The Experts below are selected from a list of 20796 Experts worldwide ranked by ideXlab platform
Vishal Jhanji - One of the best experts on this subject based on the ideXlab platform.
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vector analysis of astigmatic correction after small incision lenticule extraction and femtosecond assisted LASIK for low to moderate myopic astigmatism
British Journal of Ophthalmology, 2016Co-Authors: Tommy C Y Chan, Alex L K Ng, George P M Cheng, Zheng Wang, Cong Ye, Clement C Y Tham, Vishal JhanjiAbstract:Aim To compare astigmatic correction between femtosecond-assisted laser in situ keratomileusis (LASIK) and small-incision lenticule extraction (SMILE). Methods A total of 111 patients were included in this prospective study. Fifty-seven eyes were treated with LASIK and 54 eyes were treated with SMILE for myopia with low to moderate (−0.25 to −4.0 D) astigmatism. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity and manifest refraction were measured preoperatively and at 1 and 3 months postoperatively. Visual and refractive outcomes were reported. Changes in refractive astigmatism were evaluated using vector analysis. Results Preoperative characteristics were similar between both groups. The UDVA at 1 and 3 months was better in the LASIK group compared with the SMILE group (p 0.596) between the two groups. Surgically induced astigmatism was significantly lower in the SMILE group (p 0.122). Conclusions Our results showed that SMILE offered a less favourable astigmatic correction comparable to femtosecond-assisted LASIK in eyes with low to moderate myopic astigmatism. The alignment of treatment was more variable in SMILE, leading to a lower efficacy compared with LASIK by 3 months postoperatively.
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randomized double masked controlled trial comparing pain scores with and without the use of supplementary 2 lidocaine gel in LASIK
American Journal of Ophthalmology, 2012Co-Authors: Anita S Y Ng, Vishal JhanjiAbstract:Purpose To compare pain scores with and without supplementary topical 2% lidocaine gel in patients undergoing simultaneous bilateral laser-assisted in situ keratomileusis (LASIK) under topical anesthesia using 0.5% proparacaine eye drops. Design Randomized double-masked placebo-controlled trial. Methods Fifty-one Chinese subjects (102 eyes, with 51 eyes in each arm) were included. One eye was randomly allocated to have supplementary 2% lidocaine gel while the other eye received carbomer gel as control, in addition to topical 0.5% proparacaine. The pain scores for each eye during microkeratome flap creation, during laser ablation, and at 15, 30, and 45 minutes after LASIK were assessed. An overall pain score of the LASIK procedure was also obtained. Primary outcome measures were pain scores during and after LASIK. Secondary outcomes included need for additional topical anesthesia, patient cooperation score, and duration and complications of surgery. Results In the 2% lidocaine gel–treated group, the pain scores were significantly lower during microkeratome flap creation and laser ablation, and postoperatively at 30 and 45 minutes ( P P = .0004) and were more cooperative ( P = .019) as compared to the carbomer gel group. No surgical or postoperative complications were observed. Conclusions The use of supplementary 2% lidocaine gel in LASIK is effective in lowering the pain experienced during and up to 45 minutes after LASIK.
Yan Wang - One of the best experts on this subject based on the ideXlab platform.
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comparison of corneal sensitivity between fs LASIK and femtosecond lenticule extraction relex flex or small incision lenticule extraction relex smile for myopic eyes
Graefes Archive for Clinical and Experimental Ophthalmology, 2013Co-Authors: Yan WangAbstract:Background To compare the effect on corneal sensitivity between femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and femtosecond lenticule extraction (ReLEx flex) or FS-LASIK and small-incision lenticule extraction (ReLEx smile) surgery.
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Comparison of higher-order aberration and optical quality after Epi-LASIK and LASIK for myopia.
Graefes Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: Xiaoyan Yang, Yan Wang, Kanxing Zhao, Lihua FangAbstract:Background Epipolis laser in keratomileusis (Epi-LASIK) and laser in situ keratomileusis (LASIK) are two main surgical techniques for myopia in refractive surgery at present. However, the visual outcome and optical quality after the two procedures are not clear. We conducted the current prospective study to compare ocular higher-order aberrations and evaluate optical quality after Epi-LASIK and LASIK.
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The Shape of Posterior Corneal Surface in Normal, Post-LASIK, and Post- epi-LASIK Eyes
Investigative Ophthalmology & Visual Science, 2010Co-Authors: Lin Zhang, Yan WangAbstract:RESULTS. In normal eyes, the heights were lower in the vertical meridian than in the horizontal meridian and were also lower in the superior hemisphere than in the inferior hemisphere. In post-LASIK eyes, almost all regions protruded 1 month after surgery, except for the 6-mm diameter, which exhibited a slight but not significant (P 0.731) backward displacement. The various elevations returned to original levels 6 months after LASIK. In the post‐epi-LASIK group, there was a significant backward displacement in the center and 2-mm regions after surgery. Moreover, there was no shift at the 4-mm diameter, and the 6-mm diameter showed a progressive forward shift. CONCLUSIONS. The shape of the normal posterior corneal surface exhibited obvious regional disparities and radial asymmetry. The displacement after LASIK was observed as time-dependent changes that protruded at an early stage but then returned to original levels 6 months after surgery. On the other hand, the displacement after epi-LASIK appeared as region-dependent changes that could be divided into central and peripheral parts that displayed backward and forward shift trends, respectively. (Invest Ophthalmol Vis Sci. 2010;51:3468‐3475) DOI:10.1167/ iovs.09-4811
Tommy C Y Chan - One of the best experts on this subject based on the ideXlab platform.
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vector analysis of astigmatic correction after small incision lenticule extraction and femtosecond assisted LASIK for low to moderate myopic astigmatism
British Journal of Ophthalmology, 2016Co-Authors: Tommy C Y Chan, Alex L K Ng, George P M Cheng, Zheng Wang, Cong Ye, Clement C Y Tham, Vishal JhanjiAbstract:Aim To compare astigmatic correction between femtosecond-assisted laser in situ keratomileusis (LASIK) and small-incision lenticule extraction (SMILE). Methods A total of 111 patients were included in this prospective study. Fifty-seven eyes were treated with LASIK and 54 eyes were treated with SMILE for myopia with low to moderate (−0.25 to −4.0 D) astigmatism. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity and manifest refraction were measured preoperatively and at 1 and 3 months postoperatively. Visual and refractive outcomes were reported. Changes in refractive astigmatism were evaluated using vector analysis. Results Preoperative characteristics were similar between both groups. The UDVA at 1 and 3 months was better in the LASIK group compared with the SMILE group (p 0.596) between the two groups. Surgically induced astigmatism was significantly lower in the SMILE group (p 0.122). Conclusions Our results showed that SMILE offered a less favourable astigmatic correction comparable to femtosecond-assisted LASIK in eyes with low to moderate myopic astigmatism. The alignment of treatment was more variable in SMILE, leading to a lower efficacy compared with LASIK by 3 months postoperatively.
Yile Chen - One of the best experts on this subject based on the ideXlab platform.
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clinical outcomes after smile and femtosecond laser assisted LASIK for myopia and myopic astigmatism a prospective randomized comparative study
Cornea, 2016Co-Authors: Yile Chen, Danyang Wang, Xiaoying Zhang, Yugui Zhou, Jiexu He, Ting ZhangAbstract:Purpose:To compare the clinical outcomes of small-incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK (FS-LASIK) for the correction of myopia and myopic astigmatism.Methods:In this prospective, randomized, comparative study, SMILE surgery was performed in 113 eyes with a mean
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differences in the corneal biomechanical changes after smile and LASIK
Journal of Refractive Surgery, 2014Co-Authors: Danyang Wang, Yile Chen, Xiaoying Zhang, Yangtao Xu, Jianchao Wang, Chiho ToAbstract:Abstract To compare the corneal biomechanical properties before and after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK in different levels of myopia with the Ocular Response Analyzer (Reichert Ophthalmic Instruments, Depew, NY). A total of 187 and 79 eyes that received SMILE or LASIK, respectively, between January and June 2013 at Zhongshan Ophthalmic Center were enrolled in this study. Patients were grouped according to surgery type (SMILE or LASIK) and -6.00 diopters (D) or less (> -6.00 D) or myopia greater than -6.00 D (>-6.00 D). Corneal hysteresis, corneal resistance factor, and 37 waveform parameters were recorded and compared preoperatively and at 1 week and 1 and 3 months postoperatively. There was a significant decrease of corneal hysteresis, corneal resistance factor, p1area, and p2area, and an increase of path1 and path2 in both SMILE and LASIK. In myopia -6.00 D or less, the differences between SMILE and LASIK were not significant (P > .05), but in myopia greater than -6.00 D, the corneal hysteresis, corneal resistance factor, p1area, and p2area decreased significantly more in LASIK than in SMILE (P
Jorge L Alio - One of the best experts on this subject based on the ideXlab platform.
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ten years after photorefractive keratectomy prk and laser in situ keratomileusis LASIK for moderate to high myopia control matched study
British Journal of Ophthalmology, 2009Co-Authors: Jorge L Alio, Dolores Ortiz, Orkun Muftuoglu, Maria Jose GarciaAbstract:Objective : To compare the long-term outcomes of PRK and LASIK for myopia between -6 and -10 D. Methods : A retrospective, control-matched study including 68 eyes, 34 who underwent PRK and 34 LASIK, with myopia between -6 and -10 D, operated using the VISX 20/20 excimer laser was performed. Optical zones of 5.5 to 6 mm were used. All PRK-treated eyes were matched with LASIK-treated eyes having same age, spherical equivalent within ± 1.25 D, sphere within ± 1.5 D, and cylinder within ± 2.5 D. All patients were evaluated 3 months, 1 year, 2 years, 5 years, and 10 years after surgery. The main outcomes measures were refractive predictability and stability, safety, efficacy, retreatment rate. Results : At ten years, 20 (71%) and 23 (88%) were within ± 1.00 D after PRK and LASIK respectively. The retreatment rate was 35% and 18% respectively. No eye lost more than 2 lines of BSCVA in both groups. The efficacy was 0.90 for PRK and 0.95 for LASIK. Conclusions : Both PRK and LASIK were safe for moderate myopia. LASIK demonstrated slightly better efficacy, predictability, and less rate of retreatment after 10 years. The technical improvements should be taken into account where compare these results with those obtained more recently.
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femtosecond laser versus mechanical keratome LASIK for myopia
Ophthalmology, 2007Co-Authors: Robert Montesmico, Antonio Rodriguezgalietero, Jorge L AlioAbstract:Objective To assess efficacy, safety, predictability, stability, and changes in corneal higher-order aberrations (CHOAs) and contrast sensitivity (CS) after a femtosecond laser for LASIK and standard LASIK for myopia. Design Prospective, randomized, comparative clinical study. Participants Two hundred eyes of 100 consecutive patients who underwent LASIK treatment using the VISX S2 laser system. A femtosecond laser for flap creation was used in 100 eyes (50 patients; spherical equivalent [SE], −2.85±1.79 diopters [D]), and a mechanical microkeratome was used in 100 eyes (50 patients; SE, −2.90±1.63 D). Methods Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refraction, CS by means of the Functional Acuity Contrast Test, and CHOAs by means of custom software linked to topography were evaluated preoperatively and 6 months after treatment. Main Outcome Measures Efficacy, safety, predictability, stability, CHOAs, and CS were evaluated before and after surgery at 6 months' follow-up. Results At 6 months postoperatively, UCVA was 1.0 or better in 100% of the eyes. Efficacy indexes were 1.07 for the femtosecond laser for LASIK patients and 1.00 for LASIK patients. No eye lost ≥1 lines of BCVA; for the femtosecond laser for LASIK group, 24 eyes gained 1 line, and 18 eyes gained ≥2 lines; for the LASIK group, 18 eyes gained 1 line. The femtosecond laser for LASIK group showed a percentage of eyes (98%) within the 0.5-D range in SE higher than that of the LASIK group (92%). For a 3.5-mm pupil, CHOAs' root-mean-square (RMS) increased for both the femtosecond laser for LASIK (2.21-fold) and LASIK (2.81-fold) groups. For a 6-mm pupil, CHOA RMSs were increased significantly after femtosecond laser for LASIK (4.18-fold) and LASIK (5.07-fold) surgeries ( P P Conclusions A femtosecond laser for LASIK surgery is an effective and, in this series, safe procedure for treatment of myopia. The improvements in UCVA and CS after the femtosecond laser for LASIK are related to the differences in postoperative CHOAs found with femtosecond and microkeratome flap creation.
