1 × 103 ng/ml) were used for treating human primary granulosa lutein cells (hGLC) and FSH receptor (FSHR)-transfected HEK293 cells in vitro. Intracellular cAMP production, Ca2+ increase and β-arrestin 2 recruitment were evaluated by BRET, CREB, and ERK1/2 phosphorylation by Western blotting. 12-h gene expression, and 8- and 24-h progesterone and estradiol synthesis were measured by real-time PCR and immunoassay, respectively. We found preparation-specific glycosylation patterns by lectin assay (Kruskal-Wallis Test; p < 0.001; n = 6), and similar cAMP production and β-arrestin 2 recruitment in FSHR-transfected HEK293 cells (cAMP EC50 range = 12 ± 0.9–24 ± 1.7 ng/ml; β-arrestin 2 EC50 range = 140 ± 14.1–313 ± 18.7 ng/ml; Kruskal-Wallis Test; p ≥ 0.05; n = 4). Kinetics analysis revealed that intracellular Ca2+ increased upon cell treatment by 4 μg/ml Gonal-f®, while equal concentrations of biosimilars failed to induced a response (Kruskal-Wallis Test; p < 0.05; n = 3). All preparations induced both 8 and 24 h-progesterone and estradiol synthesis in hGLC, while no different EC50s were demonstrated (Kruskal-Wallis Test; p > 0.05; n = 5). Apart from preparation-specific intracellular Ca2+ increases achieved at supra-physiological hormone doses, all compounds induced similar intracellular responses and steroidogenesis, reflecting similar bioactivity, and overall structural homogeneity.
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Glycosylation Pattern and in vitro Bioactivity of Reference Follitropin alfa and Biosimilars
Frontiers in Endocrinology, 2019Co-Authors: Laura Riccetti, Samantha Sperduti, Clara Lazzaretti, Danièle Klett, Francesco De Pascali, Elia Paradiso, Silvia Limoncella, Francesco Potì, Simonetta Tagliavini, Tommaso TrentiAbstract:Recombinant follicle-stimulating hormone (FSH) (follitropin alfa) and biosimilar preparations are available for clinical use. They have specific FSH activity and a unique glycosylation profile dependent on source cells. The aim of the study is to compare the originator (reference) follitropin alfa (Gonal-f ®)-with biosimilar preparations (Bemfola ® and Ovaleap ®)-induced cellular responses in vitro. Gonadotropin N-glycosylation profiles were analyzed by ELISA lectin assay, revealing preparation specific-patterns of glycan species (Kruskal-Wallis Test; p < 0.05, n = 6) and by glycotope mapping. Increasing concentrations of Gonal-f ® or biosimilar (1 × 10 −3-1 × 10 3 ng/ml) were used for treating human primary granulosa lutein cells (hGLC) and FSH receptor (FSHR)-transfected HEK293 cells in vitro. Intracellular cAMP production, Ca 2+ increase and β-arrestin 2 recruitment were evaluated by BRET, CREB, and ERK1/2 phosphorylation by Western blotting. 12-h gene expression, and 8-and 24-h progesterone and estradiol synthesis were measured by real-time PCR and immunoassay, respectively. We found preparation-specific glycosylation patterns by lectin assay (Kruskal-Wallis Test; p < 0.001; n = 6), and similar cAMP production and β-arrestin 2 recruitment in FSHR-transfected HEK293 cells (cAMP EC 50 range = 12 ± 0.9-24 ± 1.7 ng/ml; β-arrestin 2 EC 50 range = 140 ± 14.1-313 ± 18.7 ng/ml; Kruskal-Wallis Test; p ≥ 0.05; n = 4). Kinetics analysis revealed that intracellular Ca 2+ increased upon cell treatment by 4 µg/ml Gonal-f ® , while equal concentrations of biosimilars failed to induced a response (Kruskal-Wallis Test; p < 0.05; n = 3). All preparations induced both 8 and 24 h-progesterone and estradiol synthesis in hGLC, while no different EC 50 s were
J. C. W. Rayner - One of the best experts on this subject based on the ideXlab platform.
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The Kruskal–Wallis Tests are Cochran–Mantel–Haenszel mean score Tests
METRON, 2020Co-Authors: J. C. W. Rayner, Glen LivingstonAbstract:The Kruskal–Wallis Tests are appropriate Tests for the completely randomised design, both for when the data are untied ranks, and, with adjustment, for when there are ties and mid-ranks are used. Both these Tests are shown to be Cochran–Mantel–Haenszel mean score Tests. The relationship between the Kruskal–Wallis Test statistic and the ANOVA F Test statistic when there are no ties generalises to the same relationship between the Cochran–Mantel–Haenszel mean score Test statistic and the ANOVA F Test statistic. It thus also relates both Kruskal–Wallis Test statistics to the ANOVA F Test statistic. A small simulation study finds that p-values may be more accurately found using the F Test.
Gail Fahoome - One of the best experts on this subject based on the ideXlab platform.
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Wiley StatsRef: Statistics Reference Online - Kruskal-Wallis Test: Basic†
Wiley StatsRef: Statistics Reference Online, 2014Co-Authors: Shlomo S Sawilowsky, Gail FahoomeAbstract:The nonparametric Kruskal-Wallis Test is an extension of the Wilcoxon-Mann-Whitney Test. The null hypothesis is that the k populations sampled have the same average (median). The alternative hypothesis is that at least one sample is from a distribution with a different average (median). This Test is an alternative to the parametric one-way analysis of variance F Test. Keywords: k-sample Tests; one-way ANOVA; Wilcoxon-Mann-Whitney Test
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Kruskal Wallis Test basic
Wiley StatsRef: Statistics Reference Online, 2014Co-Authors: Shlomo S Sawilowsky, Gail FahoomeAbstract:The nonparametric Kruskal-Wallis Test is an extension of the Wilcoxon-Mann-Whitney Test. The null hypothesis is that the k populations sampled have the same average (median). The alternative hypothesis is that at least one sample is from a distribution with a different average (median). This Test is an alternative to the parametric one-way analysis of variance F Test. Keywords: k-sample Tests; one-way ANOVA; Wilcoxon-Mann-Whitney Test
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Kruskal Wallis Test
Encyclopedia of Statistics in Behavioral Science, 2005Co-Authors: Shlomo S Sawilowsky, Gail FahoomeAbstract:The nonparametric Kruskal-Wallis Test is an extension of the Wilcoxon-Mann-Whitney Test. The null hypothesis is that the k populations sampled have the same average (median). The alternative hypothesis is that at least one sample is from a distribution with a different average (median). This Test is an alternative to the parametric one-way analysis of variance F Test. Keywords: k-sample Tests; one-way ANOVA; Wilcoxon-Mann-Whitney Test
