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E Ogbonna - One of the best experts on this subject based on the ideXlab platform.
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histochemical assessment of moringa oleifera oil and walnut oil on cadmium induced Lateral Geniculate Body damage in developing male wistar rats rattus novergiccus
Anatomy journal of Africa, 2019Co-Authors: O D Omotoso, S A Adelakun, E Ogbonna, B P Akwu, I J IdomehAbstract:The brain is vulnerable to oxidative damage due to its high oxygen consumption. This Study investigate the effects of cadmium on the Lateral Geniculate Body of developing male wistar rats and ameliorative potential of Moringa oleifera seed oil and walnut oil extracts. Seven groups of five animals each were used in this experiment. Group A received 3ml of 0.9% normal saline; group B received 2.5mg/kg bw of 3CdSO 4 .8H 2 O, group C received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E, group D received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E + 2.5mg/kg bw Cd, group E received 2.5mg/kg bw Cd + 4mg/kg bw Moringa oleifera oil, group F received 2.5mg/kg bw Cd + 4mg/kg bw walnut oil, while group G received 2.5mg/kg bw Cd + 2mg/kg bw walnut + 2mg/kg bw Moringa oleifera oil concomitantly for 3weeks. Parameter tested includes LDH, G6PD in brain tissues, SOD and GPx enzymes in brain homogenates and serum and cresyl fast violet stain in the brain tissues. Cd administration significantly increased SOD, GPx, LDH and decreased G6PD level in brain tissue and decreased their activity in serum when compared with Group A control rats. There was marked reduction and lost in the distribution of nissl substances of the studied tissues of Cd administered animals. However, administration of vitamin C & E, walnut and Moringa oleifera oil restored damaged tissues. Walnut and Moringa oleifera seed oil therefore attenuated the oxidative damage and morphological changes induced by cadmium in the Lateral Geniculate Body of the brain of the young male wistar rats. Key Words : Lateral Geniculate Body, Antioxidant, Histochemical, Cadmium, Oxidative Damage
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histomorphological characterization of moringa oleifera oil and walnut oil on cadmium induced Lateral Geniculate Body damage in adult wistar rats rattus novergiccus
Journal of Biology and Medicine, 2019Co-Authors: O D Omotoso, S A Adelakun, I J Idomeh, E OgbonnaAbstract:Background: Cadmium (Cd) has been reported to cause distinct neurotoxic effects in adult and newborn animals. This study was designed to investigate some of the effects caused by cadmium on the Lateral Geniculate Body of adult male wistar rats and the ameliorative properties of antioxidants present in Moringa oleifera seed oil and walnut oil extracts.
O D Omotoso - One of the best experts on this subject based on the ideXlab platform.
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histochemical assessment of moringa oleifera oil and walnut oil on cadmium induced Lateral Geniculate Body damage in developing male wistar rats rattus novergiccus
Anatomy journal of Africa, 2019Co-Authors: O D Omotoso, S A Adelakun, E Ogbonna, B P Akwu, I J IdomehAbstract:The brain is vulnerable to oxidative damage due to its high oxygen consumption. This Study investigate the effects of cadmium on the Lateral Geniculate Body of developing male wistar rats and ameliorative potential of Moringa oleifera seed oil and walnut oil extracts. Seven groups of five animals each were used in this experiment. Group A received 3ml of 0.9% normal saline; group B received 2.5mg/kg bw of 3CdSO 4 .8H 2 O, group C received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E, group D received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E + 2.5mg/kg bw Cd, group E received 2.5mg/kg bw Cd + 4mg/kg bw Moringa oleifera oil, group F received 2.5mg/kg bw Cd + 4mg/kg bw walnut oil, while group G received 2.5mg/kg bw Cd + 2mg/kg bw walnut + 2mg/kg bw Moringa oleifera oil concomitantly for 3weeks. Parameter tested includes LDH, G6PD in brain tissues, SOD and GPx enzymes in brain homogenates and serum and cresyl fast violet stain in the brain tissues. Cd administration significantly increased SOD, GPx, LDH and decreased G6PD level in brain tissue and decreased their activity in serum when compared with Group A control rats. There was marked reduction and lost in the distribution of nissl substances of the studied tissues of Cd administered animals. However, administration of vitamin C & E, walnut and Moringa oleifera oil restored damaged tissues. Walnut and Moringa oleifera seed oil therefore attenuated the oxidative damage and morphological changes induced by cadmium in the Lateral Geniculate Body of the brain of the young male wistar rats. Key Words : Lateral Geniculate Body, Antioxidant, Histochemical, Cadmium, Oxidative Damage
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histomorphological characterization of moringa oleifera oil and walnut oil on cadmium induced Lateral Geniculate Body damage in adult wistar rats rattus novergiccus
Journal of Biology and Medicine, 2019Co-Authors: O D Omotoso, S A Adelakun, I J Idomeh, E OgbonnaAbstract:Background: Cadmium (Cd) has been reported to cause distinct neurotoxic effects in adult and newborn animals. This study was designed to investigate some of the effects caused by cadmium on the Lateral Geniculate Body of adult male wistar rats and the ameliorative properties of antioxidants present in Moringa oleifera seed oil and walnut oil extracts.
I J Idomeh - One of the best experts on this subject based on the ideXlab platform.
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histochemical assessment of moringa oleifera oil and walnut oil on cadmium induced Lateral Geniculate Body damage in developing male wistar rats rattus novergiccus
Anatomy journal of Africa, 2019Co-Authors: O D Omotoso, S A Adelakun, E Ogbonna, B P Akwu, I J IdomehAbstract:The brain is vulnerable to oxidative damage due to its high oxygen consumption. This Study investigate the effects of cadmium on the Lateral Geniculate Body of developing male wistar rats and ameliorative potential of Moringa oleifera seed oil and walnut oil extracts. Seven groups of five animals each were used in this experiment. Group A received 3ml of 0.9% normal saline; group B received 2.5mg/kg bw of 3CdSO 4 .8H 2 O, group C received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E, group D received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E + 2.5mg/kg bw Cd, group E received 2.5mg/kg bw Cd + 4mg/kg bw Moringa oleifera oil, group F received 2.5mg/kg bw Cd + 4mg/kg bw walnut oil, while group G received 2.5mg/kg bw Cd + 2mg/kg bw walnut + 2mg/kg bw Moringa oleifera oil concomitantly for 3weeks. Parameter tested includes LDH, G6PD in brain tissues, SOD and GPx enzymes in brain homogenates and serum and cresyl fast violet stain in the brain tissues. Cd administration significantly increased SOD, GPx, LDH and decreased G6PD level in brain tissue and decreased their activity in serum when compared with Group A control rats. There was marked reduction and lost in the distribution of nissl substances of the studied tissues of Cd administered animals. However, administration of vitamin C & E, walnut and Moringa oleifera oil restored damaged tissues. Walnut and Moringa oleifera seed oil therefore attenuated the oxidative damage and morphological changes induced by cadmium in the Lateral Geniculate Body of the brain of the young male wistar rats. Key Words : Lateral Geniculate Body, Antioxidant, Histochemical, Cadmium, Oxidative Damage
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histomorphological characterization of moringa oleifera oil and walnut oil on cadmium induced Lateral Geniculate Body damage in adult wistar rats rattus novergiccus
Journal of Biology and Medicine, 2019Co-Authors: O D Omotoso, S A Adelakun, I J Idomeh, E OgbonnaAbstract:Background: Cadmium (Cd) has been reported to cause distinct neurotoxic effects in adult and newborn animals. This study was designed to investigate some of the effects caused by cadmium on the Lateral Geniculate Body of adult male wistar rats and the ameliorative properties of antioxidants present in Moringa oleifera seed oil and walnut oil extracts.
S A Adelakun - One of the best experts on this subject based on the ideXlab platform.
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histochemical assessment of moringa oleifera oil and walnut oil on cadmium induced Lateral Geniculate Body damage in developing male wistar rats rattus novergiccus
Anatomy journal of Africa, 2019Co-Authors: O D Omotoso, S A Adelakun, E Ogbonna, B P Akwu, I J IdomehAbstract:The brain is vulnerable to oxidative damage due to its high oxygen consumption. This Study investigate the effects of cadmium on the Lateral Geniculate Body of developing male wistar rats and ameliorative potential of Moringa oleifera seed oil and walnut oil extracts. Seven groups of five animals each were used in this experiment. Group A received 3ml of 0.9% normal saline; group B received 2.5mg/kg bw of 3CdSO 4 .8H 2 O, group C received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E, group D received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E + 2.5mg/kg bw Cd, group E received 2.5mg/kg bw Cd + 4mg/kg bw Moringa oleifera oil, group F received 2.5mg/kg bw Cd + 4mg/kg bw walnut oil, while group G received 2.5mg/kg bw Cd + 2mg/kg bw walnut + 2mg/kg bw Moringa oleifera oil concomitantly for 3weeks. Parameter tested includes LDH, G6PD in brain tissues, SOD and GPx enzymes in brain homogenates and serum and cresyl fast violet stain in the brain tissues. Cd administration significantly increased SOD, GPx, LDH and decreased G6PD level in brain tissue and decreased their activity in serum when compared with Group A control rats. There was marked reduction and lost in the distribution of nissl substances of the studied tissues of Cd administered animals. However, administration of vitamin C & E, walnut and Moringa oleifera oil restored damaged tissues. Walnut and Moringa oleifera seed oil therefore attenuated the oxidative damage and morphological changes induced by cadmium in the Lateral Geniculate Body of the brain of the young male wistar rats. Key Words : Lateral Geniculate Body, Antioxidant, Histochemical, Cadmium, Oxidative Damage
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histomorphological characterization of moringa oleifera oil and walnut oil on cadmium induced Lateral Geniculate Body damage in adult wistar rats rattus novergiccus
Journal of Biology and Medicine, 2019Co-Authors: O D Omotoso, S A Adelakun, I J Idomeh, E OgbonnaAbstract:Background: Cadmium (Cd) has been reported to cause distinct neurotoxic effects in adult and newborn animals. This study was designed to investigate some of the effects caused by cadmium on the Lateral Geniculate Body of adult male wistar rats and the ameliorative properties of antioxidants present in Moringa oleifera seed oil and walnut oil extracts.
Alán Alpár - One of the best experts on this subject based on the ideXlab platform.
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perisynaptic aggrecan based extracellular matrix coats in the human Lateral Geniculate Body devoid of perineuronal nets
Journal of Neuroscience Research, 2012Co-Authors: Dávid Lendvai, Gert Bruckner, Markus Morawski, László Négyessy, Gabor Baksa, Tibor Glasz, Lajos Patonay, R.t. Matthews, Th. Arendt, Alán AlpárAbstract:The extracellular matrix surrounds different neuronal compartments in the mature nervous system. In a variety of vertebrates, most brain regions are loaded with a distinct type of extracellular matrix around the somatodendritic part of neurons, termed perineuronal nets. The present study reports that chondrotin sulfate proteoglycan-based matrix is structured differently in the human Lateral Geniculate Body. Using various chondrotin sulfate proteoglycan-based extracellular matrix antibodies, we show that perisomatic matrix labeling is rather weak or absent, whereas dendrites are contacted by axonal coats appearing as small, oval structures. Confocal laser scanning microscopy and electron microscopy demonstrated that these typical structures are associated with synaptic loci on dendrites. Using multiple labelings, we show that different chondrotin sulfate proteoglycan components of the extracellular matrix do not associate exclusively with neuronal structures but possibly associate with glial structures as well. Finally, we confirm and extend previous findings in primates that intensity differences of various extracellular matrix markers between magno- and parvocellular layers reflect functional segregation between these layers in the human Lateral Geniculate Body. © 2011 Wiley Periodicals, Inc.
