The Experts below are selected from a list of 168 Experts worldwide ranked by ideXlab platform

Shengxiang Xiao - One of the best experts on this subject based on the ideXlab platform.

  • quality of life in patients with Lepromatous Leprosy in china
    Journal of The European Academy of Dermatology and Venereology, 2009
    Co-Authors: Shengxiang Xiao, S B Xiao, F Yang
    Abstract:

    Background  Leprosy has an impact on patients’ quality of life (QoL). However, there has been no study specifically on the impact of the severest type of Leprosy-Lepromatous Leprosy on QoL. Objective  To describe the use of Dermatology Life Quality Index (DLQI) among patients with Lepromatous Leprosy in China. Methods  Sixty-four inpatients with Lepromatous Leprosy of Shangluo hospital and Hanzhong hospital and sixty-four controls (healthy volunteers or patients with other dermatoses) matched for age and gender were asked to complete DLQI questionnaires from 2 September 2008 to 20 December 2008. Extensive data were collected besides DLQI, including demographic data and disease-related characteristics. Absence or presence of disability among patients with Lepromatous Leprosy was evaluated at the same time. Results  The overall mean DLQI score for Lepromatous Leprosy (18.78) was higher than that for control (9.00) (P < 0.001). Patients with Lepromatous Leprosy scored significantly higher for all items (P < 0.001) except Q4 (clothes choice). Controls scored significantly lower for all domains of DLQI. Scores of LL increased markedly with increasing clinical severity, but were not associated with educational level, gender, age and disease duration. The inter-item correlation averaged 0.240 and Cronbach’s alpha was 0.759, indicating high internal consistency. Conclusions  This is the first exclusive study to attempt to measure the impact of Lepromatous Leprosy on QoL. Lepromatous Leprosy has a severe impact on QoL.

  • Quality of life in patients with Lepromatous Leprosy in China
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2009
    Co-Authors: Shengxiang Xiao, Yang F
    Abstract:

    Background  Leprosy has an impact on patients’ quality of life (QoL). However, there has been no study specifically on the impact of the severest type of Leprosy-Lepromatous Leprosy on QoL. Objective  To describe the use of Dermatology Life Quality Index (DLQI) among patients with Lepromatous Leprosy in China. Methods  Sixty-four inpatients with Lepromatous Leprosy of Shangluo hospital and Hanzhong hospital and sixty-four controls (healthy volunteers or patients with other dermatoses) matched for age and gender were asked to complete DLQI questionnaires from 2 September 2008 to 20 December 2008. Extensive data were collected besides DLQI, including demographic data and disease-related characteristics. Absence or presence of disability among patients with Lepromatous Leprosy was evaluated at the same time. Results  The overall mean DLQI score for Lepromatous Leprosy (18.78) was higher than that for control (9.00) (P 

Yang F - One of the best experts on this subject based on the ideXlab platform.

  • Quality of life in patients with Lepromatous Leprosy in China
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2009
    Co-Authors: Shengxiang Xiao, Yang F
    Abstract:

    Background  Leprosy has an impact on patients’ quality of life (QoL). However, there has been no study specifically on the impact of the severest type of Leprosy-Lepromatous Leprosy on QoL. Objective  To describe the use of Dermatology Life Quality Index (DLQI) among patients with Lepromatous Leprosy in China. Methods  Sixty-four inpatients with Lepromatous Leprosy of Shangluo hospital and Hanzhong hospital and sixty-four controls (healthy volunteers or patients with other dermatoses) matched for age and gender were asked to complete DLQI questionnaires from 2 September 2008 to 20 December 2008. Extensive data were collected besides DLQI, including demographic data and disease-related characteristics. Absence or presence of disability among patients with Lepromatous Leprosy was evaluated at the same time. Results  The overall mean DLQI score for Lepromatous Leprosy (18.78) was higher than that for control (9.00) (P 

F Yang - One of the best experts on this subject based on the ideXlab platform.

  • quality of life in patients with Lepromatous Leprosy in china
    Journal of The European Academy of Dermatology and Venereology, 2009
    Co-Authors: Shengxiang Xiao, S B Xiao, F Yang
    Abstract:

    Background  Leprosy has an impact on patients’ quality of life (QoL). However, there has been no study specifically on the impact of the severest type of Leprosy-Lepromatous Leprosy on QoL. Objective  To describe the use of Dermatology Life Quality Index (DLQI) among patients with Lepromatous Leprosy in China. Methods  Sixty-four inpatients with Lepromatous Leprosy of Shangluo hospital and Hanzhong hospital and sixty-four controls (healthy volunteers or patients with other dermatoses) matched for age and gender were asked to complete DLQI questionnaires from 2 September 2008 to 20 December 2008. Extensive data were collected besides DLQI, including demographic data and disease-related characteristics. Absence or presence of disability among patients with Lepromatous Leprosy was evaluated at the same time. Results  The overall mean DLQI score for Lepromatous Leprosy (18.78) was higher than that for control (9.00) (P < 0.001). Patients with Lepromatous Leprosy scored significantly higher for all items (P < 0.001) except Q4 (clothes choice). Controls scored significantly lower for all domains of DLQI. Scores of LL increased markedly with increasing clinical severity, but were not associated with educational level, gender, age and disease duration. The inter-item correlation averaged 0.240 and Cronbach’s alpha was 0.759, indicating high internal consistency. Conclusions  This is the first exclusive study to attempt to measure the impact of Lepromatous Leprosy on QoL. Lepromatous Leprosy has a severe impact on QoL.

M Donaghy - One of the best experts on this subject based on the ideXlab platform.

  • Vasculitic neuropathy in a patient with inactive treated Lepromatous Leprosy.
    Journal of neurology neurosurgery and psychiatry, 2000
    Co-Authors: J R C Bowen, A C Mcdougall, J H Morris, Sebastian Lucas, M Donaghy
    Abstract:

    A 46 year old Asian male with previously treated Lepromatous Leprosy developed a stepwise multifocal sensory disturbance 25 years later. Neurophysiology demonstrated marked deterioration from previous studies. Sural nerve biopsy disclosed a vasculitic process superimposed on inactive Lepromatous Leprosy. Immunocytochemical stains for mycobacterial antigen showed deposits within nerve and vessel walls. A delayed vasculitic neuropathy precipitated by persisting mycobacterial antigen is proposed.

J R C Bowen - One of the best experts on this subject based on the ideXlab platform.

  • Vasculitic neuropathy in a patient with inactive treated Lepromatous Leprosy.
    Journal of neurology neurosurgery and psychiatry, 2000
    Co-Authors: J R C Bowen, A C Mcdougall, J H Morris, Sebastian Lucas, M Donaghy
    Abstract:

    A 46 year old Asian male with previously treated Lepromatous Leprosy developed a stepwise multifocal sensory disturbance 25 years later. Neurophysiology demonstrated marked deterioration from previous studies. Sural nerve biopsy disclosed a vasculitic process superimposed on inactive Lepromatous Leprosy. Immunocytochemical stains for mycobacterial antigen showed deposits within nerve and vessel walls. A delayed vasculitic neuropathy precipitated by persisting mycobacterial antigen is proposed.