The Experts below are selected from a list of 9462 Experts worldwide ranked by ideXlab platform
Omidvar Rezaei - One of the best experts on this subject based on the ideXlab platform.
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biLateral choroid plexus metastasis from papillary thyroid carcinoma case report and review of the literature
World Neurosurgery, 2015Co-Authors: Guive Sharifi, Mehrdad Hosseinzadeh Bakhtevari, Mohsen Alghasi, Masood Asghsri Nosari, Ramin Rahmanzade, Omidvar RezaeiAbstract:Background Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. It has an indolent clinical course and favorable prognosis. Brain metastasis is uncommon and complicates about 0.1%–5% of PTCs. Metastasis to the choroid plexus of the Lateral Ventricles has been reported in 7 cases of thyroid malignancies, all of which were uniLateral. Methods We report a case of a 52-year-old woman with a history of PTC who presented with severe headache, nausea and vomiting, right hemiparesis, and speech disturbance. Imaging studies depicted lesions in both Lateral Ventricles. Results The patient underwent microsurgical tumor resection. Histopathologic examination revealed choroid plexus metastasis from PTC. Conclusions Metastases to the choroid plexus from extracranial tumors are very rare, with only a few cases reported thus far. A demographic analysis of these cases suggests there may be a tropism of some extracranial carcinomas, such as renal cell carcinoma, for choroid plexus, especially in the Lateral Ventricles. We report the eighth case of choroid plexus metastasis, but it is the first biLateral one arising from thyroid cancer.
Jun Konishi - One of the best experts on this subject based on the ideXlab platform.
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enlarged Lateral Ventricles inversely correlate with reduced corpus callosum central volume in first episode schizophrenia association with functional measures
Brain Imaging and Behavior, 2016Co-Authors: Sylvain Bouix, Jun Konishi, Gabriella A M Blokland, Raquelle I Mesholamgately, Jill M Goldstein, Marek Kubicki, Joanne WojcikAbstract:The Lateral and third Ventricles, as well as the corpus callosum (CC), are known to be affected in schizophrenia. Here we investigate whether abnormalities in the Lateral Ventricles (LVs), third ventricle, and corpus callosum are related to one another in first episode schizophrenia (FESZ), and whether such abnormalities show progression over time. Nineteen FESZ and 19 age- and handedness-matched controls were included in the study. MR images were acquired on a 3-Tesla MRI at baseline and ~1.2 years later. FreeSurfer v.5.3 was employed for segmentation. Two-way or univariate ANCOVAs were used for statistical analysis, where the covariate was intracranial volume. Group and gender were included as between-subjects factors. Percent volume changes between baseline and follow-up were used to determine volume changes at follow-up. BiLateral LV and third ventricle volumes were significantly increased, while central CC volume was significantly decreased in patients compared to controls at baseline and at follow-up. In FESZ, the biLateral LV volume was also inversely correlated with volume of the central CC. This inverse correlation was not present in controls. In FESZ, an inverse correlation was found between percent volume increase from baseline to follow-up for biLateral LVs and lesser improvement in the Global Assessment of Functioning score. Significant correlations were observed for abnormalities of central CC, LVs and third ventricle volumes in FESZ, suggesting a common neurodevelopmental origin in schizophrenia. Enlargement of Ventricles was associated with less improvement in global functioning over time.
Guive Sharifi - One of the best experts on this subject based on the ideXlab platform.
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biLateral choroid plexus metastasis from papillary thyroid carcinoma case report and review of the literature
World Neurosurgery, 2015Co-Authors: Guive Sharifi, Mehrdad Hosseinzadeh Bakhtevari, Mohsen Alghasi, Masood Asghsri Nosari, Ramin Rahmanzade, Omidvar RezaeiAbstract:Background Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. It has an indolent clinical course and favorable prognosis. Brain metastasis is uncommon and complicates about 0.1%–5% of PTCs. Metastasis to the choroid plexus of the Lateral Ventricles has been reported in 7 cases of thyroid malignancies, all of which were uniLateral. Methods We report a case of a 52-year-old woman with a history of PTC who presented with severe headache, nausea and vomiting, right hemiparesis, and speech disturbance. Imaging studies depicted lesions in both Lateral Ventricles. Results The patient underwent microsurgical tumor resection. Histopathologic examination revealed choroid plexus metastasis from PTC. Conclusions Metastases to the choroid plexus from extracranial tumors are very rare, with only a few cases reported thus far. A demographic analysis of these cases suggests there may be a tropism of some extracranial carcinomas, such as renal cell carcinoma, for choroid plexus, especially in the Lateral Ventricles. We report the eighth case of choroid plexus metastasis, but it is the first biLateral one arising from thyroid cancer.
Mohamed Eshra - One of the best experts on this subject based on the ideXlab platform.
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endoscopic management of third ventricular colloid cysts in mildly dilated Lateral Ventricles
Neurosurgical Review, 2019Co-Authors: Mohamed EshraAbstract:Colloid cysts of the third ventricle are considered as benign lesions. The clinical manifestations are not clear in most of cases. Many treatment options are available and endoscopic removal of the cysts proves to be a very successful method especially if the Lateral Ventricles are moderately or severely dilated. Sometimes, we faced cases with non- or mildly dilated Ventricles which may add more risks to the operation, limit the radicality of removal, or abort the procedure entirely. Sixteen cases of colloid cyst with mildly dilated Ventricles were operated upon between 2008 and 2016 using the rigid endoscopic system. Twelve were female and four were male. Their ages were between 17 and 40 years old. Headaches and epileptic fits were the presenting symptoms in 13 cases and 2 cases respectively. One case was asymptomatic. The patients were followed up from 1 to 4 years. Total removal in 12 cases and evacuation of the contents and partial removal in 4 cases. Mild transient complications occurred in the form of fever in seven cases, vomiting in four cases or short-term recent memory loss in three cases. No deaths occurred due to the procedures. Working endoscopically in enlarged Ventricles is very effective and easy; however, small sized Ventricles do not prevent safe and effective complete removal of colloid cysts. Cases with residual cyst wall do not suffer from recurrence.
Joanne Wojcik - One of the best experts on this subject based on the ideXlab platform.
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diffusion abnormalities in the corpus callosum in first episode schizophrenia associated with enlarged Lateral Ventricles and symptomatology
Psychiatry Research-neuroimaging, 2019Co-Authors: Sylvain Bouix, Gabriella A M Blokland, Raquelle I Mesholamgately, Marek Kubicki, Joanne Wojcik, Jennifer Fitzsimmons, Zora Kikinis, Tracey L Petryshen, Ofer PasternakAbstract:Abstract Introduction Abnormalities in the corpus callosum (CC) and the Lateral Ventricles (LV) are hallmark features of schizophrenia. These abnormalities have been reported in chronic and in first episode schizophrenia (FESZ). Here we explore further associations between CC and LV in FESZ using diffusion tensor imaging (DTI). Methods . Sixteen FESZ patients and 16 healthy controls (HC), matched on age, gender, and handedness participated in the study. Diffusion and structural imaging scans were acquired on a 3T GE Signa magnet. Volumetric measures for LV and DTI measures for five CC subdivisions were completed in both groups. In addition, two-tensor tractography, the latter corrected for free-water (FAt), was completed for CC. Correlations between LV and DTI measures of the CC were examined in both groups, while correlations between DTI and clinical measures were examined in only FESZ. Results Results from two-tensor tractography demonstrated decreased FAt and increased trace and radial diffusivity (RDt) in the five CC subdivisions in FESZ compared to HC. Central CC diffusion measures in FESZ were significantly correlated with volume of the LV, i.e., decreased FAt values were associated with larger LV volume, while increased RDt and trace values were associated with larger LV volume. In controls, correlations were also significant, but they were in the opposite direction from FESZ. In addition, decreased FAt in FESZ was associated with more positive symptoms. Discussion Partial volume corrected FAt, RDt, and trace abnormalities in the CC in FESZ suggest possible de- or dys-myelination, or changes in axonal diameters, all compatible with neurodevelopmental theories of schizophrenia. Correlational findings between the volume of LV and diffusion measures in FESZ reinforce the concept of a link between abnormalities in the LV and CC in early stages of schizophrenia and are also compatible with neurodevelopmental abnormalities in this population.
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enlarged Lateral Ventricles inversely correlate with reduced corpus callosum central volume in first episode schizophrenia association with functional measures
Brain Imaging and Behavior, 2016Co-Authors: Sylvain Bouix, Jun Konishi, Gabriella A M Blokland, Raquelle I Mesholamgately, Jill M Goldstein, Marek Kubicki, Joanne WojcikAbstract:The Lateral and third Ventricles, as well as the corpus callosum (CC), are known to be affected in schizophrenia. Here we investigate whether abnormalities in the Lateral Ventricles (LVs), third ventricle, and corpus callosum are related to one another in first episode schizophrenia (FESZ), and whether such abnormalities show progression over time. Nineteen FESZ and 19 age- and handedness-matched controls were included in the study. MR images were acquired on a 3-Tesla MRI at baseline and ~1.2 years later. FreeSurfer v.5.3 was employed for segmentation. Two-way or univariate ANCOVAs were used for statistical analysis, where the covariate was intracranial volume. Group and gender were included as between-subjects factors. Percent volume changes between baseline and follow-up were used to determine volume changes at follow-up. BiLateral LV and third ventricle volumes were significantly increased, while central CC volume was significantly decreased in patients compared to controls at baseline and at follow-up. In FESZ, the biLateral LV volume was also inversely correlated with volume of the central CC. This inverse correlation was not present in controls. In FESZ, an inverse correlation was found between percent volume increase from baseline to follow-up for biLateral LVs and lesser improvement in the Global Assessment of Functioning score. Significant correlations were observed for abnormalities of central CC, LVs and third ventricle volumes in FESZ, suggesting a common neurodevelopmental origin in schizophrenia. Enlargement of Ventricles was associated with less improvement in global functioning over time.
