The Experts below are selected from a list of 318 Experts worldwide ranked by ideXlab platform
Ilona J. Frieden - One of the best experts on this subject based on the ideXlab platform.
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Lichen Striatus : simultaneous occurrence in siblings
Pediatrics, 1992Co-Authors: John T. Kanegaye, Ilona J. FriedenAbstract:Lichen Striatus is a benign, self-limited linear dermatosis of unknown etiology seen primarily in children. We report here the unusual simultaneous occurrence of this condition in siblings, a manifestation which may offer insight into the pathogenesis of this condition. CASE REPORTS Patient 1 A 2-year-old Japanese girl had a nonpruritic 0.5 x 5 cm hypopigmented band located on the right wrist and forearm, which had been present for several weeks. The past medical history was unremarkable, but family history was notable for atopic disease: asthma in a cousin and allergic rhinitis in her mother. A clinical diagnosis of Lichen Striatus was made, and the patient was observed without treatment.
Akira Ishibashi - One of the best experts on this subject based on the ideXlab platform.
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Facial Lichen Striatus: successful treatment with tacrolimus ointment
The British journal of dermatology, 2003Co-Authors: Norihiro Fujimoto, Shingo Tajima, Akira IshibashiAbstract:We report a 22-year-old Japanese woman with facial Lichen Striatus (LS). The distribution of the lesions corresponded to that of Blaschko's lines. Histology of the lesional skin showed an inflammatory cell infiltrate around hair follicles and eccrine glands. Treatment of the linear lesions with tacrolimus ointment once or twice daily resulted in a dramatical improvement in a short time. LS is a T-cell-mediated inflammatory disease and tacrolimus ointment may be an effective alternative treatment for this disease especially when the lesions are located on the face.
John T. Kanegaye - One of the best experts on this subject based on the ideXlab platform.
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Lichen Striatus : simultaneous occurrence in siblings
Pediatrics, 1992Co-Authors: John T. Kanegaye, Ilona J. FriedenAbstract:Lichen Striatus is a benign, self-limited linear dermatosis of unknown etiology seen primarily in children. We report here the unusual simultaneous occurrence of this condition in siblings, a manifestation which may offer insight into the pathogenesis of this condition. CASE REPORTS Patient 1 A 2-year-old Japanese girl had a nonpruritic 0.5 x 5 cm hypopigmented band located on the right wrist and forearm, which had been present for several weeks. The past medical history was unremarkable, but family history was notable for atopic disease: asthma in a cousin and allergic rhinitis in her mother. A clinical diagnosis of Lichen Striatus was made, and the patient was observed without treatment.
J C Morenogimenez - One of the best experts on this subject based on the ideXlab platform.
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adult blaschkitis Lichen Striatus successfully treated with topical tacrolimus
Actas Dermo-Sifiliográficas, 2009Co-Authors: A Tejeravaquerizo, I Ruizmolina, Eduardo Solisgarcia, J C MorenogimenezAbstract:To the Editor: Lichen Striatus is a self-limiting inflammatory dermatosis that is characteristically distributed along the Blaschko lines. It is usually seen in children although cases, with different histopathological features, have been reported in adults. In view of the characteristic clinical features of the disease in adults—with its papulovesicular aspect—it is known as blaschkitis. Subsequently, different attempts have been made to define these conditions. A 70-year-old man with a family and personal history of atopy attended the clinic for a pruriginous multilinear papulovesicular eruption on the trunk and right leg that had appeared 6 months earlier. Treatment over the preceding month with methylprednisolone aceponate applied as a 0.1% cream had led to no improvement. The multilinear eruption took the form of a papulovesicular eruption that followed the Blaschko lines on one side of the body; it was more intense on the leg (Figures 1A, C, and E). Histopathological study showed a Lichenoid inflammatory infiltrate that extended to the mid-dermis (Figure 2A). The composition of this infiltrate was polymorphous, with the presence of lymphocytes, plasma cells, histiocytes, and a notable presence of eosinophils. The epidermis showed irregular epidermal hyperplasia, with compact hypergranulosis and hyperkeratosis but no parakeratosis. Limited spongiosis was present. No transepidermal migration of inflammatory cells was observed. In addition, clefts were observed between the dermis and epidermis, along with basal apoptotic keratinocytes and pigmentary incontinence (Figure 2B). Perieccrine thickening of the deep dermis was observed. Once Lichen Striatus had been diagnosed, the patient was instructed to apply an ointment containing 0.1% tacrolimus twice a day for the first month to the lesions on the trunk, which disappeared, and to the legs in the second month, with the same results (Figures 1B, D, and F). After 6 months of follow-up, no recurrences had been reported.
Norihiro Fujimoto - One of the best experts on this subject based on the ideXlab platform.
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Facial Lichen Striatus: successful treatment with tacrolimus ointment
The British journal of dermatology, 2003Co-Authors: Norihiro Fujimoto, Shingo Tajima, Akira IshibashiAbstract:We report a 22-year-old Japanese woman with facial Lichen Striatus (LS). The distribution of the lesions corresponded to that of Blaschko's lines. Histology of the lesional skin showed an inflammatory cell infiltrate around hair follicles and eccrine glands. Treatment of the linear lesions with tacrolimus ointment once or twice daily resulted in a dramatical improvement in a short time. LS is a T-cell-mediated inflammatory disease and tacrolimus ointment may be an effective alternative treatment for this disease especially when the lesions are located on the face.