The Experts below are selected from a list of 1395 Experts worldwide ranked by ideXlab platform
Paul Brown - One of the best experts on this subject based on the ideXlab platform.
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Kuru the first prion Disease
2012Co-Authors: Pawel P Liberski, Beata Sikorska, Paul BrownAbstract:Kuru Disease is linked with the name of D. Carleton Gajdusek and he was the first to show that this human neurodegenerative Disease can be transmitted to chimpanzees and subsequently classified as a transmissible spongiform encephalopathy (TSE), or slow unconventional virus Disease. It was first reported to Western world in 1957 by Gajdusek and Vincent Zigas,1,2 and in 1975 a complete bibliography of Kuru was published by Alpers et al.3 “Kuru” in the Fore language in Papua New Guinea means to shiver from fever and cold. The Disease has been found to spread through ritualistic cannibalism and is an invariably fatal cerebellar ataxia accompanied by tremor, choreiform and athetoid movements. Neuropathologically, Kuru is characterized by the presence of amyloid “Kuru” plaques.
Pawel P Liberski - One of the best experts on this subject based on the ideXlab platform.
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Kuru the first prion Disease
2012Co-Authors: Pawel P Liberski, Beata Sikorska, Paul BrownAbstract:Kuru Disease is linked with the name of D. Carleton Gajdusek and he was the first to show that this human neurodegenerative Disease can be transmitted to chimpanzees and subsequently classified as a transmissible spongiform encephalopathy (TSE), or slow unconventional virus Disease. It was first reported to Western world in 1957 by Gajdusek and Vincent Zigas,1,2 and in 1975 a complete bibliography of Kuru was published by Alpers et al.3 “Kuru” in the Fore language in Papua New Guinea means to shiver from fever and cold. The Disease has been found to spread through ritualistic cannibalism and is an invariably fatal cerebellar ataxia accompanied by tremor, choreiform and athetoid movements. Neuropathologically, Kuru is characterized by the presence of amyloid “Kuru” plaques.
Beata Sikorska - One of the best experts on this subject based on the ideXlab platform.
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Kuru the first prion Disease
2012Co-Authors: Pawel P Liberski, Beata Sikorska, Paul BrownAbstract:Kuru Disease is linked with the name of D. Carleton Gajdusek and he was the first to show that this human neurodegenerative Disease can be transmitted to chimpanzees and subsequently classified as a transmissible spongiform encephalopathy (TSE), or slow unconventional virus Disease. It was first reported to Western world in 1957 by Gajdusek and Vincent Zigas,1,2 and in 1975 a complete bibliography of Kuru was published by Alpers et al.3 “Kuru” in the Fore language in Papua New Guinea means to shiver from fever and cold. The Disease has been found to spread through ritualistic cannibalism and is an invariably fatal cerebellar ataxia accompanied by tremor, choreiform and athetoid movements. Neuropathologically, Kuru is characterized by the presence of amyloid “Kuru” plaques.
Yi Weng - One of the best experts on this subject based on the ideXlab platform.
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from the scrapie syndrome of sheep and goat to the mad cow Disease the history of the discovery of prion
2009Co-Authors: Rui Liu, Yi WengAbstract:Since the discovery of Scrapie Syndrome in sheep and goats in 1730, there emerged a series of Diseases such as Creutzfeldt-Jakob Disease, Kuru Disease and mad cow Disease etc. In the research of Kuru Disease, the American scientist D. Carlteton Gajdusek found a new virus without the characteristic of DNA and RNA, which was awarded the Nobel Prize in physiology in 1976. Since then another American scientist, Stanley B. Prusiner, found a new virus-prion, taking protein as the genetic medium, which was awarded the Nobel prize in physiology and medicine in 1997. The discovery of prion is a great landmark in the research of life science, which laid a theoretical foundation for people to conquer a series of Diseases such as Scrapie syndrome in sheep and goats, Creutzfeldt-Jakob Disease, Kuru Disease and mad cow Disease etc.
Rui Liu - One of the best experts on this subject based on the ideXlab platform.
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from the scrapie syndrome of sheep and goat to the mad cow Disease the history of the discovery of prion
2009Co-Authors: Rui Liu, Yi WengAbstract:Since the discovery of Scrapie Syndrome in sheep and goats in 1730, there emerged a series of Diseases such as Creutzfeldt-Jakob Disease, Kuru Disease and mad cow Disease etc. In the research of Kuru Disease, the American scientist D. Carlteton Gajdusek found a new virus without the characteristic of DNA and RNA, which was awarded the Nobel Prize in physiology in 1976. Since then another American scientist, Stanley B. Prusiner, found a new virus-prion, taking protein as the genetic medium, which was awarded the Nobel prize in physiology and medicine in 1997. The discovery of prion is a great landmark in the research of life science, which laid a theoretical foundation for people to conquer a series of Diseases such as Scrapie syndrome in sheep and goats, Creutzfeldt-Jakob Disease, Kuru Disease and mad cow Disease etc.
