The Experts below are selected from a list of 6312 Experts worldwide ranked by ideXlab platform
Yoshimi Fukuoka - One of the best experts on this subject based on the ideXlab platform.
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a weight loss intervention using a commercial mobile application in Latino Americans adelgaza trial
Translational behavioral medicine, 2018Co-Authors: Yoshimi Fukuoka, Eric Vittinghoff, Julie HooperAbstract:More than half of Latino adults living in the USA are expected to develop type 2 diabetes in their lifetime. Despite the growing interest in smartphone use for weight loss and diabetes prevention, relatively few clinical trials have evaluated the efficacy of mobile app-based interventions in Latino populations. The aim of this study was to evaluate the potential efficacy of an in-person weight loss intervention in conjunction with a commercially available Fitbit app in a Latino sample at risk for type 2 diabetes and explore significant predictors associated with weight loss. After the run-in period, 54 self-identified Latinos with body mass index (BMI) > 24.9 kg/m2 were enrolled in an 8-week uncontrolled pilot study, and received a Fitbit Zip, its app, and two in-person weight loss sessions adapted from the Diabetes Prevention Program. Mean age was 45.3 (SD ± 10.8) years, 61.1% were born in the USA, and mean BMI was 31.4 (SD ± 4.1) kg/m2. Participants lost an average of 3.3 (SD ± 3.4) % of their body weight (p < .0005). We also observed statistically significant reductions in hip and waist circumferences, and systolic and diastolic blood pressure (p < .001). After controlling for demographic factors, use of the mobile app weight diary at least twice a week (p = .01) and change in the International Physical Activity Questionnaire score (p = .03) were associated with change in percent body weight. The intervention showed the potential efficacy of this intervention, which should be formally evaluated in a randomized controlled trial.
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abstract p030 a weight loss intervention using a commercial mobile application in Latino Americans adelgaza trial
Circulation, 2018Co-Authors: Yoshimi Fukuoka, Eric Vittinghoff, Julie HooperAbstract:Background: Latinos have the highest prevalence of overweight or obesity (77.1%) when compared with other racial/ethnic groups in the United States. More than half of Latino adults living in the Un...
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family history and body mass index predict perceived risks of diabetes and heart attack among community dwelling caucasian filipino korean and Latino Americans dilh survey
Diabetes Research and Clinical Practice, 2015Co-Authors: Yoshimi Fukuoka, Melinda S Bender, Jiwon Choi, Prisila Gonzalez, Shoshana AraiAbstract:d i a b e t e s r e s e a r c h a n d c l i n i c a l p r a c t i c e 1 0 9 ( 2 0 1 5 ) 1 5 7 - 1 6 3 a b s t r a c t Aim: The purpose of the study was to explore the perceived risk for diabetes and heart attack and associated health status of Caucasian, Filipino, Korean, and Latino Americans without diabetes. Methods: A cross-sectional survey was conducted with 904 urban adults (mean age 44.3 � 16.1 years; 64.3% female) in English, Spanish or Korean between August and Decem- ber 2013. Results: Perceived risk for developing diabetes was indicated by 46.5% (n = 421), and 14.3% (n = 129) perceived themselves to be at risk for having a heart attack in their lifetime. Significant predictors of pessimistic diabetes risk perceptions: Filipino (adjusted odds ratio (AOR) = 1.7; 95% CI: 1.04-2.86) and Korean (AOR = 2.4; 1.33-4.48) ethnicity, family history of diabetes (AOR = 1.4; 1.00-1.84), female gender (AOR = 1.4; 1.04-1.96), high cholesterol (AOR= 1.6; 1.09-2.37) and higher body mass index (BMI) (AOR = 1.1; 1.08-1.15). Predictors of pessi- mistic heart attack risk perceptions were family history of an early heart attack (AOR = 2.9; 1.69-5.02), high blood pressure (AOR = 2.4; 1.45-3.84), and higher BMI (AOR = 1.1; 1.04-1.12) after controlling for socio-demographic factors. Older age, physical inactivity, smoking, and low HDL levels were not associated with risk perceptions. Conclusion: Multiple risk factors were predictive of greater perceived diabetes risk, whereas, only family history of heart attack, high blood pressure and increases in BMI significantly contributed to perceived risk of heart attack among ethnically diverse at risk middle-aged adults. It is important that healthcare providers address the discordance between an individual's risk perceptions and the presence of actual risk factors.
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digital technology ownership usage and factors predicting downloading health apps among caucasian filipino korean and Latino Americans the digital link to health survey
Jmir mhealth and uhealth, 2014Co-Authors: Melinda S Bender, Shoshana Arai, Jiwon Choi, Steven M Paul, Prisila Gonzalez, Yoshimi FukuokaAbstract:Background: Interventions using mobile health (mHealth) apps have been effective in promoting healthy lifestyle behavior change and hold promise in improving health outcomes to thereby reduce health disparities among diverse racial/ethnic populations, particularly Latino and Asian American subgroups (Filipinos and Koreans) at high risk for diabetes and cardiovascular disease. Latinos and Asian Americans are avid digital technology owners and users. However, limited datasets exist regarding digital technology ownership and use, especially among specific racial/ethnic subgroups. Such information is needed to inform development of culturally tailored mHealth tools for use with lifestyle interventions promoting healthy behaviors for these at-risk racial/ethnic populations. Objective: The intent of the study was to examine (1) digital technology ownership and usage, and (2) factors predicting downloading health apps for Caucasian, Filipino, Korean, and Latino American subgroups. Methods: A cross-sectional survey conducted in August 2013 through December 2013 recruited 904 participants (Caucasians n=172, Filipinos n=250, Koreans n=234, and Latinos n=248), age >18 years, from California community events, clinics, churches, and online. English, Spanish, and Korean surveys were administered via paper or online. Descriptive statistics characterized the sociodemographics and digital technology ownership/usage of the 904 participants. Differences among groups in categorical variables were examined using chi-square statistics. Logistic regression was used to determine factors predicting downloading health apps. Results: Overall, mean age was 44 years (SD 16.1), with 64.3% (581/904) female. Only 44.7% (404/904) of all participants reported English as their primary language (Caucasian 98.3%, 169/172; Filipino 67.6%, 169/250; Korean 9.4%, 22/234, and Latino 17.7%, 44/248. Overall, mobile phone ownership was 92.8% (839/904). Compared to all groups, Koreans were more likely to own a mobile phone (82.8%, 194/234), computer (91.4%, 214/234), or tablet (55.2%, 129/234), whereas Latinos (67.5%, 167/248; 65.3%, 162/248; 24.4%, 61/248, respectively) were least likely. Internet access via mobile phones (90.5%, 818/904) was higher than computers (78.6%, 711/904). Odds of downloading health apps increased with college (OR 2.62, 95% CI 1.44-4.80) or graduate school (OR 2.93, 95% CI 1.43-6.00) compared to some high school; and family history of heart attack (OR 2.02, 95% CI 1.16-3.51). Odds of downloading health apps were reduced with: race/ethnicity, Latino (OR 0.37, 95% CI 0.20-0.69), and Korean (OR 0.52, 95% CI 0.31-0.88) compared to Caucasians; increasing age (OR 0.96, 95% CI 0.95-0.97); and completing paper surveys (OR 0.50, 95% CI 0.34-0.75). Conclusions: This survey study uniquely targeted specific racial/ethnic subgroups. Results indicated that despite a narrowing racial/ethnic “digital divide”, some disparities still exist, particularly among racial/ethnic groups with less education and whose primary language is not English. Findings will be used to inform development and evaluation of culturally tailored mHealth apps for use with interventions promoting healthy behavior change for Filipinos, Koreans, and Latinos. [JMIR Mhealth Uhealth 2014;2(4):e43]
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digital technology ownership usage and factors predicting downloading health apps among caucasian filipino korean and Latino Americans the digital link to health survey
Jmir mhealth and uhealth, 2014Co-Authors: Melinda S Bender, Shoshana Arai, Jiwon Choi, Steven M Paul, Prisila Gonzalez, Yoshimi FukuokaAbstract:Background: Interventions using mobile health (mHealth) apps have been effective in promoting healthy lifestyle behavior change and hold promise in improving health outcomes to thereby reduce health disparities among diverse racial/ethnic populations, particularly Latino and Asian American subgroups (Filipinos and Koreans) at high risk for diabetes and cardiovascular disease. Latinos and Asian Americans are avid digital technology owners and users. However, limited datasets exist regarding digital technology ownership and use, especially among specific racial/ethnic subgroups. Such information is needed to inform development of culturally tailored mHealth tools for use with lifestyle interventions promoting healthy behaviors for these at-risk racial/ethnic populations. Objective: The intent of the study was to examine (1) digital technology ownership and usage, and (2) factors predicting downloading health apps for Caucasian, Filipino, Korean, and Latino American subgroups. Methods: A cross-sectional survey conducted in August 2013 through December 2013 recruited 904 participants (Caucasians n=172, Filipinos n=250, Koreans n=234, and Latinos n=248), age >18 years, from California community events, clinics, churches, and online. English, Spanish, and Korean surveys were administered via paper or online. Descriptive statistics characterized the sociodemographics and digital technology ownership/usage of the 904 participants. Differences among groups in categorical variables were examined using chi-square statistics. Logistic regression was used to determine factors predicting downloading health apps. Results: Overall, mean age was 44 years (SD 16.1), with 64.3% (581/904) female. Only 44.7% (404/904) of all participants reported English as their primary language (Caucasian 98.3%, 169/172; Filipino 67.6%, 169/250; Korean 9.4%, 22/234, and Latino 17.7%, 44/248. Overall, mobile phone ownership was 92.8% (839/904). Compared to all groups, Koreans were more likely to own a mobile phone (82.8%, 194/234), computer (91.4%, 214/234), or tablet (55.2%, 129/234), whereas Latinos (67.5%, 167/248; 65.3%, 162/248; 24.4%, 61/248, respectively) were least likely. Internet access via mobile phones (90.5%, 818/904) was higher than computers (78.6%, 711/904). Odds of downloading health apps increased with college (OR 2.62, 95% CI 1.44-4.80) or graduate school (OR 2.93, 95% CI 1.43-6.00) compared to some high school; and family history of heart attack (OR 2.02, 95% CI 1.16-3.51). Odds of downloading health apps were reduced with: race/ethnicity, Latino (OR 0.37, 95% CI 0.20-0.69), and Korean (OR 0.52, 95% CI 0.31-0.88) compared to Caucasians; increasing age (OR 0.96, 95% CI 0.95-0.97); and completing paper surveys (OR 0.50, 95% CI 0.34-0.75). Conclusions: This survey study uniquely targeted specific racial/ethnic subgroups. Results indicated that despite a narrowing racial/ethnic “digital divide”, some disparities still exist, particularly among racial/ethnic groups with less education and whose primary language is not English. Findings will be used to inform development and evaluation of culturally tailored mHealth apps for use with interventions promoting healthy behavior change for Filipinos, Koreans, and Latinos. [JMIR Mhealth Uhealth 2014;2(4):e43]
Tamar Sofer - One of the best experts on this subject based on the ideXlab platform.
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admixture mapping identifies novel loci for obstructive sleep apnea in hispanic Latino Americans
Human Molecular Genetics, 2019Co-Authors: Brian E Cade, Han Chen, Tamar Sofer, Heming Wang, Scott A Sands, Sharon R BrowningAbstract:Obstructive sleep apnea (OSA) is a common disorder associated with increased risk of cardiovascular disease and mortality. Its prevalence and severity vary across ancestral background. Although OSA traits are heritable, few genetic associations have been identified. To identify genetic regions associated with OSA and improve statistical power, we applied admixture mapping on three primary OSA traits [the apnea hypopnea index (AHI), overnight average oxyhemoglobin saturation (SaO2) and percentage time SaO2 < 90%] and a secondary trait (respiratory event duration) in a Hispanic/Latino American population study of 11 575 individuals with significant variation in ancestral background. Linear mixed models were performed using previously inferred African, European and Amerindian local genetic ancestry markers. Global African ancestry was associated with a lower AHI, higher SaO2 and shorter event duration. Admixture mapping analysis of the primary OSA traits identified local African ancestry at the chromosomal region 2q37 as genome-wide significantly associated with AHI (P < 5.7 × 10-5), and European and Amerindian ancestries at 18q21 suggestively associated with both AHI and percentage time SaO2 < 90% (P < 10-3). Follow-up joint ancestry-SNP association analyses identified novel variants in ferrochelatase (FECH), significantly associated with AHI and percentage time SaO2 < 90% after adjusting for multiple tests (P < 8 × 10-6). These signals contributed to the admixture mapping associations and were replicated in independent cohorts. In this first admixture mapping study of OSA, novel associations with variants in the iron/heme metabolism pathway suggest a role for iron in influencing respiratory traits underlying OSA.
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genome wide association study of blood pressure traits by hispanic Latino background the hispanic community health study study of Latinos
Scientific Reports, 2017Co-Authors: Tamar Sofer, Quenna Wong, Fernando Pires Hartwig, Kent D Taylor, Helen R Warren, Evangelos Evangelou, Claudia P CabreraAbstract:Hypertension prevalence varies between ethnic groups, possibly due to differences in genetic, environmental, and cultural determinants. Hispanic/Latino Americans are a diverse and understudied population. We performed a genome-wide association study (GWAS) of blood pressure (BP) traits in 12,278 participants from the Hispanics Community Health Study/Study of Latinos (HCHS/SOL). In the discovery phase we identified eight previously unreported BP loci. In the replication stage, we tested these loci in the 1982 Pelotas Birth Cohort Study of admixed Southern Brazilians, the COGENT-BP study of African descent, women of European descent from the Women Health Initiative (WHI), and a sample of European descent from the UK Biobank. No loci met the Bonferroni-adjusted level of statistical significance (0.0024). Two loci had marginal evidence of replication: rs78701042 (NGF) with diastolic BP (P = 0.008 in the 1982 Pelotas Birth Cohort Study), and rs7315692 (SLC5A8) with systolic BP (P = 0.007 in European ancestry replication). We investigated whether previously reported loci associated with BP in studies of European, African, and Asian ancestry generalize to Hispanics/Latinos. Overall, 26% of the known associations in studies of individuals of European and Chinese ancestries generalized, while only a single association previously discovered in a people of African descent generalized.
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genetic associations with obstructive sleep apnea traits in hispanic Latino Americans
American Journal of Respiratory and Critical Care Medicine, 2016Co-Authors: Brian E Cade, Adrienne M Stilp, Han Chen, Kevin J Gleason, Tamar Sofer, Sonia Ancoliisrael, Raanan Arens, Graeme I Bell, Jennifer E Below, Andrew BjonnesAbstract:Rationale: Obstructive sleep apnea is a common disorder associated with increased risk for cardiovascular disease, diabetes, and premature mortality. Although there is strong clinical and epidemiologic evidence supporting the importance of genetic factors in influencing obstructive sleep apnea, its genetic basis is still largely unknown. Prior genetic studies focused on traits defined using the apnea–hypopnea index, which contains limited information on potentially important genetically determined physiologic factors, such as propensity for hypoxemia and respiratory arousability.Objectives: To define novel obstructive sleep apnea genetic risk loci for obstructive sleep apnea, we conducted genome-wide association studies of quantitative traits in Hispanic/Latino Americans from three cohorts.Methods: Genome-wide data from as many as 12,558 participants in the Hispanic Community Health Study/Study of Latinos, Multi-Ethnic Study of Atherosclerosis, and Starr County Health Studies population-based cohorts were...
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genome wide association study of platelet count identifies ancestry specific loci in hispanic Latino Americans
American Journal of Human Genetics, 2016Co-Authors: Deepti Jain, Chani J Hodonsky, Ursula M Schick, Jean Morrison, Lisa M Brown, Tamar Sofer, Matthew P Conomos, James P Davis, Claudia SchurmannAbstract:Platelets play an essential role in hemostasis and thrombosis. We performed a genome-wide association study of platelet count in 12,491 participants of the Hispanic Community Health Study/Study of Latinos by using a mixed-model method that accounts for admixture and family relationships. We discovered and replicated associations with five genes (ACTN1, ETV7, GABBR1-MOG, MEF2C, and ZBTB9-BAK1). Our strongest association was with Amerindian-specific variant rs117672662 (p value = 1.16 × 10−28) in ACTN1, a gene implicated in congenital macrothrombocytopenia. rs117672662 exhibited allelic differences in transcriptional activity and protein binding in hematopoietic cells. Our results underscore the value of diverse populations to extend insights into the allelic architecture of complex traits.
Adrienne M Stilp - One of the best experts on this subject based on the ideXlab platform.
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a meta analysis of genome wide association studies of asthma in puerto ricans
European Respiratory Journal, 2017Co-Authors: J. Magos Brehm, Maria Pinoyanes, Sam S Oh, Cathy C. Laurie, Benjamin A Raby, Erick Forno, Edna Acostaperez, Michelle M. Cloutier, Adrienne M StilpAbstract:Puerto Ricans are disproportionately affected with asthma in the USA. In this study, we aim to identify genetic variants that confer susceptibility to asthma in Puerto Ricans. We conducted a meta-analysis of genome-wide association studies (GWAS) of asthma in Puerto Ricans, including participants from: the Genetics of Asthma in Latino Americans (GALA) I-II, the Hartford–Puerto Rico Study and the Hispanic Community Health Study. Moreover, we examined whether susceptibility loci identified in previous meta-analyses of GWAS are associated with asthma in Puerto Ricans. The only locus to achieve genome-wide significance was chromosome 17q21, as evidenced by our top single nucleotide polymorphism (SNP), rs907092 (OR 0.71, p=1.2×10−12) at IKZF3 . Similar to results in non-Puerto Ricans, SNPs in genes in the same linkage disequilibrium block as IKZF3 ( e.g. ZPBP2 , ORMDL3 and GSDMB ) were significantly associated with asthma in Puerto Ricans. With regard to results from a meta-analysis in Europeans, we replicated findings for rs2305480 at GSDMB , but not for SNPs in any other genes. On the other hand, we replicated results from a meta-analysis of North American populations for SNPs at IL1RL1 , TSLP and GSDMB but not for IL33 . Our findings suggest that common variants on chromosome 17q21 have the greatest effects on asthma in Puerto Ricans. Common allelic variants on chromosome 17q21 have the greatest effects on asthma in Puerto Ricans, a high-risk group
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genetic associations with obstructive sleep apnea traits in hispanic Latino Americans
American Journal of Respiratory and Critical Care Medicine, 2016Co-Authors: Brian E Cade, Adrienne M Stilp, Han Chen, Kevin J Gleason, Tamar Sofer, Sonia Ancoliisrael, Raanan Arens, Graeme I Bell, Jennifer E Below, Andrew BjonnesAbstract:Rationale: Obstructive sleep apnea is a common disorder associated with increased risk for cardiovascular disease, diabetes, and premature mortality. Although there is strong clinical and epidemiologic evidence supporting the importance of genetic factors in influencing obstructive sleep apnea, its genetic basis is still largely unknown. Prior genetic studies focused on traits defined using the apnea–hypopnea index, which contains limited information on potentially important genetically determined physiologic factors, such as propensity for hypoxemia and respiratory arousability.Objectives: To define novel obstructive sleep apnea genetic risk loci for obstructive sleep apnea, we conducted genome-wide association studies of quantitative traits in Hispanic/Latino Americans from three cohorts.Methods: Genome-wide data from as many as 12,558 participants in the Hispanic Community Health Study/Study of Latinos, Multi-Ethnic Study of Atherosclerosis, and Starr County Health Studies population-based cohorts were...
Maria Pinoyanes - One of the best experts on this subject based on the ideXlab platform.
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a meta analysis of genome wide association studies of asthma in puerto ricans
European Respiratory Journal, 2017Co-Authors: J. Magos Brehm, Maria Pinoyanes, Sam S Oh, Cathy C. Laurie, Benjamin A Raby, Erick Forno, Edna Acostaperez, Michelle M. Cloutier, Adrienne M StilpAbstract:Puerto Ricans are disproportionately affected with asthma in the USA. In this study, we aim to identify genetic variants that confer susceptibility to asthma in Puerto Ricans. We conducted a meta-analysis of genome-wide association studies (GWAS) of asthma in Puerto Ricans, including participants from: the Genetics of Asthma in Latino Americans (GALA) I-II, the Hartford–Puerto Rico Study and the Hispanic Community Health Study. Moreover, we examined whether susceptibility loci identified in previous meta-analyses of GWAS are associated with asthma in Puerto Ricans. The only locus to achieve genome-wide significance was chromosome 17q21, as evidenced by our top single nucleotide polymorphism (SNP), rs907092 (OR 0.71, p=1.2×10−12) at IKZF3 . Similar to results in non-Puerto Ricans, SNPs in genes in the same linkage disequilibrium block as IKZF3 ( e.g. ZPBP2 , ORMDL3 and GSDMB ) were significantly associated with asthma in Puerto Ricans. With regard to results from a meta-analysis in Europeans, we replicated findings for rs2305480 at GSDMB , but not for SNPs in any other genes. On the other hand, we replicated results from a meta-analysis of North American populations for SNPs at IL1RL1 , TSLP and GSDMB but not for IL33 . Our findings suggest that common variants on chromosome 17q21 have the greatest effects on asthma in Puerto Ricans. Common allelic variants on chromosome 17q21 have the greatest effects on asthma in Puerto Ricans, a high-risk group
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air pollution and lung function in minority youth with asthma in the gala ii genes environments and admixture in Latino Americans and sage ii study of african Americans asthma genes and environments studies
American Journal of Respiratory and Critical Care Medicine, 2016Co-Authors: Andreas M Neophytou, Neeta Thakur, Maria Pinoyanes, Joshua M Galanter, Christopher R Gignoux, Dara G Torgerson, Celeste Eng, Katherine K Nishimura, Marquitta J White, Elizabeth A NguyenAbstract:Rationale: Adverse effects of exposures to ambient air pollution on lung function are well documented, but evidence in racial/ethnic minority children is lacking.Objectives: To assess the relationship between air pollution and lung function in minority children with asthma and possible modification by global genetic ancestry.Methods: The study population consisted of 1,449 Latino and 519 African American children with asthma from five different geographical regions in the mainland United States and Puerto Rico. We examined five pollutants (particulate matter ≤10 μm and ≤2.5 μm in diameter, ozone, nitrogen dioxide, and sulfur dioxide), derived from participant residential history and ambient air monitoring data, and assessed over several time windows. We fit generalized additive models for associations between pollutant exposures and lung function parameters and tested for interaction terms between exposures and genetic ancestry.Measurements and Main Results: A 5 μg/m3 increase in average lifetime particul...
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genome wide association study and admixture mapping reveal new loci associated with total ige levels in Latinos
The Journal of Allergy and Clinical Immunology, 2015Co-Authors: Maria Pinoyanes, Albert M. Levin, Joshua M Galanter, Christopher R Gignoux, Celeste Eng, Scott Huntsman, Catarina D Campbell, Katherine K Nishimura, Pierreantoine GourraudAbstract:Background IgE is a key mediator of allergic inflammation, and its levels are frequently increased in patients with allergic disorders. Objective We sought to identify genetic variants associated with IgE levels in Latinos. Methods We performed a genome-wide association study and admixture mapping of total IgE levels in 3334 Latinos from the Genes-environments & Admixture in Latino Americans (GALA II) study. Replication was evaluated in 454 Latinos, 1564 European Americans, and 3187 African Americans from independent studies. Results We confirmed associations of 6 genes identified by means of previous genome-wide association studies and identified a novel genome-wide significant association of a polymorphism in the zinc finger protein 365 gene (ZNF365) with total IgE levels (rs200076616, P = 2.3 × 10 −8 ). We next identified 4 admixture mapping peaks (6p21.32-p22.1, 13p22-31, 14q23.2, and 22q13.1) at which local African, European, and/or Native American ancestry was significantly associated with IgE levels. The most significant peak was 6p21.32-p22.1, where Native American ancestry was associated with lower IgE levels ( P = 4.95 × 10 −8 ). All but 22q13.1 were replicated in an independent sample of Latinos, and 2 of the peaks were replicated in African Americans (6p21.32-p22.1 and 14q23.2). Fine mapping of 6p21.32-p22.1 identified 6 genome-wide significant single nucleotide polymorphisms in Latinos, 2 of which replicated in European Americans. Another single nucleotide polymorphism was peak-wide significant within 14q23.2 in African Americans (rs1741099, P = 3.7 × 10 −6 ) and replicated in non–African American samples ( P = .011). Conclusion We confirmed genetic associations at 6 genes and identified novel associations within ZNF365 , HLA-DQA1 , and 14q23.2. Our results highlight the importance of studying diverse multiethnic populations to uncover novel loci associated with total IgE levels.
Julie Hooper - One of the best experts on this subject based on the ideXlab platform.
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a weight loss intervention using a commercial mobile application in Latino Americans adelgaza trial
Translational behavioral medicine, 2018Co-Authors: Yoshimi Fukuoka, Eric Vittinghoff, Julie HooperAbstract:More than half of Latino adults living in the USA are expected to develop type 2 diabetes in their lifetime. Despite the growing interest in smartphone use for weight loss and diabetes prevention, relatively few clinical trials have evaluated the efficacy of mobile app-based interventions in Latino populations. The aim of this study was to evaluate the potential efficacy of an in-person weight loss intervention in conjunction with a commercially available Fitbit app in a Latino sample at risk for type 2 diabetes and explore significant predictors associated with weight loss. After the run-in period, 54 self-identified Latinos with body mass index (BMI) > 24.9 kg/m2 were enrolled in an 8-week uncontrolled pilot study, and received a Fitbit Zip, its app, and two in-person weight loss sessions adapted from the Diabetes Prevention Program. Mean age was 45.3 (SD ± 10.8) years, 61.1% were born in the USA, and mean BMI was 31.4 (SD ± 4.1) kg/m2. Participants lost an average of 3.3 (SD ± 3.4) % of their body weight (p < .0005). We also observed statistically significant reductions in hip and waist circumferences, and systolic and diastolic blood pressure (p < .001). After controlling for demographic factors, use of the mobile app weight diary at least twice a week (p = .01) and change in the International Physical Activity Questionnaire score (p = .03) were associated with change in percent body weight. The intervention showed the potential efficacy of this intervention, which should be formally evaluated in a randomized controlled trial.
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abstract p030 a weight loss intervention using a commercial mobile application in Latino Americans adelgaza trial
Circulation, 2018Co-Authors: Yoshimi Fukuoka, Eric Vittinghoff, Julie HooperAbstract:Background: Latinos have the highest prevalence of overweight or obesity (77.1%) when compared with other racial/ethnic groups in the United States. More than half of Latino adults living in the Un...