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Roberta B Ness - One of the best experts on this subject based on the ideXlab platform.

  • Association of Lower Genital Tract Inflammation With Objective Evidence of Endometritis
    2013
    Co-Authors: Jeffrey Peipert, Roberta B Ness, David E. Soper, Debra Bass
    Abstract:

    The purpose of this report is to evaluate the association between lower genital tract inflammation and objectively diagnosed endometritis. We analyzed the first 157 patients enrolled in the PEACH study, a multicenter randomized clinical trial designed to compare the effectiveness of outpatient and inpatient therapy for PID. Women less than 38 years of age, who presented with a history of pelvic discomfort for 30 days or less and who were found to have pelvic organ tenderness (uterine or adnexal tenderness) on bimanual examination, were initially invited to participate. After recruitment of the first 58 patients (group 1) we added the presence of Leukorrhea, mucopurulent cervicitis, or untreated positive test for N. gonorrhoeae or C. trachomatis to the inclusion criteria (group 2, N 99). We compared rates of endometritis in the two groups and calculated the sensitivity, specificity, and predicted values of the presence of white blood cells in the vaginal wet preparation. The rate of upper genital tract infection in group 1 was 46.5 % (27/58) compared to 49.5 % (49/99) in group 2. Microbiologic evidence of either N. gonorrhoeae or C. trachomatis increased from 22.4 % in group 1 to 38.3 % in group 2. The presence of Vaginal white blood cells or mueopus has a high sensitivity (88.9%), but a low specificity (19.4%) for the diagnosis of upper genital-tract infection. Assessment of the lower genital tract for evidence of infection or inflammation is a valuable component of the diagnostic evaluation of pelvic inflammatory disease. The presence of either mucopus or vaginal white blood cells is a highly sensitive test for endometritis in patients with pelvic pain and tenderness

  • mycoplasma genitalium among women with nongonococcal nonchlamydial pelvic inflammatory disease
    Infectious Diseases in Obstetrics & Gynecology, 2006
    Co-Authors: Catherine L Haggerty, Patricia A. Totten, Roberta B Ness
    Abstract:

    Pelvic inflammatory disease (PID) is a frequent condition of young women, often resulting in reproductive morbidity. Although Neisseria gonorrhoeae and/or Chlamydia trachomatis are/is recovered from approximately a third to a half of women with PID, the etiologic agent is often unidentified. We need PCR to test for M genitalium among a pilot sample of 50 women with nongonococcal, nonchlamydial endometritis enrolled in the PID evaluation and clinical health (PEACH) study. All participants had pelvic pain, pelvic organ tenderness, and Leukorrhea, mucopurulent cervicitis, or untreated cervicitis. Endometritis was defined as ≥5 surface epithelium neutrophils per ×400 field absent of menstrual endometrium and/or ≥2 stromal plasma cells per ×120 field. We detected M genitalium in 7 (14%) of the women tested: 6 (12%) in cervical specimens and 4 (8%) in endometrial specimens. We conclude that M genitalium is prevalent in the endometrium of women with nongonococcal, nonchlamydial PID.

  • Clinical Study Mycoplasma Genitalium Among Women With Nongonococcal, Nonchlamydial Pelvic Inflammatory Disease
    2006
    Co-Authors: Catherine L Haggerty, Patricia A. Totten, Sabina G. Astete, Roberta B Ness
    Abstract:

    Pelvic inflammatory disease (PID) is a frequent condition of young women, often resulting in reproductive morbidity. Although Neisseria gonorrhoeae and/or Chlamydia trachomatis are/is recovered from approximately a third to a half of women with PID, the etiologic agent is often unidentified. We need PCR to test for M genitalium among a pilot sample of 50 women with nongonococcal, nonchlamydial endometritis enrolled in the PID evaluation and clinical health (PEACH) study. All participants had pelvic pain, pelvic organ tenderness, and Leukorrhea, mucopurulent cervicitis, or untreated cervicitis. Endometritis was defined as ≥5surface epithelium neutrophils per ×400 field absent of menstrual endometrium and/or ≥2 stromal plasma cells per ×120 field. We detected M genitalium in 7 (14%) of the women tested: 6 (12%) in cervical specimens and 4 (8%) in endometrial specimens. We conclude that M genitalium is prevalent in the endometrium of women with nongonococcal, nonchlamydial PID. Copyright © 2006 Catherine L. Haggerty et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

  • a cluster analysis of bacterial vaginosis associated microflora and pelvic inflammatory disease
    American Journal of Epidemiology, 2005
    Co-Authors: Roberta B Ness, Sharon L Hillier, Carol A Stamm, Peter A Rice, Holly E Richter
    Abstract:

    : Controversy surrounds the association between bacterial vaginosis (BV) and pelvic inflammatory disease (PID). Women (N = 1,140) were ascertained at five US centers, enrolled (1999-2001), and followed up for a median of 3 years. Serial vaginal swabs were obtained for Gram's stain and cultures. PID was defined as 1) histologic endometritis or 2) pelvic pain and tenderness plus oral temperature >38.8 degrees C, Leukorrhea or mucopus, erythrocyte sedimentation rate >15 mm/hour, white blood cell count >10,000, or gonococcal/chlamydial lower genital infection. Exploratory factor analysis identified two discrete clusters of genital microorganisms. The first correlated with BV by Gram's stain and consisted of the absence of hydrogen peroxide-producing lactobacillus, Gardnerella vaginalis, Mycoplasma hominis, anaerobic gram-negative rods, and, to a lesser degree, Ureaplasma urealyticum. The second, unrelated to BV by Gram's stain, consisted of Enterococcus species and Escherichia coli. Being in the highest tertile in terms of growth of BV-associated microorganisms increased PID risk (adjusted rate ratio = 2.03, 95% confidence interval: 1.16, 3.53). Carriage of non-BV-associated microorganisms did not increase PID risk. Women with heavy growth of BV-associated microorganisms and a new sexual partner appeared to be at particularly high risk (adjusted rate ratio = 8.77, 95% confidence interval: 1.11, 69.2). When identified by microbial culture, a combination of BV-related microorganisms significantly elevated the risk of acquiring PID.

  • A cluster analysis of bacterial vaginosisassociated microflora and pelvic inflammatory disease
    2005
    Co-Authors: Roberta B Ness, Sharon L Hillier, David E. Soper, Carol A Stamm, Richard L Sweet, Kevin E. Kip, Peter Rice, Holly E Richter
    Abstract:

    Controversy surrounds the association between bacterial vaginosis (BV) and pelvic inflammatory disease (PID). Women (N 1,140) were ascertained at five US centers, enrolled (1999–2001), and followed up for a median of 3 years. Serial vaginal swabs were obtained for Gram’s stain and cultures. PID was defined as 1) histologic endometritis or 2) pelvic pain and tenderness plus oral temperature>38.8C, Leukorrhea or mucopus, erythrocyte sedimentation rate>15mm/hour, white blood cell count>10,000, or gonococcal/chlamydial lower genital infection. Exploratory factor analysis identified two discrete clusters of genital microorganisms. The first correlated with BV by Gram’s stain and consisted of the absence of hydrogen peroxide–producing lactobacillus, Gardnerella vaginalis, Mycoplasma hominis, anaerobic Gram-negative rods, and, to a lesser degree, Ureaplasma urealyticum. The second, unrelated to BV by Gram’s stain, consisted of Enterococcus species and Escherichia coli. Being in the highest tertile in terms of growth of BV-associated microorganisms increased PID risk (adjusted rate ratio 2.03, 95 % confidence interval: 1.16, 3.53). Carriage of non-BV-associated microorganisms did not increase PID risk. Women with heavy growth of BV-associated microorganisms and a new sexual partner appeared to be at partic-ularly high risk (adjusted rate ratio 8.77, 95 % confidence interval: 1.11, 69.2). When identified by microbia

Cahyaningtyas, Widia A. A. - One of the best experts on this subject based on the ideXlab platform.

  • Hubungan Antara Pengetahuan, Sikap dan Praktik Personal Hygiene Organ Genitalia Eksterna Terhadap Kejadian Keputihan Patologis
    'UKI Press', 2021
    Co-Authors: Cahyaningtyas, Widia A. A., Nainggolan Sudung, Simanjuntak, Tigor P.
    Abstract:

    Abstrak Keputihan (leukorea, flour albus, vaginal discharge) adalah sekret berlebihan dari vagina selain darah haid, dan tidak disebabkan neoplasma atau penyakit sistemik. Keputihan merupakan masalah kesehatan reproduksi dialami hampir 75%  perempuan didunia, paling tidak sekali selama hidupnya. Kurangnya pengetahuan, sikap, dan praktik dalam perawatan vagina diyakini berpengaruh terhadap kejadian keputihan patologis tersebut. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap, dan praktik personal hygiene organ genital eksterna terhadap kejadian keputihan patologis pada mahasiswi Fakultas Kedokteran Universitas Kristen Indonesia. Penelitian ini menggunakan desain penelitian analitik korelasional pada 98 mahasiswi. Terdapathubungan yang bermakna (p= 0,000) dan korelasi positif antara tingkat pengetahuan, sikap dan praktik personal hygiene dengan kejadian keputihan patologis.   Kata Kunci : keputihan, pengetahuan, sikap, praktik, personal hygiene.   Relationship Between Knowledge, Attitudes and Personal Practices of External Genitalia Hygiene Against Pathological Leucorrhoea   Abstract Vaginal discharge (Leukorrhea, flour albus, vaginal discharge) is excessive discharge from the vagina other than menstrual blood, and is not caused by neoplasms or systemic disease. Leucorrhoea is a reproductive health problem that affects nearly 75% of women in the world, at least once in their lifetime. Lack of knowledge, attitude, and practice in vaginal care is believed to have an effect on the incidence of pathological vaginal discharge. This study aims to determine the relationship between knowledge, attitudes, and personal hygiene practices of external genital organs on the incidence of pathological vaginal discharge in students of the Faculty of Medicine, Christian University of Indonesia. This study used a correlational analytical research design on 98 female students of the Faculty of Medicine, Christian University of Indonesia. It was found a significant relationship (p = 0.000) and a positive correlation between the level of knowledge, attitudes and personal hygiene practices with the incidence of pathological vaginal discharge.   Keywords: leucorrhoea, knowledge, attitude, practice, personal hygiene

  • Hubungan Antara Pengetahuan, Sikap dan Praktik Personal Hygiene Organ Genitalia Eksterna Terhadap Kejadian Keputihan Patologis
    'UKI Press', 2020
    Co-Authors: Cahyaningtyas, Widia A. A., Nainggolan Sudung, Simanjuntak, Tigor Peniel
    Abstract:

    Keputihan (leukorea, flour albus, vaginal discharge) adalah sekret berlebihan dari vagina selain darah haid, dan tidak disebabkan neoplasma atau penyakit sistemik. Keputihan merupakan masalah kesehatan reproduksi dialami hampir 75% perempuan didunia, paling tidak sekali selama hidupnya. Kurangnya pengetahuan, sikap, dan praktik dalam perawatan vagina diyakini berpengaruh terhadap kejadian keputihan patologis tersebut. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap, dan praktik personal hygiene organ genital eksterna terhadap kejadian keputihan patologis pada mahasiswi Fakultas Kedokteran Universitas Kristen Indonesia. Penelitian ini menggunakan desain penelitian analitik korelasional pada 98 mahasiswi. Terdapathubungan yang bermakna (p= 0,000) dan korelasi positif antara tingkat pengetahuan, sikap dan praktik personal hygiene dengan kejadian keputihan patologis. Kata Kunci : keputihan, pengetahuan, sikap, praktik, personal hygiene./Vaginal discharge (Leukorrhea, flour albus, vaginal discharge) is excessive discharge from the vagina other than menstrual blood, and is not caused by neoplasms or systemic disease. Leucorrhoea is a reproductive health problem that affects nearly 75% of women in the world, at least once in their lifetime. Lack of knowledge, attitude, and practice in vaginal care is believed to have an effect on the incidence of pathological vaginal discharge. This study aims to determine the relationship between knowledge, attitudes, and personal hygiene practices of external genital organs on the incidence of pathological vaginal discharge in students of the Faculty of Medicine, Christian University of Indonesia. This study used a correlational analytical research design on 98 female students of the Faculty of Medicine, Christian University of Indonesia. It was found a significant relationship (p = 0.000) and a positive correlation between the level of knowledge, attitudes and personal hygiene practices with the incidence of pathological vaginal discharge. Keywords: leucorrhoea, knowledge, attitude, practice, personal hygien

Catherine L Haggerty - One of the best experts on this subject based on the ideXlab platform.

  • mycoplasma genitalium among women with nongonococcal nonchlamydial pelvic inflammatory disease
    Infectious Diseases in Obstetrics & Gynecology, 2006
    Co-Authors: Catherine L Haggerty, Patricia A. Totten, Roberta B Ness
    Abstract:

    Pelvic inflammatory disease (PID) is a frequent condition of young women, often resulting in reproductive morbidity. Although Neisseria gonorrhoeae and/or Chlamydia trachomatis are/is recovered from approximately a third to a half of women with PID, the etiologic agent is often unidentified. We need PCR to test for M genitalium among a pilot sample of 50 women with nongonococcal, nonchlamydial endometritis enrolled in the PID evaluation and clinical health (PEACH) study. All participants had pelvic pain, pelvic organ tenderness, and Leukorrhea, mucopurulent cervicitis, or untreated cervicitis. Endometritis was defined as ≥5 surface epithelium neutrophils per ×400 field absent of menstrual endometrium and/or ≥2 stromal plasma cells per ×120 field. We detected M genitalium in 7 (14%) of the women tested: 6 (12%) in cervical specimens and 4 (8%) in endometrial specimens. We conclude that M genitalium is prevalent in the endometrium of women with nongonococcal, nonchlamydial PID.

  • Clinical Study Mycoplasma Genitalium Among Women With Nongonococcal, Nonchlamydial Pelvic Inflammatory Disease
    2006
    Co-Authors: Catherine L Haggerty, Patricia A. Totten, Sabina G. Astete, Roberta B Ness
    Abstract:

    Pelvic inflammatory disease (PID) is a frequent condition of young women, often resulting in reproductive morbidity. Although Neisseria gonorrhoeae and/or Chlamydia trachomatis are/is recovered from approximately a third to a half of women with PID, the etiologic agent is often unidentified. We need PCR to test for M genitalium among a pilot sample of 50 women with nongonococcal, nonchlamydial endometritis enrolled in the PID evaluation and clinical health (PEACH) study. All participants had pelvic pain, pelvic organ tenderness, and Leukorrhea, mucopurulent cervicitis, or untreated cervicitis. Endometritis was defined as ≥5surface epithelium neutrophils per ×400 field absent of menstrual endometrium and/or ≥2 stromal plasma cells per ×120 field. We detected M genitalium in 7 (14%) of the women tested: 6 (12%) in cervical specimens and 4 (8%) in endometrial specimens. We conclude that M genitalium is prevalent in the endometrium of women with nongonococcal, nonchlamydial PID. Copyright © 2006 Catherine L. Haggerty et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

  • endometritis does not predict reproductive morbidity after pelvic inflammatory disease
    American Journal of Obstetrics and Gynecology, 2003
    Co-Authors: Catherine L Haggerty, Robert L Holley, Jeffrey Peipert, Hugh Randall, Antonio J Amortegui, Roberta B Ness, Susan L Hendrix, Steven J Sondheimer
    Abstract:

    Abstract Objective: We investigated the association between endometritis and reproductive morbidity. Study Design: Participants were 614 women in the PID Evaluation and Clinical Health (PEACH) Study with pelvic pain, pelvic organ tenderness, and Leukorrhea, mucopurulent cervicitis, or untreated cervicitis. We compared women with endometritis (≥5 neutrophils or ≥2 plasma cells), Neisseria gonorrhoeae or Chlamydia trachomatis upper genital tract infection (UGTI) or both to women without endometritis/UGTI for outcomes of pregnancy, infertility, recurrent pelvic inflammatory disease (PID), and chronic pelvic pain (CPP), adjusting for age, race, education, PID history, and baseline infertility. Results: Endometritis/UGTI was not associated with reduced pregnancy (odds ratio [OR] 0.8, 95% CI 0.6-1.2) or elevated infertility (OR 1.0, 95% CI 0.6-1.6), recurrent PID (OR 0.6, 95% CI 0.4-0.9), or CPP (OR 0.6, 95% CI 0.4-0.9). PEACH participants with and without endometritis/UGTI had higher age- and race-specific pregnancy rates than 1997 national rates. Conclusion: Among women with clinically suspected mild-to-moderate PID treated with standard antibiotics, endometritis/UGTI was not associated with reproductive morbidity. (Am J Obstet Gynecol 2003;188:141-8.)

Simanjuntak, Tigor Peniel - One of the best experts on this subject based on the ideXlab platform.

  • Hubungan Antara Pengetahuan, Sikap dan Praktik Personal Hygiene Organ Genitalia Eksterna Terhadap Kejadian Keputihan Patologis
    'UKI Press', 2020
    Co-Authors: Cahyaningtyas, Widia A. A., Nainggolan Sudung, Simanjuntak, Tigor Peniel
    Abstract:

    Keputihan (leukorea, flour albus, vaginal discharge) adalah sekret berlebihan dari vagina selain darah haid, dan tidak disebabkan neoplasma atau penyakit sistemik. Keputihan merupakan masalah kesehatan reproduksi dialami hampir 75% perempuan didunia, paling tidak sekali selama hidupnya. Kurangnya pengetahuan, sikap, dan praktik dalam perawatan vagina diyakini berpengaruh terhadap kejadian keputihan patologis tersebut. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap, dan praktik personal hygiene organ genital eksterna terhadap kejadian keputihan patologis pada mahasiswi Fakultas Kedokteran Universitas Kristen Indonesia. Penelitian ini menggunakan desain penelitian analitik korelasional pada 98 mahasiswi. Terdapathubungan yang bermakna (p= 0,000) dan korelasi positif antara tingkat pengetahuan, sikap dan praktik personal hygiene dengan kejadian keputihan patologis. Kata Kunci : keputihan, pengetahuan, sikap, praktik, personal hygiene./Vaginal discharge (Leukorrhea, flour albus, vaginal discharge) is excessive discharge from the vagina other than menstrual blood, and is not caused by neoplasms or systemic disease. Leucorrhoea is a reproductive health problem that affects nearly 75% of women in the world, at least once in their lifetime. Lack of knowledge, attitude, and practice in vaginal care is believed to have an effect on the incidence of pathological vaginal discharge. This study aims to determine the relationship between knowledge, attitudes, and personal hygiene practices of external genital organs on the incidence of pathological vaginal discharge in students of the Faculty of Medicine, Christian University of Indonesia. This study used a correlational analytical research design on 98 female students of the Faculty of Medicine, Christian University of Indonesia. It was found a significant relationship (p = 0.000) and a positive correlation between the level of knowledge, attitudes and personal hygiene practices with the incidence of pathological vaginal discharge. Keywords: leucorrhoea, knowledge, attitude, practice, personal hygien

Simanjuntak, Tigor P. - One of the best experts on this subject based on the ideXlab platform.

  • Hubungan Antara Pengetahuan, Sikap dan Praktik Personal Hygiene Organ Genitalia Eksterna Terhadap Kejadian Keputihan Patologis
    'UKI Press', 2021
    Co-Authors: Cahyaningtyas, Widia A. A., Nainggolan Sudung, Simanjuntak, Tigor P.
    Abstract:

    Abstrak Keputihan (leukorea, flour albus, vaginal discharge) adalah sekret berlebihan dari vagina selain darah haid, dan tidak disebabkan neoplasma atau penyakit sistemik. Keputihan merupakan masalah kesehatan reproduksi dialami hampir 75%  perempuan didunia, paling tidak sekali selama hidupnya. Kurangnya pengetahuan, sikap, dan praktik dalam perawatan vagina diyakini berpengaruh terhadap kejadian keputihan patologis tersebut. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap, dan praktik personal hygiene organ genital eksterna terhadap kejadian keputihan patologis pada mahasiswi Fakultas Kedokteran Universitas Kristen Indonesia. Penelitian ini menggunakan desain penelitian analitik korelasional pada 98 mahasiswi. Terdapathubungan yang bermakna (p= 0,000) dan korelasi positif antara tingkat pengetahuan, sikap dan praktik personal hygiene dengan kejadian keputihan patologis.   Kata Kunci : keputihan, pengetahuan, sikap, praktik, personal hygiene.   Relationship Between Knowledge, Attitudes and Personal Practices of External Genitalia Hygiene Against Pathological Leucorrhoea   Abstract Vaginal discharge (Leukorrhea, flour albus, vaginal discharge) is excessive discharge from the vagina other than menstrual blood, and is not caused by neoplasms or systemic disease. Leucorrhoea is a reproductive health problem that affects nearly 75% of women in the world, at least once in their lifetime. Lack of knowledge, attitude, and practice in vaginal care is believed to have an effect on the incidence of pathological vaginal discharge. This study aims to determine the relationship between knowledge, attitudes, and personal hygiene practices of external genital organs on the incidence of pathological vaginal discharge in students of the Faculty of Medicine, Christian University of Indonesia. This study used a correlational analytical research design on 98 female students of the Faculty of Medicine, Christian University of Indonesia. It was found a significant relationship (p = 0.000) and a positive correlation between the level of knowledge, attitudes and personal hygiene practices with the incidence of pathological vaginal discharge.   Keywords: leucorrhoea, knowledge, attitude, practice, personal hygiene