The Experts below are selected from a list of 77202 Experts worldwide ranked by ideXlab platform
Juan David Ramírez - One of the best experts on this subject based on the ideXlab platform.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania ( Viannia ) braziliensis and Leishmania ( Viannia ) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis. Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania (Viannia) braziliensis and Leishmania (Viannia) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis . Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease. Methods Seven previously described genetic markers were selected highlighting the implementation of a mitochondrial marker. Markers were applied to 163 samples from isolates obtained between 1980 and 2001. Results The identification of the samples showed an excellent correlation with typing tests previously applied (MLEE, monoclonal antibodies). Isolates of L. braziliensis showed greater genetic diversity than L. panamensis , and a greater number of diploid sequence types (DSTs). In addition, the geographical distribution of DSTs for each species were obtained through georeferencing maps. Conclusions To our knowldge, this study represents the first description of the genetic variability of L. panamensis in Colombia and South America, and is the first to propose a scheme of MLST for epidemiological surveillance of Leishmaniasis in the country.
Giovanny Herrera - One of the best experts on this subject based on the ideXlab platform.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania ( Viannia ) braziliensis and Leishmania ( Viannia ) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis. Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania (Viannia) braziliensis and Leishmania (Viannia) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis . Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease. Methods Seven previously described genetic markers were selected highlighting the implementation of a mitochondrial marker. Markers were applied to 163 samples from isolates obtained between 1980 and 2001. Results The identification of the samples showed an excellent correlation with typing tests previously applied (MLEE, monoclonal antibodies). Isolates of L. braziliensis showed greater genetic diversity than L. panamensis , and a greater number of diploid sequence types (DSTs). In addition, the geographical distribution of DSTs for each species were obtained through georeferencing maps. Conclusions To our knowldge, this study represents the first description of the genetic variability of L. panamensis in Colombia and South America, and is the first to propose a scheme of MLST for epidemiological surveillance of Leishmaniasis in the country.
Carolina Flórez - One of the best experts on this subject based on the ideXlab platform.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania ( Viannia ) braziliensis and Leishmania ( Viannia ) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis. Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania (Viannia) braziliensis and Leishmania (Viannia) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis . Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease. Methods Seven previously described genetic markers were selected highlighting the implementation of a mitochondrial marker. Markers were applied to 163 samples from isolates obtained between 1980 and 2001. Results The identification of the samples showed an excellent correlation with typing tests previously applied (MLEE, monoclonal antibodies). Isolates of L. braziliensis showed greater genetic diversity than L. panamensis , and a greater number of diploid sequence types (DSTs). In addition, the geographical distribution of DSTs for each species were obtained through georeferencing maps. Conclusions To our knowldge, this study represents the first description of the genetic variability of L. panamensis in Colombia and South America, and is the first to propose a scheme of MLST for epidemiological surveillance of Leishmaniasis in the country.
Aníbal A. Teherán - One of the best experts on this subject based on the ideXlab platform.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania ( Viannia ) braziliensis and Leishmania ( Viannia ) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis. Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania (Viannia) braziliensis and Leishmania (Viannia) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis . Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease. Methods Seven previously described genetic markers were selected highlighting the implementation of a mitochondrial marker. Markers were applied to 163 samples from isolates obtained between 1980 and 2001. Results The identification of the samples showed an excellent correlation with typing tests previously applied (MLEE, monoclonal antibodies). Isolates of L. braziliensis showed greater genetic diversity than L. panamensis , and a greater number of diploid sequence types (DSTs). In addition, the geographical distribution of DSTs for each species were obtained through georeferencing maps. Conclusions To our knowldge, this study represents the first description of the genetic variability of L. panamensis in Colombia and South America, and is the first to propose a scheme of MLST for epidemiological surveillance of Leishmaniasis in the country.
Martha S. Ayala - One of the best experts on this subject based on the ideXlab platform.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania ( Viannia ) braziliensis and Leishmania ( Viannia ) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis. Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease.
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Evaluation of a Multilocus Sequence Typing (MLST) scheme for Leishmania (Viannia) braziliensis and Leishmania (Viannia) panamensis in Colombia
Parasites & Vectors, 2017Co-Authors: Giovanny Herrera, Carolina Hernández, Martha S. Ayala, Carolina Flórez, Aníbal A. Teherán, Juan David RamírezAbstract:Background Leishmaniases are parasitic vector-borne diseases affecting more than 12 million people in 98 countries. In Colombia, Leishmaniasis is widespread and the most common clinical manifestation is cutaneous, mainly caused by L. panamensis and L. braziliensis . Currently, the genetic diversity of these species in Colombia is unknown. To address this, we applied molecular techniques for their characterization, using multilocus sequence typing (MLST) to explore the genetic variability and phylodynamics of the disease. Methods Seven previously described genetic markers were selected highlighting the implementation of a mitochondrial marker. Markers were applied to 163 samples from isolates obtained between 1980 and 2001. Results The identification of the samples showed an excellent correlation with typing tests previously applied (MLEE, monoclonal antibodies). Isolates of L. braziliensis showed greater genetic diversity than L. panamensis , and a greater number of diploid sequence types (DSTs). In addition, the geographical distribution of DSTs for each species were obtained through georeferencing maps. Conclusions To our knowldge, this study represents the first description of the genetic variability of L. panamensis in Colombia and South America, and is the first to propose a scheme of MLST for epidemiological surveillance of Leishmaniasis in the country.
