The Experts below are selected from a list of 152961 Experts worldwide ranked by ideXlab platform

Sylvain Gigan - One of the best experts on this subject based on the ideXlab platform.

  • non invasive focusing and imaging in scattering media with a fluorescence based transmission matrix
    Nature Communications, 2020
    Co-Authors: Antoine Boniface, Jonathan Dong, Sylvain Gigan
    Abstract:

    In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The Transmission Matrix approach has shown its capability to inverse the effect of scattering and efficiently focus light. In practice, the matrix is usually measured using an invasive detector or low-resolution acoustic guide stars. Here, we introduce a non-invasive and all-optical strategy based on Linear fluorescence to reconstruct the transmission matrices, to and from a fluorescent object placed inside a scattering medium. It consists in demixing the incoherent patterns emitted by the object using low-rank factorizations and phase retrieval algorithms. We experimentally demonstrate the efficiency of this method through robust and selective focusing. Additionally, from the same measurements, it is possible to exploit memory effect correlations to image and reconstruct extended objects. This approach opens up a new route towards imaging in scattering media with Linear or non-Linear Contrast mechanisms. Light scattering represents the main limitation to image at depth in biological microscopy. The authors present a strategy to characterize light propagation in and out of a scattering medium based on Linear fluorescence feedback and from the same measurements exploit memory effect correlations to image and reconstruct extended objects.

  • non invasive focusing and imaging in scattering media with a fluorescence based transmission matrix
    arXiv: Optics, 2020
    Co-Authors: Antoine Boniface, Jonathan Dong, Sylvain Gigan
    Abstract:

    In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The Transmission Matrix approach has shown its capability to inverse the effect of scattering and efficiently focus light. In practice, the matrix is usually measured using an invasive detector or low-resolution acoustic guide stars. Here, we introduce a non-invasive and all-optical strategy based on Linear fluorescence to reconstruct the transmission matrices, to and from a fluorescent object placed inside a scattering medium. It consists in demixing the incoherent patterns emitted by the object using low-rank factorizations and phase retrieval algorithms. We experimentally demonstrate the efficiency of this method through robust and selective focusing. Additionally, from the same measurements, it is possible to exploit memory effect correlations to image and reconstruct extended objects. This approach opens up a new route towards imaging in scattering media with Linear or non-Linear Contrast mechanisms.

Scott B Reeder - One of the best experts on this subject based on the ideXlab platform.

  • gadolinium deposition in the brain summary of evidence and recommendations
    Lancet Neurology, 2017
    Co-Authors: Vikas Gulani, Fernando Calamante, Frank G Shellock, Emanuel Kanal, Scott B Reeder
    Abstract:

    Emerging evidence has linked MRI signal changes in deep nuclei of the brain with repeated administration of gadolinium-based Contrast agents. Gadolinium deposits have been confirmed in brain tissue, most notably in the dentate nuclei and globus pallidus. Although some Linear Contrast agents appear to cause greater MRI signal changes than some macrocyclic agents, deposition of gadolinium has also been observed with macrocyclic agents. However, the extent of gadolinium deposition varies between agents. Furthermore, the clinical significance of the retained gadolinium in the brain, if any, remains unknown. No data are available in human beings or animals to show adverse clinical effects due to the gadolinium deposition in the brain. On behalf of the International Society for Magnetic Resonance in Medicine, we present recommendations for the clinical and research use of gadolinium-based Contrast agents. These recommendations might evolve as new evidence becomes available.

Antoine Boniface - One of the best experts on this subject based on the ideXlab platform.

  • non invasive focusing and imaging in scattering media with a fluorescence based transmission matrix
    Nature Communications, 2020
    Co-Authors: Antoine Boniface, Jonathan Dong, Sylvain Gigan
    Abstract:

    In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The Transmission Matrix approach has shown its capability to inverse the effect of scattering and efficiently focus light. In practice, the matrix is usually measured using an invasive detector or low-resolution acoustic guide stars. Here, we introduce a non-invasive and all-optical strategy based on Linear fluorescence to reconstruct the transmission matrices, to and from a fluorescent object placed inside a scattering medium. It consists in demixing the incoherent patterns emitted by the object using low-rank factorizations and phase retrieval algorithms. We experimentally demonstrate the efficiency of this method through robust and selective focusing. Additionally, from the same measurements, it is possible to exploit memory effect correlations to image and reconstruct extended objects. This approach opens up a new route towards imaging in scattering media with Linear or non-Linear Contrast mechanisms. Light scattering represents the main limitation to image at depth in biological microscopy. The authors present a strategy to characterize light propagation in and out of a scattering medium based on Linear fluorescence feedback and from the same measurements exploit memory effect correlations to image and reconstruct extended objects.

  • non invasive focusing and imaging in scattering media with a fluorescence based transmission matrix
    arXiv: Optics, 2020
    Co-Authors: Antoine Boniface, Jonathan Dong, Sylvain Gigan
    Abstract:

    In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The Transmission Matrix approach has shown its capability to inverse the effect of scattering and efficiently focus light. In practice, the matrix is usually measured using an invasive detector or low-resolution acoustic guide stars. Here, we introduce a non-invasive and all-optical strategy based on Linear fluorescence to reconstruct the transmission matrices, to and from a fluorescent object placed inside a scattering medium. It consists in demixing the incoherent patterns emitted by the object using low-rank factorizations and phase retrieval algorithms. We experimentally demonstrate the efficiency of this method through robust and selective focusing. Additionally, from the same measurements, it is possible to exploit memory effect correlations to image and reconstruct extended objects. This approach opens up a new route towards imaging in scattering media with Linear or non-Linear Contrast mechanisms.

Fernando Calamante - One of the best experts on this subject based on the ideXlab platform.

  • gadolinium deposition in the brain summary of evidence and recommendations
    Lancet Neurology, 2017
    Co-Authors: Vikas Gulani, Fernando Calamante, Frank G Shellock, Emanuel Kanal, Scott B Reeder
    Abstract:

    Emerging evidence has linked MRI signal changes in deep nuclei of the brain with repeated administration of gadolinium-based Contrast agents. Gadolinium deposits have been confirmed in brain tissue, most notably in the dentate nuclei and globus pallidus. Although some Linear Contrast agents appear to cause greater MRI signal changes than some macrocyclic agents, deposition of gadolinium has also been observed with macrocyclic agents. However, the extent of gadolinium deposition varies between agents. Furthermore, the clinical significance of the retained gadolinium in the brain, if any, remains unknown. No data are available in human beings or animals to show adverse clinical effects due to the gadolinium deposition in the brain. On behalf of the International Society for Magnetic Resonance in Medicine, we present recommendations for the clinical and research use of gadolinium-based Contrast agents. These recommendations might evolve as new evidence becomes available.

Peter Ercius - One of the best experts on this subject based on the ideXlab platform.

  • efficient Linear phase Contrast in scanning transmission electron microscopy with matched illumination and detector interferometry
    Nature Communications, 2016
    Co-Authors: Colin Ophus, Jim Ciston, Jordan S Pierce, Tyler R Harvey, Jordan Chess, Benjamin J Mcmorran, Cory Czarnik, Harald Rose, Peter Ercius
    Abstract:

    The ability to image light elements in soft matter at atomic resolution enables unprecedented insight into the structure and properties of molecular heterostructures and beam-sensitive nanomaterials. In this study, we introduce a scanning transmission electron microscopy technique combining a pre-specimen phase plate designed to produce a probe with structured phase with a high-speed direct electron detector to generate nearly Linear Contrast images with high efficiency. We demonstrate this method by using both experiment and simulation to simultaneously image the atomic-scale structure of weakly scattering amorphous carbon and strongly scattering gold nanoparticles. Our method demonstrates strong Contrast for both materials, making it a promising candidate for structural determination of heterogeneous soft/hard matter samples even at low electron doses comparable to traditional phase-Contrast transmission electron microscopy. Simulated images demonstrate the extension of this technique to the challenging problem of structural determination of biological material at the surface of inorganic crystals.