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Keita Ito - One of the best experts on this subject based on the ideXlab platform.

  • an in vitro investigation of the acetabular labral seal in hip joint mechanics
    Journal of Biomechanics, 2003
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    Labrum pathology may contribute to early joint degeneration through the alteration of load transfer between, and the stresses within, the cartilage layers of the hip. We hypothesize that the labrum seals the hip joint, creating a hydrostatic fluid pressure in the intra-articular space, and limiting the rate of cartilage layer consolidation. The overall cartilage creep consolidation of six human hip joints was measured during the application of a constant load of 0.75 times bodyweight, or a cyclic sinusoidal load of 0.75±0.25 times bodyweight, before and after total labrum resection. The fluid pressure within the acetabular was measured. Following labrum resection, the initial consolidation rate was 22% greater (p=0.02) and the final consolidation displacement was 21% greater (p=0.02). There was no significant difference in the final consolidation rate. Loading type (constant vs. cyclic) had no significant effect on the measured consolidation behaviour. Fluid pressurisation was observed in three of the six hips. The average pressures measured were: for constant loading, 541±61 kPa in the intact joint and 216±165 kPa following labrum resection, for cyclic loading, 550±56 kPa in the intact joint and 195±145 kPa following labrum resection. The trends observed in this experiment support the predictions of previous finite element analyses. Hydrostatic fluid pressurisation within the intra-articular space is greater with the labrum than without, which may enhance joint lubrication. Cartilage consolidation is quicker without the labrum than with, as the labrum adds an extra resistance to the flow path for interstitial fluid expression. However, both sealing mechanisms are dependent on the fit of the labrum against the femoral head.

  • the influence of the acetabular labrum on hip joint cartilage consolidation a poroelastic finite element model
    Journal of Biomechanics, 2000
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    The goal of this study was to investigate the influence of the acetabular labrum on the consolidation, and hence the solid matrix strains and stresses, of the cartilage layers of the hip joint. A plane-strain finite element model was developed, which represented a coronal slice through the acetabular and femoral cartilage layers and the acetabular labrum. Elements with poroelastic properties were used to account for the biphasic solid/fluid nature of the cartilage and labrum. The response of the joint over an extended period of loading (10,000s) was examined to simulate the nominal compressive load that the joint is subjected to throughout the day. The model demonstrated that the labrum adds an important resistance in the flow path of the fluid being expressed from the cartilage layers of the joint. Cartilage layer consolidation was up to 40% quicker in the absence of the labrum. Following removal of the labrum from the model, the solid-on-solid contact stresses between the femoral and acetabular cartilage layers were greatly increased (up to 92% higher), which would increase the friction between the joint surfaces. In the absence of the labrum, the centre of contact shifted towards the acetabular rim. Subsurface strains and stresses were much higher without the labrum, which could contribute to fatigue damage of the cartilage layers. Finally, the labrum provided some structural resistance to lateral motion of the femoral head within the acetabulum, enhancing joint stability and preserving joint congruity.

  • the influence of the acetabular labrum on hip joint cartilage consolidation a poroelastic finite element model
    Journal of Biomechanics, 2000
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    The goal of this study was to investigate the in#uence of the acetabular labrum on the consolidation, and hence the solid matrix strains and stresses, of the cartilage layers of the hip joint. A plane-strain "nite element model was developed, which represented a coronal slice through the acetabular and femoral cartilage layers and the acetabular labrum. Elements with poroelastic properties were used to account for the biphasic solid/#uid nature of the cartilage and labrum. The response of the joint over an extended period of loading (10,000 s) was examined to simulate the nominal compressive load that the joint is subjected to throughout the day. The model demonstrated that the labrum adds an important resistance in the #ow path of the #uid being expressed from the cartilage layers of the joint. Cartilage layer consolidation was up to 40% quicker in the absence of the labrum. Following removal of the labrum from the model, the solid-on-solid contact stresses between the femoral and acetabular cartilage layers were greatly increased (up to 92% higher), which would increase the friction between the joint surfaces. In the absence of the labrum, the centre of contact shifted towards the acetabular rim. Subsurface strains and stresses were much higher without the labrum, which could contribute to fatigue damage of the cartilage layers. Finally, the labrum provided some structural resistance to lateral motion of the femoral head within the acetabulum, enhancing joint stability and preserving joint congruity. ( 2000 Elsevier Science Ltd. All rights reserved.

  • the acetabular labrum seal a poroelastic finite element model
    Clinical Biomechanics, 2000
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    Objective. The aim of the study is to investigate the labrum’s ability to seal a pressurised layer of synovial fluid within the joint, and to study the influence of this sealing mechanism on cartilage deformation, interstitial fluid pressure and collagen solid matrix stresses. Background. Cartilage degeneration has been observed in conjunction with labrum pathology. However, little is known about the function of the labrum. Experimental observations have been reported which are consistent with a sealing function of the labrum. Methods. The model was an axisymmetric geometric approximation of the acetabular and femoral cartilage layers and the surrounding labrum. A poroelastic formulation was used to account for the solid and fluid components of these hydrated tissues. A sensitivity analysis of the labrum material properties was carried out. Results. With a compressive load of 1200 N applied across the joint model, the labrum could seal a layer of pressurised fluid between the femur and acetabulum, thus preventing contact of the articulating surfaces. With this sealing effect, loads were transferred across the joint predominantly by uniform pressurisation of the interstitial fluid of the cartilage layers. In the absence of this sealing, strains within the solid matrix of the cartilage layers were higher (e.g. 20% vs. 3%). Conclusions. The labrum can seal against fluid expression from the joint space. This sealing function protects the cartilage layers of the hip. Relevance Current treatments for labrum damage and early arthrosis may compromise the sealing function of the labrum. With continued study of the function and importance of the labrum, new surgical repair strategies can be developed to maintain the overall function of the hip joint.

Reinhold Ganz - One of the best experts on this subject based on the ideXlab platform.

  • magnetic resonance arthrography of labral disorders in hips with dysplasia and impingement
    Clinical Orthopaedics and Related Research, 2004
    Co-Authors: Michael Leunig, David A Podeszwa, Martin Beck, Stefan Werlen, Reinhold Ganz
    Abstract:

    Despite the fact that classic studies on osteoarthritis of the hip have shown the periphery of the hip to be prone to degeneration, it was not until recently that an abnormal acetabular labrum has been associated with osteoarthritis. This study was designed to determine whether magnetic resonance arthrography can show differences in disorders of the labrum (tears, size, ganglion formation) expected in symptomatic patients with developmental dysplasia of the hip and anterior femoroacetabular impingement. Fourteen patients in each group were evaluated preoperatively not only clinically but also with conventional radiographs and magnetic resonance arthrographs. In both conditions, disorders of the labrum localized identically with a predilection to the anterosuperior quadrant of the acetabulum. Labral tears were observed in nine hips of each group. The labrum was enlarged in 12 hips with dysplasia but in none of the hips with impingement. Ganglion formation in the periacetabular area was seen in 10 hips with dysplasia and three hips with impingement. These findings provide evidence that the anterosuperior acetabulum represents the initial fatiguing site of the hip under both conditions. Based on these data, the size of the labrum and the presence of soft tissue ganglia seem to be good predictors for the presence of developmental dysplasia, whereas the presence of tears did not differentiate between conditions. The capability of magnetic resonance arthrography to show these differences in labral disorders suggests this method is a helpful diagnostic tool that can aid in defining the most appropriate treatment strategy.

  • an in vitro investigation of the acetabular labral seal in hip joint mechanics
    Journal of Biomechanics, 2003
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    Labrum pathology may contribute to early joint degeneration through the alteration of load transfer between, and the stresses within, the cartilage layers of the hip. We hypothesize that the labrum seals the hip joint, creating a hydrostatic fluid pressure in the intra-articular space, and limiting the rate of cartilage layer consolidation. The overall cartilage creep consolidation of six human hip joints was measured during the application of a constant load of 0.75 times bodyweight, or a cyclic sinusoidal load of 0.75±0.25 times bodyweight, before and after total labrum resection. The fluid pressure within the acetabular was measured. Following labrum resection, the initial consolidation rate was 22% greater (p=0.02) and the final consolidation displacement was 21% greater (p=0.02). There was no significant difference in the final consolidation rate. Loading type (constant vs. cyclic) had no significant effect on the measured consolidation behaviour. Fluid pressurisation was observed in three of the six hips. The average pressures measured were: for constant loading, 541±61 kPa in the intact joint and 216±165 kPa following labrum resection, for cyclic loading, 550±56 kPa in the intact joint and 195±145 kPa following labrum resection. The trends observed in this experiment support the predictions of previous finite element analyses. Hydrostatic fluid pressurisation within the intra-articular space is greater with the labrum than without, which may enhance joint lubrication. Cartilage consolidation is quicker without the labrum than with, as the labrum adds an extra resistance to the flow path for interstitial fluid expression. However, both sealing mechanisms are dependent on the fit of the labrum against the femoral head.

  • early lesions of the labrum and acetabular cartilage in osteonecrosis of the femoral head
    Journal of Bone and Joint Surgery-british Volume, 2002
    Co-Authors: Peter Kloen, M Leunig, Reinhold Ganz
    Abstract:

    Osteonecrosis of the femoral head can be caused by a variety of disorders and affects the relatively young patient. Most studies have concentrated on the femoral changes; the sites of early lesions of the labrum and acetabular cartilage have not been recorded. We studied 17 hips with osteonecrosis and a wide congruent joint space on radiographs and by direct inspection of the femoral head, labrum and acetabular cartilage during surgery. All of the femoral heads had some anterosuperior flattening which reduced the head-neck ratio in this area. A consistent pattern of damage to the labrum and the acetabular cartilage was seen in all hips. Intraoperatively, impingement and the cam-effect with its spatial correlation with lesions of the labrum and acetabular cartilage were observed. These findings could be helpful when undertaking conservative surgery for osteonecrosis, since the recognition of early radiologically undetectable acetabular lesions may require modification of the surgical technique.

  • the influence of the acetabular labrum on hip joint cartilage consolidation a poroelastic finite element model
    Journal of Biomechanics, 2000
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    The goal of this study was to investigate the influence of the acetabular labrum on the consolidation, and hence the solid matrix strains and stresses, of the cartilage layers of the hip joint. A plane-strain finite element model was developed, which represented a coronal slice through the acetabular and femoral cartilage layers and the acetabular labrum. Elements with poroelastic properties were used to account for the biphasic solid/fluid nature of the cartilage and labrum. The response of the joint over an extended period of loading (10,000s) was examined to simulate the nominal compressive load that the joint is subjected to throughout the day. The model demonstrated that the labrum adds an important resistance in the flow path of the fluid being expressed from the cartilage layers of the joint. Cartilage layer consolidation was up to 40% quicker in the absence of the labrum. Following removal of the labrum from the model, the solid-on-solid contact stresses between the femoral and acetabular cartilage layers were greatly increased (up to 92% higher), which would increase the friction between the joint surfaces. In the absence of the labrum, the centre of contact shifted towards the acetabular rim. Subsurface strains and stresses were much higher without the labrum, which could contribute to fatigue damage of the cartilage layers. Finally, the labrum provided some structural resistance to lateral motion of the femoral head within the acetabulum, enhancing joint stability and preserving joint congruity.

  • the influence of the acetabular labrum on hip joint cartilage consolidation a poroelastic finite element model
    Journal of Biomechanics, 2000
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    The goal of this study was to investigate the in#uence of the acetabular labrum on the consolidation, and hence the solid matrix strains and stresses, of the cartilage layers of the hip joint. A plane-strain "nite element model was developed, which represented a coronal slice through the acetabular and femoral cartilage layers and the acetabular labrum. Elements with poroelastic properties were used to account for the biphasic solid/#uid nature of the cartilage and labrum. The response of the joint over an extended period of loading (10,000 s) was examined to simulate the nominal compressive load that the joint is subjected to throughout the day. The model demonstrated that the labrum adds an important resistance in the #ow path of the #uid being expressed from the cartilage layers of the joint. Cartilage layer consolidation was up to 40% quicker in the absence of the labrum. Following removal of the labrum from the model, the solid-on-solid contact stresses between the femoral and acetabular cartilage layers were greatly increased (up to 92% higher), which would increase the friction between the joint surfaces. In the absence of the labrum, the centre of contact shifted towards the acetabular rim. Subsurface strains and stresses were much higher without the labrum, which could contribute to fatigue damage of the cartilage layers. Finally, the labrum provided some structural resistance to lateral motion of the femoral head within the acetabulum, enhancing joint stability and preserving joint congruity. ( 2000 Elsevier Science Ltd. All rights reserved.

Peng Zhong - One of the best experts on this subject based on the ideXlab platform.

Stephen J Ferguson - One of the best experts on this subject based on the ideXlab platform.

  • an in vitro investigation of the acetabular labral seal in hip joint mechanics
    Journal of Biomechanics, 2003
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    Labrum pathology may contribute to early joint degeneration through the alteration of load transfer between, and the stresses within, the cartilage layers of the hip. We hypothesize that the labrum seals the hip joint, creating a hydrostatic fluid pressure in the intra-articular space, and limiting the rate of cartilage layer consolidation. The overall cartilage creep consolidation of six human hip joints was measured during the application of a constant load of 0.75 times bodyweight, or a cyclic sinusoidal load of 0.75±0.25 times bodyweight, before and after total labrum resection. The fluid pressure within the acetabular was measured. Following labrum resection, the initial consolidation rate was 22% greater (p=0.02) and the final consolidation displacement was 21% greater (p=0.02). There was no significant difference in the final consolidation rate. Loading type (constant vs. cyclic) had no significant effect on the measured consolidation behaviour. Fluid pressurisation was observed in three of the six hips. The average pressures measured were: for constant loading, 541±61 kPa in the intact joint and 216±165 kPa following labrum resection, for cyclic loading, 550±56 kPa in the intact joint and 195±145 kPa following labrum resection. The trends observed in this experiment support the predictions of previous finite element analyses. Hydrostatic fluid pressurisation within the intra-articular space is greater with the labrum than without, which may enhance joint lubrication. Cartilage consolidation is quicker without the labrum than with, as the labrum adds an extra resistance to the flow path for interstitial fluid expression. However, both sealing mechanisms are dependent on the fit of the labrum against the femoral head.

  • the influence of the acetabular labrum on hip joint cartilage consolidation a poroelastic finite element model
    Journal of Biomechanics, 2000
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    The goal of this study was to investigate the influence of the acetabular labrum on the consolidation, and hence the solid matrix strains and stresses, of the cartilage layers of the hip joint. A plane-strain finite element model was developed, which represented a coronal slice through the acetabular and femoral cartilage layers and the acetabular labrum. Elements with poroelastic properties were used to account for the biphasic solid/fluid nature of the cartilage and labrum. The response of the joint over an extended period of loading (10,000s) was examined to simulate the nominal compressive load that the joint is subjected to throughout the day. The model demonstrated that the labrum adds an important resistance in the flow path of the fluid being expressed from the cartilage layers of the joint. Cartilage layer consolidation was up to 40% quicker in the absence of the labrum. Following removal of the labrum from the model, the solid-on-solid contact stresses between the femoral and acetabular cartilage layers were greatly increased (up to 92% higher), which would increase the friction between the joint surfaces. In the absence of the labrum, the centre of contact shifted towards the acetabular rim. Subsurface strains and stresses were much higher without the labrum, which could contribute to fatigue damage of the cartilage layers. Finally, the labrum provided some structural resistance to lateral motion of the femoral head within the acetabulum, enhancing joint stability and preserving joint congruity.

  • the influence of the acetabular labrum on hip joint cartilage consolidation a poroelastic finite element model
    Journal of Biomechanics, 2000
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    The goal of this study was to investigate the in#uence of the acetabular labrum on the consolidation, and hence the solid matrix strains and stresses, of the cartilage layers of the hip joint. A plane-strain "nite element model was developed, which represented a coronal slice through the acetabular and femoral cartilage layers and the acetabular labrum. Elements with poroelastic properties were used to account for the biphasic solid/#uid nature of the cartilage and labrum. The response of the joint over an extended period of loading (10,000 s) was examined to simulate the nominal compressive load that the joint is subjected to throughout the day. The model demonstrated that the labrum adds an important resistance in the #ow path of the #uid being expressed from the cartilage layers of the joint. Cartilage layer consolidation was up to 40% quicker in the absence of the labrum. Following removal of the labrum from the model, the solid-on-solid contact stresses between the femoral and acetabular cartilage layers were greatly increased (up to 92% higher), which would increase the friction between the joint surfaces. In the absence of the labrum, the centre of contact shifted towards the acetabular rim. Subsurface strains and stresses were much higher without the labrum, which could contribute to fatigue damage of the cartilage layers. Finally, the labrum provided some structural resistance to lateral motion of the femoral head within the acetabulum, enhancing joint stability and preserving joint congruity. ( 2000 Elsevier Science Ltd. All rights reserved.

  • the acetabular labrum seal a poroelastic finite element model
    Clinical Biomechanics, 2000
    Co-Authors: Stephen J Ferguson, Reinhold Ganz, J T Bryant, Keita Ito
    Abstract:

    Objective. The aim of the study is to investigate the labrum’s ability to seal a pressurised layer of synovial fluid within the joint, and to study the influence of this sealing mechanism on cartilage deformation, interstitial fluid pressure and collagen solid matrix stresses. Background. Cartilage degeneration has been observed in conjunction with labrum pathology. However, little is known about the function of the labrum. Experimental observations have been reported which are consistent with a sealing function of the labrum. Methods. The model was an axisymmetric geometric approximation of the acetabular and femoral cartilage layers and the surrounding labrum. A poroelastic formulation was used to account for the solid and fluid components of these hydrated tissues. A sensitivity analysis of the labrum material properties was carried out. Results. With a compressive load of 1200 N applied across the joint model, the labrum could seal a layer of pressurised fluid between the femur and acetabulum, thus preventing contact of the articulating surfaces. With this sealing effect, loads were transferred across the joint predominantly by uniform pressurisation of the interstitial fluid of the cartilage layers. In the absence of this sealing, strains within the solid matrix of the cartilage layers were higher (e.g. 20% vs. 3%). Conclusions. The labrum can seal against fluid expression from the joint space. This sealing function protects the cartilage layers of the hip. Relevance Current treatments for labrum damage and early arthrosis may compromise the sealing function of the labrum. With continued study of the function and importance of the labrum, new surgical repair strategies can be developed to maintain the overall function of the hip joint.

Li Li-zhen - One of the best experts on this subject based on the ideXlab platform.