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Jan Deprest - One of the best experts on this subject based on the ideXlab platform.
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subsequent fertility pregnancy and gynecologic outcomes after fetoscopic Laser Therapy for twin twin transfusion syndrome compared with normal monochorionic twin gestations
American Journal of Obstetrics and Gynecology, 2018Co-Authors: Simen Vergote, Liesbeth Lewi, Willem Gheysen, Luc De Catte, Roland Devlieger, Jan DeprestAbstract:Background An improved survival and quality of life for neonatal survivors after fetoscopic Laser Therapy for twin-twin transfusion syndrome has been reported. However, little is known about the medium-term maternal effects after fetoscopic Laser Therapy with respect to reproductive and gynecologic outcomes. Objective The objective of this study was to document reproductive, obstetric, gynecological, and psychological outcomes in women who underwent fetoscopic Laser Therapy for twin-twin transfusion syndrome. Study Design This was a monocentric controlled study on consecutive women who underwent fetoscopic Laser Therapy for twin-twin transfusion syndrome between 2007 and 2013 at the University Hospitals Leuven (cases; n = 198). Controls were women followed up during the same time period for an uncomplicated monochorionic diamniotic twin pregnancy and with an uneventful course (controls; n = 211). All patients received a questionnaire inquiring on their fertility, later pregnancies, and gynecological outcomes. Results The response rate was 50.4% (cases: n = 95; controls: n = 109). Most baseline characteristics were similar across both groups. Women in the fetoscopic Laser Therapy group attempted a new pregnancy more frequently (34% [31 of 92] vs 21% [22 of 107] in controls; P Conclusion No adverse medium-term maternal effects with respect to fertility, obstetric, and gynecological outcomes were observed after fetoscopic Laser Therapy. However, these women reported more psychological or emotional problems than women with monochorionic diamniotic who did not have Laser Therapy, in particular when this was complicated by a fetal loss.
Bernard Choi - One of the best experts on this subject based on the ideXlab platform.
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blood flow dynamics after Laser Therapy of port wine stain birthmarks
Lasers in Surgery and Medicine, 2009Co-Authors: Yuchih Huang, Nadia Tran, Victor E Ross, Peter R Shumaker, Stuart J Nelson, Kristen M Kelly, Bernard ChoiAbstract:Background and Objective: During Laser Therapy of port wine stain (PWS) birthmarks, regions of perfusion may persist. We hypothesize that such regions are not readily observable even when Laser surgery is performed by highly experienced clinicians. The objective of this study was to use objective feedback to assess the acute vascular response to Laser Therapy. Study Design/Materials and Methods: A clinic-friendly Laser speckle imaging (LSI) instrument was developed to provide the clinician with real-time images of blood flow during Laser Therapy. Images were acquired from patients undergoing Laser Therapy of PWS birthmarks at Scripps Clinic and the Beckman Laser Institute and Medical Clinic. Blood flow maps were extracted from the acquired imaging data. Histogram-based analysis was applied in grading the degree of heterogeneity present in the blood flow maps after Laser Therapy. Results: Collectively, two types of patient responses were observed in response to Laser exposure: (1) an immediate increase in perfusion within minutes after Laser Therapy; and (2) an overall decrease in blood perfusion � 1 hour after Laser Therapy, with distinct regions of persistent perfusion apparent in the majority of post-treatment blood-flow images. A comparison of blood flow in PWS and adjacent normal skin demonstrated that PWS blood flow can be greater than, or sometimes equivalent to, that of normal skin. Conclusion: In general, a decrease in skin perfusion is observed during pulsed Laser Therapy of PWS birthmarks. However, a heterogeneous perfusion map was frequently observed. These regions of persistent perfusion may be due to incomplete photocoagulation of the targeted vessels. We hypothesize that immediate retreatment of these regions identified with LSI, will result in enhanced removal of the PWS vasculature. Lasers Surg. Med. 41:563–571, 2009. 2009 Wiley-Liss, Inc.
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blood flow dynamics after Laser Therapy of port wine stain birthmarks
Progress in biomedical optics and imaging, 2009Co-Authors: Yuchih Huang, Nadia Tran, Victor E Ross, Peter R Shumaker, Stuart J Nelson, Kristen M Kelly, Bernard ChoiAbstract:During Laser Therapy of port wine stain (PWS) birthmarks, regions of persistent perfusion may exist. We hypothesize that such regions, which are not readily visible, exist even during Laser surgery performed by highly experienced clinicians. The objective of this study was to use objective feedback to assess the acute vascular response to Laser Therapy. We have developed a clinic-friendly Laser speckle imaging (LSI) instrument to provide the clinician with real-time images of blood flow during Laser Therapy. We acquired images from patients undergoing Laser Therapy of PWS birthmarks at Scripps Clinic and Beckman Laser Institute and Medical Clinic. We extracted blood flow maps from the acquired imaging data. Collectively, we have observed two regimes of patient response to Therapy: 1) an immediate increase in perfusion within minutes after Laser Therapy; and 2) an overall decrease in blood perfusion approximately one hour after Laser Therapy, with distinct regions of persistent perfusion apparent in the majority of post-treatment blood-flow images. A comparison of blood flow in PWS and adjacent normal skin demonstrated that PWS blood flow can be greater than or sometimes equivalent to that of normal skin. Regions of persistent perfusion frequently exist immediately after Laser Therapy of PWS birthmarks. Existence of these regions may be correlated to the need for multiple treatment sessions to improve substantially PWS skin appearance. With the use of intraoperative LSI, immediate retreatment of these regions may improve the outcome of each session.
Ameen Abdullah Yahya Alakwa - One of the best experts on this subject based on the ideXlab platform.
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efficacy of low level Laser Therapy in the treatment of burning mouth syndrome a systematic review
Photodiagnosis and Photodynamic Therapy, 2017Co-Authors: Sadeq Ali Almaweri, Fawad Javed, Butchibabu Kalakonda, Nader Ahmed Alaizari, Walid A Alsoneidar, Ameen Abdullah Yahya AlakwaAbstract:Abstract Background Burning mouth syndrome (BMS) is a chronic pain condition with indefinite cure, predominantly affecting post-menopausal women. The aim of this study was to systematically review the efficacy of low level Laser Therapy in the treatment of burning mouth syndrome (BMS). Methods PubMed, Embase and Scopus were searched from date of inception till and including October 2016 using various combinations of the following keywords: burning mouth syndrome, BMS, stomatodynia, Laser Therapy, Laser treatment and photoTherapy. The inclusion criteria were: Prospective, retrospective and case series studies. Letter to editors, reviews, experimental studies, studies that were not published in English, theses, monographs, and abstracts presented in scientific events were excluded. Due to heterogeneity of data no statistical analyses were performed. Results Ten clinical studies fulfilled the eligibility criteria, five of which were randomized clinical trials. In these studies, the Laser wavelengths, power output and duration of irradiation ranged between 630–980 nm, 20–300 mW, 10 s–15 min, respectively. Most of studies reported Laser to be an effective Therapy strategy for management of BMS. Conclusion Majority of the studies showed that Laser Therapy seemed to be effective in reducing pain in BMS patients. However, due to the varied methodologies and substantial variations in Laser parameters among these studies, more clinical trials are required to ascertain the efficacy of Laser for treating BMS.
Mona Mahmoudbeyk - One of the best experts on this subject based on the ideXlab platform.
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a comparative study of the efficacy of fractional neodymium doped yttrium aluminum garnet nd yag Laser Therapy alone and in combination with erbium yag Laser Therapy tracing and objective measurement of melanin index in macular amyloidosis
Lasers in Medical Science, 2020Co-Authors: Mohammad Ali Nilforoushzadeh, Sara Zolghadr, Maryam Heidarikharaji, Shiva Alavi, Mona MahmoudbeykAbstract:Macular amyloidosis (MA) is a common form of primary localized cutaneous amyloidosis, characterized by the eruption of brown pigments of the skin with a rippled pattern. MA can be of cosmetic concern for patients, and its treatment is challenging. In this study, we aimed to find new effective approaches for MA treatment. A total of 39 patients with the clinical diagnosis of MA were treated with two types of Laser Therapy, and the effectiveness of each approach was examined. Fractional Q-switched 10.64 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) Laser Therapy was compared with a combination of fractional Q-switched 10.64 nm Nd:YAG Laser and long-pulsed fractional erbium:YAG Laser Therapy. Melanin biometric measurements were performed using a Mexameter, objective image-based evaluation was carried out, and the itching score and patient satisfaction were examined. Mexameter-based analysis showed that both types of Laser Therapy were effective in the treatment of MA, causing a significant decrease in the amount of melanin in the treated areas (P < 0.05). Also, combination of two types of Laser Therapy was significantly more effective than one type alone (P < 0.05). The itching score significantly decreased in patients undergoing a combination of Laser therapies. Also, a positive correlation was observed between the amount of melanin and degree of itching in the treated areas. Moreover, analysis of patient satisfaction showed that more than 90% of patients had excellent satisfaction with combination Laser Therapy. The results confirmed the significant positive effects of both fractional Nd:YAG Laser alone and in combination with fractional erbium:YAG Laser Therapy considering the reduction in melanin content; however, combination of two types of Laser Therapy was more effective than one type alone. Trial registration: IRCT20080901001159N23
Bahram Sarkarati - One of the best experts on this subject based on the ideXlab platform.
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Effect of low-level Laser Therapy (LLLT) on orthodontic tooth movement
Lasers in Medical Science, 2013Co-Authors: Ghizlane Genc, İlken Kocadereli, Ferda Tasar, Kamer Kilinc, Bahram SarkaratiAbstract:The aim of this study is to evaluate the effects of low-level Laser Therapy (LLLT) on (1) the velocity of orthodontic tooth movement and (2) the nitric oxide levels in gingival crevicular fluid (GCF) during orthodontic treatment. The sample consisted of 20 patients (14 girls, six boys) whose maxillary first premolars were extracted and canines distalized. A gallium-aluminum-arsenide (Ga-Al-As) diode Laser was applied on the day 0, and the 3rd, 7th, 14th, 21st, and 28th days when the retraction of the maxillary lateral incisors was initiated. The right maxillary lateral incisors composed the study group (the Laser group), whereas the left maxillary lateral incisors served as the control. The teeth in the Laser group received a total of ten doses of Laser application: five doses from the buccal and five doses from the palatal side (two cervical, one middle, two apical) with an output power of 20 mW and a dose of 0.71 J /cm^2. Gingival crevicular fluid samples were obtained on the above-mentioned days, and the nitric oxide levels were analyzed. Bonferroni and repeated measures variant analysis tests were used for statistical analysis with the significance level set at p ≤ 0.05. The application of low-level Laser Therapy accelerated orthodontic tooth movement significantly; there were no statistically significant changes in the nitric oxide levels of the gingival crevicular fluid during orthodontic treatment.