The Experts below are selected from a list of 177 Experts worldwide ranked by ideXlab platform
J M Thomas - One of the best experts on this subject based on the ideXlab platform.
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CASE REPORT: Leiomyoblastoma of the colon presenting aspseudo-Meigs» syndrome
Ejso, 1999Co-Authors: Y.p. Koak, J M ThomasAbstract:Abstract Leiomyoblastomas are rare smooth-muscle tumours, most commonly arising from the stomach wall. We describe a case of Leiomyoblastoma of the colon presenting with the pseudo-Meigs» syndrome.
A A Kyriazis - One of the best experts on this subject based on the ideXlab platform.
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uterine Leiomyoblastoma epithelioid leiomyoma neoplasm of low grade malignancy a histopathologic study
Archives of Pathology & Laboratory Medicine, 1992Co-Authors: A P Kyriazis, A A KyriazisAbstract:Uterine Leiomyoblastomas are neoplasms of smooth muscle origin, which despite their benign histopathologic characteristics, have been shown to invade locally, metastasize, and recur, resulting in the patient's death. In an effort to define possible cellular changes that could explain the disparity between histopathologic features and biologic behavior, we have studied a series of three uterine Leiomyoblastomas that, in routine sections, exhibited benign morphological characteristics. A detailed histopathologic study revealed, in all three cases, randomly distributed clusters of neoplastic cells with overt malignant features, such as cellular and nuclear atypia, abnormal mitoses, local infiltrating tendencies, and vascular invasion. These findings suggest that uterine Leiomyoblastomas should be viewed as neoplasms of low-grade malignancy of a distinct clinicopathologic entity.
Y.p. Koak - One of the best experts on this subject based on the ideXlab platform.
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CASE REPORT: Leiomyoblastoma of the colon presenting aspseudo-Meigs» syndrome
Ejso, 1999Co-Authors: Y.p. Koak, J M ThomasAbstract:Abstract Leiomyoblastomas are rare smooth-muscle tumours, most commonly arising from the stomach wall. We describe a case of Leiomyoblastoma of the colon presenting with the pseudo-Meigs» syndrome.
A P Kyriazis - One of the best experts on this subject based on the ideXlab platform.
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uterine Leiomyoblastoma epithelioid leiomyoma neoplasm of low grade malignancy a histopathologic study
Archives of Pathology & Laboratory Medicine, 1992Co-Authors: A P Kyriazis, A A KyriazisAbstract:Uterine Leiomyoblastomas are neoplasms of smooth muscle origin, which despite their benign histopathologic characteristics, have been shown to invade locally, metastasize, and recur, resulting in the patient's death. In an effort to define possible cellular changes that could explain the disparity between histopathologic features and biologic behavior, we have studied a series of three uterine Leiomyoblastomas that, in routine sections, exhibited benign morphological characteristics. A detailed histopathologic study revealed, in all three cases, randomly distributed clusters of neoplastic cells with overt malignant features, such as cellular and nuclear atypia, abnormal mitoses, local infiltrating tendencies, and vascular invasion. These findings suggest that uterine Leiomyoblastomas should be viewed as neoplasms of low-grade malignancy of a distinct clinicopathologic entity.
Johan Bulten - One of the best experts on this subject based on the ideXlab platform.
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Uterine malignant Leiomyoblastoma (epithelioid leiomyosarcoma) during pregnancy.
Gynecologic oncology, 1999Co-Authors: R.l.m. Bekkers, L.f.a.g. Massuger, P.p.v.d. Berg, U.g.j.m.v. Haelst, Johan BultenAbstract:A case of uterine malignant Leiomyoblastoma (UML) which was initially mistaken for uterine leiomyoma on two different occasions is presented. About 20 cases of uterine Leiomyoblastoma taking a malignant course have been described in the literature. This case of UML is the first diagnosed during pregnancy. In retrospect, tumor tissue removed from the uterus 4 years earlier already showed histological signs of UML. The large and metastatic tumor showed nuclear atypia, a moderate mitotic index, and tumor cell necrosis, indicating malignancy. Treatment consisted of hysterectomy, bilateral salpingo-oophorectomy, and debulking of most other tumor masses. In the literature, radio- and chemotherapy have not proved to be effective in these tumors. Hormonal therapy has only been used in 2 patients. In this patient, hormonal influence on tumor growth may be substantial. The tumor was progesterone- and estrogen-receptor positive and increased in size rapidly during pregnancy. Since little is known about these tumors further studies are necessary to evaluate hormonal influences both as a causative factor and as a therapeutic possibility.